Dental Hypotheses最新文献

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Efficacy of Application of Periodontal Ligament Stem Cells in Bone Regeneration: A Systematic Review of Animal Studies 牙周韧带干细胞在骨再生中的应用:动物研究的系统综述
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_136_22
Pardis Aghandeh, Farnaz Kouhestani, Fatemeh Isamorad, S. Akbari, Behrad Tanbakuchi, S. Motamedian
{"title":"Efficacy of Application of Periodontal Ligament Stem Cells in Bone Regeneration: A Systematic Review of Animal Studies","authors":"Pardis Aghandeh, Farnaz Kouhestani, Fatemeh Isamorad, S. Akbari, Behrad Tanbakuchi, S. Motamedian","doi":"10.4103/denthyp.denthyp_136_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_136_22","url":null,"abstract":"Introduction: We aimed to systematically review the animal studies that have investigated the efficacy of periodontal ligament stem cells (PDLSCs) in bone regeneration. Methods: Web of science, Scopus, PubMed, Embase, Cochrane Library, and ProQuest were searched to September 2022 for animal studies investigating bone regeneration using PDLSCs. Results: Twenty studies were included. Calvaria and alveolar defects were treated with stem cells. The cells were mainly carried with hydrogel, hydroxyapatite, and collagen scaffolds. PDLSCs promoted osteogenesis compared with cell-free scaffolds, except in one study where biphasic calcium phosphate block scaffolds alone or with Bone morphogenic protein 2 had superior outcomes in calvaria defects. Controversial results were reported when comparing the osteogenic potential of PDLSCs and bone marrow stem cells. Two studies reported higher potential in BMSCs, and two others reported higher bone formation and more bone quality in PDLSCs. Conclusion: With the limitations of this study, PDLSCs might have promising potential to accelerate bone regeneration in artificial defects; however, due to high heterogeneity in the outcomes of the present studies, before moving forward to human experiments, further preclinical in vivo studies are needed.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"111 - 116"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48954439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Lessons Learned from the COVID-19 Pandemic in Implant Dentistry Settings 从2019冠状病毒病大流行中吸取的经验教训
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_119_22
Mohammed Hussein Hussein Alsharbaty, Moein Shirazi, N. Mohammed, Fatemeh Akbari
{"title":"Lessons Learned from the COVID-19 Pandemic in Implant Dentistry Settings","authors":"Mohammed Hussein Hussein Alsharbaty, Moein Shirazi, N. Mohammed, Fatemeh Akbari","doi":"10.4103/denthyp.denthyp_119_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_119_22","url":null,"abstract":"In 2019, Wuhan city of China announced the epidemic of COVID-19 as a public health disaster which has been recognized as an uncommon type of single stranded RNA virus belonging to Coronaviridae family and then quickly spread all over the world. Clinically symptomatic patients are identified as the primary source of COVID-19 transmission. Most of dental procedures require the use of high-speed handpieces which leads to aerosol generation. Implant dentistry is the field of dentistry which deals with prosthetic rehabilitation with minimal aerosol generation ensuring an aseptic surgical environment. There are several decisive recommendations regarding COVID-19 precautions that should be appreciated in implant dentistry. Sharp drills in slow speed drilling machines are preferred during surgery. Regular irrigation with high volume suction is greatly encouraged. Osteotomes are encouraged over ultrasonic devices to minimize the generation of aerosols during surgical procedures. Immediate implants placement is more preferred as the number of visits to the dentists is reduced. Impression techniques should be shifted to the digital approach instead of conventional methods. Full mouth rehabilitation cases requiring complex procedures should be accomplished restrictedly.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"158 - 161"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44651179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Could Mouth Breathing Lead to Adenoid Hypertrophy? 口腔呼吸会导致腺样体肥大吗?
