Journal of Pregnancy最新文献

{"title":"Drug Utilization Studies in Pregnant Women for Newly Licensed Medicinal Products: A Contribution from IMI ConcePTION.","authors":"Sandra Lopez-Leon, Anja Geldhof, Julie Scotto, Keele Wurst, Meritxell Sabidó, Jingping Mo, Ditte Molgaard-Nielsen, Jorieke E H Bergman, Xuan Anh Phi, Sue Jordan","doi":"10.1155/2024/8862801","DOIUrl":"10.1155/2024/8862801","url":null,"abstract":"<p><strong>Purpose: </strong>Studies focusing on safety outcomes typically require large populations to comprehensively characterise the patient groups exposed to the medicines under investigation. However, there is often less information for subpopulations, such as pregnant or breastfeeding women, particularly when new medicines are considered. It is important to understand what information can be obtained from drug utilization studies (DUS) involving pregnant women in the early years postmarketing to provide supportive information for safety studies. The aims of this literature review are to (1) identify and review DUS for new medicines in pregnancy and breastfeeding and (2) list and summarise key information items to be reported in a DUS for new medicines in pregnancy.</p><p><strong>Methods: </strong>To identify postmarketing DUS of new prescription medicines or enantiomers in pregnancy, a systematic literature review was undertaken in PubMed and Embase between January 2015 and June 2022. In addition, the complete database of the ENCePP EU PAS Register was systematically searched to June 2022.</p><p><strong>Results: </strong>We identified 11 published DUS on new medicines in pregnancy from the ENCePP EU PAS Register and none from other sources. No studies on breastfeeding were identified. The 11 identified publications reported the medicine's use for the first 3 to 5 years after marketing approval. No reports assessed utilization in the first 3 years of approval. It was usual to issue interim reports annually (7 studies). All studies concerned conditions managed in ambulatory care (primary care and outpatient facilities) and included some primary care prescribing. Most (<i>n</i> = 8) only had prescribing/dispensing data available at individual level for ambulatory care; outpatient prescribing was included in three of these studies Three studies held a limited amount of in-hospital prescribing data. A DUS can confirm at an early stage whether there are sufficient exposed pregnancies in available data sources to ensure a safety study is powered to detect a difference in the prevalence of adverse pregnancy or infant outcomes or if additional data from other databases are needed. A DUS may also help address methodological considerations such as selection of comparators. DUS can be performed embedded in a DUS in the general population, in a cohort of women of childbearing age, or in a cohort of pregnant women.</p><p><strong>Conclusion: </strong>This review summarises key aspects of a DUS for new medicines in pregnancy. DUS for new medicines in pregnancy should be planned before marketing, scheduled for the first 3 to 5 years after release, with annual interim/progress reports, and reported in peer-reviewed journals. By offering detailed information on data sources, exposure timing, prevalence and location, coprescribing, comorbidities, coexposures, and demographics, a DUS will offer a firm foundation for safety studies and will help to contextualiz","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2024 ","pages":"8862801"},"PeriodicalIF":3.2,"publicationDate":"2024-01-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10796183/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139513892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Obesity Cut-Off Points Using Prepregnancy Body Mass Index according to Cardiometabolic Conditions in Pregnancy.","authors":"Renata O Neves, Alexandre da S Rocha, Bruna O de Vargas, Daniela C Kretzer, Salete de Matos, Marcelo Z Goldani, Lisia von Diemen, José A de A Magalhães, Juliana R Bernardi","doi":"10.1155/2023/6669700","DOIUrl":"https://doi.org/10.1155/2023/6669700","url":null,"abstract":"<p><strong>Aim: </strong>To suggest cut-off points for body mass index (BMI) using gestational hypertension, preeclampsia, and gestational diabetes mellitus (GDM) as cardiometabolic conditions in pregnancy.