{"title":"Fundamentals of Reproductive Endocrinology","authors":"Derrick Ebot, H. Hilal, M. Carroll, J. Coey","doi":"10.1002/9781118977231.CH3","DOIUrl":"https://doi.org/10.1002/9781118977231.CH3","url":null,"abstract":"","PeriodicalId":448661,"journal":{"name":"Clinical Reproductive Science","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132891727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sexual Differentiation, Gonadal Development, and Development of the External Genitalia","authors":"R. M. Perrett","doi":"10.1002/9781118977231.CH1","DOIUrl":"https://doi.org/10.1002/9781118977231.CH1","url":null,"abstract":"The development of one’s sex comprises ‘sex determination’ – the development of the undifferentiated gonad into testis or ovaries during embryogenesis, followed by ‘sex differentiation’ – the determination of phenotypic sex induced by factors produced by the differentiated gonad. This chapter will highlight the molecular mechanisms underpinning these two processes. During the first 2 weeks of human embryonic development, the only difference between XX and XY embryos is their karyotype. At the two‐cell stage of the XX zygote, X chromosome inactivation occurs, enabling males and females to have equal transcript levels from the X chromosome (Huynh and Lee 2001). In developing germ cells, the X is reactivated in the female, so both X chromosomes contribute to oogenesis (Sugimoto and Abe 2007).","PeriodicalId":448661,"journal":{"name":"Clinical Reproductive Science","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128995325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Oocyte Aneuploidy and the Maternal Age Effect","authors":"M. Herbert","doi":"10.1002/9781118977231.CH11","DOIUrl":"https://doi.org/10.1002/9781118977231.CH11","url":null,"abstract":"","PeriodicalId":448661,"journal":{"name":"Clinical Reproductive Science","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116466430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Human Spermatozoa","authors":"A. Pacey, K. Williams","doi":"10.1002/9781118977231.CH5","DOIUrl":"https://doi.org/10.1002/9781118977231.CH5","url":null,"abstract":"","PeriodicalId":448661,"journal":{"name":"Clinical Reproductive Science","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121258013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Female Reproductive Tract and Early Embryo Development","authors":"H. Leese, D. Brison","doi":"10.1002/9781118977231.CH8","DOIUrl":"https://doi.org/10.1002/9781118977231.CH8","url":null,"abstract":"","PeriodicalId":448661,"journal":{"name":"Clinical Reproductive Science","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128260252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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