Diabetic Foot & Ankle最新文献

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Current challenges in imaging of the diabetic foot. 当前糖尿病足影像学的挑战。
Diabetic Foot & Ankle Pub Date : 2012-01-01 Epub Date: 2012-10-01 DOI: 10.3402/dfa.v3i0.18754
S Eser Sanverdi, Bilge F Ergen, Ali Oznur
{"title":"Current challenges in imaging of the diabetic foot.","authors":"S Eser Sanverdi,&nbsp;Bilge F Ergen,&nbsp;Ali Oznur","doi":"10.3402/dfa.v3i0.18754","DOIUrl":"https://doi.org/10.3402/dfa.v3i0.18754","url":null,"abstract":"<p><p>Although a variety of diagnostic imaging modalities are available for the evaluation of diabetes-related foot complications, the distinction between neuroarthropathy and osteomyelitis is still challenging. The early and accurate diagnosis of diabetic foot complications can help reduce the incidence of infection-related morbidities, the need for and duration of hospitalization, and the incidence of major limb amputation. Conventional radiography, computed tomography, nuclear medicine scintigraphy, magnetic resonance imaging, ultrasonography, and positron emission tomography are the main procedures currently in use for the evaluation of diabetes-related foot complications. However, each of these modalities does not provide enough information alone and a multimodal approach should be used for an accurate diagnosis. The present study is a review of the current concepts in imaging of diabetes-related foot complications and an analysis of the advantages and disadvantages of each method.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"3 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v3i0.18754","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30964091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 57
Incidence of re-amputation following partial first ray amputation associated with diabetes mellitus and peripheral sensory neuropathy: a systematic review. 与糖尿病和周围感觉神经病变相关的部分一线截肢后再截肢的发生率:一项系统综述。
Diabetic Foot & Ankle Pub Date : 2012-01-01 Epub Date: 2012-01-20 DOI: 10.3402/dfa.v3i0.12169
Sara L Borkosky, Thomas S Roukis
{"title":"Incidence of re-amputation following partial first ray amputation associated with diabetes mellitus and peripheral sensory neuropathy: a systematic review.","authors":"Sara L Borkosky,&nbsp;Thomas S Roukis","doi":"10.3402/dfa.v3i0.12169","DOIUrl":"https://doi.org/10.3402/dfa.v3i0.12169","url":null,"abstract":"<p><p>Diabetes mellitus with peripheral sensory neuropathy frequently results in forefoot ulceration. Ulceration at the first ray level tends to be recalcitrant to local wound care modalities and off-loading techniques. If healing does occur, ulcer recurrence is common. When infection develops, partial first ray amputation in an effort to preserve maximum foot length is often performed. However, the survivorship of partial first ray amputations in this patient population and associated re-amputation rate remain unknown. Therefore, in an effort to determine the actual re-amputation rate following any form of partial first ray amputation in patients with diabetes mellitus and peripheral neuropathy, the authors conducted a systematic review. Only studies involving any form of partial first ray amputation associated with diabetes mellitus and peripheral sensory neuropathy but without critical limb ischemia were included. Our search yielded a total of 24 references with 5 (20.8%) meeting our inclusion criteria involving 435 partial first ray amputations. The weighted mean age of patients was 59 years and the weighted mean follow-up was 26 months. The initial amputation level included the proximal phalanx base 167 (38.4%) times; first metatarsal head resection 96 (22.1%) times; first metatarsal-phalangeal joint disarticulation 53 (12.2%) times; first metatarsal mid-shaft 39 (9%) times; hallux fillet flap 32 (7.4%) times; first metatarsal base 29 (6.7%) times; and partial hallux 19 (4.4%) times. The incidence of re-amputation was 19.8% (86/435). The end stage, most proximal level, following re-amputation was an additional digit 32 (37.2%) times; transmetatarsal 28 (32.6%) times; below-knee 25 (29.1%) times; and LisFranc 1 (1.2%) time. The results of our systematic review reveal that one out of every five patients undergoing any version of a partial first ray amputation will eventually require more proximal re-amputation. These results reveal that partial first ray amputation for patients with diabetes and peripheral sensory neuropathy may not represent a durable, functional, or predictable foot-sparing amputation and that a more proximal amputation, such as a balanced transmetatarsal amputation, as the index amputation may be more beneficial to the patient. However, this remains a matter for conjecture due to the limited data available and, therefore, additional prospective investigations are warranted.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2012-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v3i0.12169","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40146155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 68
