The American journal of cardiology最新文献

{"title":"Association Between Chronic Obstructive Pulmonary Disease and All-Cause Mortality After Aortic Valve Replacement for Aortic Stenosis.","authors":"R. Myagmardorj, T. Nabeta, K. Hirasawa, G. Singh, F. van der Kley, A. de Weger, N. Ajmone Marsan, Jeroen J. Bax, V. Delgado","doi":"10.1093/eurheartj/ehac544.127","DOIUrl":"https://doi.org/10.1093/eurheartj/ehac544.127","url":null,"abstract":"Chronic obstructive pulmonary disease (COPD) and aortic stenosis (AS) are the most common diseases in which age plays a major role in the increase of their prevalence and when they co-exist, the outcomes prognosis worsens significantly. The aim of the present study was to evaluate the association between pulmonary functional parameters and all-cause mortality after aortic valve replacement (transcatheter or surgical). A total of 400 patients with severe AS and preoperative pulmonary functional test were retrospectively analyzed. Echocardiography and pulmonary functional parameters before aortic valve replacement were collected. COPD severity was defined according to criteria from the Society of Thoracic Surgeons. COPD was present in 128 patients (32%) with severe AS. Patients without COPD had smaller left ventricular (LV) mass and LV end-systolic volume and better LV function than the group with COPD. During a median follow-up of 32 months, 92 patients (23%) died. The survival rates were significantly lower in patients with moderate and severe COPD (log-rank p = 0.003). In the multivariable Cox regression analysis, any grade of COPD was associated with an approximately 2-fold increased risk of all-cause mortality (hazard ratio 1.933; 95% confidence interval 1.166 to 3.204; p = 0.011 for mild COPD and hazard ratio 2.028; 95% confidence interval 1.154 to 3.564; p = 0.014 for moderate or severe COPD). In addition to other clinical factors, any grade of COPD was associated with 2-fold increased risk of all-cause mortality.","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128327798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Embolic and Bleeding Risk Scores in Patients With Atrial Fibrillation and Cancer.","authors":"S. Raposeiras-Roubín, E. Abu-Assi, Alvaro Marchán, Tamara Fernández-Sanz, C. Barreiro-Pardal, I. M. Pousa, P. D. Erquicia, Ana Ledo-Piñeiro, Inmaculada González-Bermúdez, María Melendo Viu, A. Iñíguez-Romo","doi":"10.2139/ssrn.4048766","DOIUrl":"https://doi.org/10.2139/ssrn.4048766","url":null,"abstract":"Little is known about the prediction of atrial fibrillation (AF) risk scores in patients with cancer. The aim of this study was to assess the predictive ability of the CHA2DS2-VASc and HAS-BLED scores in patients with AF and cancer. Overall, 16,056 patients with AF diagnosed between 2014 and 2018 from a Spanish health area, including 1,137 patients with cancer, were observed during a median follow-up of 4.9 years. Although discrimination was similar between patients with cancer and patients without cancer who were treated with anticoagulation therapy (0.56 and 0.58), in patients with cancer who were not treated with anticoagulation therapy, c-statistic of CHA2DS2-VASc was poor and significantly lower than in the patients without cancer (0.42 vs 0.65). The overall precision of the CHA2DS2-VASc score was good throughout the follow-up (Brier score < 0.1), in patients with and without cancer. Regarding the HAS-BLED score, calibration and discrimination were poor in patients with cancer (c-statistic 0.51), similar to those in patients without cancer (c-statistic 0.53). In patients with cancer who were not treated with anticoagulation therapy, the embolic risk CHA2DS2-VASc score = 1 was similar to CHA2DS2-VASc score ≥ 2. Only patients with AF and cancer and CHA2DS2-VASc score = 0 presented a low risk of embolic events (negative predictive value 100%). A HAS-BLED score > 3 was not associated with higher bleeding risk in patients with cancer (p > 0.05). In summary, in patients with cancer and with AF, neither the CHA2DS2-VASc score nor the HAS-BLED score was useful for predicting embolic and hemorrhagic events, respectively. However, a CHA2DS2-VASc score 0 is useful to identify patients with AF and cancer who are at low embolic risk.","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132389723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left Ventricular Assist Device in Patients With Alcohol Abuse or Illicit Drug Use.","authors":"V. Truong, G. Egnaczyk, T. O'Brien, T. Raymond, S. Gilardi, S. Shreenivas, Answini A Geoffrey, E. Chung","doi":"10.1016/j.amjcard.2022.05.001","DOIUrl":"https://doi.org/10.1016/j.amjcard.2022.05.001","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117671355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Frequency of Ventricular Tachyarrhythmia in Men-Versus-Women in Patients with Implantable Cardioverter-Defibrillator for Primary Prevention.","authors":"A. Ojo, A. Younis, S. Saxena, V. Kutyifa, A. Chen, S. McNitt, B. Polonsky, M. Aktas, David T. Huang, S. Rosero, H. Vidula, Alexander Diamond, Ramya Sampath, H. Klein, Hillel A. Steiner, W. Zareba, I. Goldenberg","doi":"10.1016/j.amjcard.2022.04.027","DOIUrl":"https://doi.org/10.1016/j.amjcard.2022.04.027","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"609 