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Research on Customer Satisfaction of Yongheng Wanxing Hotel Based on Customer Value Theory 基于顾客价值理论的永恒万兴酒店顾客满意度研究
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0101003
Chen Wenjie, Xia Ying, Li Ludan
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引用次数: 0
Customer Satisfaction Measurement Index and Methods of Midscale Hotels Based on OTA Online Reviews 基于OTA在线评论的中档酒店顾客满意度测评指标与方法
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0101004
S. Yiwen, Zou Guangyong
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引用次数: 0
Development Strategies for the Industry of Tourism Characteristic Small Town in Guangxi 广西旅游特色小镇产业发展策略
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0101005
Chen Wenjie, Yang Xiaoru
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引用次数: 0
Research on the new media marketing process of Beijing traffic policy 北京交通政策新媒体营销过程研究
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0101002
Wang Xueqing, Wang Junxia
{"title":"Research on the new media marketing process of Beijing traffic policy","authors":"Wang Xueqing, Wang Junxia","doi":"10.35534/fm.0101002","DOIUrl":"https://doi.org/10.35534/fm.0101002","url":null,"abstract":"","PeriodicalId":46093,"journal":{"name":"Frontiers of Engineering Management","volume":"256 1","pages":""},"PeriodicalIF":7.4,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76782823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on the Current Situation of Budget Management of Social Insurance Fund 社会保险基金预算管理现状研究
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0102012c
L. Bin, Gao Yi
{"title":"Research on the Current Situation of Budget Management of Social Insurance Fund","authors":"L. Bin, Gao Yi","doi":"10.35534/fm.0102012c","DOIUrl":"https://doi.org/10.35534/fm.0102012c","url":null,"abstract":"","PeriodicalId":46093,"journal":{"name":"Frontiers of Engineering Management","volume":"12 1","pages":""},"PeriodicalIF":7.4,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84695699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Government Subsidy really enhance the Green Performance of Manufacturing Enterprise? 政府补贴真的能提高制造企业的绿色绩效吗?
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0101001
Yang Dong, Shi Huibin
{"title":"Does Government Subsidy really enhance the Green Performance of Manufacturing Enterprise?","authors":"Yang Dong, Shi Huibin","doi":"10.35534/fm.0101001","DOIUrl":"https://doi.org/10.35534/fm.0101001","url":null,"abstract":"","PeriodicalId":46093,"journal":{"name":"Frontiers of Engineering Management","volume":"33 1","pages":""},"PeriodicalIF":7.4,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76497985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Unification of ‘Innate’ and ‘Acquired’: Progress in the Study of Executive Characteristics “先天”与“后天”的统一:执行特征研究进展
IF 7.4 2区 工程技术
Frontiers of Engineering Management Pub Date : 2019-01-01 DOI: 10.35534/fm.0102006
Wang Fule
{"title":"Unification of ‘Innate’ and ‘Acquired’: Progress in the Study of Executive Characteristics","authors":"Wang Fule","doi":"10.35534/fm.0102006","DOIUrl":"https://doi.org/10.35534/fm.0102006","url":null,"abstract":"","PeriodicalId":46093,"journal":{"name":"Frontiers of Engineering Management","volume":"31 1","pages":""},"PeriodicalIF":7.4,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88519821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma. 作为恶性胸膜间皮瘤潜在治疗靶点的 SORIN 和 PLK1。
IF 5.2 2区 工程技术
Frontiers of Engineering Management Pub Date : 2016-12-01 Epub Date: 2016-11-10 DOI: 10.3892/ijo.2016.3765
Tatsuya Kato, Daiyoon Lee, Licun Wu, Priya Patel, Ahn Jin Young, Hironobu Wada, Hsin-Pei Hu, Hideki Ujiie, Mitsuhito Kaji, Satoshi Kano, Shinichi Matsuge, Hiromitsu Domen, Hiromi Kanno, Yutaka Hatanaka, Kanako C Hatanaka, Kichizo Kaga, Yoshiro Matsui, Yoshihiro Matsuno, Marc De Perrot, Kazuhiro Yasufuku
{"title":"SORORIN and PLK1 as potential therapeutic targets in malignant pleural mesothelioma.","authors":"Tatsuya Kato, Daiyoon Lee, Licun Wu, Priya Patel, Ahn Jin Young, Hironobu Wada, Hsin-Pei Hu, Hideki Ujiie, Mitsuhito Kaji, Satoshi Kano, Shinichi Matsuge, Hiromitsu Domen, Hiromi Kanno, Yutaka Hatanaka, Kanako C Hatanaka, Kichizo Kaga, Yoshiro Matsui, Yoshihiro Matsuno, Marc De Perrot, Kazuhiro Yasufuku","doi":"10.3892/ijo.2016.3765","DOIUrl":"10.3892/ijo.2016.3765","url":null,"abstract":"<p><p>Malignant pleural mesothelioma (MPM) is an aggressive type of cancer of the thoracic cavity commonly associated with asbestos exposure and a high mortality rate. There is a need for new molecular targets for the development of more effective therapies for MPM. Using quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) and an RNA interference-based screening, we examined the SORORIN gene as potential therapeutic targets for MPM in addition to the PLK1 gene, which is known for kinase of SORORIN. Following in vitro investigation of the effects of target silencing on MPM cells, cell cycle analyses were performed. SORORIN expression was analyzed immunohistochemically using a total of 53 MPM samples on tissue microarray. SORORIN was found to be overexpressed in the majority of clinical MPM samples and human MPM cell lines as determined by qRT-PCR. Gene suppression of each SORORIN and PLK1 led to growth inhibition in MPM cell lines. Knockdown of SORORIN showed an increased number of G2M-phase population and a larger nuclear size, suggesting mitotic arrest. High expression of SORORIN (SORORIN-H) was found in 50.9% of all the MPM cases, and there is a tendency towards poorer prognosis for the SORORIN-H group but the difference is not significant. Suppression of SORORIN with PLK1 inhibitor BI 6727 showed a combinational growth suppressive effect on MPM cell growth. Given high-dose PLK1 inhibitor induced drug-related adverse effects in several clinical trials, our results suggest inhibition SORORIN-PLK1 axis may hold promise for the treatment of MPMs.</p>","PeriodicalId":46093,"journal":{"name":"Frontiers of Engineering Management","volume":"4 1","pages":"2411-2420"},"PeriodicalIF":5.2,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3892/ijo.2016.3765","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70159508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
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