</p><p><strong>Methods: </strong>In this prospective study, singleton pregnant women from the fetal medicine service of the Brazilian Unified Health System were included. The pregnancy, perinatal, and newborn data were obtained from the clinical medical records. Maternal anthropometry included an assessment of weight and height and the prepregnancy BMI evaluation categorized according to the World Health Organization cut-off points. The area under the curve and confidence interval values from receiver operator curves were generated to identify the optimal cut-off points using prepregnancy BMI with better sensitivity and specificity.</p><p><strong>Results: </strong>Data on 218 pregnancies were analyzed, with 57.9% (<i>n</i> = 124) being classified as overweight/obese, 11% (<i>n</i> = 24) with GDM, 6.9% (<i>n</i> = 15) with preeclampsia, and 11.0% (<i>n</i> = 24) with gestational hypertension. The BMI cut-off points for predicting cardiometabolic conditions were 27.52 kg/m² (S: 66.7%; E: 63.8%) for women with GDM; 27.40 kg/m² (S: 73.3%; E: 62.4%; S: 79.2%; E: 64.9%; S: 70.3%; E: 66.3%) for women with preeclampsia, gestational hypertension, and gestational hypertension plus preeclampsia, respectively; and 27.96 kg/m² (S: 69.6%; E: 65.6%) for women with preeclampsia plus GDM.</p><p><strong>Conclusion: </strong>The findings suggest that the optimal prepregnancy BMI cut-off point is around 27 kg/m² for pregnant women with maternal cardiometabolic conditions.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"6669700"},"PeriodicalIF":3.2,"publicationDate":"2023-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10667054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Place of Delivery and Associated Factors among Pastoralists in Ethiopia: A Systematic Review and Meta-Analysis Evaluation","authors":"Lebeza Alemu Tenaw, Henok Kumsa, Mulugeta Wodaje Arage, Atitegeb Abera, Tilahun Hailu, Esuyawkal Mislu","doi":"10.1155/2023/2634610","DOIUrl":"https://doi.org/10.1155/2023/2634610","url":null,"abstract":"Background. Pastoralist communities rely on their livestock for at least 50% of their food supply and source of income. Home births raise the risk of maternal morbidity and death, whereas institutional births lessen the likelihood of difficulties during labor. Around 70% of labors in pastoralist regions of Ethiopia were assisted by traditional birth attendants. Methods. Studies done from January 2004 to January 2023, accessed in PubMed, EMBASE, Medline, and other search engines, were included. PRISMA guidelines and JBI critical appraisal checklist were used to assure the quality of the review. Ten articles were included in this review. Data were extracted with Excel and exported to STATA 16 for analysis. Heterogeneity of literatures was evaluated using <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M1\"> <msup> <mrow> <mi>I</mi> </mrow> <mrow> <mn>2</mn> </mrow> </msup> </math> statistics and publication bias using the Egger regression asymmetry test and the Duval and Tweedie trim-fill analysis. Statistical significance was declared at <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M2\"> <mi>p</mi> </math> value less than 0.05. Result. The pooled estimate of institutional delivery among the pastoralist community in Ethiopia is 21.2% (95% CI: 16.2-26.1). Husbands who were involved to decide place of delivery ( <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M3\"> <mtext>OR</mtext> <mo>=</mo> <mn>3.47</mn> </math> ; 95% CI: 1.61, 7.50), women with good knowledge of MCH services ( <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M4\"> <mtext>OR</mtext> <mo>=</mo> <mn>2.283</mn> </math> ; 95% CI: 1.51, 3.44), women who had a positive attitude towards MCH services ( <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M5\"> <mtext>OR</mtext> <mo>=</mo> <mn>1.69</mn> </math> ; 95% CI: 0.79, 3.6), availability of health institutions ( <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M6\"> <mtext>OR</mtext> <mo>=</mo> <mn>2.6</mn> </math> ; 95% CI: 0.95, 7.20), and women who had an ANC follow-up ( <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M7\"> <mtext>OR</mtext> <mo>=</mo> <mn>2.78</mn> </math> ; 95% CI: 2.07, 3.73) were higher institutional delivery prevalence among pastoralist women. Moreover, institutional delivery among women who were educated above the college level was more than two times ( <math xmlns=\"http://www.w3.org/1998/Math/MathML\" id=\"M8\"> <mtext>OR</mtext> <mo>=</mo> <mn>2.56</mn> </math> ; 95% CI: 1.985, 3.304) higher than among women who were not educated. Conclusion. Pastoralist women in Ethiopia were found to be a disadvantaged group for institutional delivery at national level. Husband involvement, educational level, ANC visit, knowledge and attitude for MCH service, and health facility distance were identified to have significant association with institutional