JOURNAL OF RELIGION最新文献

ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection. ADBP-1 调节 ADR-2 的核定位，以控制编辑底物的选择。

3区哲学

JOURNAL OF RELIGION Pub Date : 2024-06-09 DOI: 10.1101/2023.05.14.540679

Berta Eliad, Noa Schneider, Orna Ben-Naim Zgayer, Yarden Amichan, Fabian Glaser, Emily A Erdmann, Suba Rajendren, Heather A Hundley, Ayelet T Lamm

{"title":"ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection.","authors":"Berta Eliad, Noa Schneider, Orna Ben-Naim Zgayer, Yarden Amichan, Fabian Glaser, Emily A Erdmann, Suba Rajendren, Heather A Hundley, Ayelet T Lamm","doi":"10.1101/2023.05.14.540679","DOIUrl":"10.1101/2023.05.14.540679","url":null,"abstract":"Adenosine-to-inosine (A-to-I) RNA editing, catalyzed by ADAR enzymes, is a prevalent and conserved RNA modification. While A-to-I RNA editing is essential in mammals, in Caenorhabditis elegans , it is not, making them invaluable for RNA editing research. In C. elegans , ADR-2 is the sole catalytic A-to-I editing enzyme, and ADR-1 is an RNA editing regulator. ADAR localization is well-studied in humans but not well-established in C. elegans . In this study, we examine the cellular and tissue-specific localization of ADR-2. We show that while ADR-2 is present in most cells in the embryo, at later developmental stages, its expression is both tissue- and cell-type-specific. Additionally, both ADARs are mainly in the nucleus. ADR-2 is adjacent to the chromosomes during the cell cycle. We show that the nuclear localization of endogenous ADR-2 depends on ADBP-1, not ADR-1. In adbp-1 mutant worms, ADR-2 is mislocalized, while ADR-1 is not, leading to decreased editing levels and de-novo editing, mostly in exons, suggesting that ADR-2 is also functional in the cytoplasm. Besides, mutated ADBP-1 affects gene expression. Furthermore, we show that ADR-2 targets adenosines with different surrounding nucleotides in exons and introns. Our findings indicate that ADR-2 cellular localization is highly regulated and affects its function.","PeriodicalId":45199,"journal":{"name":"JOURNAL OF RELIGION","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82361492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Updating the sulcal landscape of the human lateral parieto-occipital junction provides anatomical, functional, and cognitive insights. 更新人类外侧顶枕交界处的沟状景观，提供解剖、功能和认知方面的见解。

3区哲学

JOURNAL OF RELIGION Pub Date : 2024-05-14 DOI: 10.1101/2023.06.08.544284

Ethan H Willbrand, Yi-Heng Tsai, Thomas Gagnant, Kevin S Weiner

{"title":"Updating the sulcal landscape of the human lateral parieto-occipital junction provides anatomical, functional, and cognitive insights.","authors":"Ethan H Willbrand, Yi-Heng Tsai, Thomas Gagnant, Kevin S Weiner","doi":"10.1101/2023.06.08.544284","DOIUrl":"10.1101/2023.06.08.544284","url":null,"abstract":"Recent work has uncovered relationships between evolutionarily new small and shallow cerebral indentations, or sulci, and human behavior. Yet, this relationship remains unexplored in the lateral parietal cortex (LPC) and the lateral parieto-occipital junction (LPOJ). After defining thousands of sulci in a young adult cohort, we revised the previous LPC/LPOJ sulcal landscape to include four previously overlooked, small, shallow, and variable sulci. One of these sulci (ventral supralateral occipital sulcus, slocs-v) is present in nearly every hemisphere and is morphologically, architecturally, and functionally dissociable from neighboring sulci. A data-driven, model-based approach, relating sulcal depth to behavior further revealed that the morphology of only a subset of LPC/LPOJ sulci, including the slocs-v, is related to performance on a spatial orientation task. Our findings build on classic neuroanatomical theories and identify new neuroanatomical targets for future \"precision imaging\" studies exploring the relationship among brain structure, brain function, and cognitive abilities in individual participants.","PeriodicalId":45199,"journal":{"name":"JOURNAL OF RELIGION","volume":"86 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11118496/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82430762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

