International Journal of Health Sciences-IJHS最新文献

{"title":"Clinical application of transarterial chemoembolization combined with terminal branches portal vein embolization in planned hepatectomy","authors":"Guoqing Zhu, Wenhao Hu, Wei Xiang, Junwei Ni, Liyang Dong","doi":"10.53730/ijhs.v7ns1.14563","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14563","url":null,"abstract":"This study aimed to investigate the clinical efficacy of transarterial chemoembolization (TACE) in conjunction with terminal branches portal vein embolization (TBPVE) in the context of planned hepatectomy. A cohort of five patients afflicted by primary hepatocellular carcinoma who were deemed unsuitable candidates for primary surgical resection was gathered from August 2019 to December 2021. Following the application of TACE in combination with TBPVE as a therapeutic intervention, we observed postoperative general reactions, alterations in tumor biomarkers, hyperplasia of future liver remnant (FLR), and subsequent surgical resection. All patients successfully underwent the combined TACE and TBPVE procedure, achieving a technical success rate of 100%. One week after TACE, alpha-fetoprotein (AFP) levels decreased from 38.52±49.21 to 25.27±37.94 μg/L, and Protein Induced by Vitamin K Absence or Antagonist (PIVKA) levels decreased from 1689.30±1663.83 to 219.03±228.10 μg/L. Two weeks post-TBPVE, FLR exhibited an increment from 350.80±41.17 to 476.00±57.91 mL. The ratio of FLR to standard liver volume (SLV) increased from 30.94%±3.63% to 42.03%±5.62%. The combined application of TACE and TBPVE not only effectively manages tumor progression but also augments the FLR, thereby affording patients with a limited future liver remnant an opportunity for surgical resection of hepatocellular carcinoma.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135045843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical application of transarterial chemoembolization combined with terminal branches portal vein embolization in planned hepatectomy","authors":"Guoqing Zhu, Wenhao Hu, Wei Xiang, Junwei Ni, Liyang Dong","doi":"10.53730/ijhs.v7n3.14563","DOIUrl":"https://doi.org/10.53730/ijhs.v7n3.14563","url":null,"abstract":"This study aimed to investigate the clinical efficacy of transarterial chemoembolization (TACE) in conjunction with terminal branches portal vein embolization (TBPVE) in the context of planned hepatectomy. A cohort of five patients afflicted by primary hepatocellular carcinoma who were deemed unsuitable candidates for primary surgical resection was gathered from August 2019 to December 2021. Following the application of TACE in combination with TBPVE as a therapeutic intervention, we observed postoperative general reactions, alterations in tumor biomarkers, hyperplasia of future liver remnant (FLR), and subsequent surgical resection. All patients successfully underwent the combined TACE and TBPVE procedure, achieving a technical success rate of 100%. One week after TACE, alpha-fetoprotein (AFP) levels decreased from 38.52±49.21 to 25.27±37.94 μg/L, and Protein Induced by Vitamin K Absence or Antagonist (PIVKA) levels decreased from 1689.30±1663.83 to 219.03±228.10 μg/L. Two weeks post-TBPVE, FLR exhibited an increment from 350.80±41.17 to 476.00±57.91 mL. The ratio of FLR to standard liver volume (SLV) increased from 30.94%±3.63% to 42.03%±5.62%. The combined application of TACE and TBPVE not only effectively manages tumor progression but also augments the FLR, thereby affording patients with a limited future liver remnant an opportunity for surgical resection of hepatocellular carcinoma.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135149536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of ginseng in pancreatic cancer metastasis","authors":"Shengzhang Lin, Zhaohong Wang, Xufan Cai","doi":"10.53730/ijhs.v7n3.14490","DOIUrl":"https://doi.org/10.53730/ijhs.v7n3.14490","url":null,"abstract":"It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135250979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mechanisms of ginseng in pancreatic cancer metastasis","authors":"Zhaohong Wang, Xufan Cai, Shengzhang Lin","doi":"10.53730/ijhs.v7ns1.14490","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14490","url":null,"abstract":"It has been shown that ginsenosides can inhibit proliferation, migration, and invasion of pancreatic cancer (PC) cells, and promote apoptosis of PC cells. However, the potential mechanisms of ginseng in treating PC metastasis (PCM) have not been fully elucidated. In this study, we employed an integrated bioinformatics approach of network pharmacology analysis. By selecting common targets