{"title":"Hyponatremia Induced by Duloxetine: A Case Report.","authors":"Daniel Hu, Sarah Wurster","doi":"10.4140/TCP.n.2018.446","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.446","url":null,"abstract":"<p><strong>Purpose: </strong>There are a limited number of case reports in the literature which describe hyponatremia/syndrome of inappropriate antidiuretic hormone (SIADH) induced by duloxetine.</p><p><strong>Summary: </strong>This case report adds to the literature by describing a patient who developed hyponatremia/SIADH after two doses of duloxetine.</p><p><strong>Conclusion: </strong>Hyponatremia/SIADH can develop rapidly after initiation of duloxetine. Clinicians should be aware of the potential for this adverse drug reaction, particularly in elderly females.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"446-449"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.446","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How Are We Doing? Mid-Year Checkup.","authors":"Paul Baldwin","doi":"10.4140/TCP.n.2018.468","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.468","url":null,"abstract":"","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"468"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.468","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of Cranberry Use for Preventing Urinary Tract Infections in Older Adults.","authors":"Tiana Luczak, Michael Swanoski","doi":"10.4140/TCP.n.2018.450","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.450","url":null,"abstract":"<p><p>Urinary tract infections (UTIs) are one the of the most common types of infections in adults older than 65 years of age. Preventing UTIs with prophylactic antibiotics increases the risk of side effects and microbial resistance, and is costly. Cranberry fruit and juices contain the compound proanthrocyanidins (PACs), specifically proanthrocyanidin-A, which exerts antiadhesion characteristics against bacteria. Cranberry products therefore have been an attractive, nonantibiotic preventative option for UTIs; however, the current literature supporting cranberry use in older adults is controversial. This could be multifactorial owing to the heterogeneity of the older population as well as inconsistencies in the recommended dose of PAC in the current literature. Evidence supports that cranberry may be beneficial in preventing UTIs in specific populations such as catheterassociated UTI and postradiotherapy prostate cancer. The cost of daily capsules versus the cost of preventing a UTI in older adults is an important consideration for initiating therapy.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"450-453"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.450","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leisa L Marshall, Renée L Hayslett, Gregg A Stevens
{"title":"Therapy for Open-Angle Glaucoma.","authors":"Leisa L Marshall, Renée L Hayslett, Gregg A Stevens","doi":"10.4140/TCP.n.2018.432","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.432","url":null,"abstract":"<p><strong>Objective: </strong>Review the clinical manifestations and treatment of primary open-angle glaucoma (POAG).</p><p><strong>Data sources: </strong>Articles indexed in PubMed, Scopus, and Cochrane Library in the last 10 years using the key words \"glaucoma,\" \"open-angle glaucoma,\" and \"'open-angle glaucoma' AND 'treatment.'\" Primary sources were used to locate additional resources. ClinicalTrials. gov was used to locate unpublished studies.</p><p><strong>Study selection and data extraction: </strong>Eighty-one publications were reviewed and criteria supporting the primary objective were used to identify useful resources.</p><p><strong>Data synthesis: </strong>The literature included practice guidelines, review articles, original research articles, and product prescribing information for POAG.</p><p><strong>Conclusion: </strong>The POAG optic neuropathies result in optic disk damage and visual field loss. Ophthalmic medication therapy retards glaucoma progression, but many older patients require multiple medications to preserve vision and quality of life. An agent from the ophthalmic prostaglandin analog class is used as initial therapy in current practice because of the convenience of once-a-day administration and lower incidence of systemic side effects and slightly increased efficacy compared with other available ophthalmic medication classes. The other ophthalmic medication classes used in clinical practice include the beta-adrenergic blocking agents, the alpha-2 adrenergic agonists, and the carbonic anhydrase inhibitors. Proper ophthalmic eye-drop administration and medication adherence are imperative for preserving vision in POAG. Selective laser trabeculoplasty is a viable alternative to ophthalmic medications either initially or if a patient experiences ocular or systemic side effects from medication therapy. A modified prostaglandin analog was approved by the Food and Drug Administration in November 2017; its role in clinical practice is still evolving.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"432-445"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.432","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pharmacists Focus on Adapting for the Future.","authors":"Joanne Kaldy","doi":"10.4140/TCP.n.2018.414","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.414","url":null,"abstract":"<p><p>A wide range of changes are in the future for health care: value-based reimbursement, delivery of integrated services, the continued breakdown of silos, and interoperability maximizing communication/information exchange. The American Society of Consultant Pharmacists recently held a conference focusing on key innovations in post-acute/long-term/senior care and how pharmacists can function successfully in this new paradigm in ways that promote quality medication management, address polypharmacy, improve patients' quality of life, reduce costs, and eliminate avoidable readmissions.