A. Sahraian, M. Mokhtari, A. Moaref, V. Rezaee, Ebrahim Moghimi, A. Mani
{"title":"Hypertensive Patients and Normotensive Individuals: Differences in Anger Inventory","authors":"A. Sahraian, M. Mokhtari, A. Moaref, V. Rezaee, Ebrahim Moghimi, A. Mani","doi":"10.17795/ICRJ-9(4)216","DOIUrl":"https://doi.org/10.17795/ICRJ-9(4)216","url":null,"abstract":"Background: Hypertension (HTN) is a common condition with increasing prevalence rate. Hypertensive patients have a high prevalence of mental disorders, including anger. Objectives: The present study aimed to investigate the score of anger in hypertensive patients in comparison to the individuals with normal blood pressure in Shiraz. Patients and Methods: This case-control study was conducted on 100 patients with HTN and 107 normal controls with the mean age of 52.48 and 53.78 years, respectively. These patients had referred to Shiraz HTN clinic in 2013. All the patients completed the Multidimensional Anger Inventory (MAI) and the results were analyzed using the SPSS statistical software, 2010. Results: The participants were matched regarding age and other demographic factors which might have influenced HTN. Distributions of these factors were partly similar and the differences were not significant. The HTN group obtained higher scores in all dimensions. Besides, the differences were significant in all subscales, except for anger. Conclusions: In line with the previous researches, the present study indicated that high level of aggression was correlated to high blood pressure. Therefore, it is necessary to have psychological interventions along with other interventions for hypertensive patients. Overall, this research confirmed biopsycho approach to psychosomatic diseases.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"9 1","pages":"216-219"},"PeriodicalIF":0.2,"publicationDate":"2015-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Fazlinezhad, M. Hami, M. Shakeri, Hoda Khatibi-Moghaddam, Maliheh DadgarMoghadam, Majid Khadem-Rezaiyan, S. Soflaei
{"title":"The Relationship between Serum Hemoglobin and Creatinine Levels and Intra-Hospital Mortality and Morbidity in Acute Myocardial Infarction","authors":"A. Fazlinezhad, M. Hami, M. Shakeri, Hoda Khatibi-Moghaddam, Maliheh DadgarMoghadam, Majid Khadem-Rezaiyan, S. Soflaei","doi":"10.17795/ICRJ-9(4)220","DOIUrl":"https://doi.org/10.17795/ICRJ-9(4)220","url":null,"abstract":"Background: Studies have shown that Glomerular Filtration Rate (GFR) and Hemoglobin (Hb) concentrations are two predictive values for ST-elevation Myocardial Infarction (MI) mortality. Objectives: This study aimed to investigate the relationship between GFR and Hb concentrations and intra-hospital mortality and electrocardiographic (ECG) and echocardiographic abnormalities in ST-elevation MI patients admitted to a highly equipped hospital in Mashhad. The results will help define some factors to manage these patients more efficiently. Patients and Methods: This descriptive study aimed to assess the relationship between Hb and GFR concentrations and mortality and morbidity among 294 randomly selected patients with ST-elevation MI. Echocardiography, ECG, and routine laboratory tests, including Hb and creatinine, were performed for all the patients. Then, the data were entered into the SPSS statistical software, version 16 and were analyzed using chi-square, t-test, and ANOVA. P < 0.05 was considered as statistically significant. Results: Intra-hospital mortality rate was 10.5%. Besides, the results showed higher levels of serum blood sugar (P < 0.001), higher levels of creatinine (P < 0.001), lower levels of GFR (P < 0.001), lower ejection fraction (P < 0.001), higher grades of left ventricular diastolic dysfunction (P = 0.002), and lower mean Hb concentration (P = 0.022) in the dead compared to the alive cases. Besides, the patients with mechanical complications had lower Hb levels (P = 0.008). The results showed no significant relationship between creatinine level and mechanical and electrical complications (P = 0.430 and P = 0.095, respectively). However, ejection fraction was significantly associated with GFR (P = 0.016). Conclusions: According to the results, low levels of Hb and GFR could predict mortality caused by ST-elevation MI and ECG abnormalities could notify intra-hospital death. Moreover, lower Hb levels were associated with mechanical complications and could be used as a parameter for diagnosis of high-risk patients.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"9 1","pages":"220-225"},"PeriodicalIF":0.2,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hashem Danesh Sani, Moosa Karami Kharat, Mohammad Vejdanparast, A. Eshraghi, Alireza, Abdollahi Moghaddam, Hamid Eshraghi