delivery.","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":" 8","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135192753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Missed Opportunity of Antenatal Care Services Utilization and Associated Factors among Reproductive Age Women in Eastern Hararghe Zone, Eastern Ethiopia: Mixed Methods Study.","authors":"Ibsa Mussa,&nbsp;On Makhubela-Nkondo,&nbsp;Melat B Maruta,&nbsp;Adera Debella","doi":"10.1155/2023/8465463","DOIUrl":"10.1155/2023/8465463","url":null,"abstract":"<p><strong>Background: </strong>Despite the enormous advantages of early pregnancy-related problem diagnosis and therapy during prenatal care visits, not all pregnant women begin antenatal care at the proper time. Thus, this study aims to identify factors associated with missed opportunities for antenatal care service utilization among reproductive-age women in Eastern Ethiopia.</p><p><strong>Methods: </strong>A mixed methods study design (quantitative and qualitative) was conducted in Grawa, Meta, and Haramaya woredas from September 5 to December 5, 2019. The quantitative data were analyzed using SPSS version 25. A multivariable logistic regression analysis model was used to identify the predictors. Statistical software programs based on ATLAS.ti version 8.2 was were used to conduct the thematic analysis of the qualitative data.</p><p><strong>Results: </strong>Overall, missed opportunities for antenatal care were 15.4% of 95% (12.1, 19.1%). Factors such as maternal age being 15-24 (AOR = 6.9, 95% CI: 2.89-8.81); having a college education (AOR = 0.02, 95% CI: 0.001, 0.42), elementary (AOR = 0.05, 95% CI: 0.002, 0.98), and secondary education (AOR = 0.04, 95% CI: 0.001, 0.88); having five and more parity (AOR = 0.08, 95% CI: 0.01, 0.75); three visits (AOR = 0.10, 95% CI: 0.02, 0.71); those in the first trimester (AOR = 0.02, 95% CI: 0.001, 0.35) and the second trimester (AOR = 0.01, 95% CI: 0.001, 0.26); and get information from a health facility (AOR =0.09, 95% CI: 0.01, 0.67) and traditional birth attendance (AOR = 0.02, 95% CI: 0.001, 0.74) were factors statistically associated with outcome variables.</p><p><strong>Conclusions: </strong>According to this report, relatively high proportions of pregnant women experienced missed opportunities in antenatal care follow-up. Factors such as maternal age, education, parity, frequency, timing, and media access were statistically significantly correlated with missed antenatal care follow-up. Therefore, all stakeholders should emphasize advocating for and enhancing the benefits of antenatal care; this in turn plays a crucial role in increasing the follow-up of clients for these crucial services. Moreover, health policy implementers need to coordinate their tracking of pregnant women who missed their antenatal care session.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"8465463"},"PeriodicalIF":3.2,"publicationDate":"2023-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10555490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41160158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in Antenatal Care Visits between Urban and Rural Ethiopian Women.","authors":"Senahara Korsa Wake,&nbsp;Abera Botore,&nbsp;Ahmed Mohammed,&nbsp;Kolato Gemede,&nbsp;Moyata Bariso,&nbsp;Urge Gerema","doi":"10.1155/2023/9031344","DOIUrl":"10.1155/2023/9031344","url":null,"abstract":"<p><strong>Background: </strong>Utilizing antenatal care is one of the best ways to identify issues that are already present or could arise throughout pregnancy. Despite increased efforts to expand health services and antenatal care utilization, less is known regarding antenatal care disparities across different population segments. Therefore, the purpose of this study was to assess the degree of discrepancies between urban and rural Ethiopian pregnant women's use of antenatal care.</p><p><strong>Methods: </strong>A total sample of 3927 women who gave birth to living children between 2014 and 2019 was included in the study from the 2019 Ethiopia Mini Demographic and Health Survey. Negative binomial Poisson's regression was adopted to analyze the data.</p><p><strong>Results: </strong>The majority of pregnant women (73.8%) attend at least one antenatal care. Pregnant women in rural areas visited fewer number of antenatal care (68.36%) than those in urban areas (90.1%). Women with age range of 30-40 (IRR: 4.56, 95% CI: 1.07-19.34), women with attending incomplete primary education (IRR: 0.05, 95% CI: 0.02-0.12), women with attending complete primary education (IRR: 0.17, 95% CI: 0.07-0.42), women from middle-income households (IRR: 0.12, 95% CI: 0.06-0.24), women from richer household (IRR: 0.26, 95% CI: 0.14,0.5), women from the richest household (IRR: 0.45, 95% CI: 0.24-0.86), and pregnant women from rural areas (IRR: 0.615, 95%: 0.56-0.67) were observed to be linked with the frequency of antenatal care visits.