{"title":"STUDY OF THE INFLUENCE OF NATURAL IONIZING RADIATION COMBINED WITH TECHNOGENIC ON RED BLOOD INDICATORS","authors":"Kovalenko P. H.","doi":"10.32999/ksu2524-0838/2022-32-2","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2022-32-2","url":null,"abstract":"","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131627100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CORM-2 AFFECTS LEVEL OF MALONDIALDEHYDE AND EXPRESSION OF MYOCARDIAL MARKERS PTGS2, ANP, BNP, MVH7 UNDER INDUCED FERROPTOSIS","authors":"Beschasnyi S. P.","doi":"10.32999/ksu2524-0838/2022-32-5","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2022-32-5","url":null,"abstract":"","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128648950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"SYNTAXONOMY OF VEGETATION OF NATIONAL NATURE PARK «DZHARYLHATSKYI». THE CLASS JUNCETEA MARITIMI","authors":"Davydovа А. О.","doi":"10.32999/ksu2524-0838/2022-32-6","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2022-32-6","url":null,"abstract":"","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128956403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Prokopiak M. Z., Holinei H. M., Kryzhanovska M. A.
{"title":"ANALYSIS OF THE INVASION OF THE WESTERN CORN ROOTWORM IN THE KHMELNYTSKYI REGION","authors":"Prokopiak M. Z., Holinei H. M., Kryzhanovska M. A.","doi":"10.32999/ksu2524-0838/2022-32-4","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2022-32-4","url":null,"abstract":"","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123342154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"FINDINGS OF SEVERAL ALIEN VASCULAR PLANTS IN POLTAVA REGION","authors":"Davydov D. A.","doi":"10.32999/ksu2524-0838/2022-32-1","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2022-32-1","url":null,"abstract":"","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115796833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CHARACTERISTICS OF THE FUNCTIONAL STATE OF THE RESPIRATORY SYSTEM OF CHILDREN 9-14 YEARS OLD","authors":"Kots S. M., Kots V. P., Kovalenko P. H.","doi":"10.32999/ksu2524-0838/2022-32-3","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2022-32-3","url":null,"abstract":"","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122087105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"DYNAMICS OF THE FUNCTIONAL STATE OF THE CARDIOVASCULAR SYSTEM OF SCHOOL-AGE CHILDREN UNDER THE INFLUENCE OF A CORRECTIVE COMPLEX","authors":"Kots S.N., Kots V.P., Kovalenko P.G.","doi":"10.32999/ksu2524-0838/2021-31-4","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2021-31-4","url":null,"abstract":"The purpose of the work was to determine the functional state of the cardiovascular system of children of different ages,to determine the nature of the influence of the complex of respiratory and motor exercises and the intake of bee bread on the functional state of the cardiovascular system. Schoolchildren of 8-16 years old took part in the research. Materials and methods:anthropometric instrumental methods for the study of the cardiovascular system were used, the physiological index of regulation of the cardiovascular system -Robinson's index was determined. It was revealed that the studied schoolchildren of middle and senior school age have negative indicators of the level of regulation of the cardiovascular system -the level is below average. Strongly expressed dominance of the sympathetic system is observed in 3.8%, 48.2%, and 27.3% of children of different age groups. When comparing the groups, it can be noted that the indicators of the functional state of the cardiovascular system in the group of middle school age were the worst. The study shows that a complex with the inclusion of respiratory and motor exercises andbee bread (a special product made from pollen and honey) brings about positive changes in the functional state of the cardiovascular system. The reliability of the difference in systolic blood pressure at the beginning of the study and at the end was revealed in all age groups of the studied. During the study period in all three groups, there is a tendency to improve the regulation of the activity of the cardiovascular system. It was found that there were positive changes in the indicators of the functional state of the cardiovascular system of children of different ages. The results were taken into account for the development of health-improving and educational recreation programs in the camp to improve the indicators of the functional state of the circulatory system, regulate the activity of the cardiovascular system, and adapt capabilities.In order to improve the functional state of the respiratory system of schoolchildren, it is necessary to reduce the impact of hypodynamia, develop and implement the health programs and health technologies.Key words:functional assessment, cardiovascular system, children's health, regulation of cardiovascular system, hemodynamic parameters. Метою роботи було визначити функціональний стан серцево-судинної системи дітей різного віку, визначити характер впливу комплексу дихально–рухових вправ та прийому перги на функціональний стан серцево-судинної системи. В досліджені прийняли участь школярі 8-16 років.