Electronic Journal of General Medicine最新文献_第5页

A rare case of autoimmune dysglycemia syndrome associated with systemic lupus erythematosus and dermatomyositis 一例罕见的自身免疫性血糖异常综合征合并系统性红斑狼疮和皮肌炎

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13294

J. Paz-Ibarra, Marcio Concepción-Zavaleta, J. Quiroz-Aldave, Mikaela Kcomt Lam, Edwars Gilvonio Huauya, Diego Sueldo Espinoza, George Gago Cajacuri

{"title":"A rare case of autoimmune dysglycemia syndrome associated with systemic lupus erythematosus and dermatomyositis","authors":"J. Paz-Ibarra, Marcio Concepción-Zavaleta, J. Quiroz-Aldave, Mikaela Kcomt Lam, Edwars Gilvonio Huauya, Diego Sueldo Espinoza, George Gago Cajacuri","doi":"10.29333/ejgm/13294","DOIUrl":"https://doi.org/10.29333/ejgm/13294","url":null,"abstract":"Autoimmune dysglycemia syndrome (ADS) is a rare condition that presents as episodes of hypoglycemia as well as hyperglycemia and is classified as insulin autoimmune syndrome (IAS) and type B insulin resistance (TBIR). Autoimmunity plays a key role in the pathogenesis of this disorder, as evidenced by the presence of autoantibodies against endogenous insulin or the insulin receptor, and by its association with rheumatologic disorders. Treatment usually includes glycemic control and immunomodulatory agents. We report a case of a 31-year-old woman who was admitted for severe hypoglycemia. Further workup revealed underlying systemic lupus erythematosus (SLE) with renal involvement. During hospitalization, she continued to experience episodes of fasting hypoglycemia, as well as episodes of postprandial hyperglycemia. Hypoglycemia associated with a high serum insulin concentration and positive anti-insulin antibodies were consistent with IAS. Likewise, hyperglycemia and hypoglycemia in association with weight loss, acanthosis nigricans, polycystic ovarian syndrome, and normotriglyceridemia strongly suggested TBIR, although testing for antibodies against the insulin receptor was not available in Peru. Immunosuppressive therapy and metformin were indicated, resulting in remission of SLE and ADS. Years later, the patient exhibited features of dermatomyositis, such as Raynaud’s phenomenon, muscular weakness, heliotrope exanthema, and elevated muscle enzymes. Once again, the patient received immunosuppressive therapy. ADS is an infrequent cause of hypoglycemia, and the coexistence of its two pathophysiological mechanisms in a patient with SLE and subsequent development of dermatomyositis is even more rare. Our case is the first one reported describing this association.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43016585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of the early stages of the COVID-19 pandemic on academic studies, clinical training, and their opinion on vaccination among radiography students 新冠肺炎大流行早期阶段对放射科学生学术研究、临床培训的影响及其对疫苗接种的看法

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13413

K. Alzyoud, S. Al-Murshedi, A. England

{"title":"The impact of the early stages of the COVID-19 pandemic on academic studies, clinical training, and their opinion on vaccination among radiography students","authors":"K. Alzyoud, S. Al-Murshedi, A. England","doi":"10.29333/ejgm/13413","DOIUrl":"https://doi.org/10.29333/ejgm/13413","url":null,"abstract":"Objectives: Since its inception, the COVID-19 pandemic has generated challenges for healthcare professions and educational institutions worldwide. This study aimed to investigate the effect of COVID-19 on radiography students’ education in Jordan.\u0000Method: A cross-sectional online survey was conducted during the initial COVID-19 lockdown period (31 March to 30 May 2020). All diagnostic radiography year groups at governmental universities (the Hashemite University, Al-Hussein Bin Talal University, and Jordan University of Science and Technology) were invited to complete the anonymous survey in Jordanian using Microsoft Forms.\u0000Results: There were 417 responses. Findings showed that Jordan’s radiography students’ education has been significantly impacted by the COVID-19 epidemic. The majority of survey participants were not convinced the online learning platforms were user-friendly. Comparing remote teaching versus face-to-face instruction, 51% of participants had difficulty concentrating. Access to clinical placements was the biggest issue raised; 86% of respondents stated that their clinical experience differed from what was outlined in the curriculum. 42% of the students were in favor of receiving the COVID-19 vaccines.\u0000Conclusions: Clinical radiography education in Jordan has been significantly impacted by the COVID-19 pandemic. The availability of necessary facilities for online training, the efficiency of the online platforms, and motivation to learn were the significant issues. The adoption of blended learning strategies and the use of simulation to enhance practical placement chances need to be taken into consideration when developing future training curricula and responses to pandemics.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47865009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Artificial intelligence and improvement of stem cell delivery in healthcare 人工智能与医疗保健中干细胞递送的改进

