Journal of Clinical and Analytical Medicine最新文献

{"title":"Neutrophil/lymphocyte and platelet/lymphocyte ratios are associated with disease activity in rheumatoid arthritis","authors":"Senem Şaş","doi":"10.4328/JCAM.5939","DOIUrl":"https://doi.org/10.4328/JCAM.5939","url":null,"abstract":"DOI: 10.4328/JCAM.5939 Received: 18.06.2018 Accepted: 04.07.2018 Published Online: 09.07.2018 Printed: 01.05.2019 J Clin Anal Med 2019;10(3): 379-83 Corresponding Author: Senem Şaş, Kervansaray District. 2019 St. No:1 Kirsehir, Turkey. T.: +90 3862134515-1169 E-Mail: senemsas@gmail.com ORCID ID: 0000-0002-5616-5723 Abstract Aim: The aim of this study is to determine the relationship between Neutrophil to Lymphocyte (NLR) and Platelet to Lymphocyte (PLR) ratios in patients with Rheumatoid Arthritis (RA) and Disease Activity Score-28 (DAS28) and Rheumatoid Arthritis Quality of Life (RAQoL). Material and Method: One hundred twentyfive RA patients and 105 healthy controls were enrolled in the study. Patients were assessed and PLR, NLR, and DAS28, RAQoL values were calculated. Disease activity was calculated by DAS28 and quality of life was examined by RAQoL, HAQ (Health Assessment Questionnaire). Results: NLR (2,4 ± 1,9) and PLR (155,2 ± 82,3) value was significantly higher (p < 0.05) in RA. Positive correlation was observed between the two groups between DAS 28 with age, morning stiffness, VAS pain assessment, RF, ESR, CRP,NLR , PLR and swollen and tender joint number (p < 0.05) Significant negative correlation was observed between DAS 28 and hemoglobin, RBC, lymphocyte, monocyte % value (p < 0.05). There was no significant correlation between DAS28 and RAQoL, HAQ (p>0,05). Discussion: This study presents that NLR and PLR are associated with disease activity in patients with RA. NLR and PLR values can be assessed as an additional inflammatory marker in patients with RA.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41251319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of qSOFA criteria in prediction of poor prognosis in acute pancreatitis","authors":"M. C. Goktekin","doi":"10.4328/JCAM.6151","DOIUrl":"https://doi.org/10.4328/JCAM.6151","url":null,"abstract":"DOI: 10.4328/JCAM.6151 Received: 02.01.2019 Accepted: 14.01.2019 Published Online: 16.01.2019 Printed: 01.05.2019 J Clin Anal Med 2019;10(3): 398-401 Corresponding Author: Mehmet Cagri Göktekin, Department of Emergency Medicine, Firat University School of Medicine, 23200, Elazig, Turkey. T.: +90 4242370000/1231 E-Mail: dr23mcg@gmail.com ORCID ID: 0000-0001-7911-8965 Abstract Aim: In this study,we aimed to investigate the usability of SOFA and qSOFA criteria in predicting the conditions by which the poor prognosis such as hospitalization in the intensive care unit, long length of hospital stay and death was observed for the patients receiving a diagnosis of acute pancreatitis in the emergency department. Material and Method: The data of 98 patients with acute pancreatitis diagnosis which was verified by the computerized abdominal tomography in the university hospital emergency department between 2013 and 2018 were used in our study. that was designed as monocenteric retrospective study. The SOFA and qSOFA criteria of the patients were calculated during the application to the emergency department. Results: Fifty-three percent (n=52) of the patients were female. Their age averages were 57.5±18.57/year. Forty-eight (%49.0) patients were detected to have any of the poor prognostic criteria. It was also detected that the qSOFA score of 17 (517.3) patients were 1 and above and the qSOFA score of 81 (582.7) patients was 0 during the application to the emergency department. The SOFA (p<0.001) and qSOFA (p=0.004) values were significantly different for the patients having the good prognosis and poor prognosis. When we take the Cut-off as > 0 for the qSOFA criteria, we determined the AUC as 0.641, Sensitivity as %39.58, Specificity as %86, and CI% as 0.538 to 0.735, and p=0.001, respectively. Discussion: The SOFA and qSOFA criteria used in order to predict the organ failure in the sepsis can be a scoring system that will be able to be used in predicting the poor prognosis in acute pancreatitis in the emergency department.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45525653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The results of arthroscopic treatment for talus osteochondral lesions","authors":"Azad Yıldırım","doi":"10.4328/JCAM.5919","DOIUrl":"https://doi.org/10.4328/JCAM.5919","url":null,"abstract":"DOI: 10.4328/JCAM.5919 Received: 04.06.2018 Accepted: 08.10.2018 Published Online: 09.10.2018 Printed: 01.05.2019 J Clin Anal Med 2019;10(3): 359-64 Corresponding Author: Azad Yıldırım Diyarlife Dağ Kapı, Diyarbakır Hospital, Diyarbakır, Turkey. E-Mail: yildirimazad@gmail.com ORCID ID: 0000-0001-7058-4476 Abstract Aim: Our aim is to share the mid-term results of debritment and marrow bone stimulation proccess in patients with talus OCD who did not respond to the conservative treatment. Material and Method: The patients with talus osteochondritis dissecans weretreated by arthroscopic debridement; and bone marrow stimulation was performed with Kwire. Twenty-sixof them formed the primary and 15 of them formed the revision group. Clinical assessment included the Ogilvie-Harris score and American Orthopaedic Foot & Ankle Society (AOFAS) ankle-hindfoot score. The defects were classified according to the system of Berndt and Harty. The lesion side, symptom time, trauma history, age-related complication, Ogilvie-Harris and AOFAS scores, follow-up period, and well-being condition of the groups were compared. Results: A total of 41 patients, 25 males and 16 females, with a mean age of 34.3 years (range 19-62), were included in the present study. Follow-up ranged from 23-73 month (mean 34,3). The individual analysis results showed that the