Буловикористано антропометричні інструментальні методи дослідження серцево-судинної системи, визначали фізіологічний індекс регуляції діяльності серцево-судинної системи –індекс Робінсона. Виявлено, що удосліджених школярів середнього та старшого шкільного віку відмічаються негативні показники рівня регуляції серцево-судинної системи –рівень нижче за середній. Сильно виражене домінування симпат","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116081933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"EFFECTS OF TESTOSTERONE ON BILE ACID COMPOSITION OF BILE RATS","authors":"Lupaina I.S., Liashevych A.M., Veselsky S.P.","doi":"10.32999/ksu2524-0838/2021-31-5","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2021-31-5","url":null,"abstract":"The study of sexual differences in the regulation of biliary secretory function of the liver is considered as one of the areas in hepatology. After all, the liver plays a role in mediating a number of systemic effects of sex hormones on the body and is a key organ of their metabolism. In particular, the correlation between the concentrations of sex hormones can determine the direction of physiological processes and their possible violations. Since hormones of a steroidal nature are considered to be one of the chains of effector mechanisms by which homeostasis is provided and processes of tissue proliferation, differentiation and growth occur, the correlation between the concentrations of steroid hormones can determine the direction of physiological processes and their possible disorders. The effects of androgens on cholate secretion remain poorly studied. Given the significant intersex differences in bile formation and bile secretion, the purpose of the study was to investigate the role of testosterone in the regulation of bile secretory function of the liver of female rats. During the study, physiological methods were used (surgery, cannulation of the bile ducts, registration of the dynamics of bile secretion); biochemical methods (separation by thin layer chromatography of the main organic components of bile (bile acids and lipids (cholesterol, cholesterol esters, phospholipids, triglycerides, free fatty acids)) with their preliminary differential extraction and subsequent quantitative densitometric evaluation of individual components of this bioliquid on chromatograms; methods of mathematical statistics (using the software package Statistica 5.0). Cholic secretion in female rats increased under the influence of testosterone. Testosterone increased the concentrations of taurocholic, tauroсhenodeoxycholic and taurodeoxycholic and glycocholic acids. Instead, the content of glycoсhenodeoxycholic and glycodeoxycholic acids under the action of testosterone decreased significantly, and the concentration of free bile acids -cholic, chenodeoxycholic and deoxycholic acids increased. As the content of taurocholate and glycocholate increased in female rats underthe influence of intraportal testosterone, this indicates an increase in the efficiency of the processes that provide conjugation and transformation of bile acids in the liver of these animals.Key words:testosterone propionate, cholates, free bile acids, conjugated bile acids, liver. Дослідження статевих відмінностей у регуляції жовчносекреторної функції печінки розглядається як один із напрямків у гепатології. Адже печінка відіграє роль посередника в ряді системних впливів статевих гормонів на організм і є ключовим органом їх обміну. Зокрема, співвідношення між концентрацією статевих гормонів може визначати направленість фізіологічних процесів та можливі їх порушення. Стероїдні гормони вважаються одними з ланцюгів тих ефекторних механізмів, за допомогою яких забезпечується гомеостаз та відбуваютьс","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"286 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132088771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BLOCKERS OF AQUAPORIN CHANNELS AND CARBON MONOXIDE INFLUENCE THE MYOCARDIUM IN CONDITIONS OF ISCHEMIA-REPERFUSION","authors":"B. S.P., Hasiuk O.M.","doi":"10.32999/ksu2524-0838/2021-31-1","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2021-31-1","url":null,"abstract":"Functioning of the cardiovascular system is provided by ion and aquaporin channels. Their disfunction cause damage to the whole body, reducing working efficiency and quality of life. Ischemia is the main factor affecting damage to the cardiovascular system. Myocardial reperfusion is often accompanied by negative processes, interstitial and cellular edema occurs. Water transport in thetissues of the cardiovascular system is provided by special channels called aquaporins. They also transport glycerol, urea and ammonia. The possibility of controlled exposure to these channels is an important target for the development of drugs that reduce ischemia-reperfusion injury. Carbon monoxide and anticonvulsants (lamotrigine and valproates) deserve special attention as blockers of aquaporin channels.The studies were performed on laboratory mice, which were divided into 5 groups. The first group was control; mice of the second-fourth groups were injected through a probe with phenytoin, lamotrigine, and topiramate, respectively. In the fifth group, a perfusion solution was passed through the isolated heart during perfusion, which was saturated with CO for 30 min. To study coronary flow, metabolic changes and individual indicators of electrical activity, we used retrograde