of diseases and drugs, a drug-component-target-disease network was constructed to analyze the biological functions and signaling pathways involved in the targets. A total of 6 PC samples were includedd, which were divided into primary PC group (PANC-1, n=3) and metastatic PC group. A total of 9263 differentially expressed genes (DEGs) and 14 PC target genes were identified. According to the network pharmacology analysis, we found that ginsenoside Rg3 was associated with the treatment of PCM and identified 6 potential targets. Among them, CD44, EGFR, KRAS, and PRNP were the main DEGs related to the treatment of PC by ginsenoside Rg3. These genes were mainly enriched in the Proteoglycans in Cancer pathway, and KRAS, EGFR, and CD44 were upregulated in the pathway, which may be affected by the ginsenoside Rg3. This provides a new direction for further research on the mechanisms of ginseng in PCM.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"66 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135198051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foley catheter for induction of labor after cesarean section","authors":"Loai. N. Said, Elham A. Al Atrash","doi":"10.53730/ijhs.v7ns1.14588","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14588","url":null,"abstract":"Induction of labor may be necessary in around twenty-five to thirty percent of a woman's subsequent pregnancies when she has already given birth through cesarean section. During our research, the objective had been to ascertain the rate of spontaneous vaginal birth, rate of cesarean section, and rate of complications that followed the induction of labor with transcervical foley catheter in females who had previously had 1 cesarean section. This retrospective cohort trial was performed in the largest city in Palestine at a tertiary teaching hospital. In subsequent pregnancy, pregnant cases with a history of a prior CS delivery (n = 306) underwent labor induction at term with a Foley catheter. Women who underwent labor induction with transcervical foley catheter at Al-Ahli Hospital in Hebron, Palestine. From April 2017 until March 2020. Our research revealed that 46.7 percent of women had spontaneous vaginal births, 14.4 percent had assisted vaginal births, and one woman experienced uterine rupture. The frequency of postpartum hemorrhage is 30 percent, the most prevalent complication. 10 percent and 5 percent of mothers experienced intrapartum and postpartum infections, correspondingly. 5% of newborns had a confirmed infection, and there was one perinatal fatality related to uterine rupture.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"84 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135592504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Factors Associated with Low Birth Weight Among Neonates Born at Thika Level 5 Hospital in Kiambu County, Kenya","authors":"Joyce Osebe Kenyanya, Gideon Kikuvi, Peter Wanzala, Josephat Nyagero","doi":"10.47941/ijhs.1464","DOIUrl":"https://doi.org/10.47941/ijhs.1464","url":null,"abstract":"Purpose: To determine maternal factors associated with low birth weight among neonates born at Thika Level Five Hospital in Kiambu County, Kenya.
 Methodology: Cross sectional convergent design was employed. The target group composed of mothers who delivered in the hospital during the study period (July-August, 2019). Census method was used to recruit participants for a quantitative study. Purposive sampling was used to select participants for FGDs and KIIs. Sample size was determined using the Cochran formula. Desired sample size was 210 mothers which was adjusted to 215 participants. Independent variables included: socio-demographic, socio-economic, socio-cultural, behavioral, and health of the mothers. Dependent variable was LBW which was classified further into LBW, very LBW, extremely LBW. (UNICEF, 2010). Quantitative and qualitative data were analyzed using Stata statistical version 14, logistic regression and NVivo version 14 respectively,
 Findings: ≥35 years of mothers OR=13.67, p=0.018, CL [1.55-120.12] and the second born children OR=2.98; p=0.025; CL [1.15-7.73] were associated with the overall LBW. Secondary level education OR=0.35; p=0.03; CL [0.14-0.91] was a protection against LBW. Meru OR=17.429, p=0.016, CI [1.7162-176.991] and other tribes OR=10.479, p=0.048, CI [1.025-107.124] were associated with low birth weight. Hypertension OR=3.59; p=0.038; CL [0.14-0.91] and malaria (OR=51.250, p=0.005, CL [3.185-822.132]) were associated with very LBW. ANC-attendance (OR=0.068, p=0.37, CL [0.0055-0.845]) was a protection against extremely LBW OR= 0.07; p=0,037; CL [0.01-0.85].