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13383

Tungki Pratama Umar

引用次数: 0

Hearing impairment in relation to vitamin D status in type 2 diabetic patients: A cross-sectional study 听力损害与2型糖尿病患者维生素D状况的关系:一项横断面研究

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13467

F. Elhussieny, I. Eladawy, I. Ahmad, E. Mahmoud, N. El-Khouly, Ghada F Elmohaseb, Asmaa F Elsyed, E. Youssef, Eman S M Bayoumy, S. A. Abd Elhamed

{"title":"Hearing impairment in relation to vitamin D status in type 2 diabetic patients: A cross-sectional study","authors":"F. Elhussieny, I. Eladawy, I. Ahmad, E. Mahmoud, N. El-Khouly, Ghada F Elmohaseb, Asmaa F Elsyed, E. Youssef, Eman S M Bayoumy, S. A. Abd Elhamed","doi":"10.29333/ejgm/13467","DOIUrl":"https://doi.org/10.29333/ejgm/13467","url":null,"abstract":"Objectives: To evaluate the association of serum 25 hydroxy vitamin D (25OHD) and hearing impairment type 2 diabetes mellitus (T2DM) patients. In addition, we aimed to examine whether T2DM-associated hearing impairment is correlated with the severity of diabetes.\u0000Methods: The present case-control study recruited adult patients with T2DM and healthy controls. Using pure-tone stimuli, we used an audiometer to assess the hearing thresholds of air conduction in each ear separately.\u0000Results: 84 patients and 32 volunteers were included. The serum 25OHD was lower in T2DM patients than in healthy control (12.24±1.3 versus 23.19±5.69, respectively; p<0.001). The prevalence of vitamin D deficiency was 100% in the T2DM group, compared to 25% in the control group (p=0.001). T2DM patients exhibited higher hearing thresholds at all tested frequencies compared to the control group (p<0.001). Diabetic patients with hearing impairment had a significantly lower serum 25OHD than the normal hearing group (11.7±1.2 versus 12.6±1.2 ng/d; p=0.02). The multivariate analysis demonstrated that serum 25OHD level was an independent predictor of hearing loss among diabetic patients (β=-0.605; p=0.041).\u0000Conclusions: the present study highlights the potential role of vitamin D deficiency in developing hearing impairment in the setting of T2DM. We found a negative correlation between serum 25OHD level and air conduction thresholds at low-mid and high frequencies amongst patients with T2DM.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45259877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuity of care in acromegaly: Detecting and managing recurrence after surgical intervention 肢端肥大症护理的连续性：手术干预后复发的检测和管理

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13293

Alia Fahizha Fahimi, Juliawati Muhammad, F. Mohd Zin, Nur Suhaila Idris

{"title":"Continuity of care in acromegaly: Detecting and managing recurrence after surgical intervention","authors":"Alia Fahizha Fahimi, Juliawati Muhammad, F. Mohd Zin, Nur Suhaila Idris","doi":"10.29333/ejgm/13293","DOIUrl":"https://doi.org/10.29333/ejgm/13293","url":null,"abstract":"Acromegaly is a rare disease being followed up by primary care team. It is usually caused by pituitary adenoma and the treatment would be resection of the tumour. But is surgical intervention the end of treatment for acromegalic patient? This case highlighted the continuity of care in a 65-year old gentleman who had been diagnosed acromegaly since the age of 31. He had undergone a transseptal transsphenoidal resection of his pituitary adenoma when he was 45-year-old. Postoperatively, there were still residual growth hormone (GH) and insulin like growth factor (IGF-1) secretions. However, during 20 years follow up after operation, despite the increasing level of GH and IGF-1, the management of acromegaly were neglected as the focus of treatment were shifted towards his other medical problem, which is diabetes and atrial fibrillation. During his latest follow up, his complaint of unspecified headache and expressed his worry regarding the recurrence of his condition. Repeated GH level showed an increase in its level and postulated the possibility of recurrent acromegaly. This case emphasizes the important of recognizing the level of GH and IGF-1 after surgical intervention in order to detect recurrence acromegaly by primary care and early referral to endocrine team.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43270838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exosomes in cancer therapy: Advances and current challenges 癌症治疗中的外泌体:进展和当前挑战

