Revista Chilena de Pediatria-Chile最新文献_第9页

Effect of vitamin D supplementation as a single dose on the nutritional status of vitamin D. 单剂量补充维生素D对维生素D营养状况的影响。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.1402

Johanna Pacheco-Acosta, Fernando Pizarro

{"title":"Effect of vitamin D supplementation as a single dose on the nutritional status of vitamin D.","authors":"Johanna Pacheco-Acosta, Fernando Pizarro","doi":"10.32641/rchped.vi91i5.1402","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.1402","url":null,"abstract":"Introduction: Infants are a group at risk of vitamin D (VD) deficiency. The administration of 400 IU of VD per day during the first year of life does not achieve 100% adherence. A single dose of 100,000 IU of oral VD is safe in newborns.Objective: To compare the effect of oral administration of VD between a single dose of 100,000 IU at one month of age vs daily doses of 400 IU on serum concentrations of VD, at 6 months of age.Subjects and method: Randomized clinical trial, without masking. 84 healthy infants were included at 1 month of age, randomized to the study group (SG) receiving a single oral dose of 100,000 IU or to the control group (CG), who received daily oral doses of VD of 400 IU from the 1st to the 6th month of life. At 6 months of life, the serum concentration of VD was determined.Results: 65 infants completed the study, 36 in SG and 29 in CG. No VD deficiency was found. VD insufficient was 5.5% and 6.8% in the SG and CG, respectively. The serum concentration of VD at six months of age was 38.8 ± 5.2 ng/ml and 39.7 ± 6.3 ng/ml for the SG and CG, respectively (NS).Conclusions: Supplementation of 100,000 IU of VD at one month age achieves serum concentrations of VD at 6 months of life similar to the administration of daily doses of 400 IU of VD from the 1st to the 6th month.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"684-690"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38781971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[When breast milk is a way of pathogens]. [当母乳是病原体的一种方式]。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.3079

Patricia Mena Nannig

引用次数: 0

Assessment of knowledge and autonomy for the transition from adolescent toward adult care. 从青少年到成人护理过渡的知识和自主性评估。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.1519

Francisco Funes D, Francisca León L, Romina Valenzuela C

{"title":"Assessment of knowledge and autonomy for the transition from adolescent toward adult care.","authors":"Francisco Funes D, Francisca León L, Romina Valenzuela C","doi":"10.32641/rchped.vi91i5.1519","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.1519","url":null,"abstract":"Introduction: In the last decades more and more children survive with complex health conditions, requiring a transition from pediatric to adult care. It is essential to have instruments that provide information on the level of preparation of patients for this process.Objective: To create and validate a questionnaire to measure the readiness status of adolescent patients with chronic diseases in the transition process.Patients and method: Based on international questionnaires, a self-report instrument was designed which was subjected to content validity by experts, and then to comprehension and feasibility tests in a pilot group. Subsequently, construct and reliability validation were performed through a factorial analysis after applied it to adolescents living with a chronic illness.Results: After the analysis made by 11 experts and the pilot group with 8 patients, we obtained an instrument that was fully answered by 168 teenagers (Average age 14.4 years). After construct validation, a 24-items instrument of high clinical relevance was developed, with 9 items with acceptable psychometric properties, which were highlighted in the final questionnaire.Conclusion: a self-report instrument aimed to measure the readiness of adolescents during the transition process to adult care is presented. The reported psycho metric properties of the instrument were insufficient to consider it validated since the construct vali dity and reliability were only checked for 9 of the 24 items.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"722-731"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38781978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[The responsible use and dissemination of information in a pandemic: an ethical imperative]. [在大流行病中负责任地使用和传播信息:道德责任]。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.2420

Blanca Bórquez P, M Ximena Luengo-Charath, Verónica Anguita M, M Luz Bascuñán R, Isabel M Pacheco M, Patricio Michaud Ch, Ricardo Vacarezza Y

{"title":"[The responsible use and dissemination of information in a pandemic: an ethical imperative].","authors":"Blanca Bórquez P, M Ximena Luengo-Charath, Verónica Anguita M, M Luz Bascuñán R, Isabel M Pacheco M, Patricio Michaud Ch, Ricardo Vacarezza Y","doi":"10.32641/rchped.vi91i5.2420","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.2420","url":null,"abstract":"The current COVID-19 pandemic is producing an unprecedented impact in the different spheres of life, at the same time that it has highlighted the importance that the Bioethics discipline has in analyzing and deliberating of emerging ethical challenges, before making reasonable and prudent decisions. The management and communication of information on this crisis has not been properly addressed, where it is considered that its negative effects may lead not only to interfere with the communication channels with citizens but also affect the expected adherence of the population to the indications that they need to follow. This issue is especially complex when experiencing a period of information explosion, a phenomenon called 'infodemic' by the World Health Organization. This article, claiming the ethical and legal imperative to act responsibly in collecting, using, and disse minating the information that helps any authority that plays a social function, proposes a series of recommendations to achieve its effectiveness in practice.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"794-799"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39118037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Congenital anomalies and comorbidities in neonates with Down Syndrome. 唐氏综合征新生儿的先天性异常和合并症。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.1518