{"title":"Oral Selenium: Can It Prevent Contrast-Induced Nephropathy Following Coronary Angiography and Angioplasty","authors":"Hashem Danesh Sani, Moosa Karami Kharat, Mohammad Vejdanparast, A. Eshraghi, Alireza, Abdollahi Moghaddam, Hamid Eshraghi","doi":"10.17795/ICRJ-9(4)226","DOIUrl":"https://doi.org/10.17795/ICRJ-9(4)226","url":null,"abstract":"Background: Alteration of kidney function called Contrast-Induced Nephropathy (CIN) is commonly encountered in diagnostic and interventional cardiology procedures. It results in considerable morbidity and mortality besides imposing significant costs on the healthcare system. Today, it is accounted as the third cause of hospital-acquired acute renal failure. Objectives: Considering anti-oxidant and free radical scavenging properties of selenium and the role of free radicals in CIN, the present study aimed to investigate the effects of oral selenium (in the form of Se-yeast capsule) on preventing or decreasing the rate of CIN in patients undergoing angiography and angioplasty. Patients and Methods: This prospective, non-randomized, single-blind, single-center clinical trial was conducted on 175 consecutive patients admitted for elective coronary angiography (N = 105) or angioplasty (N = 70). Selenium was prescribed as a single dose of 200 micrograms the day before and after the procedure. Routine hydration based on the ward protocol was administered for all the patients. For the control group, the researchers made use of the data of another survey performed in the same hospitals for determining the prevalence of CIN a year before. The data were analyzed using student's t-test and logistic regression analysis and P < 0.05 was considered as statistically significant. Results: Based on the results of student's t-test, the mean difference between the two groups was significant only in hematocrit levels. The incidence of CIN was 9% in the selenium group compared to 22% in the control group (P = 0.027). There was no case of in-hospital mortality and none of the CIN patients required renal replacement therapy during hospitalization. Conclusions: Prophylactic selenium administration may significantly reduce the incidence of CIN.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"9 1","pages":"226-230"},"PeriodicalIF":0.2,"publicationDate":"2015-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68175745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Abtahi, M. Zibaeenezhad, Fatemeh Shafazadeh, M. Tahamtan
{"title":"Tissue Doppler Findings in Patients with Pulmonary Arterial Hypertension","authors":"F. Abtahi, M. Zibaeenezhad, Fatemeh Shafazadeh, M. Tahamtan","doi":"10.17795/ICRJ-10(03)113","DOIUrl":"https://doi.org/10.17795/ICRJ-10(03)113","url":null,"abstract":": Background: \u0000Pulmonary hypertension is an untreatable condition with poor prognosis and factors such as more elevated pulmonary arterial systolic pressure and right ventricular dysfunction are associated with a worse outcome. Objectives: \u0000Considering the limitations of the current modalities, this study aimed to find the relationship between tissue Doppler-derived systolic and diastolic parameters and elevated pulmonary arterial pressure in order to assess the routine application of tissue Doppler imaging in evaluation of pulmonary arterial hypertension. Patients and Methods: \u0000This study was conducted on 100 inpatient and outpatient individuals referred to the Department of Echocardiography in Shahid Faghihi hospital, Shiraz, Iran from July 2012 to March 2013. The individuals who had preserved right ventricular function in the presence of pulmonary arterial hypertension were included in the case group. On the other hand, the patients who did not have echocardiographic signs of pulmonary arterial hypertension were enrolled into the control group. All the patients underwent a complete transthoracic echocardiogram including 2-dimensional, color flow, and spectral Doppler as well as tissue Doppler imaging using a vivid E9 system, and the desired systolic and diastolic parameters were recorded. The relationship among these parameters was evaluated by independent sample t-test using the SPSS statistical software, version 16. Besides, P Results: \u0000The mean time to peak strain was significantly longer in the case group (203.98 ± 47.54 milliseconds) compared to the controls (81.20 ± 25.76 milliseconds). The mean early diastolic tricuspid inflow velocity/early diastolic tricuspid annulus velocity (E/E’a) ratio was also significantly higher in the case group (10.24 ± 6.19) compared to the controls (4.70 ± 0.80). In contrast, Isovolumic Contraction (IVC) acceleration time/IVC time ratio was reduced in the case group (0.44 ± 0.09) in comparison to the control patients (0.56 ± 0.05). Conclusions: \u0000In conclusion, our results suggested that increasing degrees of pulmonary artery systolic pressure affected timing of some tissue Doppler-derived intervals within the cardiac cycle, including IVC time, time to peak systolic myocardial velocity (Sm), and time to peak strain. Therefore, tissue Doppler imaging could be used in assessment of patients with suspected pulmonary arterial hypertension.