{"title":"Modern ideas about metaepiphyseal osteomyelitis. Review","authors":"Vadim V. Grishaev, A. Shamsiev","doi":"10.17816/psaic1495","DOIUrl":"https://doi.org/10.17816/psaic1495","url":null,"abstract":"This paper presents a review of domestic and foreign literature on the issues of diagnosis and treatment of young children with metaepiphyseal osteomyelitis, the changes in the immune system and cytokine levels, and the targeted correction of the disorders that have arisen. This work aims to highlight modern approaches to the diagnosis and treatment of metaepiphyseal osteomyelitis in young children with emphasis on the changes in the immune status of the patient. \u0000Literary search was performed in the databases in Russian eLibrary.ru, English Medline, Web of Science, and PubMed using the following keywords: metaepiphyseal osteomyelitis, infants, immune system, cytokines, interleukins, and roncoleukin. A total of 405 papers were found, of which 66 were fully consistent with the purpose of our study and thus selected for the analysis. \u0000Results showed that the search for effective methods for the early diagnosis of the osteomyelitic process in young children continues to be relevant; no study has provided a complete picture of the severity of the pathological process. Although numerous studies have been performed, no consensus has been achieved in assessing the significance of changes in the parameters of the immune system and its cytokine link during the development of metaepiphyseal osteomyelitis. The data indicated a positive effect of the use of recombinant interleukin-2 in the complex treatment of a number of diseases, especially in young children with various pathological conditions. Metaepiphyseal osteomyelitis in young children is an urgent problem in pediatric surgery largely due to the increase in the number of children with reduced immuno-biological reactivity, which requires the use of effective immunocorrection agents as part of the complex etiotropic and pathogenetic treatment. This approach applies to such powerful means of immunocorrection as recombinant cytokine preparations.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124946316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In memory of Anatoly P. Zilber (13.02.1931 – 25.04.2023)","authors":"A. U. Lekmanov","doi":"10.17816/psaic1520","DOIUrl":"https://doi.org/10.17816/psaic1520","url":null,"abstract":"Information about the life path of the founder of domestic anesthesiology and resuscitation, Professor Anatoly P. Zilber.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"77 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133028061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Sukhotskaya, I. Kagantsov, V. Bairov, M. G. Vitovshchik, I. Nikitina, D. Ryzhkova, L. Mitrofanova, L. R. Sarakaeva
{"title":"Successful laparoscopic resection of a rare focal form of congenital hyperinsulinism: Case report and literature review","authors":"A. Sukhotskaya, I. Kagantsov, V. Bairov, M. G. Vitovshchik, I. Nikitina, D. Ryzhkova, L. Mitrofanova, L. R. Sarakaeva","doi":"10.17816/psaic1501","DOIUrl":"https://doi.org/10.17816/psaic1501","url":null,"abstract":"Congenital hyperinsulinism is a severe disease that causes irreversible damage to the cerebral cortex. This article presents a clinical observation of successful surgical treatment for a child with an extremely rare form of hyperinsulinism accompanied by two foci in the opposite ends of the pancreas. The child was in extremely critical condition from birth due to recurrent hypoglycemia and was diagnosed with hyperinsulinism at the age of two weeks. Specific therapy with diazoxide and octreotide was initiated but proven to be ineffective (parenteral glucose administration was still needed, and octreotide only provided partial results). When the child was one month old, positron emission tomography-computed tomography with 18F-DOPA was performed and revealed the focal hyperfixation of the radiopharmaceutical in the tail and head of the pancreas. This finding indicated the presence of two pathological foci or a focus in the tail and the physiological accumulation of the radiopharmaceutical in the head. At the age of one month and 20 days, the child underwent laparoscopic revision of the pancreas to visualize a focus in the tail that was confirmed by express biopsy. The resection of the tail (15%) was performed with confirmation of clear resection margins. During further revision, a focus was detected in the head. Resection was again performed with histological confirmation of complete resection. On the 12th day after the operation, the child was discharged without therapy with clinical recovery. The child is currently being monitored (for over six months), growing and developing according to age. A fasting test was performed, and the recurrence of hyperinsulinism was ruled out. This article presents a detailed description of the clinical and radiological examination results, the patients history, the surgical techniques, and the intervention results. As part of the discussion, a literature review on the behavior of laparoscopic resections of the pancreas in children with congenital hyperinsulinism was carried out.