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Patient Preferences for Point-of-Care Testing: Survey Validation and Results. 患者对即时护理测试的偏好:调查验证和结果。
Point of Care Pub Date : 2020-12-01 DOI: 10.1097/poc.0000000000000214
Craig M Lilly, Emily Ensom, Sean Teebagy, Danielle DiMezza, Denise Dunlap, Nathaniel Hafer, Bryan Buchholz, David McManus
{"title":"Patient Preferences for Point-of-Care Testing: Survey Validation and Results.","authors":"Craig M Lilly,&nbsp;Emily Ensom,&nbsp;Sean Teebagy,&nbsp;Danielle DiMezza,&nbsp;Denise Dunlap,&nbsp;Nathaniel Hafer,&nbsp;Bryan Buchholz,&nbsp;David McManus","doi":"10.1097/poc.0000000000000214","DOIUrl":"https://doi.org/10.1097/poc.0000000000000214","url":null,"abstract":"<p><strong>Background: </strong>Studies of current opinion of our community members for the characteristics, mode, and location of use, use cases, and overall enthusiasm for point-of-care testing (POCT) diagnosis and management tools are needed.</p><p><strong>Study design and methods: </strong>Qualitative research methods were used to develop, refine, and evaluate hardcopy and electronic versions of a 45-item English language survey. The accuracy of the instrument was measured by recorded structured interview, and its precision was measured by comparison to its administration to a group of uncompensated volunteers.</p><p><strong>Main findings and results: </strong>Comparison of survey and structured interview data demonstrated high levels of accuracy. Highly concordant with significant levels of correlation and of direct association indicated favorable precision. Ninety-three percent of respondents believed that POCT could improve their care, and 56% identified having a POCT in their home as a top priority. Accuracy, insurance coverage, immediacy of results, and ease of use were identified as the most important characteristics of a POCT.</p><p><strong>Conclusions: </strong>Community members strongly support the development of accurate, in-home devices that produce immediate results that can be used to diagnose, manage, and encourage their adherence to treatments for their medical conditions.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"19 4","pages":"112-115"},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547737/pdf/nihms-1702123.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39563962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Overcoming Challenges with the Adoption of Point-of-Care Testing: From Technology Push and Clinical Needs to Value Propositions. 克服采用护理点测试的挑战:从技术推动和临床需求到价值主张。
Point of Care Pub Date : 2020-09-01 DOI: 10.1097/POC.0000000000000209
Brenda J Korte, Anne Rompalo, Yukari C Manabe, Charlotte A Gaydos
{"title":"Overcoming Challenges with the Adoption of Point-of-Care Testing: From Technology Push and Clinical Needs to Value Propositions.","authors":"Brenda J Korte,&nbsp;Anne Rompalo,&nbsp;Yukari C Manabe,&nbsp;Charlotte A Gaydos","doi":"10.1097/POC.0000000000000209","DOIUrl":"https://doi.org/10.1097/POC.0000000000000209","url":null,"abstract":"<p><p>Major technical challenges often prevent developers from producing new point-of-care technologies that deliver the required clinical performance in the intended settings of use. But even when devices meet clinical requirements, they can fail to be adopted and successfully implemented. Adoption barriers occur when decision makers do not understand the \"value proposition\" of new technologies. Current discussions of value in the context of point-of-care testing focus predominantly on the intended use and performance of the device from the manufacturer's point-of-view. However, the perspective of potential adopters in determining whether new devices provide value is also important, as is the opinion of all stakeholders who will be impacted. Incorporating value concepts into decisions made across the full development-to-adoption continuum can increase the likelihood that point-of-care testing will have the desired impact on health care delivery and patient outcomes. This article discusses how various approaches to technology development impact adoption and compares the characteristics of these approaches to emerging value concepts. It also provides an overview of value initiatives and tools that are being developed to support the evaluation of value propositions. These are presented for a range of technology adoption decision contexts, with particular applicability to point-of-care testing. Expanding the focus of research to address gaps in both the creation and evaluation of value propositions is imperative in order for value concepts to positively influence the adoption of point-of-care testing.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"19 3","pages":"77-83"},"PeriodicalIF":0.0,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/POC.0000000000000209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38752457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Toward Improving Accessibility of Point-of-Care Diagnostic Services for Maternal and Child Health in Low- and Middle-Income Countries. 改善低收入和中等收入国家妇幼保健就近诊断服务的可及性。
