Acute and Critical Care最新文献

{"title":"\"Acute and Critical Care\" begins to request the inclusion of geographical regions in the titles.","authors":"Jaehwa Cho","doi":"10.4266/acc.2023.01039","DOIUrl":"https://doi.org/10.4266/acc.2023.01039","url":null,"abstract":"","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7a/4e/acc-2023-01039.PMC10497886.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10238558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A fatal case report of invasive pulmonary aspergillosis and mucormycosis coinfection in an immunocompetent patient with coronavirus disease 2019 in Korea.","authors":"Jin Hyoung Kim,&nbsp;Misung Kim,&nbsp;Soyeoun Lim,&nbsp;Sun Young Park,&nbsp;Yangjin Jegal,&nbsp;Taehoon Lee,&nbsp;Byung Ju Kang","doi":"10.4266/acc.2021.01340","DOIUrl":"https://doi.org/10.4266/acc.2021.01340","url":null,"abstract":"<p><p>Systemic glucocorticoid treatment is highly recommended in critically ill coronavirus disease 2019 (COVID-19) patients. However, secondary fungal infections are of concern in such patients. Here, we describe the first case of COVID-19-associated invasive pulmonary aspergillosis (CAPA) and COVID-19-associated mucormycosis (CAM) coinfection in a COVID-19 positive immunocompetent patient in Korea. A 69-year-old man was admitted to our hospital with COVID-19 pneumonia. He had no underlying comorbidities and was not taking medications. He received remdesivir, dexamethasone, and antibiotic therapy under mechanical ventilation. Although his condition improved temporarily, multiple cavities were observed on chest computed tomography, and Aspergillus fumigatus was cultured from tracheal aspiration culture. He was diagnosed with probable CAPA and received voriconazole therapy. However, his condition was not significantly improved despite having received voriconazole therapy for 4 weeks. After release from COVID-19 quarantine, he underwent bronchoscopy examination and was then finally diagnosed with CAPA and CAM coinfection on bronchoscopic biopsy. Antifungal treatment was changed to liposomal amphotericin B. However, his progress deteriorated, and he died 4 months after admission. This case highlights that clinical suspicion and active checkups are required to diagnose secondary fungal infections in immunocompetent COVID-19 patients who receive concurrent glucocorticoid therapy.</p>","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/14/4c/acc-2021-01340.PMC10497891.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10288871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of stored arterial versus venous blood collected using the acute normovolemic hemodilution method in coronary artery bypass grafting patients in Iran.","authors":"Mojtaba Mansouri,&nbsp;Alireza Yazdani,&nbsp;Gholamreza Masoumi,&nbsp;Mohsen Mirmohammadsadeghi,&nbsp;Amir Mirmohammadsadeghi","doi":"10.4266/acc.2022.01382","DOIUrl":"https://doi.org/10.4266/acc.2022.01382","url":null,"abstract":"<p><strong>Background: </strong>In the present study, arterial and venous blood was collected from patients who were candidates for elective coronary artery bypass grafting (CABG); the blood was stored for 28 days and cellular, biomechanical, and hematological changes in blood were compared to determine whether stored arterial blood is superior to stored venous blood.</p><p><strong>Methods: </strong>The present follow-up comparative study included 60 patients >18 years of age, with hemoglobin >14 mg/dl and ejection fraction >40% who were candidates for CABG. After induction of anesthesia, 250 ml of arterial or venous blood was drawn from patients (arterial blood group and venous blood group). Laboratory blood samples were taken at specified times from the collected blood and re-injected into the patients after CABG.</p><p><strong>Results: </strong>Significant differences were observed in pH, partial pressure of carbon dioxide (PCO2), partial pressure of oxygen (PO2), bicarbonate (HCO3), and glucose values at several time points between the groups. Other parameters such as urea and creatinine did not show any significant differences between the groups.</p><p><strong>Conclusions: </strong>Twenty-eight days of storage can have a negative effect on some of the cellular, biochemical, and hematological components of arterial and venous blood; however, the quality of stored arterial blood and venous blood does not differ significantly.</p>","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/79/ab/acc-2022-01382.PMC10497887.