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_132_22
Xiao-Kai Ma, Qingyu Wang
{"title":"Could Mouth Breathing Lead to Adenoid Hypertrophy?","authors":"Xiao-Kai Ma, Qingyu Wang","doi":"10.4103/denthyp.denthyp_132_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_132_22","url":null,"abstract":"Introduction: Adenoid hypertrophy (AH), an immune response of the body against infections, is common in children and has adverse effects on their physical and mental health. The hypothesis: We hypothesized that mouth breathing (MB) may induce AH, and that they interact with each other. Evaluation of The Hypothesis: AH may cause upper airway obstruction, which can induce the patient to switch from nasal breathing to mouth breathing (MB). However, MB does not involve the processes of warming, humidifying, and cleaning the inhaled air, which leads to changes in the oral environment and increases the risk of inflammation of the upper respiratory tract. This study discussed the relationship between MB and AH. The importance of this hypothesis is that attention should be paid to the status of MB or AH while treating them in order to block the interaction and thus improve the efficiency of treatment.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"154 - 157"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44342418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the Relationship between Expression of p63 with Different Clinical Types of Oral Lichen Planus: A Retrospective Immunohistochemistry Study p63表达与口腔扁平苔藓不同临床类型的关系:回顾性免疫组织化学研究
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_83_22
M. Abdulhussain, Karrar N. Shareef, M. Zubidi
{"title":"Assessment of the Relationship between Expression of p63 with Different Clinical Types of Oral Lichen Planus: A Retrospective Immunohistochemistry Study","authors":"M. Abdulhussain, Karrar N. Shareef, M. Zubidi","doi":"10.4103/denthyp.denthyp_83_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_83_22","url":null,"abstract":"Introduction: We aimed to assess the expression of p63 among different clinical types of oral lichen planus. Methods: The current study includes 44 oral lichen planus cases from the oral pathology laboratory, oral diagnostic department, Baghdad University. P63-PRM114P used as primary monoclonal antibodies. The intensity of immunohistochemistry activity was calculated utilizing the following criteria: weak intensity: one positive cell, moderate intensity: two positive cells, and strong intensity: three or more positive cells (magnification 20×). Results: The mean age of participants was 52.82 ± 12. No significant relationship found between gender and expression of p63 (P = 0.65). The p63 expressed in all clinical types of oral lichen planus (OLP). Yet, expression of p63 was not significantly related to the clinical type of OLP (P = 0.98). Conclusion: We could not found relationship between expression of p63 among different clinical types of oral lichen planus. With respect to the limited sample size of this study, some larger scale studies among different populations are need to reach to a definitive conclusion regarding relationship between expression of p63 among different clinical types of oral lichen planus.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"132 - 135"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46101919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Assessment of the Correlation between Gender and Third Molar Surgery Duration 性别与第三磨牙手术时间的相关性评估
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_101_22
E. Abdulkareem, Mohammed M. Ali, Sabah Abdul Rasool Hammoodi, Riyam Talib
{"title":"Assessment of the Correlation between Gender and Third Molar Surgery Duration","authors":"E. Abdulkareem, Mohammed M. Ali, Sabah Abdul Rasool Hammoodi, Riyam Talib","doi":"10.4103/denthyp.denthyp_101_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_101_22","url":null,"abstract":"Introduction: This study aimed to determine whether there was a difference in the duration it required to extract impacted molars based on the sex of the patient. Methods: In this study, 108 patients with impacted mandibular third molars who attended the Tikrit Dental College (50% of them were men, aged 18–30) were included. The impactions were classified using the Winter’s method. The surgery duration was defined as the time between incision and final suturing. Data were analyzed by point-biserial correlation and chi-squared test using R software. Results: The frequencies of different types of impactions were similar between males and females (P ˃ 0.05). The most common type of impaction was mesioangular, followed by distoangular, straight, and horizontal. Negatively very weak correlation found between gender and third molar surgery duration (r = −0.15, P = 0.11, 95% CI −0.037–0.331). Conclusion: No significant correlation among gender and duration of surgery was found. To validate the findings of this study, further research with a larger sample size is needed.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"139 - 141"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46733989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Evaluation of Marginal Microleakage Between Bulk-Fill, Preheated Bulk-Fill, and Bulk-Fill Flowable Composite Resins Above and Below Cemento-Enamel Junction Using Micro-Computed Tomography: An In Vitro Study 使用微型计算机断层扫描技术对水泥-搪瓷连接上方和下方的散装填充、预热散装填充和散装填充可流动复合树脂的边际微渗漏进行比较评估:一项体外研究