Nicole Nakousi Capurro, Carolina Cares Basualto, Angélica Alegría Olivos, Marina Gaínza Lein, Luis López Aristizabal, Alejandro Gayan Torrente, Valentina Ojeda Contreras, María José Irarrázaval Montero

{"title":"Congenital anomalies and comorbidities in neonates with Down Syndrome.","authors":"Nicole Nakousi Capurro, Carolina Cares Basualto, Angélica Alegría Olivos, Marina Gaínza Lein, Luis López Aristizabal, Alejandro Gayan Torrente, Valentina Ojeda Contreras, María José Irarrázaval Montero","doi":"10.32641/rchped.vi91i5.1518","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.1518","url":null,"abstract":"Introduction: In Chile, Down syndrome has a prevalence of 2.5 in 1,000 live births. These patients present more congenital anomalies and comorbidities than the general population, increasing their hospitaliza tion rate.Objective: To describe congenital anomalies and comorbidities of neonates with Down syndrome born and/or hospitalized between 2008 and 2018.Patients and method: We conducted a retrospective review of patient's medical records born and/or hospitalized during their first 28 days of life between January 1st, 2008, and December 31st, 2018. For each patient, we recorded maternal age, familiar cases of Down Syndrome, pre and perinatal history, genetic study result, as well as age at admission, reason for hospitalization, comorbidities, length of stay, and death. Two patients that had more than 50% of incomplete medical records were excluded. We studied the associations between comorbidities, congenital anomalies, and death.Results: 140 in 79,506 newborns (0.2%) were diagnosed at our center with Down Syndrome in their neonatal period. 24.7% were born preterm and 26.4% had low birth weight for gestational age. Morbidities and hospitalizations were present in 83.6% and 90%, of the study population, respectively. The main reason for hospitalization was polycythemia and the most frequent was hyperbilirubinemia. Four patients died (2.9%) and 70.7% presented at least one congenital anomaly, mainly heart disease. Median maternal age was 36 years and 57.1% of mothers were aged 35 or older.Conclusions: This cohort of patients with Down Syndrome provides important information for the optimization of their perinatal management and follow-up.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"732-742"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38781979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Pathogenic variant in the PCDH19 gene in a patient with epilepsy and cognitive disability. 癫痫和认知障碍患者的PCDH19基因致病性变异

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.1490

Viviana Venegas Silva, Elisa García Venegas, M Gabriela Repetto Lisboa, Eva Barroso Ramos, Pablo Lapunzina Badia

{"title":"Pathogenic variant in the PCDH19 gene in a patient with epilepsy and cognitive disability.","authors":"Viviana Venegas Silva, Elisa García Venegas, M Gabriela Repetto Lisboa, Eva Barroso Ramos, Pablo Lapunzina Badia","doi":"10.32641/rchped.vi91i5.1490","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.1490","url":null,"abstract":"Introduction: The association of family cases of epilepsy and intellectual disability in women was reported in 1971. In 2008, the role of pathogenic variants of the PCDH19 gene in some families were identified. The disease presents with febrile seizure clusters, intellectual disability, and autistic features. Most cases are due to de novo variants, however, there are some inherited cases, with an atypical way of X-linked transmission.Objective: To report the case of a patient with epilepsy carrier of a pathogenic variant of the PCDH19 gene, reviewing the natural history of this condition and the available evidence for its management.Clinical case: Female patient, with normal history of pregnancy and perinatal period. At 6 months, while febrile, she presented focal motor seizure clusters that repeated at 14, 18, 21 months and 3 years old, always associated with fever, even presenting status epilepticus. She is on therapy with topiramate and valproic acid, achieving 13 seizure-free years. The analysis of the SCN1A gene showed no abnormalities and the study of the PCDH19 gene revealed a de novo heterozygous pathogenic variant. The patient evolved with intellectual disability and severe behavioral disorders that require mental health team support.Conclusions: PCDH19 pathogenic variants have varied phenotypic expression. The genetic diagnosis should be guided with the clinical features. Long-term psychiatric morbidity can be disabling.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"761-766"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39118033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Construction and validation of an instrument to measure knowledge of mothers and caregivers on complementary feeding of infants. 构建和验证一种测量母亲和照顾者对婴儿补充喂养知识的工具。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.1078