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10291478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of safety and efficacy between therapeutic or intermediate versus prophylactic anticoagulation for thrombosis in COVID-19 patients: a systematic review and meta-analysis.","authors":"Hyeon-Jeong Lee,&nbsp;Hye Jin Jang,&nbsp;Won-Il Choi,&nbsp;Joonsung Joh,&nbsp;Junghyun Kim,&nbsp;Jungeun Park,&nbsp;Miyoung Choi","doi":"10.4266/acc.2022.01424","DOIUrl":"https://doi.org/10.4266/acc.2022.01424","url":null,"abstract":"<p><strong>Background: </strong>Patients with coronavirus disease 2019 (COVID-19) infections often have macrovascular or microvascular thrombosis and inflammation, which are known to be associated with a poor prognosis. Heparin has been hypothesized that administration of heparin with treatment dose rather than prophylactic dose for prevention of deep vein thrombosis in COVID-19 patients.</p><p><strong>Methods: </strong>Studies comparing therapeutic or intermediate anticoagulation with prophylactic anticoagulation in COVID-19 patients were eligible. Mortality, thromboembolic events, and bleeding were the primary outcomes. PubMed, Embase, the Cochrane Library, and KMbase were searched up to July 2021. A meta-analysis was performed using random-effect model. Subgroup analysis was conducted according to disease severity.</p><p><strong>Results: </strong>Six randomized controlled trials (RCTs) with 4,678 patients and four cohort studies with 1,080 patients were included in this review. In the RCTs, the therapeutic or intermediate anticoagulation was associated with significant reductions in the occurrence of thromboembolic events (5 studies, n=4,664; relative risk [RR], 0.72; P=0.01), and a significant increase in bleeding events (5 studies, n=4,667; RR, 1.88; P=0.004). In the moderate patients, therapeutic or intermediate anticoagulation was more beneficial than prophylactic anticoagulation in terms of thromboembolic events, but showed significantly higher bleeding events. In the severe patients, the incidence of thromboembolic and bleeding events in the therapeutic or intermediate.</p><p><strong>Conclusions: </strong>The study findings suggest that prophylactic anticoagulant treatment should be used in patients with moderate and severe COVID-19 infection groups. Further studies are needed to determine more individualized anticoagulation guidance for all COVID-19 patients.</p>","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a6/34/acc-2022-01424.PMC10265420.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9642390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Risk factors for intensive care unit readmission after lung transplantation: a retrospective cohort study\".","authors":"Maida Qazi,&nbsp;Mahnoor Amin","doi":"10.4266/acc.2022.01214","DOIUrl":"https://doi.org/10.4266/acc.2022.01214","url":null,"abstract":"critical myopathy, impaired skeletal muscle oxidative capacity, and local wound complications due to continuous motion in the thoracic region or old age factors. One study of 700 lung transplant recipients found a 9.2% incidence of neurological complications including stroke and metabolic encephalopathy in the first 2 weeks posttransplantation. Also, a retrospective study revealed the 90-day mortality rate in patients with neurologic complications after lung transplantation to be 15% and only 4% among recipients who did not develop such complications [3]","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/12/acc-2022-01214.PMC10265424.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10173472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between positive end-expiratory pressure levels, central venous pressure, systemic inflammation and acute renal failure in critically ill ventilated COVID-19 patients: a monocenter retrospective study in France.","authors":"Pierre Basse,&nbsp;Louis Morisson,&nbsp;Romain Barthélémy,&nbsp;Nathan Julian,&nbsp;Manuel Kindermans,&nbsp;Magalie Collet,&nbsp;Benjamin Huot,&nbsp;Etienne Gayat,&nbsp;Alexandre Mebazaa,&nbsp;Benjamin G Chousterman","doi":"10.4266/acc.2022.01494","DOIUrl":"https://doi.org/10.4266/acc.2022.01494","url":null,"abstract":"<p><strong>Background: </strong>The role of positive pressure ventilation, central venous pressure (CVP) and inflammation on the occurrence of acute kidney injury (AKI) have been poorly described in mechanically ventilated patient secondary to coronavirus disease 2019 (COVID-19).