Byulleten Sibirskoy Meditsiny最新文献

{"title":"Нарушение водно-электролитного обмена у пациентов с камнями мочеточников после контактной литотрипсии","authors":"Валентин Николаевич Павлов, А. М. Пушкарев, Алексеев Александр Владимирович, И. Г. Ракипов, Д. Р. Мусин, Адель Альбертович Измайлов","doi":"10.20538/1682-0363-2012-2-40-43","DOIUrl":"https://doi.org/10.20538/1682-0363-2012-2-40-43","url":null,"abstract":"Urolithiasis is one of the most common urologic diseases, and 50% of patients with urolithiasis have ureteral stones. As with ureterolitiaze and in contact lithotripsy has been established development of glomerular and tubular dysfunction, which causes up to 9% of complications. Investigation of the parameters water-electrolyte metabolism carried out 52 patients with urolithiasis before and after contact ureterolitotripsi. Once installed KLT increase in glomerular filtration rate by 61% of the daily creatinine excretion a 43% urea 21%, sodium 28%, chlorides 55%, the concentration of ACTH 53% of cortisol 11%. In the urine increases the concentration of indicators of the glomerular and tubular dysfunction mikroalbumina 3 times, β2-microglobulin was 4,5 times, Ngala was 58%. The identified changes areapparently caused by intrarenal mechanisms only, because the major hormonal systems that regulate water and electrolyte metabolism, did not significantly change the parameters of its operation.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2016-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67684653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antiinflammatory and antibacteriological properties of extracts from aboveground part of Delphinium elatum L. (ranunculaceae)","authors":"T. N. Povetiyeva, Y. Nesterova, A. V. Krapivin, N. I. Suslov, L. V. Lavrentiyeva, S. S. Kravtsova, Yu. G. Nagornyak","doi":"10.20538/1682-0363-2012-3-58-61","DOIUrl":"https://doi.org/10.20538/1682-0363-2012-3-58-61","url":null,"abstract":"В последнее время во всем мире отмечается повышенный интерес практической медицины к лекарственным препаратам, получаемым из растительного сырья. Среди природных фармакологически активных веществ алкалоиды являются основной группой, из которой современная медицина черпает наибольшее количество высокоэффективных лекарственных средств. Живокость высокая (Delphinium elatum L.) является малоизученным растением. Все его части содержат дитерпеновые алкалоиды, среди которых доминирующим является элатин [6]. В официнальной медицине препараты живокости применяются для лечения заболеваний центральной нервной системы [5]. Народная медицина издавна использовала живокость высокую для лечения заболеваний желудочно-кишечного тракта, в качестве ранозаживляющего, обезболивающего и противовоспалительного средства [2, 4]. Цель исследования — изучение противовоспалительных и антибактериальных свойств извлечений из надземной части живокости высокой.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67684681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to protect oneself against medical errors","authors":"F. F. Tetenev","doi":"10.20538/1682-0363-2012-1-122-127","DOIUrl":"https://doi.org/10.20538/1682-0363-2012-1-122-127","url":null,"abstract":"The paper is devoted to the problem of medical errors in diagnosing. With the Siberian clinical school taken as an example, the theory of formation of clinical experience from the gradual accumulation of experience by the school founders to the active formation of clinical thinking through the use of the theory of diagnosing is presented.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2016-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67684515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ИГРОВОЕ БИОУПРАВЛЕНИЕ ПРИ СИНДРОМЕ ДЕФИЦИТА ВНИМАНИЯ С ГИПЕРАКТИВНОСТЬЮ","authors":"И. А. Столлер, Е. Г. Веревкин, М. В. Сухоленцева","doi":"10.20538/1682-0363-2013-2-166-174","DOIUrl":"https://doi.org/10.20538/1682-0363-2013-2-166-174","url":null,"abstract":"We continue the study of students with attention deficit hyperactivity disorder when using betastimulating game neurofeedback. The dynamics of segmental characteristics of the alpha rhythm and θ/β ratio for different groups of successful training. Evaluate the effectiveness of training in terms of the number of ADHD symptoms (at the beginning and end of the