Eurasian Journal of Pulmonology最新文献

{"title":"Management of Patients who Underwent Bronchoscopy due to Massive Hemoptysis and the İmportance of Bronchial Artery Embolization","authors":"Şerif Kurtuluş","doi":"10.14744/ejp.2022.2006","DOIUrl":"https://doi.org/10.14744/ejp.2022.2006","url":null,"abstract":": BACKGROUND AND AIM: The aim of this study is to evaluate the etiology, length of stay, treatment modality and treatment success in patients who underwent bronchoscopy due to massive hemoptysis. METHODS: The study is a cross-sectional study and was carried out with 148 patients who were transferred to our center with the complaint of massive hemoptysis between January 1, 2018 and January 1, 2021. RESULTS: The average age of the study group is 55.64±17.54. 71.6% of the patients in the study group were male. Etiological causes of patients with massive hemoptysis who underwent bronchoscopy were determined as bronchiectasis, lung cancer, tuberculosis, arterio-venous malformation and aspergilloma, respectively. The patients underwent 64.9% bronchial artery embolization (BAE), 29.7% medical treatment and 5.4% surgical treatment. The average length of stay in the intensive care unit is 4.66 days, while the length of stay in the service is 3.51 days. Relapse was seen in 9.45% of patients after BAE. The mean time to recurrence was 137.28 days. It was determined that hemoptysis recurred under 90 days in 8 cases and over 90 days in 6 cases. The success rate of BAE treatment was 90.55% and no mortal complications were observed. CONCLUSIONS: Massive hemoptysis is a life-threatening and urgent condition. Maintaining airway patency and controlling bleeding is a priority. We think that the patient should be hospitalized and followed up in the intensive care unit, contrast-enhanced thorax computed tomography and bron choscopy should be performed in the rapid diagnosis process, BAE should be preferred first in the treatment, and surgical and other treatments should be applied if necessary.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Radiological Differentiation of COVID-19 Pneumonia from Non-COVID Atypical Pneumonia","authors":"O. Turan","doi":"10.14744/ejp.2022.2008","DOIUrl":"https://doi.org/10.14744/ejp.2022.2008","url":null,"abstract":"BACKGROUND AND AIM: Atypical pneumonia involves viral and some bacterial microorganisms in etiology. As Coronavirus 2019 (COVID-19) is newly identified, the differences between coronavirus and other microorganisms causing atypical pneumonia have not been fully expressed yet. We aimed to make a clinical comparison of cases with COVID-19 and atypical pneumonia. METHODS: \"Non-COVID-19 atypical pneumonia\" (non-COVID) group included patients with both radiological and clinical confirmation of atypical pneumonia by radiologists and clinicians. Patients with a positive polymerase chain reaction test formed \"COVID-19 pneumonia\" (COVID) group. Demographics, radiological, laboratory, and clinical features were recorded retrospectively. RESULTS: A total of 177 patients (46 non-COVID and 131 COVID) were included. The mean age of the COVID group was significantly lower (p=0.040). Ground-glass density and peripheral involvement were more common in thoracic computed tomography of patients with COVID-19 (p=0.017 and p=0.019). Fever and fatigue in COVID (p<0.001 and p=0.040) and shortness of breath and gastrointestinal complaints in non-COVID group were significantly higher as presenting symptoms (p<0.001 and p=0.031). In biochemical tests, impairment in liver function tests in COVID-19 (p<0.001), impairment in kidney function tests, increased C-reactive protein (CRP) and procalcitonin (PCT) in non-COVID-19 patients were more common (p=0.003, p=0.042, and p=0.023, respectively). Serum PCT, CRP, and lymphocyte levels were significantly lower in cases with COVID-19 (p<0.001, p=0.048, and p=0.016). There was no significant difference in the prognosis of both groups (p=0.556). CONCLUSIONS: With COVID-19 pandemic, there has been an increase in atypical pneumonia cases in which viral strains play a role. Symptomatic, laboratory, and radiological differences between two groups detected in our study may help in differential diagnosis especially in winter when atypical pneumonia is more common.