Byulleten Sibirskoy Meditsiny最新文献

{"title":"Оптимальные режимы базис-болюсной инсулинотерапии у подростков с сахарным диабетом 1-го типа","authors":"G. A. Galkina, A. A. Voropay, M. Levkovich, S. V. Vorobiov, M. V. Komkova, N. V. Morozova","doi":"10.20538/1682-0363-2015-5-15-21","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-5-15-21","url":null,"abstract":"This study was aimed to determine peculiarities in regimens of the pump insulin therapy and to reveal the optimal basal-to-bolus insulin ratio that are necessary for achieving optimal glycemic control in adoles-cents with type 1 diabetes mellitus (T1DM).  82 adolescents at the age of 14–18 with T1DM, using continuous subcutaneous insulin infusion (CSII) from 5 months to 7.5 years were monitored with continuous glucose monitoring (CGM) system «Guar-dian Real Time» or CGM system, built in MiniMed Paradigm Revel System 722 (Medtronic Minimed, USA). Assessing the quality of glycaemic control was based on the level of glycated haemoglobin (HbA1c). The results of CGM were reviewed and average for 3 days performances: total daily dose of insulin, dose of basal and bolus insulin, basal-to-bolus insulin ratio, carbohydrate content of the meal, expressed in BE, carbohydrate ratio, insulin sensitivity factor were determined. The patients were subdivided into 2 groups: group 1 – adolescents with the optimal/suboptimal glycemic control ( n = 55), 2 – adolescents with long-standing poorly controlled T1DM ( n = 27). Average total daily dose of basal insulin (U in a day, U per kg in a day) in adolescents group 1 was significantly higher, com-pared with patients in group 2 ( р = 0.043; р = 0.038 respectively). Patients in group 2 received more car-bohydrates with a meal intake and had higher doses of average total daily bolus insulin. The average ba-sal-to-bolus ratio from group 1 patients was 51/49%, compared with group 2 patients – 45/55% ( р = 0.026).  An important condition for achieving optimal glycemic control is a high level of compliance and skills of adolescents. Optimal well-balanced basal-to-bolus insulin ratio in adolescents with T1DM on CSII, which can provide improvements in blood glucose management and reducing the risk of complications of the disease, is 51/49%.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"25 1","pages":"15-21"},"PeriodicalIF":0.2,"publicationDate":"2015-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ИММУНОЛОГИЧЕСКИЕ И МОРФОЛОГИЧЕСКИЕ ПРЕДИКТОРЫ КЛИНИЧЕСКОЙ ГЕТЕРОГЕННОСТИ ПАЦИЕНТОВ С БОЛЕЗНЬЮ ГРЕЙВСА (ПО РЕЗУЛЬТАТАМ ИССЛЕДОВАНИЯ ОПЕРАТИВНОГО МАТЕРИАЛА ЩИТОВИДНОЙ ЖЕЛЕЗЫ)","authors":"Татьяна Владимировна Саприна, Т. С. Прохоренко, Наталья Владимировна Рязанцева, Ирина Николаевна Ворожцова, С Э Мартынова, Анна Николаевна Дзюман, Анастасия Павловна Зима, О. С. Попов, Игорь Альбертович Хлусов, Карине Тимуровна Касоян, Ирина Петровна Шабалова","doi":"10.20538/1682-0363-2015-1-81-91","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-1-81-91","url":null,"abstract":"Very little research is devoted to the study of communication systemic immunological changes and local immunological changes in the tissue of the thyroid in autoimmune thyrophaties. The goal of the research was to establish immunologic and morphologic predictors of clinical course and functional outcomes of Graves’s disease (GD). Material and methods. We examined 45 patients with GD (14 men and 31 women) aged 18–55 years (47.0 (35.0–53.0)) years, matching the following criteria: a verified diagnosis GD, accommodation in Tomsk oblast and the Tomsk not less than 10 years, the patient's consent for the study. The control group included 30 people, with an average age of (45.3 ± 5.6) years and was comparable by age and sex with GD patients. The study included: definition of the standard for GD hormonal and serological profile (free T4, free T3, and TSH, antibodies to TPO, antibodies to the TSH receptor), the cultivation of mononuclear leukocytes in complete culture medium within 24 hours with subsequent determination of interleukins concentrations (IL-2, IL-4, TNF-alpha) in culture medium using enzyme-linked immunosorbent assay, determination of the number of blood cells carrying membrane-bound receptors to IL-2, IL-4, TNF-R1 by flow laser cytometry on cytometer BD FACS Canto tmΙΙ (USA) using labeled monoclonal antibody, the standard postoperative histological examination of thyroid gland tissue samples and immunohistochemical detection in samples of thyroid tissue receptors to IL-2, IL-4, TNF-alpha. Results. On the basis of the received results it is possible to allocate 2 clinical-immunologic and morphologic cluster of autoimmune hyperthyroidism syndrome in patients with clinical diagnosis of GD. The first includes the formation of 1 and 2 histological options GD (minimally expressed monocytes infiltration, lack of oncocytic transformation of thyroid epithelium), with some clinical characteristics (persistent and pronounced hyperthyroidism, the large size of goiter, higher titer of receptor TSH-antibody and smaller TPO-antibody, diffuse nature of the lesion), and the second – is represented by 3d histological option with oncocytic restructuring of follicular epithelium, expressed the monocyte/macrophage infiltration with