Point of Care Pub Date : 2019-03-01 Epub Date: 2019-03-05 DOI: 10.1097/POC.0000000000000180
Juliet Katoba, Desmond Kuupiel, Tivani P Mashamba-Thompson
{"title":"Toward Improving Accessibility of Point-of-Care Diagnostic Services for Maternal and Child Health in Low- and Middle-Income Countries.","authors":"Juliet Katoba,&nbsp;Desmond Kuupiel,&nbsp;Tivani P Mashamba-Thompson","doi":"10.1097/POC.0000000000000180","DOIUrl":"https://doi.org/10.1097/POC.0000000000000180","url":null,"abstract":"<p><p>Point-of-care (POC) testing can improve health care provision in settings with limited access to health care services. Access to POC diagnostic services has shown potential to alleviate some diagnostic challenges and delays associated with laboratory-based methods in low- and middle-income countries. Improving accessibility to POC testing (POCT) services during antenatal and perinatal care is among the global health priorities to improve maternal and child health. This review provides insights on the availability of POC testing designed for diagnosing HIV, syphilis, and malaria in pregnancy to improve maternal and child health. In addition, factors such as accessibility of POC testing, training of health work force, and the efficiency of POC testing services delivery in low- and middle-income countries are discussed. A framework to help increase access to POC diagnostic services and improve maternal and child health outcomes in low- and middle-income countries is proposed.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"18 1","pages":"17-25"},"PeriodicalIF":0.0,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/POC.0000000000000180","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37230606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Point-of-Care Diagnosis of Acute Myocardial Infarction in Central Vietnam: International Exchange, Needs Assessment, and Spatial Care Paths. 越南中部急性心肌梗死的护理点诊断:国际交流、需求评估和空间护理路径。
Point of Care Pub Date : 2018-09-01 Epub Date: 2018-08-27 DOI: 10.1097/POC.0000000000000167
Gerald J Kost, Amanullah Zadran, Thuan T B Duong, Tung T Pham, An V D Ho, Nhan V Nguyen, Irene J Ventura, Layma Zadran, Mykhaylo V Sayenko, Kelly Nguyen
{"title":"Point-of-Care Diagnosis of Acute Myocardial Infarction in Central Vietnam: International Exchange, Needs Assessment, and Spatial Care Paths.","authors":"Gerald J Kost, Amanullah Zadran, Thuan T B Duong, Tung T Pham, An V D Ho, Nhan V Nguyen, Irene J Ventura, Layma Zadran, Mykhaylo V Sayenko, Kelly Nguyen","doi":"10.1097/POC.0000000000000167","DOIUrl":"10.1097/POC.0000000000000167","url":null,"abstract":"<p><strong>Objectives: </strong>Objectives were to (<i>a</i>) advance point-of-care (POC) education, international exchange, and culture; (<i>b</i>) report needs assessment survey results from Thua Thien Hue Province, Central Vietnam; (<i>c</i>) determine diagnostic capabilities in regional health care districts of the small-world network of Hue University Medical Center; and (<i>d</i>) recommend Spatial Care Paths that accelerate the care of acute myocardial infarction (AMI) patients.</p><p><strong>Methods: </strong>We organized progressively focused, intensive, and interactive lectures, workshops, and investigative teamwork over a 2-year period. We surveyed hospital staff in person to determine the status of diagnostic testing at 15 hospitals in 7 districts. Questions focused on cardiac rapid response, prediabetes/diabetes, infectious diseases, and other serious challenges, including epidemic preparedness.</p><p><strong>Results: </strong>Educational exchange revealed a nationwide shortage of POC coordinators. Throughout the province, ambulances transfer patients primarily between hospitals, rarely picking up from homes. No helicopter rescue was available. Ambulance travel times from distant sites to referral hospitals were excessive, longer in costal and mountainous areas. Most hospitals (92.3%) used electrocardiogram and creatine phosphokinase-MB isoenzyme to diagnose AMI. Cardiac troponin I/T testing was performed only at large referral hospitals.</p><p><strong>Conclusions: </strong>Central Vietnam must improve rapid diagnosis and treatment of AMI patients. Early upstream POC cardiac troponin testing on Spatial Care Paths will expedite transfers directly to hospitals capable of intervening, improving outcomes following coronary occlusion. Point-of-care coordinator certification and financial support will enhance standards of care cost-effectively. Training young physicians pivots on high-value evidence-based learning when POC cardiac troponin T/cardiac troponin I biomarkers are in place for rapid decision making, especially in emergency rooms.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"17 3","pages":"73-92"},"PeriodicalIF":0.0,"publicationDate":"2018-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8a/2e/poc-17-73.PMC6135481.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36515708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare worker feedback on a prototype smartphone-based point-of-care test platform for use in episodic care. 卫生保健工作者对用于偶发性护理的基于智能手机的原型护理点测试平台的反馈。