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"50 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Host Risk Factors in Identifying Mortality in Covid-19 Pneumonia and a New Covid-19 Mortality Index: Co-AMSCA","authors":"M. Gayaf","doi":"10.14744/ejp.2022.3002","DOIUrl":"https://doi.org/10.14744/ejp.2022.3002","url":null,"abstract":"BACKGROUND AND AIM: The purpose of the study was to examine the host risk factors related to mortality in patients hospitalized with coronavirus disease 2019 (COVID-19) pneumonia and to find a COVID-19 mortality score based on these factors. METHODS: Subjects hospitalized with COVID-19 pneumonia between March 11, 2020, and October 1, 2020, were retrospectively analyzed. The age, gender, smoking status, body mass index, blood group, severity of pneumonia, comorbidity, reverse transcriptase-polymerase chain reaction positivity, use of angiotensin-converting enzyme (ACE) inhibitors, radiological changes, and mortality rates of the patients who had proven COVID-19 pneumonia were recorded. Patients were divided into two groups according to mortality status, and the two groups were compared. The cutoff values, sensitivity and specificity values, and odds ratios were calculated to predict mortality of the new scoring system. RESULTS: A total of 422 patients (51 mortal and 371 nonmortal) participated in the study. The univariate regression analysis showed that age, male gender, smoking, comorbidity, and using ACE inhibitors were prognostic host risk factors for COVID-19-related mortality. A new scoring model with the combination of risk factors named Co-AMSCA was created in the study. The cutoff value of the system was found to be 3.5 with 88.4% sensitivity and 65.5% specificity. The mortality risk in patients with a Co-AMSCA mortality score above 3.5 points was 7.8 times higher than that in patients whose score was lower than 3.5 points. In multivariate logistic regression analysis, older age and smoking were significant risk factors for mortality. CONCLUSIONS: A mortality score was created based on host risk factors, which are easy to calculate and do not need laboratory tests and do not waste the time of the clinicians. This study showed that by using Co-AMSCA scoring model, it is possible to achieve a mortality prediction in COVID-19 patients who are hospitalized due to pneumonia.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is neck grasp a reliable screening tool for obstructive sleep apnea?","authors":"E. Sulu","doi":"10.14744/ejp.2022.1022","DOIUrl":"https://doi.org/10.14744/ejp.2022.1022","url":null,"abstract":": BACKGROUND AND AIM: Determining patients at high risk for obstructive sleep apnea (OSA) via screening tools is important as undiagnosed OSA is associated with significant morbidities. The present study is aimed to determine the usefulness of easy sleep apnea predictor (ESAP) as a diagnostic tool for OSA. METHODS: In this retrospective study, ESAP positivity was defined as the inability of the patients to wrap their necks with their own hands. The demographic, antropometric parameters, and polysomnographic values were compared between ESAP(+) and (−) groups. RESULTS: The overall 287 OSA patients (47% severe) participated in this study. Patients in the ESAP(+) group (56.4%) showed higher rates of obesity and concomitant disease and also had increased neck, waist, and hip circumference, as well as more severe OSA (p<0.05). Multivariate regression analysis demonstrated that mild and severe OSA and obesity were independent predictors for ESAP positivity. The sensitivity, specificity, positive predictive value, and negative predictive value of ESAP negativity in AHI <5 (no OSA) were 73.7%, 61%, 22.4%, and 93.8%, respectively. CONCLUSIONS: Although ESAP was not defined as a useful tool for the diagnosis of OSA, ESAP negativity can be used as a practical screening test in the primary care and outpatient clinics for excluding OSA.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of the acquisition of T790M mutation in EGFR mutant metastatic lung cancer patients who were treated with EGFR inhibitors","authors":"I. Dogan","doi":"10.14744/ejp.2022.6003","DOIUrl":"https://doi.org/10.14744/ejp.2022.6003","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"VATS cost is less than thoracotomy in operable NSCLC patients","authors":"A. Turna","doi":"10.14744/ejop_36_21","DOIUrl":"https://doi.org/10.14744/ejop_36_21","url":null,"abstract":"BACKGROUND AND AIM: Better management of financial resources provided by the government-based insurance system is one of the important challenges in the administration of hospitals. The aim of this study was to compare videothoracoscopic surgery and open thoracotomy regarding cost and hospital stay. METHODS: Eighty-eight patients who underwent video-assisted thoracoscopic surgery (VATS) or open thoracotomy for operable (stage IA–IIIA) non-small cell lung cancer were analyzed retrospectively. The general cost of hospital treatment, cost of operation, and cost of hospital stay of these patients were compared. RESULTS: A total of 48 lobectomies, 33 wedge resections, 2 segmentectomies, and 5 pneumonectomies were analyzed. Fifty-eight patients (65.9%) underwent VATS resection, and 30 patients (34.1%) had resection via open thoracotomy. There was no statistically significant difference in terms of gender, age, and pulmonary function test between the groups. The postoperative hospital stay, intensive care unit stay, was higher in patients who underwent thoracotomy compared with patients who underwent VATS (p=0.006 vs p=0.02). The total hospital cost and the cost of operation for patients operated via VATS were lower compared with the costs for patients operated via thoracotomy (p=0.026 vs p=0.014). When analyzed separately, the cost of VATS lobectomy was lower than that of lobectomy via thoracotomy; however, the difference was not statistically significant (p=0.114). CONCLUSIONS: The total hospital cost and the cost of operation via VATS are lower than the costs of thoracotomy. VATS also leads to a reduced hospital stay. VATS should be considered the gold standard in resectional surgery in patients who need lobectomy, segmentectomy, or wedge resection.