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BMI in Evaluating Obesity of Contemporary College Students BMI在评价当代大学生肥胖中的作用
Medical Research Frontiers Pub Date : 2023-06-15 DOI: 10.57237/j.mrf.2023.02.006
Yu-xiang Hong, Wang Hui, Chong-lin Zhang
{"title":"BMI in Evaluating Obesity of Contemporary College Students","authors":"Yu-xiang Hong, Wang Hui, Chong-lin Zhang","doi":"10.57237/j.mrf.2023.02.006","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.02.006","url":null,"abstract":": Background: Changes in lifestyle and reduction in physical activity have led to a continuous increase in the number of obese people in my country, but the criteria for determining obesity are different. Body mass index (BMI) is the most commonly used indicator for obesity research. Objective: To evaluate the authenticity, reliability and profitability of the obesity determination standard of body mass index (BMI) of college students, using the body fat rate obesity determination standard proposed by the National Center for Disease Control and Prevention as the gold standard, and to discuss BMI as a diagnostic performance and suitable cut-off value for excess body fat percentage. Methods: 1208 college students (557 males and 651 females) were tested, the height and weight were measured to calculate BMI, and the electrical impedance method was used to measure the percentage of body fat (BF%) and the ROC curve cutoff value to construct the BMI obesity diagnosis. standard. Results: The authenticity evaluation of BMI as an obesity screening","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"36 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125728782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research Progress of Protective Effect of Drug Therapy on Fertility in Female Patients with Lymphoma 药物治疗对女性淋巴瘤患者生育保护作用的研究进展
Medical Research Frontiers Pub Date : 2023-06-15 DOI: 10.57237/j.mrf.2023.02.004
Shuqing Wu
{"title":"Research Progress of Protective Effect of Drug Therapy on Fertility in Female Patients with Lymphoma","authors":"Shuqing Wu","doi":"10.57237/j.mrf.2023.02.004","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.02.004","url":null,"abstract":": Lymphoma is a common hematological malignancy in young population. During the treatment of lymphoma, the gonadal damage caused by chemotherapy cannot be ignored for the reverse impact on the reproductive function of the patients during survivorship. As the survival period of lymphoma patients has increasingly extended, fertility preservation is now a hot topic. Fertility preservation methods for female patients currently include embryo cryopreservation, oocyte cryopreservation, ovarian tissue cryopreservation, pharmacological protection therapy, etc. Among them, pharmacological protection therapy has a wide range of applications thanks to its cheapness and easy implementation. It is based on the use of gonadal function-related hormone analogues, including gonadotropin-releasing hormone agonists and antagonists, with the effort to slow down the progression of premature ovarian failure and thus preserve the long-term reproductive potential. Although most studies suggest that it has a clear reproductive protective effect, there are still some research results that hold different opinions, especially for high-risk patients requiring","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128316026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Network Pharmacology to Investigate the Mechanism of Ginseng and Atractylodis Macrocephalae to Prevent Diarrhea 网络药理学研究人参与苍术预防腹泻的作用机制
Medical Research Frontiers Pub Date : 2023-06-15 DOI: 10.57237/j.mrf.2023.03.001
Zeyuan Zhao, Han Yixin, Lifeng Wang, Yuchen Zhu, Zheng Fufan, Liu Ying, Jiahui Wang
{"title":"Network Pharmacology to Investigate the Mechanism of Ginseng and Atractylodis Macrocephalae to Prevent Diarrhea","authors":"Zeyuan Zhao, Han Yixin, Lifeng Wang, Yuchen Zhu, Zheng Fufan, Liu Ying, Jiahui Wang","doi":"10.57237/j.mrf.2023.03.001","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.03.001","url":null,"abstract":": To investigate the molecular mechanism of Ginseng and Atractylodes macrocephala in the prevention and treatment of diarrhea based on network pharmacology and molecular docking. The active ingredients and the related targets of Ginseng and Atractylodes were searched and collected through TCMSP database, PubChem","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130490847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Research on Pattern Classification of Autism Spectrum Disorder Related to the Diagnosis of Attention Deficit Hyperactivity Disorder 与注意缺陷多动障碍诊断相关的自闭症谱系障碍模式分类研究
