Reanimation最新文献_第7页

Sédation légère chez les patients en insuffisance respiratoire aiguë 急性呼吸功能不全患者的轻度镇静

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/S13546-015-1147-2

G. Ledoux, N. Terzi, E. Jaillette, R. Lawson, N. Masli, R. Favory

引用次数: 0

Sécurité autour du patient 病人周围的安全

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/s13546-015-1135-6

Srlf 2015

引用次数: 0

Session e-poster 会话e-poster

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/s13546-015-1144-5

Srlf 2015

引用次数: 0

Rôle IDE dans la mise en place et la surveillance de l’ECCO2R fdi在建立和监测ecco2r中的作用

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/S13546-015-1153-4

M. Meyer, M. Kernmarc, F. Manciet, I. Caminade, J. Diehl

引用次数: 0

[Is control fever mandatory in severe infections?] [严重感染是否必须控制发烧？］

Reanimation Pub Date : 2016-01-01 Epub Date: 2016-03-11 DOI: 10.1007/s13546-015-1168-x

P Seguin, Y Launey, N Nesseler, Y Malledant

{"title":"[Is control fever mandatory in severe infections?]","authors":"P Seguin, Y Launey, N Nesseler, Y Malledant","doi":"10.1007/s13546-015-1168-x","DOIUrl":"10.1007/s13546-015-1168-x","url":null,"abstract":"Temperature control during severe sepsis is currently used in intensive care and involves 66% and 70% of severe sepsis and septic shock, respectively. Nevertheless, the conclusive evidence of the benefit of such a strategy is still lacking.We might wonder, with regards to experimental works and recent noninterventional studies, about the risk of a control strategy on an ongoing infectious process, the patient's outcome, and the safety of the means implemented to obtain temperature control. On the other hand, it is also demonstrated that fever increases oxygen consumption, which may lead in some clinical situations to tissular ischemia and that fever may be associated with a deleterious focal inflammatory process. Methods to control the temperature include external and/or internal cooling and/or antipyretic medications such as paracetamol and nonsteroidal antiinflammatory drugs. In septic patients, external cooling and paracetamol are the mains means used to control temperature. Despite the uncertainties about the benefit to control or not the temperature, it could be stated that extreme temperature (hypo- or hyperthermia) should be avoided and that the benefit/risk of temperature control must be individually weighted.","PeriodicalId":43743,"journal":{"name":"Reanimation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7117820/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37832416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Modulation of transcriptomic signature of the infected host: a new therapeutic strategy for the management of severe viral infections? Example of the flu]. 受感染宿主转录组特征的调节:一种治疗严重病毒感染的新策略?流感的例子]。

Reanimation Pub Date : 2016-01-01 Epub Date: 2016-04-07 DOI: 10.1007/s13546-016-1188-1

J Poissy, O Terrier, B Lina, J Textoris, M Rosa-Calatrava

{"title":"[Modulation of transcriptomic signature of the infected host: a new therapeutic strategy for the management of severe viral infections? Example of the flu].","authors":"J Poissy, O Terrier, B Lina, J Textoris, M Rosa-Calatrava","doi":"10.1007/s13546-016-1188-1","DOIUrl":"https://doi.org/10.1007/s13546-016-1188-1","url":null,"abstract":"During the last decades, emergence and reemergence of viruses were responsible for epidemic and pandemic infectious diseases, with variable degrees of severity. Current preventive strategies are not sufficient at all, and available therapeutic drugs are very limited. Indeed, genetic variations of viruses can impair the efficacy of antiviral compounds by the apparition of resistance. Moreover, current delay needed for de novo development of drugs does not allow a rapid response in case of important epidemic or pandemic events. In this context, new therapeutic approaches are necessary. An innovative concept is to repurpose already marketed compounds that can reverse the host cellular transcriptomic response to the infection. By targeting the host, these molecules exhibit a broad-spectrum activity and are potentially effective even against new emergent strains. This strategy implements the characterization of specific host gene expression profiles, the in silico screening of drugs, and their validation in in vitro and in vivo models, until their evaluation in clinical trials. Here, we will present this approach, with the example of the flu.","PeriodicalId":43743,"journal":{"name":"Reanimation","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s13546-016-1188-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37832417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Les pneumonies d’inhalation 吸入性肺炎

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/S13546-015-1155-2

D. Chatellier, S. Cabasson, R. Robert

引用次数: 0

Sommeil en réanimation et impact de la ventilation mécanique 复苏睡眠和机械通气的影响

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/S13546-015-1152-5

Serge Carreira, S. Lavault, A. Demoule

引用次数: 1

Recherche infirmière 研究护士

Reanimation Pub Date : 2016-01-01 DOI: 10.1007/s13546-015-1138-3

Srlf 2015