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_104_22
Nidhal Dilian, A. Kadhim
{"title":"Comparative Evaluation of Marginal Microleakage Between Bulk-Fill, Preheated Bulk-Fill, and Bulk-Fill Flowable Composite Resins Above and Below Cemento-Enamel Junction Using Micro-Computed Tomography: An In Vitro Study","authors":"Nidhal Dilian, A. Kadhim","doi":"10.4103/denthyp.denthyp_104_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_104_22","url":null,"abstract":"Objective: The aim of this study was to compare the marginal microleakage between bulk-fill, preheated bulk-fill, and bulk-fill flowable composite resins above and below cemento-enamel junction (CEJ) using micro-computed tomography. Methods: Sixty freshly extracted premolar teeth were prepared with a slot shaped cavities of a total of 120 Class II: 3 mm (bucco-lingual), 2 mm (mesio-distal) with mesial gingival margin located 1 mm coronal to CEJ, and distal gingival margin located 1 mm apical to the CEJ. The samples were randomly divided into two main groups according to the restorative material (Tetric EvoCeram and 3M Filtek), and each group was further sub-divided into three subgroups according to the consistency (bulk fill, preheated bulk fill, and bulk fill flowable). The specimens were thermocycled (500 cycles, 5–55 °C, 30 seconds dwell time) and immersed in a 50% ammonical silver nitrate for 24 hours. Microleakage was evaluated using micro-CT. Data analyzed via three-way ANOVA and random forest model (a machine learning algorithm). Results: There was no statistically significant three-way interaction between type of composite, location of gingival margin related to CEJ, and filling technique (P = 0.103). However, the random forest model (a machine learning algorithm) showed type of composite is the most influential factor. Conclusion: Within the limitations of this study, considering the importance of the type of composite, the teeth restored with preheated bulk fill composite showed decrease in microleakage in comparison with bulk fill flowable composite.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"128 - 131"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47412971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Comparison of Shear Bond Strength of Three Luting Materials Used in Band and Loop Space Maintainer Cementation: An In Vitro Study 三种Luting材料用于带和环空间保持器胶结的剪切强度比较:体外研究
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_114_22
Sara Zaidan, Reem A. Rafeeq
{"title":"Comparison of Shear Bond Strength of Three Luting Materials Used in Band and Loop Space Maintainer Cementation: An In Vitro Study","authors":"Sara Zaidan, Reem A. Rafeeq","doi":"10.4103/denthyp.denthyp_114_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_114_22","url":null,"abstract":"Introduction: Aim of this study is to compare shear bond strength of different luting materials used in fixed space maintainer cementation. Methods: Thirty intact extracted human third molars randomly divided into three equal groups: group A: RelyX luting 2 (resin modified glass ionomer); group B: TOTALCEM (self-adhesive resin cement/ dual cure); group C: Transbond plus (compomer). After bonding procedures, the samples were kept in distilled water at 37°C for 24 hours prior to the shear bond strength test. Data were analyzed blindly by one-way ANOVA test and the Tukey post hoc test using R software. Results: There were statistically significant differences between the three luting materials (P  <  0.001). Conclusion: TOTALCEM showed significantly higher shear bond strength than RelyX luting 2 and Transbond plus. With respect to limitations of in vitro studies, long-term clinical studies required.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"136 - 138"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44578709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Efficacy of Three Commercially Available Fluoride Releasing Varnishes in Remineralization of Artificial White Spot Lesions Evaluated by Laser Fluorescence: An In Vitro Study 三种市售释氟清漆对人工白斑损伤再矿化作用的激光荧光评价:体外研究
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_79_22
Abeer Abdul-Kareem Hussain, Reem A. Rafeeq