</p><p><strong>Conclusion: </strong>In Ethiopia, three-fourths of pregnant women attend at least one antenatal care. Place of residence, educational attainment, age in five years' group, and wealth index for urban/rural were related to the frequency of antenatal care visits.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"9031344"},"PeriodicalIF":3.2,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41173328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Awareness, and Control of Hypertensive Disorders amongst Pregnant Women Seeking Healthcare in Ghana.","authors":"Pauline Boachie-Ansah,&nbsp;Berko Panyin Anto,&nbsp;Afia Frimpomaa Asare Marfo,&nbsp;Edward Tieru Dassah,&nbsp;Constance Caroline Cobbold,&nbsp;Morrison Asiamah","doi":"10.1155/2023/4194443","DOIUrl":"https://doi.org/10.1155/2023/4194443","url":null,"abstract":"<p><p>Hypertensive disorders in pregnancy (HDPs) are no longer seen as \"transitory diseases cured by delivery.\" It accounts for up to 50% of maternal deaths. Information concerning HDPs is less in developing countries like Ghana. This study was conducted to find out the prevalence, awareness, risk factors, control, and the birth outcomes of HDPs. This was a retrospective cohort study conducted among pregnant women seeking care in selected health facilities in the Ashanti Region. Data on demographics, HDPs, and its associated birth outcomes were collected. Logistic regression models were used to examine the association of the independent variables with HDPs. The burden of HDPs was 37.2% among the 500 mothers enrolled with chronic hypertension superimposed with preeclampsia accounting for 17.6%, chronic hypertension, 10.2%, and preeclampsia 6.8% whilst gestational hypertension was 2.6%. It was observed that 44% (220) of the mothers had excellent knowledge on HDPs. Oral nifedipine and methyldopa were frequently used for HDP management, and it resulted in a significant reduction in HDP burden from 37.2% to 26.6%. Factors that influenced the increased risk of HDPs were grand multigravida (AOR = 4.53; CI = 1.42-14.42), family history of hypertension (AOR = 3.61; CI = 1.89-6.90), and the consumption of herbal preparations (AOR = 2.92; CI = 1.15-7.41) and alcohol (AOR = 4.10; CI = 1.34-12.62) during pregnancy. HDPs increased the risk of preterm delivery (AOR = 2.66; CI = 1.29-5.89), stillbirth (AOR = 12.47; CI = 2.72-57.24), and undergoing caesarean section (AOR = 1.70; CI = 1.10-2.61) amongst mothers during delivery. The burden of HDPs is high amongst pregnant mothers seeking care in selected facilities. There is the need for intensified campaign on HDPs in the Ashanti Region of Ghana.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"4194443"},"PeriodicalIF":3.2,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10508994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41120023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Four Intrapartum Cardiotocography Classifications for Predicting Neonatal Acidemia at Birth.","authors":"Nika Troha, Katja Razem, Ursa Luzovec, Miha Lucovnik","doi":"10.1155/2023/5853889","DOIUrl":"10.1155/2023/5853889","url":null,"abstract":"<p><strong>Objective: </strong>To compare diagnostic values of four intrapartum cardiotocography (CTG) classifications in predicting neonatal acidemia at birth.</p><p><strong>Methods: </strong>Retrospective case-control study. Forty-three CTG traces with an umbilical artery pH < 7.00 (study group) and 43 traces with a pH ≥ 7.00 (control group) were analyzed. Inclusion criteria were singleton pregnancy, cephalic presentation, admission to labour ward during active phase of first stage of labour, and gestational age 37⁺⁰ to 41⁺⁶ weeks. Exclusion criteria were suspected intrauterine growth restriction, oligohydramnios, polyhydramnios, pregestational or gestational insulin-dependent diabetes mellitus, and preeclampsia. Last 30-60 minutes before delivery of CTG traces was classified retrospectively according to four classification systems-International Federation of Gynecology and Obstetrics (FIGO), Royal College of Obstetricians and Gynaecologists (RCOG), National Institute of Child Health and Human Development (NICHD), and the 5-tier system by Parer and Ikeda. Predictive value of each classification for neonatal acidemia was assessed using receiver operating characteristics (ROC) analysis.