 Unique Contribution to Theory, Policy and Practice: ≥35 years of mothers are risk factors for low birth weight. Second child is at risk of being low birth weight. Neonates of Meru origin and other minority ethnic groups in Thika are at risk of being LBW. Secondary level education is a protection against low birth weight. Hypertension and malaria are risk factors for very low birth weight. ANC-attendance is a protection against extremely low birth weight. The County Government of Kiambu should develop suitable strategies of strengthening maternal and child services at level one.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135695902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"importance of sports medicine in modern sports among Algerian teams","authors":"Ghidi Abdelkader","doi":"10.53730/ijhs.v7ns1.14583","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14583","url":null,"abstract":"Sports medicine is the science that studies the most important injuries that athletes may be exposed to During discussions or training. It also shows how these injuries can be prevented. In this study, the researcher has revealed the importance of this science in the mathematical sciences field, and revealed the importance of studying this science, then to benefit from the previous experiences of doctors in this significant specialty. Also, integrating it into the modern training methodology. The researcher followed the descriptive approach. The results were clear about the importance and role of sports medicine in the field of sports.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135372850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"efficacy of low energy fractional carbon dioxide laser therapy in management of post-surgical hypertrophic scars","authors":"Yamen Almeghawesh","doi":"10.53730/ijhs.v7ns1.14579","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14579","url":null,"abstract":"Background: aberrant & accelerated wound-healing process that results in hypertrophic scarring causes extracellular matrix & collagen to deposit abnormally in the dermis. After tissue damage occurs, a defensive reaction called tissue repair occurs. Aim; in this review; we aimed to present the effectiveness of low-energy fractional carbon dioxide laser therapy in treating hypertrophic scars following surgery. Summary: A safe & effective approach for treating hypertrophic burn scars is fractional ablative CO2 laser therapy. Even though more treatment sessions have been necessary for satisfying outcomes, a big improvement can be seen after just one round of therapy. Combination therapy with other modalities can decrease the need for repetition of therapy as efficacy increases. Though, in some studies, combination therapy may shorten the duration of studied case downtime & in others, combination therapy may increase side effects. essential for laser energy setting needs to be adjusted for each hypertrophic scar condition. larger research population & longer follow-up period are recommended.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136277909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combined superior and inferior dermoglandular flaps for projection enhancement in giantic breast amputation and free nipple areola graft","authors":"Yamen Almeghawesh","doi":"10.53730/ijhs.v7ns1.14577","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14577","url":null,"abstract":"Giantomastia has been a pathological condition in which excised breast tissue weighs more than1.5 kg per breast or when breast weight surpasses three percent of body weight. epidermis & Cooper's ligaments, which support breast tissue, expand as a result of breasts becoming heavier & larger, which causes breast ptosis. Numerous methods for correcting gigantomastia have been discovered. amputation for decreased studied cases who complain of gigantomastia & severe ptosis (space among nipple & inframammary fold exceeds twenty-five cm) are only eligible for mammaplasty with free nipple-areola grafting. purpose of that surgery is to achieve breast shape size that is acceptable while also relieving pain & suffering brought on by excessive breast tissue hypertrophy. flat, boxy breasts with poor projection is the main drawback of that treatment. Several flaps, including superior, inferior, medial, superomedial,& lateral-based flaps combined with wise-pattern skin excision, are employed to address this drawback.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135199758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"relationship between occlusion and posture","authors":"Mahmoud Mohamed Kamaleldin Mohamed Omar, Curtis Westersund, Fabio Savastano, Julio Suay Anton","doi":"10.53730/ijhs.v7ns1.14575","DOIUrl":"https://doi.org/10.53730/ijhs.v7ns1.14575","url":null,"abstract":"The stomatognathic system includes the relationship between teeth, masticatory muscles and temporomandibular joints with its relation with body and head posture. Aim of the study: This Systematic review is to research the relationship between occlusion and body posture. Materials and methods-Study design: This is a literature systematic review which is done after collecting more than 10 previous papers. Inclusion criteria: Papers explaining dental occlusion in details and its correlation with body and head posture. Exclusion criteria: Papers about occlusion focusing on occlusal splints and lab work. Conclusion: There is a strong relation between dental occlusion class, head, and body posture through PDL and the trigeminal nerve in the brain. Accordingly, the occlusion affects the posture and, more importantly, the position of the condyle in the temporal fossa. It was always believed that condyle position comes first then the occlusion, but it is the other way around.","PeriodicalId":47093,"journal":{"name":"International Journal of Health Sciences-IJHS","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135386510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}