The use of a combined bipedicled axial perforator based fasciocutaneous flap for the treatment of a traumatic diabetic foot wound: a case report. 应用联合双蒂轴向穿支筋膜皮瓣治疗糖尿病足创伤1例。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-02-07 DOI: 10.3402/dfa.v2i0.5749
Ioannis A Ignatiadis, Georgios D Georgakopoulos, Vassiliki A Tsiampa, Ileana R Matei, Alexandru V Georgescu, Vasilios D Polyzois
{"title":"The use of a combined bipedicled axial perforator based fasciocutaneous flap for the treatment of a traumatic diabetic foot wound: a case report.","authors":"Ioannis A Ignatiadis,&nbsp;Georgios D Georgakopoulos,&nbsp;Vassiliki A Tsiampa,&nbsp;Ileana R Matei,&nbsp;Alexandru V Georgescu,&nbsp;Vasilios D Polyzois","doi":"10.3402/dfa.v2i0.5749","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.5749","url":null,"abstract":"<p><p>The axial and perforator vascularised fasciocutaneous flaps are reliable and effective treatment methods for covering lower limb post-traumatic, septic, Charcot, and diabetic foot wounds. The authors describe the unique utilisation of a hybrid flap as an axial-perforator flap combination for the treatment of a traumatic diabetic foot wound.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.5749","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40144064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The reverse sural fasciocutaneous flap for the treatment of traumatic, infectious or diabetic foot and ankle wounds: A retrospective review of 16 patients. 腓肠逆筋膜皮瓣治疗外伤性、感染性或糖尿病性足部及踝部伤口16例回顾性分析。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-01-12 DOI: 10.3402/dfa.v2i0.5653
Ioannis A Ignatiadis, Vassiliki A Tsiampa, Spyridon P Galanakos, Georgios D Georgakopoulos, Nicolaos E Gerostathopoulos, Mihai Ionac, Lucian P Jiga, Vasilios D Polyzois
{"title":"The reverse sural fasciocutaneous flap for the treatment of traumatic, infectious or diabetic foot and ankle wounds: A retrospective review of 16 patients.","authors":"Ioannis A Ignatiadis,&nbsp;Vassiliki A Tsiampa,&nbsp;Spyridon P Galanakos,&nbsp;Georgios D Georgakopoulos,&nbsp;Nicolaos E Gerostathopoulos,&nbsp;Mihai Ionac,&nbsp;Lucian P Jiga,&nbsp;Vasilios D Polyzois","doi":"10.3402/dfa.v2i0.5653","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.5653","url":null,"abstract":"<p><p>The authors present their experience with the use of sural fasciocutaneous flaps for the treatment of various soft tissue defects in the lower limb. This paper is a review of these flaps carried out between 2003 and 2008. The series consists of 16 patients, 11 men and 5 women with an average age of 41 years (17-81) and with a follow-up period between 2 and 7 years. The etiology was major velocity accident in six cases, diabetes mellitus with osteomyelitis after ORIF for fractures (2), work accident in five, and another two cases with complications of lower limb injuries. The defect areas were located on calcaneus, malleolar area, tarsal area and lower tibia. Associated risk factors in the patients for the flap performance were diabetes (five patients) and cigarette smoking (ten patients).The technique is based on the use of a reverse-flow island sural flap combined with other flaps in three cases (cross-leg, peroneal, gastrocnemius). The anatomical structures which constituted the pedicle were the superficial and deep fascia, the sural nerve, the lesser saphenous vein and skin.The flap was viable in all 15 patients. On 8 cases was achieved direct closure, on three cases occurred a superficial necrosis and was skin grafted, on one case was observed partial necrosis which was treated with a second flap (posterior tibial perforator flap) and another one occurred delayed skin healing.The sural fasciocutaneous flap is useful for the treatment of severe and complex injuries and their complications in diabetic and non diabetic lower limbs. Its technical advantages are easy dissection, preservation of more important vascular structures in the limb and complete coverage of the soft tissue defects in just one operation without the need of microsurgical anastomosis. Thus this flap offers excellent donor sites for repairing soft tissue defects in foot and ankle.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.5653","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40145656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 33
A systematic approach to the failed plastic surgical reconstruction of the diabetic foot. 糖尿病足整形手术重建失败的系统方法。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-05-11 DOI: 10.3402/dfa.v2i0.6435
Ioannis I Ignatiadis, Vassiliki A Tsiampa, Apostolos E Papalois