training).","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2016-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67684861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"NEUROFEEDBACK AND EMG TRAINING COMBINING EFFICIENCY STUDY IN 6–9 YEARS OLD ADHD CHILDREN","authors":"Ye. А. Sapina","doi":"10.20538/1682-0363-2013-2-161-165","DOIUrl":"https://doi.org/10.20538/1682-0363-2013-2-161-165","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67684812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ассоциация генов подверженности к алкоголизму, шизофрении и болезни Альцгеймера с психодиагностическими признаками в популяции русских","authors":"Марусин Андрей Викторович, Корнетов Александр Николаевич, Сваровская Мария Геннадьевна, Вагайцева Ксения Валерьевна, Павленюк Екатерина Степановна, Степанов Вадим Анатольевич","doi":"10.20538/1682-0363-2016-5-83-96","DOIUrl":"https://doi.org/10.20538/1682-0363-2016-5-83-96","url":null,"abstract":"The purpose of this paper is to identify genetic factors connected with personal features using the panel of 12 polymorphic markers associated with the risk of developing dementia in patients with Alzheimer’s disease, schizophrenia and alcoholism. Materials and methods. The correlation among quantitative traits of personality, temperament and character determined with Cattell’s (the Sixteen personality factor questionnaire (16PF)), Leonhard-Schmieschek’s, Spielberger-Khanin’s, and Eysenck’s (IQ) tests were analyzed with polymorphic variants of 12 genes involved in the development of severe mental disorders such as alcoholism, schizophrenia and Alzheimer’s disease. DNA samples of 150 students were genotyped using PCR-RPLF method. The data were processed by nonparametric statistical methods. Results. Interallelic nonrandom associations in paired combinations of GABRA2-PICALM, PICALMADCY3, CLU-CBX7 and CLU-ADCY3 polymorphisms were detected. This may indicate the adaptive selection influencing the maintenance of behavioral homeostasis in population. A number of statistically significant associations of genetic variation were found: CLU with perfectionism(Q3) of 16PF and the exaltation of the Leonhard’s tests, PICALM with tension (Q4) of 16PF and the imbalance of Leonhard’s tests, DISC1 with vigilance(L) of 16PF, and exaltation, cyclothymia of Leonhard’s tests, ZNF804A with imbalance by Leonhard’s test, SLC6A4 with reasoning(B) of 16PF test, ADCY3 with self-reliance(Q2) and extraversion(F2) of 16PF test, MIR9-2 emotional stability(C), liveliness(F), social boldness(H), extraversion(F2) of 16PF, and dysthymia, hyperthymia of Leonhard’s tests, with the personal anxiety of Spielberger-Khanin’s test, CBX7 with vigilance(L), warmth(A) of 16PF test, SLC6A3 with IQ. Conclusion. These findings support the idea of overlapping genetic component in common mental and neurological disorders and variability of human cognitive and personality traits.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67686332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"УПРАВЛЕНИЕ ИННОВАЦИОННОЙ ДЕЯТЕЛЬНОСТЬЮ В ЗДРАВООХРАНЕНИИ НА РЕГИОНАЛЬНОМ УРОВНЕ","authors":"Елена Геннадьевна Тоцкая, Михаил Анатольевич Садовой","doi":"10.20538/1682-0363-2014-5-184-194","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-5-184-194","url":null,"abstract":"The paper reviews topical issues of organization and management of innovative activity in the regional health care system. Objective . Development and scientific substantiation of a conceptual model of managing innovation in the regional health care system, introduction of institutional mechanisms for its implementation, and evaluation of their efficacy in using diagnosis and treatment technologies. Objectives of the study included reviewing the organization status and problems hampering the development, identification of prospects, and justification for appropriate changes in innovation in healthcare system and medical science at the regional level. Material and methods . To conduct a comprehensive assessment of the status and meet challenges of innovation promotion, a methodology for social-hygienic research was worked out including bibliographic and analytical methods, situational analysis, sociological and economic methods, expert assessment, methods for quality management system audit in accordance with ISO 19011:2002, IDEFO function modeling (RD