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119836859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Stratification of New Persistent Left Bundle Branch Block After Transcatheter Aortic Valve Implantation.","authors":"Takahiro Tsushima, A. Main, S. Al-Kindi, L. Dallan, H. Wheat, C. Baeza, M. Pelletier, M. Arruda, J. Mackall, Sergio G Thal, Yohei Ohno, K. Lee, Dimytri A Siqueira, T. Kaneko, M. Harloff, G. Costa, M. Barbanti, G. Attizzani","doi":"10.1016/j.amjcard.2022.03.053","DOIUrl":"https://doi.org/10.1016/j.amjcard.2022.03.053","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119005132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relation of Extracardiac Vascular Disease and Outcomes in Patients With Diabetes (1.1 Million) Hospitalized for Acute Myocardial Infarction.","authors":"Sedralmontaha Istanbuly, Andrija Matetić, D. J. Roberts, P. Myint, M. Alraies, H. V. Van Spall, M. Mohamed, A. Bharadwaj, M. Mamas","doi":"10.1016/j.amjcard.2022.04.005","DOIUrl":"https://doi.org/10.1016/j.amjcard.2022.04.005","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"488 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119731357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Small Valve Size on 1-Year Outcomes After Transcatheter Aortic Valve Implantation in Women (from the WIN-TAVI Registry).","authors":"C. Pivato, D. Cao, A. Spirito, S. Sartori, J. Nicolas, M. Chiarito, Clayton Sneyder, J. Mehilli, T. Lefévre, G. Stefanini, P. Presbitero, P. Capranzano, D. Tchétché, A. Iadanza, B. Vogel, G. Sardella, N. Van Mieghem, M. Nardin, A. Tavenier, E. Meliga, N. Dumonteil, C. Fraccaro, D. Trabattoni, G. Mikhail, Samin K. Sharma, M. C. Ferrer, C. Naber, P. Kievit, U. Baber, A. Petronio, M. Morice, A. Chieffo, G. Dangas, R. Mehran","doi":"10.1016/j.amjcard.2022.02.025","DOIUrl":"https://doi.org/10.1016/j.amjcard.2022.02.025","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"118444656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Outcomes of Mitral Valve Disease With Mitral Annular Calcification.","authors":"M. Fukui, J. Cavalcante, Aisha K. Ahmed, R. Bae, V. Bapat, M. Gössl, Santiago Garcia, M. Enriquez-Sarano, P. Sorajja","doi":"10.1016/j.amjcard.2022.03.041","DOIUrl":"https://doi.org/10.1016/j.amjcard.2022.03.041","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"119408035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of left atrial structure and function with cognitive function among adults with metabolic syndrome","authors":"Ines Gonzalez Casanova, Á. Alonso-Gómez, D. Romaguera, E. Toledo, E. Fortuny, L. López, R. Ramallal, J. Salas‐Salvadó, L. Tojal-Sierra, O. Castañer, Alvaro Alonso","doi":"10.1101/2022.03.11.22272280","DOIUrl":"https://doi.org/10.1101/2022.03.11.22272280","url":null,"abstract":"Background: Atrial fibrillation has been associated with cognitive impairment. Whether subclinical abnormalities in atrial function and substrate predisposing to atrial fibrillation impact cognitive function has received limited attention. Methods: We tested associations of echocardiographic markers of atrial structure and function with cognitive functioning and decline among 510 participants with overweight/obesity and metabolic syndrome (mean age [standard deviation] of 64.4 [5.2] years in men and 66.5 [3.9] in women). Left atrial markers (volume index, emptying fraction, strain, function index, and stiffness index) were estimated based on transthoracic echocardiography. General cognitive functioning (Mini-mental examination), verbal ability (verbal fluency test), memory and attention (Digit Span Tests), and processing speed and executive function (Trail-Making Tests A and B) were assessed at baseline and at the two-year follow-up. Multiple linear regression was used to test associations of atrial markers (modeled in standard deviation units) with baseline and two-year changes in cognitive scores adjusting for demographic and health covariates. Results: Left atrial structure and function was not associated with cognitive function at baseline. Larger left atrial volume index (standardized {beta} [95% confidence interval] = -0.13 [-0.22, -0.03]), lower peak longitudinal strain (-0.11 [-0.20, -0.01]), and higher stiffness index (-0.18 [-0.28, -0.08) were associated with 2-year worsening in Trail-Making Test A. Strain measurements were also associated with 2-year change in the Controlled Oral Word Association Test. Conclusion: Overall, adverse markers of left atrial structure and function were associated with 2-year detrimental executive function-related cognitive changes in a sample of participants at high risk for cardiovascular disease, highlighting left atrial substrate as a potential risk factor for cognitive decline and dementia.","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114407823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary Artery Calcium Scoring for Risk Assessment in Patients With Severe Hypercholesterolemia.","authors":"Tony Dong, N. Tashtish, I. Neeland, K. Nasir, S. Rajagopalan, S. Al-Kindi","doi":"10.1016/s0735-1097(22)02548-7","DOIUrl":"https://doi.org/10.1016/s0735-1097(22)02548-7","url":null,"abstract":"","PeriodicalId":443997,"journal":{"name":"The American journal of cardiology","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120843569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}