{"title":"Metastatic Prostate Cancer Manifesting as Cavernous Sinus Syndrome—Case Report and Review of the Literature","authors":"B. Kuiper, Aline Babikian, W. Delacruz","doi":"10.17925/OHR.2017.13.01.59","DOIUrl":"https://doi.org/10.17925/OHR.2017.13.01.59","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"13 1","pages":"59"},"PeriodicalIF":1.1,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Answer the Call: Virtual Migration in Indian Call Centers by Aimee Carrillo Rowe, Sheena Malhotra, Kimberlee Pérez (review)","authors":"A. LeBoeuf","doi":"10.5860/choice.51-4738","DOIUrl":"https://doi.org/10.5860/choice.51-4738","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"240 1","pages":"464 - 466"},"PeriodicalIF":1.1,"publicationDate":"2016-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71145369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Greater Than Equal: African American Struggles for Schools and Citizenship in North Carolina, 1919–1965. By Sarah Caroline Thuesen.","authors":"Anna F. Kaplan","doi":"10.1093/OHR/OHW062","DOIUrl":"https://doi.org/10.1093/OHR/OHW062","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"43 1","pages":"458 - 460"},"PeriodicalIF":1.1,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1093/OHR/OHW062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"61386568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Editor’s Introduction","authors":"Kathryn L. Nasstrom","doi":"10.1515/9781503611023-004","DOIUrl":"https://doi.org/10.1515/9781503611023-004","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"43 1","pages":"i - ii"},"PeriodicalIF":1.1,"publicationDate":"2016-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66841196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biosimilars in Oncology","authors":"A. Zelenetz","doi":"10.17925/OHR.2016.12.01.22","DOIUrl":"https://doi.org/10.17925/OHR.2016.12.01.22","url":null,"abstract":"The escalating cost of cancer care is placing an increasing burden on healthcare systems worldwide, largely a result of expensive biologic therapies. With the patents on many biologics expiring, interest in biosimilars is rising. Biosimilars of biologic agents used for cancer treatment and supportive care are making their appearance in the US; this article therefore aims to increase understanding of the biosimilars concept. Biosimilars are very comparable to their reference products, but because of their size and complexity, are not identical. However, the inherent structural differences between biologics and their reference products may not translate to clinically meaningful differences in efficacy and safety. Biosimilars offer potential cost savings but present a challenge in terms of establishing a regulatory pathway. Regulatory approval requires comparative analytical and clinical studies in order to characterize and demonstrate the absence of clinically meaningful differences between biosimilars and their reference products. Initial approval may not include interchangeability, as additional evidence may be required before a biosimilar can be designated interchangeable with its reference product. A framework for the approval of biosimilars was established by the European Medicines Agency (EMA) in 2006 with the first biosimilar approved in April, 2006. Thus, the experience in Europe provides valuable insights into the use of biosimilars. The widespread use of biosimilars has the potential to reduce healthcare expenditure, as well as improving patient access without compromising patient outcomes, but clinician education and acceptance is crucial.","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"12 1","pages":"22"},"PeriodicalIF":1.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67596990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Future of Melanoma Immunotherapy","authors":"N. Khushalani, V. Sondak","doi":"10.17925/OHR.2016.12.01.29","DOIUrl":"https://doi.org/10.17925/OHR.2016.12.01.29","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"12 1","pages":"29"},"PeriodicalIF":1.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer Stem Cells and Cancer Stem Cell Inhibitors in Gastrointestinal Cancers","authors":"J. Hubbard, A. Grothey","doi":"10.17925/OHR.2016.12.01.41","DOIUrl":"https://doi.org/10.17925/OHR.2016.12.01.41","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"12 1","pages":"41"},"PeriodicalIF":1.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An Exciting New Era in the Treatment of Myeloproliferative Neoplasms","authors":"N. Daver, R. Assi","doi":"10.17925/OHR.2016.12.02.71","DOIUrl":"https://doi.org/10.17925/OHR.2016.12.02.71","url":null,"abstract":"M yeloproliferative neoplasms (MPNs), including primary myelofibrosis and myelofibrosis (MF) evolving from a pre-existing MPN (post polycythemia veraand post essential thrombocythemia-myelofibrosis) are clonal hematopoietic stem cell disorders with heterogeneous symptoms, mutational profile, transformation risk and prognosis. Given the potentially chronic disease course, the goal of therapy in MF is to alleviate associated signs and symptoms, including reduction in spleen size, weight gain, improved performance status, and control of constitutional symptoms, leading to a prolonged survival and reduced transformation to leukemia.","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"12 1","pages":"71"},"PeriodicalIF":1.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathways Forward in Candidate Selection for Systemic Therapy in Invasive Urothelial Cancer of the Bladder","authors":"D. Sundi","doi":"10.17925/OHR.2016.12.01.49","DOIUrl":"https://doi.org/10.17925/OHR.2016.12.01.49","url":null,"abstract":"","PeriodicalId":44122,"journal":{"name":"Oral History Review","volume":"12 1","pages":"49"},"PeriodicalIF":1.1,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67597121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}