Medical Research Frontiers Pub Date : 2023-05-25 DOI: 10.57237/j.mrf.2023.02.003
Yue Wang, Yun Li, Yao Wang, Chunyan Li, Linyan Fu, X. Ke
{"title":"Research on Pattern Classification of Autism Spectrum Disorder Related to the Diagnosis of Attention Deficit Hyperactivity Disorder","authors":"Yue Wang, Yun Li, Yao Wang, Chunyan Li, Linyan Fu, X. Ke","doi":"10.57237/j.mrf.2023.02.003","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.02.003","url":null,"abstract":"","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123843130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Harm of Methamphetamine Abuse and Studies of Drug Interventions 甲基苯丙胺滥用的危害及药物干预研究
Medical Research Frontiers Pub Date : 2023-04-25 DOI: 10.57237/j.mrf.2023.02.002
Yuyang Li, Zhenghui Chen, Huawei Wang, Yi-Qun Kuang, Yu Zhao
{"title":"The Harm of Methamphetamine Abuse and Studies of Drug Interventions","authors":"Yuyang Li, Zhenghui Chen, Huawei Wang, Yi-Qun Kuang, Yu Zhao","doi":"10.57237/j.mrf.2023.02.002","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.02.002","url":null,"abstract":": The trend of drug abuse is widespread in the world. As a new type of drug, methamphetamine (METH) has been taken by most abusers in China. There was a long methamphetamine abusing history until now, it could cause excitatory and hallucinogenic and bring serious consequences to the abusers. The consequence of methamphetamine abuse reflected in a serious damage to the nervous system, cardiovascular system and digestive system of abusers, the abnormal nervous system made abusers have strong dependence on this drug. Therefore, drug intervention to METH","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125109001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MicroRNAs and Microcystins Induce Immune Disorders 微rna和微囊藻毒素诱导免疫紊乱
Medical Research Frontiers Pub Date : 2023-04-25 DOI: 10.57237/j.mrf.2023.02.001
Huiying Zhang, Daojun Chen
{"title":"MicroRNAs and Microcystins Induce Immune Disorders","authors":"Huiying Zhang, Daojun Chen","doi":"10.57237/j.mrf.2023.02.001","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.02.001","url":null,"abstract":": Background: Cyanobacterial blooms caused by eutrophication can not only worsen the water environment, but also produce cyanobacterial toxins when some toxic cyanobacterial blooms proliferate. Microcystin is one of the most abundant cyanobacterial toxins found in reservoirs worldwide. Among its isomer, microcystin-leucine-arginine (MC-LR) is the most abundant and most toxic variety. Various experiments have clearly shown that MC-LR has hepatotoxicity and carcinogenicity, but there are relatively few studies on its immune damage effect. Numerous studies have shown that","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"136 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123205414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Plasma Metabolomics of Liver Fibrosis Based on Bioinformatics 基于生物信息学的肝纤维化血浆代谢组学分析
Medical Research Frontiers Pub Date : 2023-04-25 DOI: 10.57237/j.mrf.2023.01.004
W. Weiru, He Jiaer, Zhixin Wen, Xuelin Duan, Jiahui Wang, Tiejian Zhao, Zheng-bing Yang
{"title":"Analysis of Plasma Metabolomics of Liver Fibrosis Based on Bioinformatics","authors":"W. Weiru, He Jiaer, Zhixin Wen, Xuelin Duan, Jiahui Wang, Tiejian Zhao, Zheng-bing Yang","doi":"10.57237/j.mrf.2023.01.004","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.01.004","url":null,"abstract":": Objective: To explore the metabolites of liver fibrosis and their interactions based on bibliometrics, and to find biomarkers and therapeutic targets for liver fibrosis. Methods: Combined Chinese and English databases were used to collect plasma metabolomics studies of liver fibrosis","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"115 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114560779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Key Issues and Novel Strategies of Stem Cell Intervention and Decellularized Scaffold Liver Tissue Engineer for End-Stage Liver Disease 干细胞干预和去细胞支架肝组织工程治疗终末期肝病的关键问题和新策略
Medical Research Frontiers Pub Date : 2023-02-16 DOI: 10.57237/j.mrf.2023.01.003
H. Deyu, Y. Min, Lin Heng, J. Lai, Zhiqing Yang, Shuai Ling, Sun Zhe, Hongyu Zhang, Zhang Leida, Zhehai Li, Lianhua Bai