IDEF0-2000), and organizational modeling. The study was based on the analysis of foreign and domestic literature, statistics, methods for managerial modeling, as well as management experience (including innovative methodological approaches) gained by Novosibirsk Research Institute of Traumatology and Orthopedics named after Ya.L. Tsivyan which meets the requirements for a platform for research and innovative product reproduction, including research, clinical, organizational, and managerial aspects. Other facilities were considered in conjunction with the leading innovative platform. Results . The paper presents a scientifically based model of innovative medical environment with its elements as subjects, each with a set of functions. Conceptual model for management includes structuring (resource, processes, and quality management; application of international standards) and strategic management mechanisms, provides a systematic approach to management, and ensures efficient operation of medical institutions and public access to innovative medical diagnostic technologies. The advantage of innovative products and technologies using within the doctrine of innovative management is that they provide a comprehensive approach to the diagnosis and treatment of patients. The introducted managing innovation technologies allow to improve organizational performance of healthcare institutions and to achieve significant medical and social effects: high level of diagnosis and treatment, improved access and quality of care what promotes the public health. Conclusion . Formation of regional innovation medical environment with advanced innovation infrastructure, interaction of its elements through an effective system of coordination and control is a prerequisite and basis for more mature and system-level structure – an industry innovative cluster. Active development of innovation in health care based on cooperation amo","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ОСОБЕННОСТИ ОСНОВНЫХ ПОКАЗАТЕЛЕЙ ФИЗИЧЕСКОГО РАЗВИТИЯ ПОДРОСТКОВ В ТОМСКОЙ ОБЛАСТИ","authors":"I. A. Deyev, I. L. Kolomeyets, Ye. M. Kamaltynova, Y. S. Kulikov, A. N. Levko, O. S. Fyodorova, Kristina V. Kulikova, V. I. Yurkova","doi":"10.20538/1682-0363-2015-6-40-47","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-6-40-47","url":null,"abstract":"Objective. To study the physical growth and development of adolescents (aged 13–16 years) living in the Tomsk region.  Material and Methods. This study is a framework (№299 from 18.07.2011) of the Department of Health Care of Tomsk region, we analyzed the results of medical examinations of adolescents (n = 7120, average age 13.98 ± 0.04, 49.87% – boys). Measurements of height and weight, the circumference of the chest and head (data rounded to 0.1 kg and 0.1 cm, respectively) are taken. The body mass index (BMI) is calculated as the ratio of weight (kg) / height2 (m2). Statistical analysis was performed using the software package Statistica for Windows 10.0 and the software StatCalc 6.0. Results. Average height of adolescents is (163.10 ± 0.09) cm. On Average boys are taller than girls ((165.34 ± 0.15) cm and (160.87 ± 0.11) cm, p < 0.001). The body weight is (53.99 ± 0.13) kg (boys – (55.28 ± 0.20) kg, girls – (52.72 ± 0.17) kg, p < 0.001). Boys chest circumference is (79.26 ± 0.30) cm, girls is (79.99 ± 0.13) cm, head circumference are (55.43 ± 0.07) cm and (54.77 ± 0.04) cm, respectively (p < 0.01). The results show difference between Tomsk boys and rest of the Russia Federation. The average BMI is (20.20 ± 0.04) kg/m2 (girls – (20.32 ± 0.07), boys – (20.08 ± 0.06) kg/m2). The urban lifestyle in Tomsk Region leads to boys obesity. Conclusion. The study revealed the regional physical growth and development characteristics. Anthropometric data in Tomsk region adolescents are higher than the same data in RF.