Point of Care Pub Date : 2018-06-01 DOI: 10.1097/POC.0000000000000160
Dong Jin Shin, Mitra Lewis, Yu-Hsiang Hsieh, Noha Atef Rahmoun, Charlotte A Gaydos, Tza-Huei Wang, Richard Rothman
{"title":"Healthcare worker feedback on a prototype smartphone-based point-of-care test platform for use in episodic care.","authors":"Dong Jin Shin,&nbsp;Mitra Lewis,&nbsp;Yu-Hsiang Hsieh,&nbsp;Noha Atef Rahmoun,&nbsp;Charlotte A Gaydos,&nbsp;Tza-Huei Wang,&nbsp;Richard Rothman","doi":"10.1097/POC.0000000000000160","DOIUrl":"https://doi.org/10.1097/POC.0000000000000160","url":null,"abstract":"<p><p>With a growing list of new platforms, end-user acceptability is an evolving topic in point-of-care (POC) test development. While technical reports of new experimental POC tests are common, it is rare to find reports which evaluate the end-user acceptability of such innovations. This work illustrates an example of bridging that gap by evaluating the end-user acceptability of an experimental POC test platform with novel technical features. A prototype smartphone-based STI tests was evaluated by ED technicians, followed by a survey of acceptability factors. Our findings suggest that the end-user acceptability of some design features implemented in the prototype.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"17 2","pages":"63-65"},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/POC.0000000000000160","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36515707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Measures and Metrics for Feasibility of Proof-of-Concept Studies With Human Immunodeficiency Virus Rapid Point-of-Care Technologies: The Evidence and the Framework. 人类免疫缺陷病毒快速护理点技术概念验证研究可行性的措施和指标:证据和框架。
Point of Care Pub Date : 2017-12-01 Epub Date: 2017-11-14 DOI: 10.1097/POC.0000000000000147
Nitika Pant Pai, Tiago Chiavegatti, Rohit Vijh, Nicolaos Karatzas, Jana Daher, Megan Smallwood, Tom Wong, Nora Engel
{"title":"Measures and Metrics for Feasibility of Proof-of-Concept Studies With Human Immunodeficiency Virus Rapid Point-of-Care Technologies: The Evidence and the Framework.","authors":"Nitika Pant Pai,&nbsp;Tiago Chiavegatti,&nbsp;Rohit Vijh,&nbsp;Nicolaos Karatzas,&nbsp;Jana Daher,&nbsp;Megan Smallwood,&nbsp;Tom Wong,&nbsp;Nora Engel","doi":"10.1097/POC.0000000000000147","DOIUrl":"https://doi.org/10.1097/POC.0000000000000147","url":null,"abstract":"<p><strong>Objective: </strong>Pilot (feasibility) studies form a vast majority of diagnostic studies with point-of-care technologies but often lack use of clear measures/metrics and a consistent framework for reporting and evaluation. To fill this gap, we systematically reviewed data to (<i>a</i>) catalog feasibility measures/metrics and (<i>b</i>) propose a framework.</p><p><strong>Methods: </strong>For the period January 2000 to March 2014, 2 reviewers searched 4 databases (MEDLINE, EMBASE, CINAHL, Scopus), retrieved 1441 citations, and abstracted data from 81 studies. We observed 2 major categories of measures, that is, implementation centered and patient centered, and 4 subcategories of measures, that is, feasibility, acceptability, preference, and patient experience. We defined and delineated metrics and measures for a feasibility framework. We documented impact measures for a comparison.</p><p><strong>Findings: </strong>We observed heterogeneity in reporting of metrics as well as misclassification and misuse of metrics within measures. Although we observed poorly defined measures and metrics for feasibility, preference, and patient experience, in contrast, acceptability measure was the best defined. For example, within feasibility, metrics such as consent, completion, new infection, linkage rates, and turnaround times were misclassified and reported. Similarly, patient experience was variously reported as test convenience, comfort, pain, and/or satisfaction. In contrast, within impact measures, all the metrics were well documented, thus serving as a good baseline comparator. With our framework, we classified, delineated, and defined quantitative measures and metrics for feasibility.</p><p><strong>Conclusions: </strong>Our framework, with its defined measures/metrics, could reduce misclassification and improve the overall quality of reporting for monitoring and evaluation of rapid point-of-care technology strategies and their context-driven optimization.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"16 4","pages":"141-150"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1097/POC.0000000000000147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35736496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Which Point-of-Care Tests Would Be Most Beneficial to Add to Clinical Practice?: Findings From a Survey of 3 Family Medicine Clinics in the United States. 在临床实践中增加哪些护理点检测最有益?美国 3 家全科诊所的调查结果。
