{"title":"The Importance of Pharmaceutical Dosage Forms in Administration via Enteral Feeding Tubes","authors":"K. Demirkan, A. Ekincioğlu","doi":"10.4274/TYBDD.25348","DOIUrl":"https://doi.org/10.4274/TYBDD.25348","url":null,"abstract":"E-pos ta: kutay@hacettepe.edu.tr Tel.: +90 312 305 10 88 ÖZ Ağızdan beslenmeyen hastaların kalori gereksinimleri, enteral veya parenteral beslenme ile desteklenmektedir. Gastrointestinal fonksiyon bozukluğu olmayan hastalarda öncelikle enteral beslenme tercih edilmektedir. Enteral beslenme, hastanın yutma eylemini gerçekleştiremediği durumlarda ilaç uygulanması amacıyla da kullanılmaktadır. Fakat beslenme tüpünden ilaç uygulanması karmaşık bir yoldur. Beslenme tüpünde tıkanmayı ve ilaç etkisinde azalmayı önlemek, ilaç toksisite riskini en aza indirebilmek için, ilaç uygulanması sırasında uygun tekniklerin kullanılması gerekmektedir. Ağızdan ilaç alamayan hastalarda, alternatif uygulama yolları olarak ilacın intravenöz, intramusküler, subkütan, inhale, transdermal, rektal yollar ve dil altı tabletler gibi farklı dozaj şekilleri mevcut olduğunda uygulamada öncelikle tercih edilmektedir. Alternatif uygulama yollarının elverişli olmadığı durumlarda, enteral beslenme tüpü ile ilaç uygularken Amerikan Parenteral ve Enteral Beslenme Derneği önerileri, beslenme tüpünün boyutunun etkisi, beslenme tüpünün konumunun etkisi, farmasötik dozaj şeklinin özellikleri ve uygulama yöntemleri göz önüne alınmalıdır. Nütrisyon desteği alan hastalarda ilaç etkileşimi olasılığı ortaya çıkmaktadır. Etkileşimleri önleyebilmek için ilacın mekanizması ve özellikleri konusunda daha detaylı eğitim alan bir eczacının ekipte olması ve mesleki bilgilerinden faydalanması gerekmektedir. Anahtar Kelimeler: Enteral beslenme, dozaj şekilleri, enteral ilaç uygulama SUMMARY A caloric requirement of the patients who do not have an access for feeding through an oral route is supported by enteral or parenteral nutrition. In the patients who have suitable gastrointestinal function, enteral feeding is preferred initially. Enteral feeding is also used for administration of medications in patients who cannot swallow. However, an administration of drugs via a feeding tube is complicated; appropriate techniques should be used in order to prevent obstruction of feeding tube and thereby avoid reduction of the drug effect and to minimize the risk of toxicity of given pharmaceuticals. In the patients who are not able to take medication orally, alternative routes such as intravenous, intramuscular, subcutaneous, inhaled, transdermal, rectal, and sublingual administrations are available and should be preferred at the first place. According to the American Society for Parenteral and Enteral Nutrition, an effect of a size and the position of the feeding tube, characteristics of pharmaceutical dosage form and methods of administration should be considered when applying medication via enteral tube. The risk of the drug interactions arises in patients who have nutritional support. In order to prevent drug interactions, a pharmacist, who has an extensive education and knowledge on drugs, its characteristics and mechanism of action is required for multidisciplinary team in clinical practice.","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117229640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uğur Altınışık, H. B. Altinişik, T. Şimşek, Tuğba Doğu, Esen Şimşek, Halide Aydın
{"title":"Clinical Characteristics of Patients Diagnosed with Synthetic Cannabinoid (Bonsai) Intoxication in Intensive Care Unit","authors":"Uğur Altınışık, H. B. Altinişik, T. Şimşek, Tuğba Doğu, Esen Şimşek, Halide Aydın","doi":"10.4274/TYBDD.36025","DOIUrl":"https://doi.org/10.4274/TYBDD.36025","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116713484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aslı Hepkarşı, C. Bor, K. Demirag, Ilkin Cankayalı, M. Uyar
{"title":"The Comparison of Ramsay and Richmond Scales for Intensive Care Unit Sedation, the Consistency Between Doctors and Nurses","authors":"Aslı Hepkarşı, C. Bor, K. Demirag, Ilkin Cankayalı, M. Uyar","doi":"10.4274/TYBDD.20592","DOIUrl":"https://doi.org/10.4274/TYBDD.20592","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"120 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129206960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serap Süzük, Ç. Edis, A. Çalik, Serpil Akdoğan, S. Ünal
