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C63. MECHANISTIC STUDIES IN COPD最新文献

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Synthetic Liposome Mimics of Alveolar Macrophage-Derived Vesicles Containing Suppressor of Cytokine Signaling 3: Inhibitors of Lung Tumor Cell Expansion and Potential Therapeutic for Lung Cancer 含细胞因子信号3抑制因子的肺泡巨噬细胞衍生囊泡的合成脂质体模拟物:肺肿瘤细胞扩增的抑制剂和肺癌的潜在治疗方法
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7433
J. Speth, L. Penke, Joseph Bazzill, J. Moon, M. Peters-Golden
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引用次数: 0
Neutrophil Elastase Activates Macrophages via Integrin-Src Kinase Pathway 中性粒细胞弹性蛋白酶通过整合素src激酶途径激活巨噬细胞
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5385
G. Graves, K. Krotova, N. Khodayari, Regina A Oshins, G. Aslanidi, M. Brantly
{"title":"Neutrophil Elastase Activates Macrophages via Integrin-Src Kinase Pathway","authors":"G. Graves, K. Krotova, N. Khodayari, Regina A Oshins, G. Aslanidi, M. Brantly","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5385","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5385","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122814144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MicroRNA Regulation of Cell Fate in the Pathogenesis of COPD MicroRNA在COPD发病机制中调控细胞命运
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5375
M. Sauler, J. Nouws, W. Feng, P. Lee
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引用次数: 2
Extracellular Bronchoalveolar Lavage Fluid Ferritin and Risk for Exacerbation in COPD: An Analysis from the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS) 细胞外支气管肺泡灌洗液铁蛋白与COPD加重风险:COPD研究亚群和中间结局指标分析(SPIROMICS)
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5369
William Z. Zhang, C. Oromendia, Sarah Ann Kikkers, Kihwan Kim, W. O’Neal, C. Freeman, S. Christenson, S. Peters, J. Wells, C. Doerschuk, N. Putcha, P. Woodruff, C. Cooper, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, J. Curtis, R. Kaner, K. Ballman, F. Martinez, S. Cloonan, Spiromics
{"title":"Extracellular Bronchoalveolar Lavage Fluid Ferritin and Risk for Exacerbation in COPD: An Analysis from the Subpopulations and Intermediate Outcome Measures in COPD Study (SPIROMICS)","authors":"William Z. Zhang, C. Oromendia, Sarah Ann Kikkers, Kihwan Kim, W. O’Neal, C. Freeman, S. Christenson, S. Peters, J. Wells, C. Doerschuk, N. Putcha, P. Woodruff, C. Cooper, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, J. Curtis, R. Kaner, K. Ballman, F. Martinez, S. Cloonan, Spiromics","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5369","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5369","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132646668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The Effects of PDE4 Inhibitors Roflumilast and CHF6001 on Cytokine Production from COPD BAL Lymphocytes PDE4抑制剂罗氟米司特和CHF6001对COPD BAL淋巴细胞细胞因子产生的影响
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5387
S. Lea, L. Hodgson, T. Southworth, F. Facchinetti, G. Villetti, M. Civelli, D. Singh
{"title":"The Effects of PDE4 Inhibitors Roflumilast and CHF6001 on Cytokine Production from COPD BAL Lymphocytes","authors":"S. Lea, L. Hodgson, T. Southworth, F. Facchinetti, G. Villetti, M. Civelli, D. Singh","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5387","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5387","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131230448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Circulating Cell-Free Mitochondrial DNA to Outcomes in COPD in the SPIROMICS Cohort SPIROMICS队列中循环无细胞线粒体DNA与COPD预后的关系
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7430
K. Schiffer, M. Rice, C. Oromendia, William Z. Zhang, S. Peters, P. Woodruff, C. Cooper, R. Bowler, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, R. Barr, J. Krishnan, M. Dransfield, J. Curtis, K. Ballman, F. Martinez, K. Nakahira, S. Cloonan, M. E. Choi, A. Choi, Spiromics
{"title":"Association of Circulating Cell-Free Mitochondrial DNA to Outcomes in COPD in the SPIROMICS Cohort","authors":"K. Schiffer, M. Rice, C. Oromendia, William Z. Zhang, S. Peters, P. Woodruff, C. Cooper, R. Bowler, A. Comellas, G. Criner, R. Paine, N. Hansel, M. Han, R. Barr, J. Krishnan, M. Dransfield, J. Curtis, K. Ballman, F. Martinez, K. Nakahira, S. Cloonan, M. E. Choi, A. Choi, Spiromics","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7430","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7430","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123599730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Role of Human SP-D Genetic Variants in the Pathogenesis of Chronic Lung Injury 人SP-D基因变异在慢性肺损伤发病机制中的作用
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5372
L. Ni
{"title":"Role of Human SP-D Genetic Variants in the Pathogenesis of Chronic Lung Injury","authors":"L. Ni","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5372","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5372","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123795338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum Levels of the COPD-Biomarker sRAGE Strongly Correlate with Specific Phenotypes and the Progression of Emphysema copd生物标志物sRAGE的血清水平与特定表型和肺气肿的进展密切相关
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5371
S. D. Pouwels, F. Klont, M. Kwiatkowski, J. Charbonnier, E. V. Rikxoort, R. Bowler, R. Bischoff, N. T. Hacken
{"title":"Serum Levels of the COPD-Biomarker sRAGE Strongly Correlate with Specific Phenotypes and the Progression of Emphysema","authors":"S. D. Pouwels, F. Klont, M. Kwiatkowski, J. Charbonnier, E. V. Rikxoort, R. Bowler, R. Bischoff, N. T. Hacken","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5371","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5371","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114211428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nontypeable Haemophilus Influenzae (NTHi) Exploits Disease-Related Defects in Xenophagy to Persist and Traffic Within the Epithelial Compartment During COPD 非分型流感嗜血杆菌(NTHi)利用疾病相关的异种吞噬缺陷在慢性阻塞性肺病期间持续存在并在上皮间室内交通
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5376
E. Roscioli, M. Poh, A. Kicic, S. Lester, Phan T Nguyen, H. Jersmann, P. Reynolds, S. Hodge
{"title":"Nontypeable Haemophilus Influenzae (NTHi) Exploits Disease-Related Defects in Xenophagy to Persist and Traffic Within the Epithelial Compartment During COPD","authors":"E. Roscioli, M. Poh, A. Kicic, S. Lester, Phan T Nguyen, H. Jersmann, P. Reynolds, S. Hodge","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5376","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A5376","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129453501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nicotine Plays a Key Role on Inflammation Driven by Monocyte-Derived-Macrophages of Subjects with Alpha-1 Antitrypsin Deficiency 尼古丁在α -1抗胰蛋白酶缺乏症患者单核细胞衍生巨噬细胞驱动的炎症中起关键作用
C63. MECHANISTIC STUDIES IN COPD Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7431
L. Benninger, J. Lee, K. Krotova, J. West, J. Lascano, M. Brantly
{"title":"Nicotine Plays a Key Role on Inflammation Driven by Monocyte-Derived-Macrophages of Subjects with Alpha-1 Antitrypsin Deficiency","authors":"L. Benninger, J. Lee, K. Krotova, J. West, J. Lascano, M. Brantly","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7431","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7431","url":null,"abstract":"","PeriodicalId":448051,"journal":{"name":"C63. MECHANISTIC STUDIES IN COPD","volume":"124 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125118512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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