Point of Care Pub Date : 2017-12-01 Epub Date: 2017-11-14 DOI: 10.1097/POC.0000000000000151
Victoria Hardy, William Alto, Gina A Keppel, Laura-Mae Baldwin, Matthew Thompson
{"title":"Which Point-of-Care Tests Would Be Most Beneficial to Add to Clinical Practice?: Findings From a Survey of 3 Family Medicine Clinics in the United States.","authors":"Victoria Hardy, William Alto, Gina A Keppel, Laura-Mae Baldwin, Matthew Thompson","doi":"10.1097/POC.0000000000000151","DOIUrl":"10.1097/POC.0000000000000151","url":null,"abstract":"<p><strong>Background: </strong>Point-of-care tests (POCTs) are increasingly used in family medicine to facilitate screening, diagnosis, monitoring, treatment, and referral decisions for a variety of conditions. Point-of-care tests that clinicians believe might be beneficial to add to clinical practice and the conditions for which they would be most useful in family medicine remain poorly understood in the United States.</p><p><strong>Methods: </strong>Forty-two clinicians at 3 family medicine residency clinics completed a brief survey asking which POCTs they believed would be beneficial to add to their clinical practice and the conditions POCTs would be most useful for. We calculated frequencies of reported POCTs and conditions using descriptive statistics.</p><p><strong>Results: </strong>Clinicians identified 34 POCTs that would be beneficial to add to family medicine, of which hemoglobin A<sub>1c</sub>, chemistry panels, and human immunodeficiency virus and gonococcal and/or chlamydia were most frequently reported and anticipated would be used weekly. Clinicians reported 30 conditions for which they considered POCTs would be useful. Diabetes mellitus, sexually transmitted infections, and respiratory tract infections were the most often reported and were identified as benefiting diagnosis, monitoring, and treatment decisions.</p><p><strong>Conclusions: </strong>Clinicians identified a number of POCTs they viewed as being beneficial to add to their routine clinical practice, mostly to inform diagnosis and treatment planning. Some POCTs identified are available in the United States; thus, understanding barriers to implementation of these POCTs in primary care settings is necessary to optimize adoption.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"16 4","pages":"168-172"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4d/ac/poc-16-168.PMC5737459.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35736497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Point-of-Care Diagnostics on Maternal Outcomes in Human Immunodeficiency Virus-Infected Women: Systematic Review and Meta-analysis. 即时诊断对人类免疫缺陷病毒感染妇女产妇结局的影响:系统回顾和荟萃分析
Point of Care Pub Date : 2017-06-01
Tivani P Mashamba-Thompson, Rebecca L Morgan, Benn Sartorius, Brittany Dennis, Paul K Drain, Lehana Thabane
{"title":"Effect of Point-of-Care Diagnostics on Maternal Outcomes in Human Immunodeficiency Virus-Infected Women: Systematic Review and Meta-analysis.","authors":"Tivani P Mashamba-Thompson, Rebecca L Morgan, Benn Sartorius, Brittany Dennis, Paul K Drain, Lehana Thabane","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>The World Health Organization advocates for increased accessibility of HIV-related point-of-care (POC) diagnostics in settings that lack laboratory infrastructure. The aim of this study is to assess the impact of POC diagnostics on maternal health outcomes in HIV-infected women.</p><p><strong>Methods: </strong>A systematic literature review used multiple data sources as follows: Cochrane Infectious Disease Group Specialized Register; Cochrane Central Register of Control Trials, published in The Cochrane Library; PubMed; EBSCOhost and LILACS from January 2000 to October 2015. References of included studies were hand searched. Randomized controlled trials (RCTs) and observational studies examining health outcomes of HIV-infected women were eligible for inclusion in this review. The Cochrane Risk of Bias tool was used for bias assessment of the included studies. PRISMA guidelines were used for reporting.