{"title":"The Compliance Rates of Hand Hygiene in Intensive Care Unit and Surgical Services at a State Hospital in Turkey","authors":"Serap Süzük, Ç. Edis, A. Çalik, Serpil Akdoğan, S. Ünal","doi":"10.4274/TYBDD.77699","DOIUrl":"https://doi.org/10.4274/TYBDD.77699","url":null,"abstract":"Healthcare-associated infections (HAIs) cause many problems as prolonged hospitalization, consumption of resources as well as increased morbidity and mortality, increasing cost and antimicrobial resistance. The protection methods are important in HAIs as well as other infection diseases (1). Hand hygiene practice is one of the most effective measures to prevent HAIs (2). Although hand hygiene is an effective and simple method, hand hygiene compliance among health care workers is very low (3). SUMMARY Objective: The most efficient and most cost effective method for preventing health care associated infections is hand hygiene. Although hand hygiene is the most effective and simple method, compliance rates are very low among health care workers. It was aimed to evaluate the rates of compliance of healthcare workers in a state hospital. Material and Method: In this study, totally 112 healthcare workers (31 doctors and 81 nurses) were evaluated with the 5-indication observation method in a period between January and July 2013. Results: A total of 754 (65.9%) out of 1.144 cases were resulted in accurate hand washing and hand-rubbing. When the intensive care unit and surgical clinics were evaluated together, it was found that hand hygiene compliance rates were 51.26% in 199 cases and 66.85% in 591 cases for doctors and nurses, respectively. Conclusion: Consequently, we think that preinformed observations are important training instruments for hand hygiene compliance.","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132719085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bagci, H. Yeter, Aydın Fırıncıoğlu, K. Erkalp, A. Alagol
{"title":"Central Venous Catheterization Complication: Delayed Diagnosis of Venous Perforation and Hemothorax","authors":"M. Bagci, H. Yeter, Aydın Fırıncıoğlu, K. Erkalp, A. Alagol","doi":"10.4274/tybdd.20591","DOIUrl":"https://doi.org/10.4274/tybdd.20591","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128564256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Noise Sources and Levels in Intensive Care Units","authors":"Emine Kol, Emine İlaslan, Serpil Ince","doi":"10.4274/tybdd.97659","DOIUrl":"https://doi.org/10.4274/tybdd.97659","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134344183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Canan Yılmaz, Derya Karasu, Seda Cansabuncu, Yılmaz Apaydın, Hasan Özal, Mine Aköz
{"title":"Isolated Cerebral Fat Embolism After Lower Extremity Fracture: Case Report","authors":"Canan Yılmaz, Derya Karasu, Seda Cansabuncu, Yılmaz Apaydın, Hasan Özal, Mine Aköz","doi":"10.4274/TYBDD.46330","DOIUrl":"https://doi.org/10.4274/TYBDD.46330","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126979210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Sevdi, Meltem Türkay, T. Totoz, S. Demirgan, M. Erol, Ali Özalp, K. Erkalp, A. Alagöl
{"title":"Critical Illness Polyneuromyopathy Developing After Diabetic Ketoacidosis in an Intensive Care Unit","authors":"M. Sevdi, Meltem Türkay, T. Totoz, S. Demirgan, M. Erol, Ali Özalp, K. Erkalp, A. Alagöl","doi":"10.4274/TYBDD.13008","DOIUrl":"https://doi.org/10.4274/TYBDD.13008","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116538166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Axillary Brachial Plexus Blockage in Treatment of Upper Extremity Ischemic Disorder in Critically Ill Patient: A Report of Two Cases","authors":"İ. Ceylan, N. Girgin, M. Kopan, A. Gurbet","doi":"10.4274/TYBDD.41636","DOIUrl":"https://doi.org/10.4274/TYBDD.41636","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"117 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130421047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Şen, B. Erdivanlı, Tolga Koyuncu, Abdullah Özdemir, H. Kazdal
{"title":"Anesthesiologists’ Choice of Nutritional Therapy of Intensive Care Patients: A Survey Study","authors":"A. Şen, B. Erdivanlı, Tolga Koyuncu, Abdullah Özdemir, H. Kazdal","doi":"10.4274/TYBDD.63634","DOIUrl":"https://doi.org/10.4274/TYBDD.63634","url":null,"abstract":"","PeriodicalId":448120,"journal":{"name":"Türk Yoğun Bakim Derneği Dergisi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116075866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}