Indian Journal of Occupational and Environmental Medicine最新文献

{"title":"Socio-Demographic Profile of Low Back Pain in Health Care Workers of a Tertiary Care Center of Eastern India - A Cross-Sectional Study.","authors":"Anurug Biswas, Niraj Kumar, Srutarshi Ghosh, Sanjay K Pandey, Anjani Kumar, Sanyal Kumar, Jyoti Pandey, Subha Das, Ranjeet Kumar","doi":"10.4103/ijoem.ijoem_293_24","DOIUrl":"10.4103/ijoem.ijoem_293_24","url":null,"abstract":"<p><strong>Background and aim: </strong>Majority of the healthcare workers (HCWs) globally have low back pain (LBP) at some point of time of their lives, resulting in activity limitation and sick leave. HCWs are exposed to the burden of long duty hours, poor posture, inadequate sleep hours, stress, etc., which ultimately leads to the occurrence of LBP. This study aimed to assess different factors influencing LBP among HCWs for early prevention and environmental modification.</p><p><strong>Methods: </strong>This cross-sectional observational study was conducted in a tertiary center in Eastern India. The study population was all HCWs presently working in the author's institute. Self-administered questionnaire in English and Hindi was used via Google Forms for data collection. Hard copy of the form was used for the participants unable to fill online form. The association of different variables with other influencing variables was tested using non-parametric Kruskal-Wallis, Mann-Whitney, and Chi-square tests.</p><p><strong>Result: </strong>Among 330 participants, the majority belonged to the age group of 30-39 years (47.6%), and the male-female ratio was 3:2. The significant association of pain intensity was found with gender (more in females, <i>P</i> = 0.001), body mass index (<i>P</i> = 0.001), job profile (less in doctors and paramedics, <i>P</i> = 0.021), comorbidity (maximum with hypothyroidism, <i>P</i> < 0.001), job satisfaction (less among much satisfied cases, <i>P</i> = 0.004), footwear (more pain among chappal wearers, <i>P</i> = 0.006), and vitamin D level (more pain in cases of low vitamin D level, <i>P</i> = 0.032).</p><p><strong>Conclusion: </strong>This study identified an association of increased pain intensity with female gender, both low and high BMI, nursing job, less job satisfaction, improper footwear usage, etc. The chronicity was associated with higher age, BMI, lower or no exercise, comorbidity, and low serum vitamin D.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"110-117"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cytomegalovirus Infection: Concern for Occupational, Environmental, and Nosocomial Infections?","authors":"Azra Kenarkoohi, Fatemeh Ghiasi, Hamed Azadi, Yadollah Bahrami, Saiyad Bastaminejad, Sara Rezaee, Effat Noori, Delsuz Rezaee, Shahab Falahi","doi":"10.4103/ijoem.ijoem_124_24","DOIUrl":"10.4103/ijoem.ijoem_124_24","url":null,"abstract":"<p><strong>Background: </strong>Cytomegalovirus (CMV) is the leading cause of congenital and perinatal infections, often presenting as asymptomatic at birth but later resulting in disabilities, and articular neurological disorders.</p><p><strong>Aims: </strong>The current study aims to assess the prevalence of asymptomatic CMV infection among healthcare workers at Ilam Gynecology and Obstetrics Hospital in Iran, as well as investigate the potential nosocomial transmission of CMV infection and identify any potential risk factors associated with neonatal CMV infection.</p><p><strong>Methods: </strong>This study involved 100 employees at Ilam Gynecology and Obstetrics Hospital who underwent blood and nasal swab CMV DNA testing using the real-time PCR technique.</p><p><strong>Results: </strong>The average age of the patients was 33.87 years, ranging from 24 to 52 years. Among the 100 samples, CMV DNA was detected in three blood samples (3%) (ages 26, 31, and 38 years) and one swab sample (1%) (age 31). To confirm the molecular results, the PCR products were purified and sequenced, and one case was confirmed to be an asymptomatic carrier of CMV.</p><p><strong>Conclusions: </strong>We did not find any significant correlation between CMV positivity and occupational groups. Despite the relatively low incidence of CMV DNA, especially in swab samples and the absence of evidence suggesting nosocomial transmission of CMV to the hospital staff or neonates, it is crucial to pay significant attention to primary CMV infection among healthcare workers.