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"10 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2015-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68174134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra-Hospital Outcomes in ST Elevation Myocardial Infarction: Comparison of Diabetic and Non-Diabetic Patients","authors":"T. Kazemi, F. Shafiee, T. Shafiee","doi":"10.17795/ICRJ-9(4)251","DOIUrl":"https://doi.org/10.17795/ICRJ-9(4)251","url":null,"abstract":"","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"9 1","pages":"251-252"},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68176737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Rajan, V. Krishnakumar, C. G. Bahuleyan, P. Nair
{"title":"Mitral Prosthetic Valve Obstruction and Its Complications","authors":"R. Rajan, V. Krishnakumar, C. G. Bahuleyan, P. Nair","doi":"10.17795/ICRJ-9(4)247","DOIUrl":"https://doi.org/10.17795/ICRJ-9(4)247","url":null,"abstract":"Prosthetic Valve Obstruction (PVO) is a serious complication which is associated with increased morbidity and mortality. This could result from thrombus formation, development of pannus, or a combination of both. Patients with this complication often present with symptoms and signs of heart failure, systemic embolism, acute cardiovascular collapse, and sudden death. Transesophageal echocardiography and cine fluoroscopy play a vital role in diagnosis of this potentially lethal condition. Herein, we reported a 56-year-old male patient who presented with severe heart failure and was found to have obstructed ATS27 bileaflet mitral prosthetic valve. Thrombolysis and redo surgery are two important options for treating this condition although guidelines for choosing between the two are not very definite.","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"22 1","pages":"247-250"},"PeriodicalIF":0.2,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68176629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamad Hossein Nikoo, Mohamad Vahid Jorat, Amir Aslani
{"title":"Focal treatment for genetic disorders (a fairy tale or a true story?).","authors":"Mohamad Hossein Nikoo, Mohamad Vahid Jorat, Amir Aslani","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"8 4","pages":"137-8"},"PeriodicalIF":0.2,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e2/25/icrj-08-137.PMC4302498.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32997850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ali Maleki, Negin Rashidi, Hamidreza Aghaei Meybodi, Mahdi Montazeri, Mohammad Montazeri, Farid Falsafi, Reza Ghanavati, Saeid Forughi, Farshid Alyari
{"title":"Metabolic syndrome and inflammatory biomarkers in adults: a population-based survey in Western region of iran.","authors":"Ali Maleki, Negin Rashidi, Hamidreza Aghaei Meybodi, Mahdi Montazeri, Mohammad Montazeri, Farid Falsafi, Reza Ghanavati, Saeid Forughi, Farshid Alyari","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>There is evidence that inflammation may be involved in pathogenesis of MetS. Inflammatory biomarkers are moving to the forefront as the potent predictors of MetS.</p><p><strong>Objectives: </strong>The present study aimed to evaluate the association between MetS and some inflammatory biomarkers.</p><p><strong>Patients and methods: </strong>This community-based cross-sectional study was conducted on 800 subjects aged above 35 years selected through random sampling in Borujerd (west of Iran) from 2011 to 2013. MetS was defined based on ATP III criteria and the subjects were divided into two groups (MetS and non-MetS groups). Waist circumference and Body Mass Index (BMI) were calculated. In addition, blood samples were taken and C-Reactive Protein (CRP), lipid profile, Fasting Blood Sugar (FBS), and Bleeding Time (BT) were measured. Then, the correlations between MetS and the above-mentioned variables were estimated. After all, the data were entered into the SPSS statistical software (v. 17) and analyzed using T-test, chi-square, median test, and spearman's rank correlation.