{"title":"A systematic approach to the failed plastic surgical reconstruction of the diabetic foot.","authors":"Ioannis I Ignatiadis,&nbsp;Vassiliki A Tsiampa,&nbsp;Apostolos E Papalois","doi":"10.3402/dfa.v2i0.6435","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.6435","url":null,"abstract":"<p><p>Plastic reconstruction for diabetic foot wounds must be approached carefully and follow sound micro-surgical principles as it relates to the anatomy of the designated flap chosen for coverage. First, the surgeon always needs to evaluate the local and general conditions of the presenting pathology and patient, respectively when considering a flap for reconstruction. The flap that is chosen is based on the vascularity, location, and size of the defect. Salvage of the failed flap and revisional reconstructive procedures are very challenging. Often, adjunctive therapies such as hyperbaric oxygen, negative pressure wound therapy, vasodilators, and/or vascular surgery is required. In certain case scenarios, such as patients with poor general health and compromised local vascularity in which revisional flap coverage cannot be performed, the above mentioned adjunctive therapies could be used as a primary treatment to potentially salvage a failing flap.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.6435","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40146150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Minimally invasive surgery for diabetic plantar foot ulcerations. 微创手术治疗糖尿病足底溃疡。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-11-25 DOI: 10.3402/dfa.v2i0.10358
Fábio Batista, Antonio Augusto Magalhães, Caio Nery, Daniel Baumfeld, Augusto César Monteiro, Fabíola Batista
{"title":"Minimally invasive surgery for diabetic plantar foot ulcerations.","authors":"Fábio Batista,&nbsp;Antonio Augusto Magalhães,&nbsp;Caio Nery,&nbsp;Daniel Baumfeld,&nbsp;Augusto César Monteiro,&nbsp;Fabíola Batista","doi":"10.3402/dfa.v2i0.10358","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.10358","url":null,"abstract":"<p><p>Complications of diabetes mellitus constitute the most common indications for hospitalization and non-traumatic amputations in the USA. The most important risk factors for the development of diabetic foot ulcerations include the presence of peripheral neuropathy, vasculopathy, limited joint mobility, and pre-existing foot deformities. In our study, 500 diabetic patients treated for plantar forefoot ulcerations were enrolled in a prospective study from 2000 to 2008 at the Federal University of São Paulo, Brazil. Fifty-two patients in the study met the criteria and underwent surgical treatment consisting of percutaneous Achilles tendon lengthening to treat plantar forefoot ulcerations. The postoperative follow-up demonstrated prevention of recurrent foot ulcerations in 92% of these diabetic patients that maintained an improved foot function. In conclusion, our study supports that identification and treatment of ankle equinus in the diabetic population may potentially lead to decreased patient morbidity, including reduced risk for both reulceration, and potential lower extremity amputation.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.10358","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40146153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
An overview of conservative treatment options for diabetic Charcot foot neuroarthropathy. 糖尿病Charcot足神经关节病的保守治疗方案综述。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-05-11 DOI: 10.3402/dfa.v2i0.6418
Crystal L Ramanujam, Zacharia Facaros
{"title":"An overview of conservative treatment options for diabetic Charcot foot neuroarthropathy.","authors":"Crystal L Ramanujam,&nbsp;Zacharia Facaros","doi":"10.3402/dfa.v2i0.6418","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.6418","url":null,"abstract":"<p><p>Conservative management of Charcot foot neuroarthropathy remains efficacious for certain clinical scenarios. Treatment of the patient should take into account the stage of the Charcot neuroarthopathy, site(s) of involvement, presence or absence of ulceration, presence or absence of infection, overall medical status, and level of compliance. The authors present an overview of evidence-based non-operative treatment for diabetic Charcot neuroarthropathy with an emphasis on the most recent developments in therapy.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.6418","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40146154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
Management of diabetic neuropathic foot and ankle malunions and nonunions. 糖尿病神经性足、踝畸形连和不连的处理。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-05-11 DOI: 10.3402/dfa.v2i0.6287
John J Stapleton
{"title":"Management of diabetic neuropathic foot and ankle malunions and nonunions.","authors":"John J Stapleton","doi":"10.3402/dfa.v2i0.6287","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.6287","url":null,"abstract":"<p><p>The management of diabetic neuropathic foot and ankle malunions and/or nonunions is often complicated by the presence of broken or loosened hardware, Charcot joints, infection, osteomyelitis, avascular bone necrosis, unstable deformities, bone loss, disuse and pathologic osteopenia, and ulcerations. The author discusses a rational approach to functional limb salvage with various surgical techniques that are aimed at achieving anatomic alignment, long-term osseous stability, and adequate soft tissue coverage. Emphasis is placed on techniques to overcome the inherent challenges that are encountered when surgically managing a diabetic nonunion and/or malunion. Particular attention is directed to the management of deep infection and Charcot neuroarthropathy in the majority of the cases presented.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.6287","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40144063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