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"141-144"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mitigating Cognitive Failures and Unsafe Acts Through Cognitive Resilience: A Study in the Petrochemical Construction Sector of Asaluyeh, Iran.","authors":"Anahita Larestani, Donya Tayebi, Reza Esmaeili, Sayed Vahid Esmaeili, Mahnaz Shakerian","doi":"10.4103/ijoem.ijoem_138_24","DOIUrl":"10.4103/ijoem.ijoem_138_24","url":null,"abstract":"<p><strong>Background: </strong>Resilience affects the occurrence of unsafe acts, influencing occupational incidents. Understanding this impact can aid in preventing such incidents through proactive measures.</p><p><strong>Aim: </strong>This study aims to determine the relationship between cognitive resilience and cognitive failures, leading to unsafe acts.</p><p><strong>Methods: </strong>This cross-sectional study was performed on 173 construction workers employed in a petrochemical sector in Asaluyeh, Iran. The Unsafe Act questionnaire and Connor-Davidson resilience scale were utilized to collect data. Correlation analysis was used to interpret the results. The Pearson correlation test and ANOVA were employed to explore the relationships between cognitive resilience, unsafe acts, and cognitive failures.</p><p><strong>Results: </strong>The analysis revealed a high prevalence of unsafe acts, potentially compromising safety, alongside moderate levels of cognitive resilience among workers. A strong negative correlation was found between total resilience scores and unsafe acts (r = -0.701, <i>P</i> value < 0.001). Additionally, education level, near-miss history, and accidents, leading to absenteeism, were significantly related to cognitive resilience and unsafe acts (<i>P</i> value < 0.001).</p><p><strong>Conclusion: </strong>Enhancing cognitive resilience in construction workers significantly reduces unsafe acts. Given the strong correlation, training programs to boost cognitive resilience should be implemented within organizational instructions to enhance job security and reduce unsafe acts.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"160-166"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Correlation between the Quality of Work Life and Caring Nurse-Patient Interactions with Burnout among Oncology Nurses.","authors":"Marzieh Fallah, Kheizaran Miri, Mahnaz Bahrami, Hakimeh Sabeghi, Gholamreza Sharifzadeh","doi":"10.4103/ijoem.ijoem_82_24","DOIUrl":"10.4103/ijoem.ijoem_82_24","url":null,"abstract":"<p><strong>Background: </strong>Oncology units within specialized and high-stress hospital settings create significant emotional and psychological stress in nurses, which can affect their quality of work life (QWL). This study aimed to determine the correlation between QWL and caring nurse-patient interactions with burnout among oncology nurses.</p><p><strong>Methods and materials: </strong>In this correlational study, 200 oncology nurses were selected using convenience sampling. Data collection scales included the valid and reliable Maslach Burnout Inventory, the caring nurse-patient interaction questionnaire, and Brook's Quality of Nursing Work Life Questionnaire. The collected data were analyzed using SPSS₂₀ software.</p><p><strong>Results: </strong>The results showed an inverse and significant linear relationship between QWL and caring nurse-patient interactions with burnout among oncology nurses. In addition, there was a direct and significant linear relationship between QWL and nurse-patient care interactions.</p><p><strong>Conclusion: </strong>Considering the significant relationship between QWL and nurse-patient care interactions with a burnout in nurses, it seems that, according to the special mental atmosphere of oncology departments, it is necessary to have a written plan to reduce burnout in nurses.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"87-90"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep Duration and Energy Expenditure at Work in Motorcycle Taxi Drivers from Rio Branco City, Western Brazilian Amazon: A Cross-Sectional Study.","authors":"Orivaldo F de Souza, Narjara C de Araújo, Elyecleyde K da Silva Oliveira, Edson Dos Santos Farias, Francisco N C Leitão, Luiz C de Abreu","doi":"10.4103/ijoem.ijoem_229_24","DOIUrl":"10.4103/ijoem.ijoem_229_24","url":null,"abstract":"<p><strong>Background: </strong>Sleep duration disorders impact the quality of life and energy expenditure in workers. However, there is a lack of understanding about the relationship between sleep duration and energy expenditure at work among motorcycle taxi drivers.