the TNF-RI expression and clinical patterns, including: the older age group of patients, the smaller size of goiter, the emergence of “pseudo nodes” ultrasound, reflecting the presence of lymphoid follicles-infiltrates, more lenient for hyperthyroidism. Probably, that the 2nd cluster is a combination of “classical GD” with autoimmune thyroiditis, however, a set of clinical and laboratory-instrumental signs led to the fact that these patients were in the group of GD patients. Conclusion. This approach (combining study of indicators of systemic and local tissue-specific autoimmune inflammation) is a promising from the point of view of separate parts coverage in the autoimmune thyroids diseases pathogenesis, approximating researchers t","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"14 1","pages":"81-91"},"PeriodicalIF":0.2,"publicationDate":"2015-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"К ВОПРОСУ ОБ ИШЕМИЧЕСКОЙ ДИСФУНКЦИИ МИОКАРДА","authors":"В. В. Калюжин, Александр Трофимович Тепляков, Инна Давидовна Беспалова, Е. В. Калюжина","doi":"10.20538/1682-0363-2014-6-57-71","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-6-57-71","url":null,"abstract":"The authors of the review have analyzed papers published on the problem of ischemic myocardial dysfunction. They begin with a definition of the term “ischemia” (derived from two Greek words:  isch ō , meaning to hold back, and haima, meaning blood) - a condition at which the arterial blood flow is insufficient to provide enough oxygen to prevent intracellular respiration from shifting from the aerobic to the anaerobic form. The poor rate of ATP generation from this process causes a decrease in cellular ATP, a concomitant rise in ADP, and ultimately, to depression inotropic (systolic) and lusitropic (diastolic) function of the affected segments of the myocardium. But with such simplicity of basic concepts, the consequences of ischemia so diverse. Influence of an ischemia on myocardial function so unequally at different patients, which is almost impossible to find two identical cases (as in the case of fingerprints). It depends on the infinite variety of lesions of coronary arteries, reperfusion (time and completeness of restoration of blood flow) and reactions of a myocardium which, apparently, has considerable flexibility in its response. Ischemic myocardial dysfunction includes a number of discrete states, such as acute left ventricular failure in angina, acute myocardial infarction, ischemic cardiomyopathy, stunning, hibernation, pre- and postconditioning. There are widely differing underlying pathophysiologic states. The possibility exists that several of these states can coexist.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"13 1","pages":"57-71"},"PeriodicalIF":0.2,"publicationDate":"2015-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Психологические механизмы формирования девиаций в период подготовки к материнству","authors":"S. A. Moreva, A. V. Silaeva, A. N. Kornetov, Ye. N. Borodina, A. Y. Yankovskaya, N. I. Pryadukhina, N. E. Golovakha, V. B. Obukhovskaya","doi":"10.20538/1682-0363-2015-1-126-134","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-1-126-134","url":null,"abstract":"The article presents a social-psychological indicators of stress, coping mechanisms, rigidity and psychological component gestational dominant as risk factors predisposing to deviations in the context of preparedness for motherhood, marked psychological characteristics of pregnant women main group. Material and methods. The study was conducted on the basis of obstetric clinics SSMU, prenatal maternity hospital number 4 and the Centre for Medical Prevention (Cabinet crisis pregnancy). Total was attended by 52 women aged 18 to 44 years, at different stages of pregnancy – from 5 to 39 weeks. Methodological apparatus consisted of a structured interview questionnaire “Medical and social data of the pregnant woman” methodology for determining the stress and social adaptation of Holmes and Rage (1967), a questionnaire of coping R. Lazarus and S. Folkman (WCQ, 1988), Tomsk questionnaire rigidity G.V. Zalewski (TORZ, 1987), test on pregnant I.V. Dobryakova (1996). Data processing was carried out using statistical methods Spearman rank correlation coefficient, nonparametric Mann–Whitney U and Kruskal–Wallis H and φ * – Fisher's angular transformation. Results. Significant psychological factors that may influence the formation of readiness for motherhood among women of the main group can be considered an unplanned pregnancy (65%), and also its not gelendost (35%). Studies of stress resistance was detected in pregnant women from the main group low stress levels (88%), and only 12% have a high degree. Most of the women from the сomparison group reverse the situation 64% have a high degree of stress, this suggests that the presence of previously state miscarriage is for this group of stress. On the formation of readiness for motherhood affects not only the presence of stressful situations, butalso how the woman in their lives. Using U-test Mann–Whitney, were statistically significant differences were observed among the main group and сomparison group in the following coping strategies: selfcontrol (p ≤ 0.0014), the