Contemporary British History最新文献_第8页

The welfare state generation: women, agency and class in Britain since 1945 福利国家的一代:1945年以来英国的女性、机构和阶级

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-06-13 DOI: 10.1080/13619462.2022.2088517

L. Abrams

引用次数: 2

The Beatles and Sixties Britain 披头士乐队与六十年代的英国

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-06-13 DOI: 10.1080/13619462.2022.2088519

Gillian A. M. Mitchell

引用次数: 0

Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer. Th22 细胞/IL-22 通过 JAK-STAT3/MAPK/AKT 信号通路在非小细胞肺癌中充当原发肿瘤调控因子，导致预后不良。

IF 4.1 2区历史学

Contemporary British History Pub Date : 2022-05-28 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8071234

Yinan Yao, Guangdie Yang, Guohua Lu, Jiani Ye, Luyun Cui, Zhu Zeng, Junjun Chen, Jianying Zhou

{"title":"Th22 Cells/IL-22 Serves as a Protumor Regulator to Drive Poor Prognosis through the JAK-STAT3/MAPK/AKT Signaling Pathway in Non-Small-Cell Lung Cancer.","authors":"Yinan Yao, Guangdie Yang, Guohua Lu, Jiani Ye, Luyun Cui, Zhu Zeng, Junjun Chen, Jianying Zhou","doi":"10.1155/2022/8071234","DOIUrl":"10.1155/2022/8071234","url":null,"abstract":"The interaction of immune cells and cytokines in the tumor microenvironment affects the development and prognosis of tumors with an unclear potential regulatory mechanism. Recent studies have elucidated the protumor role of Th22 cells and its lineage-specific cytokine IL-22 in different human cancers. The present study is aimed at investigating the biological effect of Th22 cells/IL-22 and its molecular mechanism in the pathogenesis process of non-small-cell lung cancer (NSCLC). It was initially found that Th22 cells were enriched in the peripheral blood of NSCLC patients. The level of Th22 cells in peripheral blood mononuclear cells (PBMCs) was positively correlated with the TNM stage, lymph node metastasis, and clinical tumor biomarkers. Furthermore, IL-22 not only antagonized the apoptosis inducing and cell cycle arresting effect by chemotherapy and molecular targeted drugs on NSCLC cell lines but also promoted tumor cell proliferation and tumor tissue growth. Moreover, IL-22 activated the JAK-STAT3/MAPK/AKT signaling pathway, both in vitro and in vivo. Conclusively, the present results confirm that Th22 cells/IL-22 may serve as a negative immune regulator in lung cancer.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"26 1","pages":"8071234"},"PeriodicalIF":4.1,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9167127/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82434318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

The stress of work and work of stress in Britain in the late twentieth century 二十世纪末英国的工作压力和工作压力

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-05-28 DOI: 10.1080/13619462.2022.2081549

J. Kirby

引用次数: 1

Creating a ‘deplorable impression’: the Dryden Society’s 1969 tour of South Africa and the making of End of the Dialogue 制造“可悲的印象”：德莱顿学会1969年南非之行和《对话的终结》的制作

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-05-19 DOI: 10.1080/13619462.2022.2076078

D. Feather

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引用次数: 0

‘The moral rearmament of imperialism’: the Revolutionary Communist Party, the Northern Ireland conflict, and the new world order, 1981-1994 “帝国主义的道德重整”:革命共产党、北爱尔兰冲突和世界新秩序，1981-1994

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-04-28 DOI: 10.1080/13619462.2022.2070479

J. Hepworth

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引用次数: 0

Voice and choice: making a case for tailored smoking cessation programmes to support women experiencing homelessness. 声音与选择：为支持无家可归妇女而量身定制的戒烟计划提供依据。

2区历史学

Contemporary British History Pub Date : 2022-04-26 DOI: 10.1136/ebnurs-2022-103536

Maxine Radcliffe, Thilo Kroll, Kate Frazer

引用次数: 0

Productive European cooperation between Britain and Germany: the Swansea-Mannheim town twinning partnership and exchanges between Wales and Baden-Württemberg, 1950-2000 英国和德国之间富有成效的欧洲合作:斯旺西-曼海姆镇的结对伙伴关系和威尔士和巴登-符腾堡州之间的交流，1950-2000

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-04-26 DOI: 10.1080/13619462.2022.2064282

Simon John

{"title":"Productive European cooperation between Britain and Germany: the Swansea-Mannheim town twinning partnership and exchanges between Wales and Baden-Württemberg, 1950-2000","authors":"Simon John","doi":"10.1080/13619462.2022.2064282","DOIUrl":"https://doi.org/10.1080/13619462.2022.2064282","url":null,"abstract":"ABSTRACT This article investigates the town twinning partnership between Swansea (South Wales) and Mannheim (Baden-Württemberg, Germany) from its inception in the 1950s to the end of the twentieth century. Its findings contribute to scholarship on post-1945 European town twinning, a subject that has not received the attention it deserves, especially from academics working in Britain. The article’s arguments also complicate wider debates surrounding post-war popular relations between Britain and Germany, which have often been cast in existing work as ambivalent or outright hostile. The article adopts a regional approach—emphasising interactions between Wales and Baden-Württemberg rather than at the national level—to offer a new perspective on international relations between Britain and Germany, showing that inhabitants of Swansea and Mannheim forged warm friendships and made efforts to understand each other. The article also highlights the limitations of purely Anglocentric approaches to modern British history, drawing from interactions carried out under the aegis of the Swansea-Mannheim partnership to trace ways in which Welsh identity and the Welsh language shaped external perceptions of the British.","PeriodicalId":45519,"journal":{"name":"Contemporary British History","volume":"36 1","pages":"552 - 590"},"PeriodicalIF":0.7,"publicationDate":"2022-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41376157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Whip in my valise: British punk and the Marquis de Sade, c. 1975–85 旅行箱里的鞭子:英国朋克与萨德侯爵，约1975-85年

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-04-03 DOI: 10.1080/13619462.2022.2051487

M. Worley

引用次数: 0

Spartacus magazine and the commercial-political nexus of Gay Liberation 斯巴达克斯杂志和同性恋解放的商业政治关系

IF 0.7 2区历史学

Contemporary British History Pub Date : 2022-04-03 DOI: 10.1080/13619462.2022.2053845

Gil Engelstein

引用次数: 2