</p><p><strong>Aims: </strong>To analyze the relationship between sleep duration and energy expenditure at work in motorcycle taxi drivers.</p><p><strong>Settings and design: </strong>A cross-sectional study was conducted with 296 male motorcycle taxi drivers from Rio Branco City, western Brazilian Amazon. Methods and Material: The motorcycle taxi driver reported the number of hours daily spent sleeping on a typical day during the week. Uncorrected and corrected energy expenditures of motorcycle taxi drivers during the working day were calculated according to the 2011 Physical Activity Compendium. The metabolic equivalent (MET) was corrected for the basal metabolic rate using the equation proposed by Harris and Benedict.</p><p><strong>Statistical analysis: </strong>The relationship between sleep duration and energy expenditure at work was analyzed using fractional polynomial regression.</p><p><strong>Results: </strong>The mean sleep duration in hours was 7.4 (SD: 1.4). There was a relationship between sleep duration and corrected energy expenditure at work, with a first-degree logarithmic transformation. The nonlinear relationship between sleep duration and uncorrected energy expenditure at work was a fractional polynomial with a power of -0.5 for the first degree.</p><p><strong>Conclusions: </strong>The results suggest a nonlinear relationship between sleep duration and energy expenditure at work among motorcycle taxi drivers. Motorcycle taxi drivers with short sleep durations had high energy expenditures at work.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"91-95"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318551/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Cardiovascular Disease Risk in Young Healthcare Professionals: Insights from Q-Risk 3 Calculations.","authors":"Ramya Rangarajan, Sujatha M Premnath","doi":"10.4103/ijoem.ijoem_272_23","DOIUrl":"10.4103/ijoem.ijoem_272_23","url":null,"abstract":"<p><strong>Background: </strong>There is a global rise in cardiovascular diseases (CVD), particularly among the current generation of young adults, including the health professionals. Factors such as poor lifestyle choices, inadequate nutrition, sedentary work, and prolonged working hours contribute to occupational stress.</p><p><strong>Aim: </strong>This study aimed to investigate the prevalence of CVD risk factors in young healthcare workers aged 25-40 and assess their 10-year CVD risk using the QRISK 3 prediction algorithm.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted on 248 health workers aged 25-40 years in a tertiary care hospital in Pondicherry. Data collected include questionnaire responses for the QRISK 3 algorithm, weight, height, and two SBP readings on two different days, and blood samples for HDL-c, Fasting glucose, and Total cholesterol level.</p><p><strong>Result: </strong>Nearly 26.6% of the participants had high body mass index (BMI), 5.24% had diabetes mellitus, 16.12% had hypertension, 25.4% were found with hyperlipidemia, 6.3% had a history of light smoking, and 47.5% had a family history of CVD. Most of the risk factors except hypertension and low HDL-c showed female preponderance. Despite the high prevalence, the mean QRISK score of a 10-year risk of getting CVD among young healthcare workers is less, which is only 1.3%.</p><p><strong>Conclusion: </strong>Though the prevalence of major risk factors is high among healthcare workers other risk factors that the QRISK 3 algorithm takes into consideration were very low among the participants. The higher prevalence of metabolic risk factors emphasizes the need for the change in lifestyle behaviors of participants.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"136-140"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Pattern, Perpetrators, and Probable Mitigation Strategies for Workplace Violence Targeting Doctors in India: A Cross-Sectional Survey.","authors":"Naveen Paliwal, Pooja Bihani, Rishabh Jaju, Sadik Mohammed, Sharmili Sinha, Ankit Vyas","doi":"10.4103/ijoem.ijoem_257_24","DOIUrl":"10.4103/ijoem.ijoem_257_24","url":null,"abstract":"<p><strong>Introduction: </strong>Workplace violence (WPV) against healthcare professionals in India is alarmingly high, exceeding global averages, with emergency departments and intensive care units being high-risk areas. This study aimed to determine the prevalence and risk factors of WPV among doctors, evaluate reporting practices, assess its psychosocial impact, and evaluate existing prevention measures.