search for social support (p ≤ 0.0015), accepting responsibility (p ≤ 0.04), and planning solutions to the problems (p ≤ 0.00016). These differences are considered as one of the risk factors for deviant motherhood main group. In contrast to the сomparison group, where 62% of pregnant women with the optimal type PKGD, main group optimal type PKGD observed only in 38% of the respondents, which indicates that the risk of deviations in the structure of psychological readiness. Conclusion. Risk factors such as social disadvantage, the planned abandonment of a child, the tendency to rigid behavior, inefficient use of coping strategies and low level of optimal psychological component gestational dominant testify about the possible psychological unpreparedness for the upcoming event to become a mother and as a consequence to the development of deviant motherhood.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"14 1","pages":"126-134"},"PeriodicalIF":0.2,"publicationDate":"2015-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Семиотика, диагностика и тактика ведения терапии депрессивного расстройства в клинической медицине","authors":"Н. А. Корнетов","doi":"10.20538/1682-0363-2014-3-5-24","DOIUrl":"https://doi.org/10.20538/1682-0363-2014-3-5-24","url":null,"abstract":"Study objectives are dedicated to brief synthesized establishment of diagnostics general standard, management and therapy of major depressive disorders (MDD) in clinical medicine to provide education in medical practice. Study methods are based on short-term, medium-term and long-term educational programs in 24 Russian and Ukraine cities, which were based on original educational programs under the direction of World Psychiatric Association (WPA) and International Committee For Prevention and Treatment of Depression (PTD). There, about 1450 doctors of different occupations were acquainted with the detection, management and treatment of MDD. The Russian version of WPA/PTD programs was created. The program of education included 4 modules. The Core module included an overview of the epidemiology, impact, concepts and classification, and etiology of depressive disorders as well as their recognition, diagnosis, and management in the primary care setting. The second module focused on depressive disorders in physical illness and covered those major illnesses for which is reasonable evidence for an association with depressive disorders. The third module included the development of the depressive disorders in older persons. The forth module included training physicians in mental health skills. 39 theme improvements for 858 primary care setting physicians within the framework of faculty training program of physicians’ development were the part of other programs of physicians’ occupations. Results. A number of highlights were included in the general algorithm of the educational programs. The creation of optimum «physician-depressive patient» contact demands a number of new skills to establish effective communication. These skills involve training of meeting of depressive patient and physician, the ability to follow a certain communication style; identify emotional, cognitive, psychomotor and nonverbal patterns of behavior. Besides that, the education included adherence to therapy and therapeutic alliance during the period of informed agreement. There was an education of fluent grasp of medicaments, which are the first choice in therapy. Integration of this knowledge is done during the periods of repeated interactive discussions of antidepressants’ effectiveness in depression therapy which is based on three-phased MDD therapy model. The process of working out the depressive patients’ management was based on systematization and diagnostic of depression disorders (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, or International Classification of Diseases, Revision 10); detailed discussions of manifestation and thorough depression symptomatology; management approaches in depression disorders, different in manifestation. Conclusion. The basis of physicians' education was the idea that depressive disorder in holistic approach can't be considered as an independent psychiatric disease in its mild and moderate forms of manifestation. Depression","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"13 1","pages":"5-24"},"PeriodicalIF":0.2,"publicationDate":"2015-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Неинвазивная оценка жесткости сосудистой стенки у здоровых подростков, имеющих факторы риска развития артериальной гипертензии","authors":"G. P. Filippov, K. V. Boronenko, I. V. Plotnikova, Ye. S. Sitkova","doi":"10.20538/1682-0363-2015-4-82-86","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-4-82-86","url":null,"abstract":"Objective. To evaluate the main indicators characterizing the rigidity of the vascular wall in healthy ado-lescents with such risk factors (RF) for arterial hypertension (AH) as a family history on hypertension and smoking. Identify changes in the initial elastic-elastic properties of the arteries at the preclinical stage of development of hypertension. Material and methods. It was formed two groups of comparison. Age studied from 13 to 17 years (mean age (15.00 ± 0.31) years). The