</p><p><strong>Methods: </strong>This was a monocenter retrospective cohort study of consecutive ventilated COVID-19 patients admitted in a French surgical intensive care unit between March 2020 and July 2020. Worsening renal function (WRF) was defined as development of a new AKI or a persistent AKI during the 5 days after mechanical ventilation initiation. We studied the association between WRF and ventilatory parameters including positive end-expiratory pressure (PEEP), CVP, and leukocytes count.</p><p><strong>Results: </strong>Fifty-seven patients were included, 12 (21%) presented WRF. Daily PEEP, 5 days mean PEEP and daily CVP values were not associated with occurrence of WRF. 5 days mean CVP was higher in the WRF group compared to patients without WRF (median [IQR], 12 mm Hg [11-13] vs. 10 mm Hg [9-12]; P=0.03). Multivariate models with adjustment on leukocytes and Simplified Acute Physiology Score (SAPS) II confirmed the association between CVP value and risk of WRF (odd ratio, 1.97; 95% confidence interval, 1.12-4.33). Leukocytes count was also associated with occurrence of WRF in the WRF group (14 G/L [11-18]) and the no-WRF group (9 G/L [8-11]) (P=0.002).</p><p><strong>Conclusions: </strong>In mechanically ventilated COVID-19 patients, PEEP levels did not appear to influence occurrence of WRF. High CVP levels and leukocytes count are associated with risk of WRF.</p>","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f5/3c/acc-2022-01494.PMC10265416.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Septic shock due to invasive pulmonary aspergillosis without conventional risk factors.","authors":"Kyung Eun Shin,&nbsp;Shinhee Park,&nbsp;Ae-Rin Baek","doi":"10.4266/acc.2023.00437","DOIUrl":"https://doi.org/10.4266/acc.2023.00437","url":null,"abstract":"was drowsy, with blood pressure 69/37 mm Hg, heart rate 75 beats/min, respiratory rate 22 beats/min, body temperature 36.9 °C, and pulse oxygen saturation 60% at room air. Coarse breath sounds with crackles were heard in both lung fields. Concurrent with mechanical ventilation, adequate intravenous fluid and norepinephrine were administered. The initial serum lactate level was elevated to 2.5 mmol/L. Chest radiograph showed increased opacities mainly in the right lower lung field (Figure 1A). Chest computed tomography revealed multifocal nodules with surrounding ground-glass opacities (GGOs), the “halo sign” in underlying emphysematous lungs, and extensive consolidation with GGO in both lower lobes (Figure 2A and B). The initial white blood cell and absolute neutrophil counts were 3,110/μl and 2,430/μl, which increased to 8,430/μl and 6,830/μl on the second day, respectively. Non-specific erythematous bronchial mucosa with a large amount of thick, purulent sputum was observed on bronchoscopy","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/de/af/acc-2023-00437.PMC10265421.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9639406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and outcome of an acute kidney injuries in the polytrauma victims admitted at the apex trauma center in Dubai.","authors":"Bhushan Sudhakar Wankhade,&nbsp;Zeyad Faoor Alrais,&nbsp;Ghaya Zeyad Alrais,&nbsp;Ammar Mohamed Abdel Hadi,&nbsp;Gopala Arun Kumar Naidu,&nbsp;Mohammed Shahid Abbas,&nbsp;Ahmed Tarek Youssef Aboul Kheir,&nbsp;Hasan Hadad,&nbsp;Sundareswaran Sharma,&nbsp;Mohammad Sait","doi":"10.4266/acc.2023.00388","DOIUrl":"https://doi.org/10.4266/acc.2023.00388","url":null,"abstract":"Background Polytrauma from road accidents is a common cause of hospital admissions and deaths, frequently leading to acute kidney injury (AKI) and impacting patient outcomes. Methods This retrospective, single-center study included polytrauma victims with an Injury Severity Score (ISS) >25 at a tertiary healthcare center in Dubai. Results The incidence of AKI in polytrauma victims is 30.5%, associated with higher Carlson comorbidity index (P=0.021) and ISS (P=0.001). Logistic regression shows a significant relationship between ISS and AKI (odds ratio [OR], 1.191; 95% confidence interval [CI], 1.150–1.233; P<0.05). The main causes of trauma-induced AKI are hemorrhagic shock (P=0.001), need for massive transfusion (P<0.001), rhabdomyolysis (P=0.001), and abdominal compartment syndrome (ACS; P<0.001). On multivariate logistic regression AKI can be predicated by higher ISS (OR, 1.08; 95% CI, 1.00–1.17; P=0.05) and low mixed venous oxygen saturation (OR, 1.13; 95% CI, 1.05–1.22; P<0.001). The development of AKI after polytrauma increases length of stay (LOS)-hospital (P=0.006), LOS-intensive care unit (ICU; P=0.003), need for mechanical ventilation (MV) (P<0.001), ventilator days (P=0.001), and mortality (P<0.001). Conclusions After polytrauma, the occurrence of AKI leads to prolonged hospital and ICU stays, increased need for mechanical ventilation, more ventilator days, and a higher mortality rate. AKI could significantly impact their prognosis.","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f1/2b/acc-2023-00388.PMC10265426.