</p><p><strong>Methodology: </strong>A descriptive, cross-sectional survey was conducted using a semi-structured questionnaire distributed via Google Forms through snowball sampling. The questionnaire, validated for content, included demographic information, details of WPV encountered in the past 12 months, its consequences, reporting practices, and mitigation strategies. Statistical analysis, including descriptive statistics and Spearman rank correlation, was performed using SPSS version 19.</p><p><strong>Results: </strong>Out of 658 respondents, 60.9% reported experiencing WPV, predominantly verbal abuse. Perpetrators were mainly patients' visitors, and common causes included dissatisfaction with services and poor communication. Night hours, operation theatres, ICUs, and emergency rooms were high-risk locations. A significant portion (48%) did not report incidents due to perceived inaction and lack of organizational support. WPV negatively impacted psychosocial well-being in over half of the affected doctors. Deficiencies in training and grievance redressal systems were reported, with a strong recommendation for communication skills training.</p><p><strong>Conclusion: </strong>WPV is highly prevalent among Indian doctors, with verbal abuse being the most common form. Poor communication and lack of reporting mechanisms exacerbate the issue. Integrating communication training into medical curricula and establishing robust reporting systems are crucial for mitigating WPV and supporting healthcare professionals.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"118-123"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Work-Related Stress among Healthcare Providers at Neonatal Intensive Care Unit (NICU): A Multicentric Collaborative Study from Karnataka, India.","authors":"Diksha Deepak, Mahalaxmi Korwar, Shruthi K Bharadwaj, Abhishek Somasekhara Aradhya, Anil Kallesh, Prashant S Urs, Praveen Venkatagiri, Alok Singh, Hellan Glory, Gautham M Sukumar, Akanksha Agarwal, Sheila S Mathai, Anjana Rao, Anup Itihas, C Anusree, Sreenath Sonnappa, Chinmaya Patil, Harish Thippeswamy","doi":"10.4103/ijoem.ijoem_347_24","DOIUrl":"10.4103/ijoem.ijoem_347_24","url":null,"abstract":"<p><strong>Background: </strong>Work-related stress in healthcare professionals can negatively affect the quality of healthcare delivered, particularly in high-stress environments like the Neonatal Intensive Care Units (NICU).</p><p><strong>Objectives: </strong>We examined the prevalence of work stress and common stressors among healthcare providers in the NICU.</p><p><strong>Method: </strong>Consenting NICU healthcare providers across eight NICUs in Karnataka State participated in the study. Stress and psychological distress were examined using the Tool to Assess and Classify Work-Related Stress (TAWS-16) and the Kessler Psychological Distress (K10).</p><p><strong>Results: </strong>Among 171 participants, the prevalence of work stress was 32.7%, with 19.3% reporting stress symptoms and 38.6% experiencing psychological distress. Key stressors included meeting deadlines (80.7%), performing multiple roles (69.6%), long hours of work (60.3%), and unsatisfactory remuneration (61.4%). NICU mortality (OR = 1.13, 95% CI 1.025-1.26, <i>P</i> = 0.019) and being a trainee (OR = 2.33, 95% CI 1.08-5.02, <i>P</i> = 0.03) posed a higher risk for occupational stress.</p><p><strong>Conclusions: </strong>Nearly one-third of healthcare professionals in NICU reported stress and psychological distress at the workplace. Study findings highlight the need to lower NICU mortality and enhance organizational support for trainee staff.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"167-171"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Factors of Anxiety, Depression, and Burnout Among App-Based Food Delivery Riders in Tamil Nadu: A Cross-Sectional Study.","authors":"Janmejaya Samal, Narrain Shree Sathiyarajeswaran, R Radhakrishnan, A Abdul Gaffoor, M Krupalakshme, M Benson Thomas","doi":"10.4103/ijoem.ijoem_282_24","DOIUrl":"10.4103/ijoem.ijoem_282_24","url":null,"abstract":"<p><strong>Introduction: </strong>The rapid growth in the food delivery industry, driven by changing consumer habits and technology, has created job opportunities for gig riders, including food delivery riders.