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13456

Rajib Dhar, A. Devi, S. Patil, M. Tovani-Palone

引用次数: 2

Pelvic floor muscle exercises plus biofeedback versus pelvic floor muscle exercises for patients with stress urinary incontinence: A systematic review and meta-analysis of randomized controlled trials 盆底肌锻炼加生物反馈与盆底肌训练治疗压力性尿失禁患者的比较：随机对照试验的系统综述和荟萃分析

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13411

Amina Pulatova, N. Mamedaliyeva, Gulzhakhan Omarova, Gulfairuz Urazbayeva, Ainura Veliyeva

{"title":"Pelvic floor muscle exercises plus biofeedback versus pelvic floor muscle exercises for patients with stress urinary incontinence: A systematic review and meta-analysis of randomized controlled trials","authors":"Amina Pulatova, N. Mamedaliyeva, Gulzhakhan Omarova, Gulfairuz Urazbayeva, Ainura Veliyeva","doi":"10.29333/ejgm/13411","DOIUrl":"https://doi.org/10.29333/ejgm/13411","url":null,"abstract":"Background: Stress urinary incontinence (SUI) is a widespread illness that mostly affects women, particularly those who have recently given birth or gone through menopause. The purpose of this meta-analysis is to compare the effectiveness of pelvic floor muscle exercises (PFME) plus biofeedback to PFME alone in treating SUI in female patients.\u0000Methods: We systemically searched six electronic databases (PubMed, Scopus, and Web of Science) from inception until February 7, 2022. We included randomized controlled trials (RTCs) comparing patients who had undergone PFME plus biofeedback to PFME alone. For risk of bias-2 (RoB2) assessment, we used cochrane risk of bias assessment tool. Continuous data were pooled as standardized mean difference (SMD), and dichotomous data were pooled as odds ratio with the corresponding 95% confidence intervals (CI).\u0000Results: 15 RCTs were included, with a total of 788 patients with SUI. The overall effect estimate between PFME+BF and PFME alone groups favored the PFME+BF group in improving PFME strength (SMD=0.33, 95% CI [0.14 to 0.52], p=.0009) and did not favor either of the two groups for quality of life (SMD=-0.22, 95% CI [-0.44 to 0.00], p=0.05), leakage (SMD=-0.10, 95% CI [-0.37 to 0.17], p=0.47), pad weight test (SMD=-0.22, 95% CI [-0.44 to 0.00], p=0.05), cure rate (odd ratio [OR]=2.44, 95% CI [0.52 to 11.42, p=0.26), and social activity (SMD=0.66, 95% CI [-0.04 to 1.36], p=0.07).\u0000Conclusion: BF addition to PRME improves cure rate and PFME strength without affecting leakage or quality of life. Healthcare providers must consider patient safety and comfort while choosing BF devices with PFME. SUI management strategies should include BF to improve results.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42704363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with poor health-related quality of life among patients with asthma: A hospital-based study from Jordan 哮喘患者健康相关生活质量差的相关因素：约旦一项基于医院的研究