perfusion technique of isolated heart on which ischemia and reperfusion were simulated. Phenytoin, lamotrigine, and CO were found to have vasodilator properties, however topiramate had a vasoconstrictor effect. Lamotrigine reduced glucose absorption during perfusion, phenytoin and topiramate –at the end of reperfusion, and CO –during reperfusion. Са2+depositing was found in the group that received phenytoin. In the group with lamotrigine and topiramate, the depositing was at the beginning of reperfusion. The use of perfusion solution with CO conditioned Са2+accumulation only at the end of reperfusion. Increased creatinine production was observed only in the groups that received phenytoin and topiramate. Aspartate aminotransferase levels were increased only in the group with lamotrigine at the time before ischemia. Anticonvulsants and CO, during perfusion, decreased the amplitude ofthe R waveform, whereas during ischemia, on the contrary, there was an increase in voltage. R-R interval shortening occurred only in the group with phenytoin. Lamotrigine and topiramate lengthened the interval, CO shortened the interval during reperfusion. Thus, the effects on aquaporin channels led to changes in coronary flow, glucose metabolism, and myocardial calcium depositing, and also the extent of myocardial damage during ischemia-reperfusion was reduced.Key words:aquaporins, valproates, gas-transmitter, myocardium, cardiac perfusion. Функціонування серцево-судинної системи забезпечується роботою йонних та аквапоринових каналів. Порушенняу їх роботі завдають шкоди усьому організму, знижуючи працездатність та якість життя. Основним чинником ушкоджувального впливу у серцево-судинній системі є ішемія. Реперфузія ","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"10 11","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114044191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"NON-SPECIFIC REACTIVITY OF HENS’ ORGANISM UNDER THE INFLUENCE OF THE GROUP SIZE CHANGE","authors":"Osadcha Yu. V.","doi":"10.32999/ksu2524-0838/2021-31-6","DOIUrl":"https://doi.org/10.32999/ksu2524-0838/2021-31-6","url":null,"abstract":"The parameters of the group size of laying hens in cages are not provided by current domestic standards, and according tothe recommendations of the cross-country developer should contain at least 7 birds, but in practice they reach 100 birds, so they need to be clarified when using 12-tier cage batteries of the classical constructions. The purpose of the research was to study the nonspecific reactivity of the hens' body under the influence of the group size with the same stoking density of laying hens in similar cages by design. To do this, 4 groups of hens were formed in the conditions of a modern complex for the eggs production, each of which was kept in a separate poultry house similar in area and equipment, equipped with 12-tier cage batteries, the size of the cages in which varied. The group size of hens in each cage of the 1stgroup was 93 birds, the 2nd–52 birds, the3rd–17 birds and 4th–9 birds. At 52 weeks of age, 30 blood samples were taken from each group of hens and a hemogram was determined. Integral immunohematological indices were calculated based on the hemogram. It was found that with a decrease in thegroup size of hens there is an increase in the shift indices of leukocytes, heterophiles to lymphocytesratio, immunoreactivity, heterophiles to monocytes ratio, lymphocytes to monocytesratio, lymphocytes to ESR ratio and lymphocytes to eosinophils ratio. This indicates a shift of the leukocyte formula to the left, the predominance of nonspecific protective cells due to a functional increase in bone marrow proliferative activity and is expressed in increased heterophiles, increased activity in the microphage-macrophage immune response system and indicates the presence of high levels of endogenic intoxication in the body of hens and impaired immunological reactivity, and can inform about the autoimmune nature of the pathological process. At the same time, a decrease in lymphocyte-granulocyteratio, total and lymphocyte indices was detected, which confirms the shift of the leukocyte formula to the left and indicates the dominance of cell activation of the immune system, indicates an active adaptive response of white blood. Simultaneous increase in the leukocyte shift index and decrease in the lymphocyte-granulocyte index indicates the development of endogenous intoxication in hens and impaired immunological reactivity due to autointoxication of the body during the destruction of its own cells. Key words: immunohematological indices, hens, stress, nonspecific reactivity, endogenous intoxication. Параметри величини угрупування курей-несучок промислового стада в клітках не передбачені діючими вітчизняними нормами, а за рекомендаціями розробника кросу мають становити не менше 7 гол., однак на практиці досягають 100 гол., тому потребують уточнення під час використання 12-ярусних кліткових батарей класичних конструкцій. Метою роботи було дослідження неспецифічної реактивності організму курей за впливу величини угрупування зоднаковою щільності п","PeriodicalId":445435,"journal":{"name":"Scientific Bulletin of Natural Sciences (Biological Sciences)","volume":"5 2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133617171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}