Marco Sierra-Zúñiga, Claudia Holguin Betancourt, Andry Yasmid Mera-Mamián, Mario Delgado-Noguera, José Andrés Calvache

{"title":"Construction and validation of an instrument to measure knowledge of mothers and caregivers on complementary feeding of infants.","authors":"Marco Sierra-Zúñiga, Claudia Holguin Betancourt, Andry Yasmid Mera-Mamián, Mario Delgado-Noguera, José Andrés Calvache","doi":"10.32641/rchped.vi91i5.1078","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.1078","url":null,"abstract":"Introduction: Adequate nutrition during the first two years of life is crucial for the full development of human potential. Inadequate, early, or late introduction of complementary feeding has consequences in the short- and long-term. Complementary feeding depends largely on the knowledge of the caregiver who, in Latin American countries, is usually the mother.Objective: To create and validate an ins trument to measure knowledge about complementary feeding.Subjects and method: Observational study in which 80 community mothers and 12 expert pediatricians participated. It was carried out in two stages, the creation of the instrument (following the 7 phases proposed by Sampieri) and the va lidation through the evaluation of the apparent validity, construct and content validity, internal con sistency, and intra-observer reliability.Results: A self-administered instrument was created that ini tially included 14 questions about maternal and caregiver's knowledge. During the validation of the construct, 3 domains were identified and four questions were eliminated. In the content validation, 10 questions of the final instrument scored higher than 9 (on a scale of 0-10) in the characteristics of quality, vocabulary, relevance, and topicality. The global internal consistency of the instrument was moderate (Cronbach's alpha: 0.64) and the intra-observer reliability was acceptable (k: 0.21-0.40) for 80% of its items.Conclusions: the first self-administered instrument validated in the region to measure the knowledge of mothers and caregivers about complementary feeding is presented. It will allow to design and develop strategies in relation to maternal and caregiver's knowledge of comple mentary feeding.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"711-721"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38781977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Eating disorders in adolescents: role of the pediatrician. Recommendations of the Adolescence Branch of the Chilean Society of Pediatrics. 青少年饮食失调:儿科医生的角色。智利儿科学会青少年分会的建议。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.1537

Verónica Gaete P, Carolina López C

引用次数: 0

Vegetarian diets in first year university students. 大学一年级学生的素食。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.2143

Javiera Aravena, Tamara Zubarew, Paula Bedregal, Soledad Zuzulich, Pascuala Urrejola

{"title":"Vegetarian diets in first year university students.","authors":"Javiera Aravena, Tamara Zubarew, Paula Bedregal, Soledad Zuzulich, Pascuala Urrejola","doi":"10.32641/rchped.vi91i5.2143","DOIUrl":"https://doi.org/10.32641/rchped.vi91i5.2143","url":null,"abstract":"INTRODUCTION There has been an increase in the popularity of vegetarian diets, especially among adolescents and young adults. These diets seem to be healthy and balanced, but the recommendations are contro versial regarding potential nutritional deficits. OBJECTIVE To identify the frequency and types of ve getarian diet used, their motivation, and sources of information. PATIENTS AND METHOD Cross-sec tional analytical study in freshmen students from the Pontifical Catholic University of Chile (PUC). Through an online survey, we collected demographic information and diet characterization of those who considered themselves as vegetarians. Variables were analyzed using IDM SPSS Statistics® soft ware and in Excel® spreadsheet in a quantitative way. RESULTS 152 students answered the survey (15.2% of the sample) and, out of these, 49.4% were vegetarian. 32.4% started this eating pattern bet ween the ages 12 and 18 and among their most frequent motivations were environmentalists (91.9%) and animalists (72.9%). 52.9% of vegetarians take vitamin B 12 supplementation but only 15.9% reported having this deficiency. 75.7% obtain information related to vegetarian diets through digital media. CONCLUSION In the surveys answered, we found a high percentage of vegetarian students, the refore, health professionals need to be trained in this area to assure adequate nutritional education, supplementation if necessary, and follow-up.","PeriodicalId":46023,"journal":{"name":"Revista Chilena de Pediatria-Chile","volume":"91 5","pages":"705-710"},"PeriodicalIF":0.0,"publicationDate":"2020-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38781975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

[Adolescents whit epilepsy in transition to adult medical care]. [青少年癫痫过渡到成人医疗护理]。

Revista Chilena de Pediatria-Chile Pub Date : 2020-10-01 DOI: 10.32641/rchped.vi91i5.2949

Daniela Franco, Ángela Mora, Gloria Muñoz, Carolina Heresi

引用次数: 0