</p><p><strong>Results: </strong>In this study, 344 subjects (43%) met the ATP III criteria. The results showed a significant difference between MetS and non-MetS groups regarding BMI, white blood cell, total cholesterol, LDL, platelet, and high-sensitivity CPR (hs-CRP) (P < 0.0001, P = 0.040, P < 0.0001, P < 0.0001, and P = 0.045, respectively). Besides, waist circumference, Triglyceride (TG), FBS, and systolic and diastolic blood pressure were significantly higher, while HDL was significantly lower in the MetS group (P < 0.0001).</p><p><strong>Conclusions: </strong>The incidence rate of MetS in our survey was higher compared to the previous reports. In addition, this incidence rate was higher in females in comparison to males. The results also showed a significant correlation between inflammatory biomarkers and MetS and that the higher levels of hs-CRP were associated with higher rate of MetS.</p>","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"8 4","pages":"156-60"},"PeriodicalIF":0.2,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/fd/99/icrj-08-156.PMC4302503.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32997775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"QT Dispersion after Thrombolytic Therapy.","authors":"Saeed Oni Heris, Behzad Rahimi, Gholamreza Faridaalaee, Mojgan Hajahmadi, Hojjat Sayyadi, Bahman Naghipour","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>QT dispersion (QTd) is equal to longer QTc minus shorter QTc measured by 12-lead electrocardiogram (ECG). QTd reflects inhomogeneity in repolarization of ventricular myocardium and because of easy and fast measurement of QTd, it can be used to predict high-risk patients for dysrhythmia after Acute Myocardial Infarction (AMI).</p><p><strong>Objectives: </strong>This study aimed to assess the effect of thrombolytic therapy on QTd before and 1 hour and 4 days after beginning of thrombolytic therapy.</p><p><strong>Patients and methods: </strong>The patients with chest pain and ST Elevated Myocardial Infarction (STEMI) that underwent thrombolytic therapy were enrolled into this study. Streptokinase was the thrombolytic agent in all the patients. Standard 12-lead (ECG) was evaluated before beginning of thrombolytic therapy (QTd 1) and 1 hour (QTd2) and 4 days (QTd3) after thrombolytic therapy. First, ECG was magnified × 10 for exact calculation of QT and QTd. After all, the variables were compared using one-way analysis of variance (ANOVA). Besides, P ≤ 0.05 was considered as statistically significant.</p><p><strong>Results: </strong>This study was conducted on 160 patients. The results revealed no significant differences among QTd 1, QTd 2, and QTd 3 (P > 0.05). At inferior AMI, however, a significant difference was observed among QTd1, QTd2, and QTd3 (P = 0.031).</p><p><strong>Conclusions: </strong>Thrombolytic therapy had no significant effects on QTd. Thus, thrombolytic therapy does not increase the risk of arrhythmia.</p>","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"8 4","pages":"161-5"},"PeriodicalIF":0.2,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/d6/ca/icrj-08-161.PMC4302504.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"32997776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ibrahim Altun, Goksel Guz, Fatih Akin, Nuri Kose, Ilknur Altun, Zeki Yuksel Gunaydin, Cem Sahin
{"title":"Improvement of dilated cardiomyopathy with methylprednisolone in a patient with multiple fibrosclerosis.","authors":"Ibrahim Altun, Goksel Guz, Fatih Akin, Nuri Kose, Ilknur Altun, Zeki Yuksel Gunaydin, Cem Sahin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Multifocal fibrosclerosis is a rare syndrome of unknown cause that is characterized by fibrosis involving multiple organ systems. Definitive diagnosis can only be made based on biopsy findings. In this case, the biopsy specimen of the patient demonstrates pulmonary hyalinated granuloma or sclerosing mediastinitis. There are few reports of multiple fibrosclerosis with heart failure. Here, we reported a case of retroperitoneal fibrosis with massive mediastinal involvement extending to pleura and pericardium causing pleuro- pericardial effusion with dilated cardiomyopathy. Systolic dysfunction was improved and pericardial effusion disappeared with methylprednisolone treatment. </p>","PeriodicalId":43653,"journal":{"name":"International Cardiovascular Research Journal","volume":"8 4","pages":"178-80"},"PeriodicalIF":0.2,"publicationDate":"2014-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/5c/icrj-08-178.PMC4302507.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33322144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}