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13384

A. Jarab, W. Al-Qerem, S. A. Abu Heshmeh, T. Mukattash, R. Beiram, S. Aburuz

{"title":"Factors associated with poor health-related quality of life among patients with asthma: A hospital-based study from Jordan","authors":"A. Jarab, W. Al-Qerem, S. A. Abu Heshmeh, T. Mukattash, R. Beiram, S. Aburuz","doi":"10.29333/ejgm/13384","DOIUrl":"https://doi.org/10.29333/ejgm/13384","url":null,"abstract":"Purpose: Exploring the factors that are associated with diminished health-related quality of life (HRQOL) in patients with asthma is essential to reach the optimal HRQOL. This study aim to assess HRQOL and its associated factors in patients with asthma in Jordan.\u0000Methods: This cross-sectional study was conducted on patients with asthma attending King Abdullah University Hospital and Jordan University Hospital in Jordan. In addition to socio-demographic variables, the study survey included mini asthma quality of life questionnaire (mini AQLQ) to measure HRQOL and asthma control test (ACT) to assess the degree of asthma control in asthmatic patients. Binary logistic regression was used to build a model of the independent predictors of poor HRQOL in the study participants.\u0000Results: Of the 314 participating patients, 70.1% were females, with a mean age of 51.47±16.37 years. 61.1% of the participants had low HRQOL, with a total mean mini AQLQ score of 4.30±1.30. Results revealed that advanced age (OR=0.961; 95% CI: 0.936-0.986; p<0.05) and lack of daily exercise (OR=0.233; 95% CI: 0.085-0.637; p<0.01) were significant predictors of poor HRQOL in patients with asthma, while better controlled disease, manifested by higher ACT score was associated with better HRQOL in these patients (OR=1.499; 95% CI: 1.344-1.672; p<0.01).\u0000Conclusions: HRQOL represents an area for improvement in patients with asthma. The current study provides insight on the factors associated with poor HRQOL. Future interventions and asthma management programs should focus on improving asthma control and encouraging physical activity, particularly for older patients, with the aim of improving HRQOL among patients with asthma.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46195974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of ankle dorsiflexion in sports performance and injury risk: A narrative review 踝关节背屈在运动表现和损伤风险中的作用:一个叙述性的回顾

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13412

Haifa Saleh Almansoof, S. Nuhmani, Q. Muaidi

引用次数: 1

Hematological and biochemical parameter changes among healthy individuals infected with COVID-19 according to sex and age: A hospital based study 新冠肺炎健康感染者根据性别和年龄的血液学和生化参数变化：一项基于医院的研究

IF 2.1

Electronic Journal of General Medicine Pub Date : 2023-09-01 DOI: 10.29333/ejgm/13468

Hamdi Adnan Haroon Hasanat, S. Saghir, Mahmoud Al-Areefi

{"title":"Hematological and biochemical parameter changes among healthy individuals infected with COVID-19 according to sex and age: A hospital based study","authors":"Hamdi Adnan Haroon Hasanat, S. Saghir, Mahmoud Al-Areefi","doi":"10.29333/ejgm/13468","DOIUrl":"https://doi.org/10.29333/ejgm/13468","url":null,"abstract":"Background: Numerous studies have linked COVID-19 to a range of human health problems, including high blood pressure, diabetes, and heart disease. Only a few research have focused on the specific effects of COVID-19 on healthy people. Consequently, this study was designed to investigate the effects of COVID-19 on hematological and biochemical markers among healthy people infected with COVID-19 patients according to sex, and age.\u0000Materials and methods: This study is a retrospective cross-sectional study conducted on 2,640 healthy people infected with COVID-19 in Jordan for the period from January 2021 to March 2022. Independent t-test and one-way ANOVA tests were used to compare the means of different groups.\u0000Results: In the present study, only 271 out of 2,640 COVID-19 cases met the criteria and were assessed according to sex and age. The average age of the study population was 57.90 years. The findings of this study revealed that statistically significant increases were noticed only in the levels of WBC, K, and ferritin of males compared with females. Similarly, statistically significant increases across various age groups were observed in WBC, MCV, MCH, PT, INR, and D-dimer levels. Moreover, statistically significant increases in FBS, creatinine, AST, CPK, CK-MB, ferritin, and LDH were seen when comparing the biochemical parameters across age groups.\u0000Conclusions: Patients infected with COVID-19 should be screened for all these studied hematological and biochemical parameters because the findings of the present study suggest that COVID-19 could lead to disturbances in, WBC, PT, APTT, d-dimer, INR, FBS, CR, urea, K, AST, ALT, ALP, LDH, CPK, CK-MB, and ferritin. We recommend clinical physicians to monitor patients’ conditions immediately by evaluating all of these parameters in order to prevent patients from deteriorating into life-threatening situations.","PeriodicalId":44930,"journal":{"name":"Electronic Journal of General Medicine","volume":" ","pages":""},"PeriodicalIF":2.1,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44014982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0