</p><p><strong>Results: </strong>FIGO, RCOG, and NICHD classifications predicted neonatal acidemia with areas under the ROC curves (AUC) of 0.73, 95% confidence interval (CI) 0.63-0.84; 0.72, 95% CI 0.60-0.83; and 0.69, 95% CI 0.57-0.80, respectively. The five-tier system by Parer and Ikeda had significantly better predictive value with an AUC of 0.96, 95% CI 0.91-1.00.</p><p><strong>Conclusions: </strong>The 5-tier classification system proposed by Parer and Ikeda for assessing CTG in labour was superior to FIGO, RCOG, and NICHD intrapartum CTG classifications in predicting severe neonatal acidemia at birth.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"5853889"},"PeriodicalIF":3.2,"publicationDate":"2023-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9940944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10764643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Knowledge about Obstetric Danger Signs and Associated Factors among Pregnant Women in Debre Tabor Town, Northwest Ethiopia.","authors":"Mestawut Mihret,&nbsp;Hailegebriel Wondimu","doi":"10.1155/2023/1475500","DOIUrl":"https://doi.org/10.1155/2023/1475500","url":null,"abstract":"<p><strong>Background: </strong>World Health Organization estimates that 800 women die from pregnancy or childbirth-related complications around the world every day. With the assumption that \"every pregnancy faces risk\" women should be aware of the danger signs of obstetric complications during pregnancy, delivery, and postpartum. Indications on the prevalence of obstetric danger signs and risk factors were crucial in designing programs at different levels in reducing maternal morbidity and mortality.</p><p><strong>Objective: </strong>To assess the knowledge about obstetric danger signs and associated factors among pregnant women in Debre Tabor town, Northwest Ethiopia, 2021.</p><p><strong>Methods: </strong>A community-based cross-sectional study was conducted with 295 respondents to assess knowledge about obstetrical danger signs among pregnant women in Debre Tabor town from July to September 2021. Data were collected through self-administered questionnaires. Proportional followed by simple random sampling was used to select the study participants among the pregnant women in each of the six kebeles of the town. Adjusted odds ratios at 95% confidence interval and a value of <i>p</i> < 0.05 were used to identify the predictors.</p><p><strong>Results: </strong>From a total of 295 interviewed, 61% of them were poorly knowledgeable about obstetric danger signs, but 39% of them were knowledgeable. According to our study, maternal age less than or equal to 30 years (adjusted odds ratio = 5.44; 95% confidence interval: 3.26,9.10), no formal education (adjusted odds ratio = 9.488; 95% confidence interval: 4.73, 13.14), one-time gravidity (adjusted odds ratio = 7.81; 95% confidence interval: 4.79, 9.19), and frequency of antenatal follow-up less than 4 times (adjusted odds ratio = 4.10; 95% confidence interval: 1.88, 8.96) were factors which significantly associated with the poor knowledge of obstetric danger signs.</p><p><strong>Conclusion: </strong>As the knowledge of pregnant women towards obstetric danger signs was low, maternal age less than or equal to 30 years, no formal education, one-time gravidity, and less than 4 times the frequency of antenatal follow-up are associated factors for poor knowledge on obstetric danger signs.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"1475500"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019974/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9144031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnitude, Associated Risk Factors, and Trend Comparisons of Urinary Tract Infection among Pregnant Women and Diabetic Patients: A Systematic Review and Meta-Analysis.","authors":"Abayeneh Girma,&nbsp;Aleka Aemiro,&nbsp;Dereba Workineh,&nbsp;Dessalew Tamir","doi":"10.1155/2023/8365867","DOIUrl":"https://doi.org/10.1155/2023/8365867","url":null,"abstract":"<p><p>Urinary tract infection (UTI) remains the most common bacterial infection that affects millions of people around the world, especially pregnant women (PW) and people with diabetes mellitus (DM). This systematic review and meta-analysis was aimed at finding the pooled prevalence of UTI and its associated risk factors among PW and DM patients. Scientific articles written in English were recovered from PubMed, ScienceDirect, Web of Science, Google Scholar, Cochrane Library, Google Engine, and University