first group consisted of 30 healthy adolescents whose parents suffer from hypertension from a young age. The second group consisted of 30 healthy smokers teenager from healthy parents. The control group consisted of 30 healthy adolescents from healthy parents. Determines the basic stiffness of the vascular wall: PWV, CAVI, SAI. Results. A significant in crease in the indicators characterizing the rigidity of the vascular wall in the two comparison groups relative to the control. PWV: 6,89 ± 0,56 (first group), 7.13 ± 0.55 (second group) and 5.5 ± 0.41 (control), p < 0.05.L-CAVI: 5,46 ± 0,39 (first group), 5.84 ± 0.61 (second group) and 4.32 ± 0.41 (control), p < 0.05.R-CAVI: 5,63 ± 0,39 (first group), 5.89 ± 0.56 (second group) and 4.49 ± 0.41(control), p < 0.05. R-AI: 0,89 ± 0,09 (first group), 0.95 ± 0.12 (second group) and 0.62 ± 0.1 (control), p < 0.05. Smoking teenagers and adolescents with family history of hypertension, there are changes in the initial stiffness of the vessel wall, which requires the allocation of at-riskfor the development of hypertension and prevention activities at the preclinical stage of development ofthe disease.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"14 1","pages":"82-86"},"PeriodicalIF":0.2,"publicationDate":"2015-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Электрокинетические свойства, растворение in vitro, потенциальная биосовместимость оксидных и оксинитридных пленок титана для сердечно-сосудистых стентов","authors":"I. A. Khlusov, V. Pichugin, A. A. Pustovalova, M. E. Konischev, A. N. Dzyuman, Matthias Epple, Mathias Ulbricht, E. Cicinskas, V. S. Gulaya, V. V. Vikhareva","doi":"10.20538/1682-0363-2015-2-55-66","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-2-55-66","url":null,"abstract":"A state of titanium oxide and oxynitride coatings on L316 steel has been studied before and after their contact with model biological fluids. Electrokinetic investigation in 1 mmol potassium chloride showed significant (more than 10 times) fall of magnitude of electrostatic potential of thin (200–300 nm) titanium films at pH changing in the range of 5–9 units during 2 h. Nevertheless, zeta-potential of all samples had negative charge under pH > 6.5. Long-term (5 weeks) contact of samples with simulated body fluid (SBF) promoted steel corrosion and titanium oxide and oxynitride films dissolution. On the other hand, sodium and chloride ions precipitation and sodium chloride crystals formation occurred on the samples. Of positive fact is an absence of calcification of tested artificial surfaces in conditions of long-term being in SBF solution. It is supposed decreasing hazard of fast thrombosis and loss of materials functional properties. According to in vitro experiment conducted, prospective biocompatibility of materials tested before and after their contact with SBF lines up following manner: Ti–O–N (1/3) > Ti–O–N (1/1), TiO2 > Steel. It may be explained by: 1) the corrosion-preventive properties of thin titanium oxide and oxynitride films; 2) a store of surface negative charge for Ti–O–N (1/3) film; 3) minor augmentation of mass and thickness of titanium films connected with speed of mineralization processes on the interface of solution/solid body. At the same time, initial (before SBF contact) differences of samples wettability became equal. Modifying effect of model biological fluids on physicochemical characteristics of materials tested (roughness enhancement, a reduction or reversion of surface negative potential, sharp augmentation of surface hydrofilicity) should took into account under titanium oxide and oxynitride films formation and a forecast of their optimal biological properties as the materials for cardiovascular stents.","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"44 1","pages":"55-66"},"PeriodicalIF":0.2,"publicationDate":"2015-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"OPTIMIZATION OF DIAGNOSTIC IMAGING IN BREAST CANCER","authors":"S. Velichko, Yury Tyukalov, I. Frolova, D. G. Bukharin, Ye. Ye. Bober","doi":"10.20538/1682-0363-2015-4-12-16","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-4-12-16","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"14 1","pages":"12-16"},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"THE ROLE OF PROTEIN OXIDATIVE MODIFICATION IN REDOX-REGULATION OF CASPASE-3 ACTIVITY IN BLOOD LYMPHOCYTES DURING OXIDATIVE STRESS IN VITRO","authors":"O. L. Nosareva, Y. A. Stepovaya, N. Ryazantseva, Ye. V. Shakhristova, O. Vesnina, V. V. Novitsky","doi":"10.20538/1682-0363-2015-14-6-61-67","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-14-6-61-67","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"14 1","pages":"61-67"},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"INTERNATIONAL ASPECTS OF EDUCATION AND TRAINING IN TELEMEDICINE","authors":"R. Engelbrecht, A. Hasman, J. Mantas, L. Nicholson","doi":"10.20538/1682-0363-2015-3-63-67","DOIUrl":"https://doi.org/10.20538/1682-0363-2015-3-63-67","url":null,"abstract":"","PeriodicalId":43691,"journal":{"name":"Byulleten Sibirskoy Meditsiny","volume":"14 1","pages":"63-67"},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67685595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}