German-Austrian consensus on operative treatment of Charcot neuroarthropathy: a Perspective by the Charcot task force of the German Association for Foot Surgery. 德国和奥地利对Charcot神经关节病手术治疗的共识:德国足外科协会Charcot工作组的观点。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-11-09 DOI: 10.3402/dfa.v2i0.10207
Armin Koller, Ralph Springfeld, Gerald Engels, Raimund Fiedler, Ernst Orthner, Stefan Schrinner, Alexander Sikorski
{"title":"German-Austrian consensus on operative treatment of Charcot neuroarthropathy: a Perspective by the Charcot task force of the German Association for Foot Surgery.","authors":"Armin Koller,&nbsp;Ralph Springfeld,&nbsp;Gerald Engels,&nbsp;Raimund Fiedler,&nbsp;Ernst Orthner,&nbsp;Stefan Schrinner,&nbsp;Alexander Sikorski","doi":"10.3402/dfa.v2i0.10207","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.10207","url":null,"abstract":"A number of published guidelines exist on the diabetic foot, yet the sections on Charcot neuroarthropathy (CN) focus mainly on diagnosis and conservative therapy. Surgical aspects, if ever present, are addressed very briefly and are very limited on surgical information and guidelines (1). For this reason, a group of German and Austrian foot surgeons who are well acquainted with the operative treatment of CN established a consensus statement despite a plethora of existing diverging opinions. The following proposal is far from scientific evidence, but may be the basis for an ongoing discussion and further research opportunity. (Published: 9 November 2011) Citation: Diabetic Foot & Ankle 2011, 2 : 10207 - DOI: 10.3402/dfa.v2i0.10207 Due to two errors in this article, an Erratum has been published: Citation: Diabetic Foot & Ankle 2011, 2 : 14920 - DOI: 10.3402/dfa.v2i0.14920","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.10207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40146152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Predictive factors for lower extremity amputations in diabetic foot infections. 糖尿病足感染下肢截肢的预测因素。
Diabetic Foot & Ankle Pub Date : 2011-01-01 Epub Date: 2011-09-20 DOI: 10.3402/dfa.v2i0.7463
Zameer Aziz, Wong Keng Lin, Aziz Nather, Chan Yiong Huak
{"title":"Predictive factors for lower extremity amputations in diabetic foot infections.","authors":"Zameer Aziz,&nbsp;Wong Keng Lin,&nbsp;Aziz Nather,&nbsp;Chan Yiong Huak","doi":"10.3402/dfa.v2i0.7463","DOIUrl":"https://doi.org/10.3402/dfa.v2i0.7463","url":null,"abstract":"<p><p>The objective of this study was to evaluate the epidemiology of diabetic foot infections (DFIs) and its predictive factors for lower extremity amputations. A prospective study of 100 patients with DFIs treated at the National University Hospital of Singapore were recruited in the study during the period of January 2005-June 2005. A protocol was designed to document patient's demographics, type of DFI, presence of neuropathy and/or vasculopathy and its final outcome. Predictive factors for limb loss were determined using univariate and stepwise logistic regression analysis. The mean age of the study population was 59.8 years with a male to female ratio of about 1:1 and with a mean follow-up duration of about 24 months. All patients had type 2 diabetes mellitus. Common DFIs included abscess (32%), wet gangrene (29%), infected ulcers (19%), osteomyelitis (13%), necrotizing fasciitis (4%) and cellulitis (3%). Thirteen patients were treated conservatively, while surgical debridement or distal amputation was performed in 59 patients. Twenty-eight patients had major amputations (below or above knee) performed. Forty-eight percent had monomicrobial infections compared with 52% with polymicrobial infections. The most common pathogens found in all infections (both monomicrobial and polymicrobial) were Staphylococcus aureus (39.7%), Bacteroides fragilis (30.3%), Pseudomonas aeruginosa (26.0%) and Streptococcus agalactiae (21.0%). Significant univariate predictive factors for limb loss included age above 60 years, gangrene, ankle-brachial index (ABI) <0.8, monomicrobial infections, white blood cell (WBC) count ≥ 15.0×10(9)/L, erythrocyte sedimentation rate ≥100 mm/hr, C-reactive protein ≥15.0 mg/dL, hemoglobin (Hb) ≤10.0g/dL and creatinine ≥150 µmol/L. Upon stepwise logistic regression, only gangrene, ABI <0.8, WBC ≥ 15.0×10(9)/L and Hb ≤10.0g/dL were significant.</p>","PeriodicalId":45385,"journal":{"name":"Diabetic Foot & Ankle","volume":"2 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3402/dfa.v2i0.7463","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40145654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 72
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