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"414-421"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.414","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Communicating for Drug Safety.","authors":"H Edward Davidson","doi":"10.4140/TCP.n.2018.406","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.406","url":null,"abstract":"","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"406-408"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incidence and Preventability of Medication Errors and ADEs in Ambulatory Care Older Patients.","authors":"Shirley H Díaz Hernández, Iadelisse Cruz-Gonzalez","doi":"10.4140/TCP.n.2018.454","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.454","url":null,"abstract":"<p><strong>Objective: </strong>To assess the incidence of medication errors, adverse drug events (ADEs), and potential ADEs (poADEs) in patients 65 years of age and older.</p><p><strong>Design: </strong>This is a retrospective cohort study (2011 to 2014).</p><p><strong>Setting: </strong>The study was performed at a section 330 federally funded ambulatory health care center.</p><p><strong>Patients: </strong>The study was a convenience sample selected in a nonrandomized way from event reports filed in those years.</p><p><strong>Intervention: </strong>Data were collected through event reports and medical record review. Descriptive statistics and chi-square were employed to analyze data.</p><p><strong>Results: </strong>During the study period, at least one medication error, poADE, or ADE report was documented in 170 out of 2,218 older patients (incidence: 12.5, 9.4, and 5.0 per 100 patient-years, respectively); 42.9% of ADEs were preventable. The chronic conditions most frequently related to ADEs were diabetes (18%), hypertension (18%), and hyperlipidemia (12%). The use of hypoglycemic agents was commonly associated with ADEs (14%; P = 0.001). An increased number of prescribed medications were significantly associated with all the adverse events.</p><p><strong>Conclusions: </strong>Medication errors, poADEs, and ADEs are common in patients 65 years of age or older taking more than three medications. Almost half of the detected ADEs were preventable.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 8","pages":"454-466"},"PeriodicalIF":0.0,"publicationDate":"2018-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.454","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36364544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jennifer Pruskowski, Barbara J Zarowitz, Steven M Handler
{"title":"Perceptions of Nursing Facility Providers on the Utility of Deprescribing.","authors":"Jennifer Pruskowski, Barbara J Zarowitz, Steven M Handler","doi":"10.4140/TCP.n.2018.386","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.386","url":null,"abstract":"<p><strong>Objective: </strong>Potentially inappropriate medications carry significant burden and costs to nursing facility residents and health systems. The goal of this study was to survey nursing facility providers from across the United States to describe the current utilization of deprescribing, and perceptions and desired components of a deprescribing program, in nursing facilities to reduce potentially inappropriate medications.</p><p><strong>Design/setting/participants/measurement: </strong>We surveyed health care providers who attended the 2017 AMDA-The Society for Post-Acute and Long-Term Care Medicine Annual Conference-in Phoenix, Arizona. Returned surveys were entered into an electronic database from paper copies. Survey responses were summarized using descriptive statistics.</p><p><strong>Results: </strong>Of the 1,431 conference attendees, 637 surveys were returned for a 45% response rate. Most respondents were physicians (n = 563, 88%). Respondents indicated a strong agreement with the potential for deprescribing to reduce cost to residents and nursing administration time and burden, while disagreeing that deprescribing may be depersonalizing. Respondents indicated clear preference for deprescribing programs to target medications that are no longer indicated and are \"high risk,\" and that such programs should include discussions with the resident. Respondents also agreed that deprescribing programs are successful if the resident, or the resident's family and/or caregivers, reports an improvement in quality of life.</p><p><strong>Conclusion: </strong>Among respondents there was a high degree of confidence in the potential impact of deprescribing initiatives, as well as a broad consensus of desired components. This information may increase consultant pharmacist engagement and drive future proactive deprescribing initiatives.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 7","pages":"386-402"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.386","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36304771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interventions to Improve Medication Adherence in Older Adults With Cognitive Impairment.","authors":"Soyoung Park, Zachary A Marcum","doi":"10.4140/TCP.n.2018.382","DOIUrl":"https://doi.org/10.4140/TCP.n.2018.382","url":null,"abstract":"<p><p>Many older adults experience some degree of cognitive impairment, an important risk factor for medication nonadherence. To prevent negative health outcomes secondary to medication nonadherence, identifying interventions that improve medication adherence for older adults with cognitive impairment is crucial. Other barriers to medication adherence include the structure of the health care system as well as socioeconomic and therapyrelated obstacles. The use of pharmacist-led and population-level interventions hold promise for providing optimal medication adherence for older adults with cognitive impairment.</p>","PeriodicalId":45985,"journal":{"name":"CONSULTANT PHARMACIST","volume":"33 7","pages":"382-385"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4140/TCP.n.2018.382","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36304770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}