</p><p><strong>Objectives: </strong>The objective of this study was to estimate the prevalence of anxiety, depression, and burnout and assess the associated factors among app-based food delivery riders in Tamil Nadu.</p><p><strong>Methods: </strong>A cross-sectional study was conducted among 425 app-based male food delivery riders in Tamil Nadu. The data were collected from June to July 2023 using the Generalized Anxiety Disorder Screener (GAD-7), Patient Health Questionnaire-2 (PHQ-2), and Oldenburg Inventory Burnout (OLBI) Scale to estimate the prevalence of anxiety, depression, and burnout, respectively.</p><p><strong>Results: </strong>The prevalence of low/medium and high burnout was 89.2% and 10.8%, respectively; the prevalence of moderate and moderate-severe/severe anxiety was 23.7% and 12.5%, respectively; and the prevalence of moderate and moderate-severe/severe depression was 26.8% and 16.2%, respectively. The multivariate logistic regression showed that monthly income (AOR 2.57) and severe depression (AOR 2.87) are significantly associated with burnout. Monthly income (AOR 3.18), burnout (AOR 2.52), and severe depression (AOR 7.35) are significantly associated with anxiety. Similarly, dehydration (AOR 3.16), place of work (AOR 3.18), burnout (AOR 2.57), and severe anxiety (AOR 6.87) are significantly associated with depression.</p><p><strong>Conclusions: </strong>The study underscores the urgent need for industry-wide interventions and support strategies to address the mental well-being of food delivery riders.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 2","pages":"96-101"},"PeriodicalIF":0.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12318562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144785583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Occupational and Non-Occupational Exposure to Chromium Induces Oxidative Stress and DNA Damage in the Population Near Kanpur Tanneries.","authors":"Pragya Verma, Phool G Yadav, Kumari Pragati, Ramji Dubey","doi":"10.4103/ijoem.ijoem_43_24","DOIUrl":"https://doi.org/10.4103/ijoem.ijoem_43_24","url":null,"abstract":"<p><strong>Background: </strong>The chrome tanning method is widely used in the Indian tannery industry. Workers from these tanneries are directly exposed to Cr compounds due to inadequate safety measures and knowledge.</p><p><strong>Objective: </strong>This study aimed to examine oxidative stress and DNA damage in tannery workers in Kanpur exposed to Cr both in the workplace and outside of it in terms of health.</p><p><strong>Methods: </strong>Blood samples were collected from the people of Jajmau, Kanpur, India. The study population was divided into three distinct categories. Group I comprised 100 individuals occupationally exposed to chromium (Cr) in tannery industries. Group II included 100 individuals who resided near tannery industries but were not occupationally exposed to Cr. Finally, Group III contained 100 healthy individuals who had never been exposed to Cr. Inductively coupled plasma‒mass spectrometry (ICP-MS) was used to measure Cr in all blood samples. Malondialdehyde (MDA), reduced glutathione (GSH), and superoxide dismutase (SOD) concentrations were used to quantify oxidative stress. A comet assay was used to determine the extent of DNA damage, and the lengths of comet tails in both the exposed and control groups were measured.</p><p><strong>Results: </strong>Cr, MDA, SOD, and DNA damage levels were significantly greater in the exposed groups than in the control groups (<i>P</i> < 0.001), whereas GSH levels were significantly lower (<i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>This study's findings indicate that timely identification of the detrimental impacts of Cr on individuals employed in tanneries is highly important for mitigating health risks and minimizing exposure.</p>","PeriodicalId":43585,"journal":{"name":"Indian Journal of Occupational and Environmental Medicine","volume":"29 1","pages":"25-31"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12017675/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}