Library Databases. \"Prevalence,\" \"urinary tract infection,\" \"associated factors,\" \"pregnant women,\" \"diabetic patients,\" and \"Ethiopia\" were search terms used for this study. For critical appraisal, PRISMA-2009 was applied. Heterogeneity and publication bias were evaluated using Cochran's <i>Q</i>, inverse variance (<i>I</i>²), and funnel plot asymmetry tests. A random effect model was used to calculate the pooled prevalence of UTI and its associated factors among both patients, along with the parallel odds ratio (OR) and 95% confidence interval (CI). For this meta-analysis, a total of 7271 participants were included in the 25 eligible studies. The pooled prevalence of UTI in Ethiopia among both patients was 14.50% (95% CI: 13.02, 15.97), of which 14.21% (95% CI: 12.18, 16.25) and 14.75% (95% CI: 12.58, 16.92) were cases of DM and PW, respectively. According to the subgroup analysis, the highest prevalence was observed in the Oromia region (19.84%) and in studies conducted from 2018 to 2022 (14.68%). Being female (AOR: 0.88, and 95% CI: 0.11, 1.65, <i>P</i> = 0.01) and having an income level ≤ 500ETB (AOR: 4.46, and 95% CI: -1.19, 10.12, <i>P</i> = 0.03) were risk factors significantly associated with UTI among patients with DM and PW, respectively. Furthermore, a history of catheterization (AOR = 5.58 and 95% CI: 1.35, 9.81, <i>P</i> < 0.01), urinary tract infection (AOR: 3.52, and 95% CI: 1.96, 5.08, <i>P</i> < 0.01), and symptomatic patients (AOR: 2.32, and 95% CI: 0.57, 4.06, <i>P</i> < 0.01) were significantly associated with UTI in both patients. Early diagnosis and appropriate medication are necessary for the treatment of UTI in patients with DM and PW.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"8365867"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10403334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9952076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal Third Delay and Associated Factors among Women Admitted for Emergency Obstetric Care in Public Hospitals in Sidama Regional State, Ethiopia.","authors":"Esuyawkal Mislu,&nbsp;Ali Seid,&nbsp;Nigus Bililign,&nbsp;Terefe Woyo,&nbsp;Dubale Dulla","doi":"10.1155/2023/7767208","DOIUrl":"https://doi.org/10.1155/2023/7767208","url":null,"abstract":"<p><strong>Background: </strong>Timing to get obstetric care is critical in preventing maternal death and disability. Maternal third delay, the delay in receiving care after reaching health facilities, involves factors related to organization, quality of care, patient referral, and availability of staff and equipment. However, data is limited on maternal third delay and its associated factors at higher health facilities in Ethiopia.</p><p><strong>Objective: </strong>This study is aimed at assessing the magnitude of maternal third delay and associated factors among women admitted for emergency obstetric care in public hospitals in Sidama Regional State, Ethiopia, 2021.</p><p><strong>Methods: </strong>An institution-based cross-sectional study was conducted from September to November 2021. Face-to-face interview with a structured questionnaire and data extraction from medical charts were carried out in selected 542 women (using systematic sampling method). The collected data were coded and entered using EpiData, and bivariable and multivariable logistic regression analyses were done using SPSS version 25. Statistical significances were declared at <i>p</i> value less than 0.05.</p><p><strong>Results: </strong>Maternal third delay was identified among 29.3% (95%CI = 25.2 - 33.5) of the respondents. Additionally, women who arrived with a referral from other health facilities (AOR = 0.311, 95%CI = 0.181 - 0.534), well prepared for birth and its complications (AOR = 2.418, 95%CI = 1.51 - 3.869), self-employed (AOR = 0.223, 95%CI = 0.122 - 0.409), being a government employee (AOR = 0.157, 95%CI = 0.063 - 0.396), having ANC follow-up (AOR = 2.795, 95%CI = 1.318 - 5.928), and absence of health professional (AOR = 4.63, 95%CI = 2.857 - 7.50) were significantly associated with maternal third delay.</p><p><strong>Conclusion: </strong>This study identified that maternal third delay was high, which indicates that women have not received emergency obstetric care in the recommended time range after they arrived at the health facilities.</p>","PeriodicalId":47062,"journal":{"name":"Journal of Pregnancy","volume":"2023 ","pages":"7767208"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10118880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9388660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}