</p><p><strong>Results: </strong>Of the 695 studies identified, six retrievable studies (five cross-sectional studies and one case control study) met the inclusion criteria and were included in this study. These studies examined a total of 167 HIV-infected women in different study settings. No studies reported evidence of CD4 count, viral load and TB, and the syphilis POC test impact on HIV-infected women was not found by this study. Included studies reported the impact of various HIV rapid tests across the following five maternal outcomes: timely receipt of results with pooled effect size (ES) = 1.00 (95% confidence interval [CI]: (0.98; 1.02); enabling partner testing, ES = 0.95 (0.85; 1.04); prevention of mother-to-child transmission of HIV, ES = 0.86 (0.79; 0.93); linkage to antiretroviral treatment (ART), ES = 0.76 (0.69; 0.84); and linkage to HIV care, ES = 0.50 (0.18; 0.82). No studies reported evidence of the impact of POC testing on maternal mortality or maternal and child morbidity of HIV-infected women.</p><p><strong>Conclusions: </strong>The review provides an international overview of the impact of HIV POC diagnostics on maternal outcomes in HIV-infected women, showing the evidence that the HIV POC test is significantly associated with decreased mother-to-child transmission of HIV and increased linkage to ART and HIV care for HIV-infected women. It also revealed a gap in the literature aimed at assessing the impact of POC diagnostics on maternal morbidity and mortality in HIV-infected women.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"16 2","pages":"67-77"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5726275/pdf/nihms863547.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35658062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Type 1 Diabetes - A Clinical Perspective. 1 型糖尿病--临床视角。
Point of Care Pub Date : 2017-03-01 DOI: 10.1097/POC.0000000000000125
Lindy Kahanovitz, Patrick M Sluss, Steven J Russell
{"title":"Type 1 Diabetes - A Clinical Perspective.","authors":"Lindy Kahanovitz, Patrick M Sluss, Steven J Russell","doi":"10.1097/POC.0000000000000125","DOIUrl":"10.1097/POC.0000000000000125","url":null,"abstract":"<p><p>Type 1 diabetes is a disease in which autoimmune destruction of pancreatic β-cells leads to insulin deficiency. Controlling blood glucose with an acceptable range is a major goal of therapy. Measurements of hemoglobin A1c and blood glucose levels are used for both the diagnosis and the long-term management of the disease. This chapter briefly describes the pathophysiology, diagnosis, and management of type 1 diabetes.</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"16 1","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5606981/pdf/nihms842436.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35541757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction of Point-of-Care INR Results in Warfarin Patients. 纠正华法林患者的医护点 INR 结果。
Point of Care Pub Date : 2016-03-01 DOI: 10.1097/POC.0000000000000077
Christopher Richter, James Taylor, Jonathan Shuster
{"title":"Correction of Point-of-Care INR Results in Warfarin Patients.","authors":"Christopher Richter, James Taylor, Jonathan Shuster","doi":"10.1097/POC.0000000000000077","DOIUrl":"10.1097/POC.0000000000000077","url":null,"abstract":"<p><strong>Background: </strong>The measurement of international normalization ratio (INR) may be done by venous blood draw and use of a standard lab, or by fingerstick, using a point of care (POC) device such as the CoaguChek XS<sup>®</sup> (Roche Diagnostics), and the CoaguChek XS<sup>®</sup> has been validated to meet the International Organization for Standardization (ISO) performance requirements.</p><p><strong>Overview: </strong>The goal of this study was to determine a correction factor for Coaguchek XS INR levels to a predicted venipuncture (VP) INR level.</p><p><strong>Methods: </strong>At the end of an anticoagulation clinic visit when a patient had an INR greater than or equal to 4, two INR results existed, that from the Coaguchek XS<sup>®</sup> meter and a venipuncture INR from the lab. The data were then discreetly recorded as a quality control for our clinic. The data were analyzed for possible significant trends between the two types of INR results.</p><p><strong>Results: </strong>The equation that was determined to be the best fit to the data was 0.621 × POC + 0.639 = estimated VP. The overall root mean square error (MSE) for the calculated correction was a 0.44 INR. The root mean square errors were 0.41 and 0.58 for the 4 to 5.9 and 6 to 7.9 POC INR groups, respectively.</p><p><strong>Conclusion: </strong>The calculation that was derived in this study is not a surrogate for venipuncture INR in this clinic. However, the estimation of the INR may be useful clinically in guiding decision making in the future. (INR, Point of Care, Anticoagulation, Hematology).</p>","PeriodicalId":44085,"journal":{"name":"Point of Care","volume":"15 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834836/pdf/nihms724652.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34482788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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