{"title":"Efficacy of Three Commercially Available Fluoride Releasing Varnishes in Remineralization of Artificial White Spot Lesions Evaluated by Laser Fluorescence: An In Vitro Study","authors":"Abeer Abdul-Kareem Hussain, Reem A. Rafeeq","doi":"10.4103/denthyp.denthyp_79_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_79_22","url":null,"abstract":"Introduction This study aimed to assess the remineralization of shallow and deep artificial white spot lesion (WSL) by the application of three fluoride releasing varnishes. Methods Sixty-four extracted premolars were subjected to acid attack inducing two depths of WSLs. Using a DIAGNOdent pen, teeth were divided into two groups according to the WSL depth: shallow enamel (SE) and deep enamel (DE). Then each was subdivided into four intervention groups of eight teeth each: MI varnish, Clinpro White varnish, Clinpro XT, or control (artificial saliva). Laser fluorescence were measured via DIAGNOdent pen at baseline, demineralization stage, 24 h, 4 weeks, and 8 weeks after intervention. Results For each lesion depth, there were statistically significant differences among the agents after intervention (P < 0.01) and among time intervals for each group (P < 0.01). Conclusion MI varnish is more effective than Clinpro White varnish or Clinpro XT in remineralizing two depths of WSLs at different time points.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"117 - 120"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45026713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Shade Matching of OMNICHROMA Analyzed by Four Digital and Visual Shade Selection Techniques: An In Vitro Study 用四种数字和视觉阴影选择技术分析OMNICHROMA的阴影匹配:体外研究
IF 0.5
Dental Hypotheses Pub Date : 2022-10-01 DOI: 10.4103/denthyp.denthyp_88_22
A. Al-Hadithi, M. Gholam
{"title":"Shade Matching of OMNICHROMA Analyzed by Four Digital and Visual Shade Selection Techniques: An In Vitro Study","authors":"A. Al-Hadithi, M. Gholam","doi":"10.4103/denthyp.denthyp_88_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_88_22","url":null,"abstract":"Introduction: To evaluate the shade matching of teeth restored with OMNICHROMA using four different teeth shade-selection techniques. Methods: Thirty sound upper first premolar teeth were used. Shade was taken by the VITA Linearguide 3D-MASTER, the VITA Easyshade V, digital photography, and the TRIOS 3 intraoral scanner for the cervical area. Subsequently, a Class V cavity was prepared and filled with an OMNICHROMA filling, and another reading for the shade was taken. Results: Value of ΔE in all groups were significantly higher than the clinically acceptable value (ΔE: 3.7) (P < 0.001). One-way ANOVA measurements showed statistically significant differences among the groups (P < 0.001). Conclusion: OMNICHROMA composite showed some degree of mismatch with the surrounding tooth structure. This in vitro model could not simulate complex oral situation and more clinical studies are necessary.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"124 - 127"},"PeriodicalIF":0.5,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43651430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Does the Position of the Third Molar Have an Influence on the Location of Mandibular Fractures? 第三磨牙的位置对下颌骨骨折的位置有影响吗?
IF 0.5
Dental Hypotheses Pub Date : 2022-07-01 DOI: 10.4103/denthyp.denthyp_64_22
Julio Cesar Moretti, Rubens Camino Junior, Celso Palmieri Jr, J. Luz
{"title":"Does the Position of the Third Molar Have an Influence on the Location of Mandibular Fractures?","authors":"Julio Cesar Moretti, Rubens Camino Junior, Celso Palmieri Jr, J. Luz","doi":"10.4103/denthyp.denthyp_64_22","DOIUrl":"https://doi.org/10.4103/denthyp.denthyp_64_22","url":null,"abstract":"Introduction: This study evaluated the possible influence of the lower third molar and its position on the location of fractures in all mandibular regions. Methods: Computed tomography scans of patients with mandibular fractures in any region seen between August 2018 and July 2019 were evaluated. The presence and classification of third molars according to their vertical and horizontal positions and angulations were analyzed. Data were analyzed using the chi-square test, tree algorithm, and random forest model. Results: A total of 49 patients with mandibular fractures were seen and 40 patients (80% men), with a mean age of 33.4 years, were included. There was no correlation between fracture location and the vertical (P = 0.93) and horizontal (P = 0.76) Pell and Gregory classifications. There was a statistically significant relationship between fracture location and the Winter angulation classification (P = 0.01). Conclusion: Relative to the possible influence of lower third molars and their position on the location of mandibular fractures in all mandibular regions, only the angulation of the third molar had an influence. There was no correlation between the presence and the classifications of third molar impaction.","PeriodicalId":43354,"journal":{"name":"Dental Hypotheses","volume":"13 1","pages":"86 - 89"},"PeriodicalIF":0.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49325697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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