{"title":"Agency, writing, and the exercise of power. Secretaries in Ancien Régime France","authors":"Nicolas Schapira","doi":"10.1408/100612","DOIUrl":"https://doi.org/10.1408/100612","url":null,"abstract":"","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"1 1","pages":"829-853"},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66643080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"«Contracts damned by God and by the World». Litigating the just price in seventeenth century Venice","authors":"James E. Shaw","doi":"10.1408/98278","DOIUrl":"https://doi.org/10.1408/98278","url":null,"abstract":"","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"1 1","pages":"185-210"},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66651234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Defending the commons. Scientific and human issues of a direct-hand experience","authors":"Stefano Barbacetto","doi":"10.1408/99419","DOIUrl":"https://doi.org/10.1408/99419","url":null,"abstract":"","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"1 1","pages":"591-624"},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66651327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fathers and married daughters in nineteenth-century Greece","authors":"Evdoxios Doxiadis","doi":"10.1408/100610","DOIUrl":"https://doi.org/10.1408/100610","url":null,"abstract":"","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"1 1","pages":"791-808"},"PeriodicalIF":0.2,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66643027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Carità, salvezza e profitto terreno. Alcune riflessioni sull’economia della povertà tratte dall’esempio dei Pazzi di Avignone (XIV-XV secolo","authors":"Clément Lenoble","doi":"10.1408/97818","DOIUrl":"https://doi.org/10.1408/97818","url":null,"abstract":"Charity, salvation and profit are related during the last centuries of the Middle Ages in the texts of the scholastics and in the current practices of merchants and public institutions, as is often attested by the archives of hospitals and Mounts of Piety. Exchanges between the Pazzi family and the convent of the Friars Minor in Avignon in the 15th century suggest that the relationships between merchants and convents may have followed the same logic by relying on legal categories which associate natural obligations and ius commune.","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"162 1","pages":"619-637"},"PeriodicalIF":0.2,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44186129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
QUADERNI STORICIPub Date : 2019-10-01Epub Date: 2019-09-26DOI: 10.1111/head.13661
Claire E J Ceriani, Danielle A Wilhour, Stephen D Silberstein
{"title":"Novel Medications for the Treatment of Migraine.","authors":"Claire E J Ceriani, Danielle A Wilhour, Stephen D Silberstein","doi":"10.1111/head.13661","DOIUrl":"10.1111/head.13661","url":null,"abstract":"<p><strong>Objective: </strong>To describe the new classes of medication for headache management and their roles in clinical practice.</p><p><strong>Background: </strong>Calcitonin gene-related peptide (CGRP) is a key component in the underlying pathophysiology of migraine. Research focused on targeting CGRP for headache treatment has led to the development of entirely new classes of medications - the gepants and the CGRP monoclonal antibodies (mAbs) - for both acute and preventive treatment. A third class, the ditans, is being developed to target the 5-HT<sub>1F</sub> receptor to provide acute treatment without vasoconstrictive effects.</p><p><strong>Methods: </strong>This article reviews the pathophysiology of migraine that has led to these new pharmacologic developments. Available information from randomized controlled trials, abstracts, press releases, and relevant preclinical studies is summarized for each class of medications.</p><p><strong>Results: </strong>At the time of this writing, one ditan has been submitted to the U.S. Food and Drug Administration (FDA) for approval. One gepant is anticipated to be submitted within the first quarter of 2019, and others are in clinical trials. Three CGRP mAbs have been FDA approved and are now available in clinical practice, and a fourth was submitted in the first quarter of 2019.</p><p><strong>Conclusions: </strong>The development of new migraine-specific classes of medications provides more treatment options for both acute and preventive treatment of migraine.</p>","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"1 1","pages":"1597-1608"},"PeriodicalIF":0.0,"publicationDate":"2019-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/head.13661","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88740902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contentious memories. Territorial control and the creation of heritage in Indian-occupied Kashmir","authors":"F. Recchia","doi":"10.1408/96903","DOIUrl":"https://doi.org/10.1408/96903","url":null,"abstract":"","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"1 1","pages":"353-370"},"PeriodicalIF":0.2,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66650921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A proposito di «Lier et délier la proprieté» di Jean-François Chauvard","authors":"Paola Lanaro, M. Aymard, A. Bellavitis","doi":"10.1408/95922","DOIUrl":"https://doi.org/10.1408/95922","url":null,"abstract":"","PeriodicalId":45303,"journal":{"name":"QUADERNI STORICI","volume":"55 27 1","pages":"259-271"},"PeriodicalIF":0.2,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66650877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}