Journal of Cardiology & Cardiovascular Therapy最新文献_第3页

Augmentation of Zinc Concentration in Blood has a Favorable Effect on Cardiac Function Post-Myocardial Infarction 提高血液中锌的浓度对心肌梗死后的心功能有好处

Journal of Cardiology & Cardiovascular Therapy Pub Date : 2020-04-27 DOI: 10.19080/jocct.2020.16.555933

R. Aikawa

{"title":"Augmentation of Zinc Concentration in Blood has a Favorable Effect on Cardiac Function Post-Myocardial Infarction","authors":"R. Aikawa","doi":"10.19080/jocct.2020.16.555933","DOIUrl":"https://doi.org/10.19080/jocct.2020.16.555933","url":null,"abstract":"Background: We have recently reported that polaprezinc which is a zinc delivery has an anti-inflammatory effect and improves cardiac function after acute myocardial infarction (AMI). As a secondary analysis, the aim of the present study was to evaluate if zinc concentration in blood affects anti-inflammatory effect and cardiac function after AMI. Methods: The primary study population included 50 patients with AMI. We equally divided the patients into two groups between the high group (H) and the low group (L) by blood concentration of zinc without relating to polaprezinc medication. The two groups were analyzed about cardiac function, cardiac enzymes, and the levels of the inflammation marker interleukin-6 (IL-6) as similar to the primary study. Results: The urine zinc levels of the H group were prominently higher than those of the L group at 8 days after PCI. The mean IL-6 level was strongly reduced in the H group (44.7(7.15-107.7) pg/mL vs. 130(19.6-384.25) pg/mL, respectively; p<0.05). As for the days of decline of both CRP and WBC, there were significant differences between the two groups (Figure 2). In addition, echocardiography indicated that the EF of the H group was clearly increased between day 3 and 9 months post-MI (54.5(50.5-59.75)% vs. 62(55-70)%, respectively; p<0.01). Conclusions: The present study suggests that high concentration of zinc has an anti-inflammatory effect and improves cardiac function after AMI.","PeriodicalId":447476,"journal":{"name":"Journal of Cardiology & Cardiovascular Therapy","volume":"140 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141209823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intravascular Ultrasound (IVUS) for Deep Venous Work - Want or Need? 用于深静脉工作的血管内超声 (IVUS) - 想要还是需要？

Journal of Cardiology & Cardiovascular Therapy Pub Date : 2020-04-02 DOI: 10.19080/jocct.2020.16.555931

TY Tang

引用次数: 1

Hypertension and Emergency Department Visits by Patients with Head and Neck Cancer 高血压与头颈部癌症患者的急诊就诊率

Journal of Cardiology & Cardiovascular Therapy Pub Date : 2020-03-30 DOI: 10.19080/jocct.2020.15.555929

Cielito C Reyes Gibby

{"title":"Hypertension and Emergency Department Visits by Patients with Head and Neck Cancer","authors":"Cielito C Reyes Gibby","doi":"10.19080/jocct.2020.15.555929","DOIUrl":"https://doi.org/10.19080/jocct.2020.15.555929","url":null,"abstract":"Background: The Emergency Department (ED) is the safety net for unanticipated or undertreated health needs. Patients with cancer have been reported to be substantial users of ED resources, to be of higher acuity than others, and to have a longer length of stay. Patients with head and neck cancer live longer than patients with other types of cancer. Therefore, we assessed the extent to which epidemiological, behavioral, and clinical factors collected prior to treatment were associated with eventual ED visits in patients with head and neck cancer. Methods: Questionnaires were administered at baseline, prior to cancer treatment. ED data were abstracted for up to 5 years follow up period from initial diagnosis and treatment of patients newly diagnosed with squamous cell carcinoma of the head and neck (HNSCC). Results: Our sample comprised 969 patients. The earliest ED visit occurred within 1 week of diagnosis. As many as 513 patients had ≥1 ED visit and the mean time to first ED visit was 27 weeks (SD=2.3 weeks). The most frequent chief complaints were: pain (n=181; 35.3% [abdominal pain=16.3%, chest pain=7.5%]); fever (n=107; 20.9%); nausea/vomiting (n=64; 12.5%); weakness/fatigue (n=45; 8.8%). Multivariate logistic regression indicated that hypertension (OR=1.43, 95% CI=1.02–2.03; P=0.039), T-stage (OR=2.05, 95% CI=1.45–2.92; P<0.0001), and N-stage (OR=1.47, 95% CI=1.17–1.86; P<0.001) were significantly associated with ED visits. Conclusion: To our knowledge, our study is the first to find a specific association between hypertension and ED visits in patients with HNSCC. Further research is needed to investigate possible reasons for the association between comorbidities such as hypertension and the need for emergent care, as well as to determine whether aggressive management of comborbid conditions during and after cancer therapy might reduce the likelihood of ED visits.","PeriodicalId":447476,"journal":{"name":"Journal of Cardiology & Cardiovascular Therapy","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141220023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac Tamponade Due to Primary Hypothyroidism: A Rare Presentation 原发性甲状腺功能减退症导致的心脏填塞：罕见病例

Journal of Cardiology & Cardiovascular Therapy Pub Date : 2020-03-30 DOI: 10.19080/jocct.2020.16.555930

Hind Tahri

引用次数: 0

Journal of Cardiology &amp; Cardiovascular Therapy最新文献

Journal of Cardiology & Cardiovascular Therapy最新文献