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114637344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kozlov, S. Poloyan, A. A. Marchuk, Alexander P. Rozhanskii, A. A. Byrgazov, S. A. Muravev, K. Kovalkov, V. Kapuller, A. Narkevich
{"title":"Use of ICG navigation in organ-preserving resections of ovarian teratomas in children","authors":"Y. Kozlov, S. Poloyan, A. A. Marchuk, Alexander P. Rozhanskii, A. A. Byrgazov, S. A. Muravev, K. Kovalkov, V. Kapuller, A. Narkevich","doi":"10.17816/psaic1503","DOIUrl":"https://doi.org/10.17816/psaic1503","url":null,"abstract":"This study presents the first experience of indocyanine green imaging for ovarian tumors in girls to show how the development of new imaging technologies can change the treatment of this pathology. \u0000A retrospective analysis was conducted on the case histories of a 12-year-old girl and a 15-year-old girl with ovarian teratomas who were admitted with complaints of discomfort and pain in the lower abdomen. Ultrasound and computed tomography of the abdominal cavity revealed tumors with sizes of 40 42 38 and 60 54 38 mm in the right ovary for one girl and in the left ovary for the other girl. No increase in the concentration of tumor markers (alpha-fetoprotein, -chorionic gonadotropin, and Cancer Antigen 125) was recorded. Operations for the diagnosis of ovarian teratoma were performed laparoscopically using fluoroscopic control. The use of indocyanine green imaging was effective in determining the boundaries of the tumor and healthy ovarian tissues, making it possible to perform organ-sparing surgery. During the surgical intervention, no complications were observed in the form of bleeding from the ovarian parenchyma or damage to neighboring organs. Histological diagnosis established that the neoplasms belong to mature teratomas. The length of hospital stay was three days. Ultrasound examination performed six months after surgery showed no signs of disease recurrence. One of the patients exhibited regeneration of ovarian tissues comparable with the size of the contralateral ovary. In another girl, the affected ovary was about half the size. \u0000Thus, organ-preserving surgical treatment for ovarian teratomas in children is the method of choice. A fundamental innovation is the use of indocyanine green fluorescence technology to determine the boundaries of the spread of the tumor in order to resect it within healthy tissues.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129042619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In memory of Grachik T. Tumanyan (15.01.1946 – 12.05.2023)","authors":"Y. Sokolov","doi":"10.17816/psaic1522","DOIUrl":"https://doi.org/10.17816/psaic1522","url":null,"abstract":"The paper discusses the professional life of the late pediatric surgeon, Professor Grachik T. Tumanyan.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131624191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdullo S. Safarov, Aslamkhon M. Sharipov, A. T. Korokhonov, Bokhodur A. Safarov
{"title":"Debatable problems of classification of modern hematogenous osteomyelitis in children","authors":"Abdullo S. Safarov, Aslamkhon M. Sharipov, A. T. Korokhonov, Bokhodur A. Safarov","doi":"10.17816/psaic1290","DOIUrl":"https://doi.org/10.17816/psaic1290","url":null,"abstract":"Basing on their own experience in the diagnosis and treatment of children with hematogenous osteomyelitis and their study of domestic and foreign sources, the authors came to the conclusion that in all classifications available, consensus is lacking on the origin, course, form, stage, phase, outcome, and consequences of hematogenous osteomyelitis in children. This realization prompted us to revise the classification of hematogenous osteomyelitis in children. \u0000The proposed new classification of hematogenous osteomyelitis in children was developed by amending the existing ones. It consists of 10 headings: etiology, origin, course, form, stages, localization, morphological form, complications, outcome, and consequences. Along the course, hematogenous osteomyelitis was divided into acute, subacute, and atypical forms. In addition to the allocation of subacute hematogenous osteomyelitis, a separate section gives a brief description of the features of its course and clinical manifestations. Hematogenous osteomyelitis of bones forming joints and hematogenous osteomyelitis of mixed bones (spine) were added to the Localization section, and apophyseal localization was added to osteomyelitis of tubular bones. In the Outcome section in the Recovery section, four subsections were highlighted. \u0000We submit this classification for discussion and await opinions and suggestions from pediatric surgeons on improving the classification of hematogenous osteomyelitis in children.