{"title":"Key Issues and Novel Strategies of Stem Cell Intervention and Decellularized Scaffold Liver Tissue Engineer for End-Stage Liver Disease","authors":"H. Deyu, Y. Min, Lin Heng, J. Lai, Zhiqing Yang, Shuai Ling, Sun Zhe, Hongyu Zhang, Zhang Leida, Zhehai Li, Lianhua Bai","doi":"10.57237/j.mrf.2023.01.003","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.01.003","url":null,"abstract":": End-stage liver disease (ESLD) is ultimation of all kinds of chronic liver diseases. It is highly morbidity and mortality disease and currently no effective treatment is available. Liver transplantation (LTx) is the only way for the treatment. However, the organ source limitation interferes with clinical application of LTx. For the goal of crossing liver source shortage barrier, researches attempt to explore techniques or methods like stem cells and tissue engineering, and recent years sounds developed rapidly and bright prospects, for example, artificial liver, tissue-engineered liver and xenotransplantation etc., in particular adult stem cells like bone marrow-derived mesenchymal stem cells ( BM MSCs) and decellularized liver scaffold for large scale liver tissue engineer seems more eye-catching, and such decellularization / recellularization technology used has become the first strategy to build complex organs. We have previously discussed some points in the <Chinese Journal of Digestive Surgery > about optimizing bioscaffold materials that probably will be benificial for tissue engineer. In the present review, we would like to discuss some new developments based on research status and provide a little new thoughts, hopefully those can help people in this field in order to treat ESLD in the near future.","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"125 4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126279366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Countermeasure on Evaluation for Pathogenicity of Variation with ACMG Guidelines 应用ACMG指南评价变异致病性的对策
Medical Research Frontiers Pub Date : 2023-02-16 DOI: 10.57237/j.mrf.2023.01.002
Lian Wenchang, Jiao Shujing, Wu Song, Tang Li, Wang Huawei
{"title":"Countermeasure on Evaluation for Pathogenicity of Variation with ACMG Guidelines","authors":"Lian Wenchang, Jiao Shujing, Wu Song, Tang Li, Wang Huawei","doi":"10.57237/j.mrf.2023.01.002","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.01.002","url":null,"abstract":"","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131097239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Research Progress of Parkinson's Nonverbal Cognitive Impairment 帕金森病非语言认知障碍的研究进展
Medical Research Frontiers Pub Date : 2023-02-03 DOI: 10.57237/j.mrf.2023.01.001
Xintong Wang, Li Xi
{"title":"The Research Progress of Parkinson's Nonverbal Cognitive Impairment","authors":"Xintong Wang, Li Xi","doi":"10.57237/j.mrf.2023.01.001","DOIUrl":"https://doi.org/10.57237/j.mrf.2023.01.001","url":null,"abstract":": Parkinson's disease (PD) is one of the most disabling diseases in the middle-aged and elderly population. The cognitive decline of the middle-aged and elderly, such as verbal disorder and nonverbal disorder, has severely impacted their life. This paper systematically expounds the specific manifestations of Parkinson's patients with nonverbal cognitive impairment, like memory impairment, executive ability impairment and attention impairment, as well as revealing the neural mechanism behind them. The result shows that the decline of working memory may be related to the damage of the lateral frontal lobe and parietal cortex. PD patients' executive ability is mainly reflected in their difficulty in keeping balance, which is related to the reduction of the volume and surface area of their cerebral cortex. The attention of PD patients is easily diverted and damaged, associating with the hyperactivity of dopamine in midbrain, the decrease of medial prefrontal cortex and lateral prefrontal cortex. Based on these nonverbal cognitive impairment of PD patients, this paper also introduces the diagnosis methods of PD through the patients' hands and voice, the treatment of motor symptoms and non-motor symptoms, and the gait intervention methods, so as to improve people's understanding of PD patients.","PeriodicalId":431612,"journal":{"name":"Medical Research Frontiers","volume":"108 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133147116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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