pre-operative AOFAS scores were significantly different between the primary and the revision groups, while post-operative scores were not significantly different between the primary and therevision groups. For the whole group, the AOFAS skore was excellent in 9 patients, good in 25, fair in 6 and poor in one. In the primary group the AOFAS scores were good in 14 (54%), fair in four (15) and excellent in eight (31) patients, while in the revision group they were good in eleven (73%), fair in two (13%) and poor in one (7%) patient. The combined good and excellent scores were 85% for the primary group and 80% for the revision group. The mean AOFAS AHS score at the 12th month was 88.2 in the primary group and 82.8 in the revision group. Discussion: Arthroscopic curettage and bone marrow stimulating process is a viable method and recommended for both primary and revision treatment of an osteochonditis dissecans of the talus.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46408254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of using a larger port on reducing the complications of laparoscopic cholecystectomy: A randomized trial","authors":"O. Toktaş","doi":"10.4328/jcam.6150","DOIUrl":"https://doi.org/10.4328/jcam.6150","url":null,"abstract":"Osman Toktas1, Oztekin Cıkman1, Caghan Peksen1, Sadi Elasan2, Nurettin Yuzkat3 1Department of General Surgery, 2Department of Biostatistics, 3Department of Anesthesiology and Reanimation, Yuzuncu Yıl University, Faculty of Medicine, Van, Turkey Reducing the complications of laparoscopic cholecystectomy The effect of using a larger port on reducing the complications of laparoscopic cholecystectomy: A randomized trial","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47021835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum-prolactin levels in patients with vitiligo","authors":"E. Bozkurt","doi":"10.4328/JCAM.5910","DOIUrl":"https://doi.org/10.4328/JCAM.5910","url":null,"abstract":"Emel Çiçek Bozkurt1, Hüseyin Bozkurt2, Ali Yılmaz3, Damla Atacan4 1Department of Dermatology, Ministry of Health Sivas Numune Hospital, Sivas, 2Department of Neurosurgery, Cumhuriyet University, Sivas, 3Department of Neurosurgery, Ordu University Medical School, Ordu, 4Department of Dermatology, Ministry of Health Dışkapı Education and Research Hospital, Ankara Turkey Serum-prolactin and vitiligo Serum-prolactin levels in patients with vitiligo","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45016209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of jebsen-taylor hand function test for use in nursing students: close-future outlook","authors":"Aynaci Gulden","doi":"10.4328/jcam.5941","DOIUrl":"https://doi.org/10.4328/jcam.5941","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48009140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatitis C virus genotype distribution in Ordu province","authors":"M. Çalgın","doi":"10.4328/JCAM.5936","DOIUrl":"https://doi.org/10.4328/JCAM.5936","url":null,"abstract":"DOI: 10.4328/JCAM.5936 Received: 13.06.2018 Accepted: 12.07.2018 Published Online: 17.07.2018 Printed: 01.05.2019 J Clin Anal Med 2019;10(3): 372-5 Corresponding Author: Mustafa Kerem Calgin, Ordu Universitesi Egitim ve Arastirma Hastanesi, Bucak Mah. Nefsi Bucak Cad. 52200, Ordu, Turkey. T.: +90 4522250186 F.: +90 4522250190 GSM: +905054951766 E-Mail: mkcalgin@gmail.com ORCID ID: 0000-0003-4236-6177 Abstract Aim: It is important to increase the number of studies on genotype distributions from different centers and regions of the country in terms of identifying the HCV genotype distribution in the whole country in general and creating appropriate treatment algorithms. Our study aimed to identify the HCV genotype distribution in patients infected with HCV attending our hospital in Ordu Province in the Central Black Sea region. Material and Method: The study included a total of 196 patients whose samples were sent to our laboratory for HCV viral load measurements from January 2016 to May 2018 with HCV-RNA positivity identified. Genotype definition was completed with the real-time PCR method. Results: It was observed that 4 patients (2%) had genotype 1, 7 patients (3.6%) had genotype 1a, 179 patients (91.4%) had genotype 1b, 5 patients (2.5%) had genotype 3 and 1 patient (0.5%) had genotype 4. Discussion: The most common genotype observed among patients attending our hospital was genotype 1. Genotypes 3 and 4 were rarely observed in comparison to Turkish data, similar to other provinces in regions receiving little migration. As medication resistance and treatment failure is high for genotype 1, the risk of encountering treatment failure continues to be a serious problem in our region.","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47890519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of pressure- and volume-controlled one -lung ventilation on lung dynamics and plasma malondialdehy de level","authors":"Ozkan Yavuz","doi":"10.4328/JCAM.5884","DOIUrl":"https://doi.org/10.4328/JCAM.5884","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44453903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of data collected in the first stage within the scope of hemoglobinopathy control program in Turkey’s east mediterranean city Kahramanmaraş","authors":"F. Taş","doi":"10.4328/JCAM.5923","DOIUrl":"https://doi.org/10.4328/JCAM.5923","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43851496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of aerobic training on plasma leptin and pulmonary functions in obese adolescents","authors":"Salwa R. El-Gendy","doi":"10.4328/JCAM.5946","DOIUrl":"https://doi.org/10.4328/JCAM.5946","url":null,"abstract":"","PeriodicalId":44485,"journal":{"name":"Journal of Clinical and Analytical Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42178486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}