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132934307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"To Anniversary of Olga G. Mokrushina","authors":"Vasily S. Shumikhin","doi":"10.17816/psaic1524","DOIUrl":"https://doi.org/10.17816/psaic1524","url":null,"abstract":"The paper describes the professional activities and merits of the pediatric surgeon Olga G. Mokrushina in celebration of her anniversary.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130851927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In memory of Evgeny Ya. Gatkin (02.01.1954 – 27.12.2022)","authors":"N. B. Guseva","doi":"10.17816/psaic1521","DOIUrl":"https://doi.org/10.17816/psaic1521","url":null,"abstract":"Information about the untimely deceased pediatric surgeon, doctor of medical sciences, Evgeny Ya. Gatkin.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128655230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Satvaldieva, D. B. Tuychiev, D. Ashurov, Ikbol Kh. Sayramov
{"title":"Postoperative analgosedation with dexmedetomidine in combination with paracetamol in pediatric cardiac surgery","authors":"E. Satvaldieva, D. B. Tuychiev, D. Ashurov, Ikbol Kh. Sayramov","doi":"10.17816/psaic1514","DOIUrl":"https://doi.org/10.17816/psaic1514","url":null,"abstract":"BACKGROUND: Although the principles of postoperative multimodal analgesia have been discussed in several articles, this issue remains insufficiently studied in pediatric cardiac surgery. \u0000AIM: To increase the effectiveness of postoperative analgosedation in children after heart surgery by combining intravenous dexmedetomidine and paracetamol. \u0000MATERIALS AND METHODS: Prospective, nonrandomized, controlled study (n = 65, 24 yr). Elective heart surgeries were performed in children with congenital heart defects, such as ventricular and/or interatrial septal defect and tetralogy of Fallot, under cardiopulmonary bypass and general anesthesia. Patients were divided into two groups according to the type of postoperative analgesia: group 1, main (n = 35): 30 min after surgery, infusion of dexmedetomidine with a loading dose of 1.0 g/kg/h or 10 min, then infusion of 0.8 g/kg/h during the day against the background of planned analgesia with paracetamol (15 mg/kg, intravenously) 2 h after surgery and then every 8 h during the day; group 2, comparisons (n = 30), 0.3 mg/kg morphine, intramuscularly. The effectiveness of postoperative analgosedation in children was analyzed using the Richmond scale and FLACC + hemodynamics, acid-base balance, blood gases, cortisol, glucose, and blood lactate. \u0000RESULTS: Sufficient stabilization of the main hemodynamics and respiratory indicators confirmed the adequacy of postoperative analgosedation in group 1 patients. There was a 14% drop in heart rate, specific peripheral resistance, and mean arterial pressure. There was no respiratory depression observed, and the decrease in blood pressure and heart rate was hemodynamically modest. Postoperative stability of blood lactate, glucose, and cortisol levels demonstrated the absence of major metabolic diseases and emotional and physical stress in the main group of children. The transfer of 74.3% of the first group's patients to the specialized department 42.3 5.5 h after the procedure decreased costs and strain on the intensive care unit staff. \u0000CONCLUSIONS: Dexmedetomidine combined with paracetamol provides an adequate level of sedation, suppresses extubation irritations, prevents psychomotor agitation, and provides sufficient analgesia.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125138085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"To the 75th Anniversary of Vladimir G. Bairov","authors":"I. Kagantsov, A. Sukhotskaya","doi":"10.17816/psaic1518","DOIUrl":"https://doi.org/10.17816/psaic1518","url":null,"abstract":"The paper describes the professional activities and merits of the pediatric surgeon Vladimir G. Bairov, in celebration of his anniversary.","PeriodicalId":437552,"journal":{"name":"Russian Journal of Pediatric Surgery, Anesthesia and Intensive Care","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125355101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}