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Послеродовая депрессия - центральная проблема охраны психического здоровья раннего материнства","authors":"N. A. Kornetov","doi":"10.20538/1682-0363-2015-6-5-24","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-6-5-24","url":null,"abstract":"Perinatal mental health of the mother occupies a central position in healthcare, the same as caring for a newborn baby. Maternal depression is the lead pathology of postpartum period. Despite the high prevalence and importance to the overall development of children, most cases of depression are unappreciated, unrecognized and untreated. Inattention to issues which are related to physical and mental health of women, leads to severe negative social and economic consequences for society. Statistical comparison of the total number of pregnant women, the number of births in the United States in 2007, excluding cases of fetal loss, including still-births and miscarriages with similar Russian data allowed to calculate the approximate prevalence of postpartum depression in the same period. Presumable probability of postpartum depression is 15% in different regions of the world, and the diagnostic criteria of DSM-IV for postpartum depression are representative for comparison. Considering these assumptions, according to 2007 each year about 260,000 out of 1 mln. 600,000 of Russian women in childbirth may suffer from post-natal depression. The results have a probabilistic character. For the mothers the consequences of unrecognized and untreated depression after childbirth are the most frequent. It should be seen as a depressive episode or recurrent depressive disorder which has a singular coloring due to the appearance in the peak period of reproductive age of women. Postpartum depression may increase the possibility of occurrence of relapse of a depressive disorder as well as the transition to a state of chronic depression. Alcoholism or drug use is a common complication of depression; the risk of suicide increases, especially during the time of reducing the severity of the most severe symptoms of depression, though it is below the prevalence of suicide among the population. Particular attention should be paid to such symptoms as instability in mood and irritability as during the postpartum depression and in its residual period. They can cause child abuse. This paper also presents current data on the epidemiology, etiology, risk factors for postpartum depression, its clinical manifestations, the influence of untreated maternal depression on child development, therapy and educational modules to spread multidisciplinary and inter-agency approach in perinatal mental health problems.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ФАРМАКОЭПИДЕМИОЛОГИЧЕСКИЙ И ФАРМАКОЭКОНОМИЧЕСКИЙ АНАЛИЗ АНТИБАКТЕРИАЛЬНОЙ ТЕРАПИИ ЭНДОМЕТРИТА НА ГОСПИТАЛЬНОМ ЭТАПЕ","authors":"L. Y. Chernikova, M. Belousov","doi":"10.20538/1682-0363-2015-6-81-86","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-6-81-86","url":null,"abstract":"Pharmacoepidemiological and pharmacoeconomical analysis of endometrit drug therapy at special treatment-and-prophylactic institutions of the city of Tomsk. Estimate the intensity of the appointment of antibacterial drugs endometrit therapy using the methodology of the WHO ATC/DDD, calculated indicators of the intensity of the consumption of drugs in the course of treatment per patient. It was shown that 70% of the established daily dose had to beta-lactam antibiotics and macrolide. For the most common options for antibiotic therapy established nosology of the indicators of clinical efficacy. The calculation of the cost of the schemes of antibiotic therapy, which showed that the cost of treatment is maximal during therapy with ceftriaxone + clarithromycin (4902 RUR); further descending follow: amoxicillin / clavulanic acid + roxithromycin (4658 RUR); benzylpenicillin and gentamicin (4231 RUR). Economic efficiency of antibacterial treatments endometritis a “cost – effectiveness”. The cost of the patient, achieved remission, made during therapy with amoxicillin/clavulanic acid and roxithromycin (5416 RUR), During therapy with ceftriaxone and clarithromycin (6052 RUR), the treatment of benzylpenicillin and gentamicin (14420 RUR). Pharmacoeconomic evaluation results showed that the least acceptable scheme of antibacterial therapy of endometrit in the hospital is the combination of benzyl penicillin and gentamicin. Тhe antibiotic therapy for endometrit may be recommended by a combination of amoxicillin / clavulanic acid and roxithromycin and clarithromycin and ceftriaxone, for which there was no statistically significant differences in clinical efficacy and cost of antibiotic therapy.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2015-12-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}