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9642389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to \"Adjuvant intravenous immunoglobulin administration on postoperative critically ill patients with secondary peritonitis: a retrospective study\"","authors":"Young Un Choi,&nbsp;Jun Gi Kim,&nbsp;Ji Young Jang,&nbsp;Tae Hwa Go,&nbsp;Kwangmin Kim,&nbsp;Keum Seok Bae,&nbsp;Hongjin Shim","doi":"10.4266/acc.2022.01515.e1","DOIUrl":"https://doi.org/10.4266/acc.2022.01515.e1","url":null,"abstract":"","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e6/e3/acc-2022-01515-e1.PMC10265427.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9683291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to comment on \"Risk factors for intensive care unit readmission after lung transplantation: a retrospective cohort study\".","authors":"Hye-Bin Kim,&nbsp;Sungwon Na,&nbsp;Hyo Chae Paik,&nbsp;Hyeji Joo,&nbsp;Jeongmin Kim","doi":"10.4266/acc.2023.00556","DOIUrl":"https://doi.org/10.4266/acc.2023.00556","url":null,"abstract":"We appreciate Qazi and Amin [1] for their interest in our study [2]. We agree that a better prognosis for lung transplantation (LT) patients requires consideration and management of various perioperative factors. As noted in the Introduction section, we focused on the postoperative state of LT patients, showing substantial change due to surgery, rather than their preoperative condition. We assessed the patients’ baseline pulmonary function, educational level (as a proxy for socioeconomic status), and Eastern Cooperative Oncology Group performance status (a comprehensive measure of overall health status that incorporates the modified Medical Research Council dyspnea scale) to obtain a more complete understanding of their condition. However, we did not examine and document the patients’ muscle strength or emotional state between 2012 and 2017. We have recently evaluated and optimized measurement of patients’ physical and mental status with patient-centered techniques before and after surgery, as we recognize their crucial impact on prognosis [3]. Considering the possibility of various complications following LT, we acknowledge the importance of close observation and meticulous management, in conjunction with rehabilitation protocols. Since the introduction of LT, various rehabilitation programs have been implemented and refined. However, at the time of study performance, such programs were not fully established, and there were numerous missing data points regarding patients’ respiratory and physical status, which posed a challenge for our retrospective research. Nevertheless, we suggest that major postoperative complications occurring early after LT, which can significantly affect recovery trajectory, have been identified through causes of intensive care unit (ICU) readmission or in-hospital mortality, as presented in Figures 2 and 3 of our article [2]. Except for rejection, immunosuppressant-related infections, and rehabilitation issues, individualized measures for specific complications should be taken following LT, rather than relying solely on general treatment protocols for LT patients. LT recipients in our study were managed according to the established protocol, including immunosuppressive therapy with administration of tacrolimus, mycophenolate mofetil, and steroids. Antibiotics such as teicoplanin or vancomycin and cefepime were administered for 5 days after surgery to prevent bacterial infection. Ganciclovir, later switched to oral valganciclovir, to prevent cytomegalovirus infection and itraconazole to avoid fungal infecReply to comment on “Risk factors for intensive care unit readmission after lung transplantation: a retrospective cohort study”","PeriodicalId":44118,"journal":{"name":"Acute and Critical Care","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2e/04/acc-2023-00556.PMC10265422.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9642393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}