:Practicing Atheism: Culture, Media, and Ritual in the Contemporary Atheist Network ：实践无神论：当代无神论网络中的文化、媒体和仪式

IF 0.3 3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/724851

M. Ruse

引用次数: 0

:The Formation of Post-Classical Philosophy in Islam 伊斯兰教后古典哲学的形成

IF 0.3 3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/724842

Mehmet Emin Gulecyuz

引用次数: 0

:Monotheism, Intolerance, and the Path to Pluralistic Politics ：一神论、不容忍与多元政治之路

IF 0.3 3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/724857

P. Powers

引用次数: 0

Review of Jeremy David Engels’s The Ethics of Oneness: Emerson, Whitman, and the Bhagavad Gita 恩格斯《合一伦理学》述评：爱默生、惠特曼与薄伽梵歌

IF 0.3 3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/724970

D. Dilworth

引用次数: 0

A Calvinist Confession? Interpreting the Thirty-Nine Articles and Writing the History of the Reformation in Eighteenth-Century Ireland 加尔文主义的忏悔？解读三十九篇文章，书写十八世纪爱尔兰宗教改革史

IF 0.3 3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/725062

Simon Lewis

{"title":"A Calvinist Confession? Interpreting the Thirty-Nine Articles and Writing the History of the Reformation in Eighteenth-Century Ireland","authors":"Simon Lewis","doi":"10.1086/725062","DOIUrl":"https://doi.org/10.1086/725062","url":null,"abstract":"In eighteenth-century Ireland, there were two competing historiographical traditions, fighting to tell their story of the Church of Ireland’s doctrinal heritage, as outlined in its confession, the Thirty-Nine Articles, which were formulated in the sixteenth-century Church of England. Article XVII: Of Predestination and Election—the most controversial article—contained no reference to the “reprobate.” Mainstream Anglican clergymen, who taught an Arminian soteriology, cited this omission as proof that the sixteenth-century framers had not intended Article XVII to be read in a Calvinist light. These “Caroline” historians also stressed the importance of the Laudian reforms of the 1630s, when the Irish Church’s original, ultra-Calvinist confession, the 1615 Articles, were virtually (but not officially) rescinded in favor of the English Church’s allegedly un-Calvinist confession, the Thirty-Nine Articles. There was, however, another, resolutely Protestant historiographical tradition, stressing the Irish Church’s doctrinal links with the continental Reformation. Proponents of this tradition argued that the Thirty-Nine Articles needed to be read in the light of the 1615 Articles, which, they claimed, remained an authoritative confession in the Irish Church. This essay explores how contemporaries interpreted and reinterpreted the Thirty-Nine Articles, thereby illuminating the ways in which the historiography of the Reformation was shaped by politico-theological concerns in eighteenth-century Ireland. It displays the eighteenth century as a fundamental period of transition, in which a largely dormant historiographical tradition was revived in the Irish Church by a small but growing faction of evangelicals, who sought to write Calvinism back into the history of their denomination.","PeriodicalId":45199,"journal":{"name":"JOURNAL OF RELIGION","volume":"103 1","pages":"338 - 364"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47179219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"哲学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

:Image: Three Inquiries in Technology and Imagination 图片:《技术与想象的三个调查》

IF 0.3 3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/724846

W. Robert

引用次数: 0

Front Matter 前页

3区哲学

JOURNAL OF RELIGION Pub Date : 2023-07-01 DOI: 10.1086/726771

引用次数: 0

:Anarchy and the Kingdom of God: From Eschatology to Orthodox Political Theology and Back ：无政府状态与上帝的王国：从末世论到正统政治神学及其回归

IF 0.3 3区哲学