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67323694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asthma and Bronchiectasis - Another Duo on the Respiratory Stage","authors":"R. Ulmeanu","doi":"10.14744/ejp.2021.9121","DOIUrl":"https://doi.org/10.14744/ejp.2021.9121","url":null,"abstract":": The overlap between asthma and bronchiectasis (BE) is a challenging topic not only for re-searchers but also for clinicians. The aim of this review was to explore the latest insight of literature focused on the association between asthma and BE from the epidemiological, clinical, functional, and therapeutical perspectives. The literature search included papers published in English in the PUBMED database in the past 10 years. From a total of 233 findings, after eliminating those nonrelated to the topic and after using additional sources, 32 relevant articles were considered. The main results of the present review highlighted that when the two conditions are associated, patients have poorer clinical outcomes, greater disease severity and exacerbation rates, increased hospitalization trend, and risk for pulmonary complications, compared with each disease alone. As future directions, the need to identify both conditions at an early stage and to offer personalized management of these different phenotypes are goals to be further addressed.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cut-off levels of D-Dimer to Predict Pulmonary Thromboembolism In COVID-19 at first admission: A Retrospective Study","authors":"Figen Öztürk Ergür","doi":"10.14744/ejp.2022.6001","DOIUrl":"https://doi.org/10.14744/ejp.2022.6001","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 most concerning variants: A review on their complications, pathogenicity, transmissibility, and immune responses","authors":"Z. Afshar","doi":"10.14744/ejop_82_21","DOIUrl":"https://doi.org/10.14744/ejop_82_21","url":null,"abstract":"Since the emergence of the coronavirus disease 2019 (COVID-19) pandemic, several different variants and strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been identified. Each of these variants has several mutations in different constituents of the original virus, such as the spike (S) glycoprotein, receptor-binding domain, N-terminal domain, and furin cleavage site region. These mutations mainly influence the virulence, infectivity, and transmission of the virus. Also, they can help the virus escape the natural- or vaccine-induced immunity in the host body. The Centers for Disease Control and Prevention categorized these variants into three major classes: variants of interest, variants of concern (VOC), and variants of high consequence. In this review, four VOCs, i.e., B.1.1.7, B.1.351, P.1, and B.1.427/B.1.429, have been presented, and their potential complications, pathogenicity, transmissibility, and capability of escaping natural- or vaccine-induced immunity are discussed. Moreover, the novel B.1.617 variant and its known characteristics are also demonstrated. In conclusion, this review can help clinicians and scientists better understand the most critical properties of the mentioned concerning variants of SARS-CoV-2 and guide them to conduct future studies on new preventive and therapeutic approaches in fighting COVID-19.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67323922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of hyperbaric oxygen, ozone, and dexpanthenol therapies in rats with acute lung injury","authors":"M. Yılmaz","doi":"10.14744/ejop_93_21","DOIUrl":"https://doi.org/10.14744/ejop_93_21","url":null,"abstract":"BACKGROUND AND AIM: Acute respiratory distress syndrome (ARDS) is a fatal disease presenting with respiratory failure. Patients with ARDS account for a considerable portion of patients staying in the intensive care unit (ICU). Therefore, advances in the treatment of these patients are of great importance. Direct or indirect injury to the lung initiates an inflammatory process. This results in impaired integrity of the alveolar-capillary membrane, pulmonary edema, and severe hypoxia. The present study compared hyperbaric oxygen (HBO), ozone, and dexpanthenol therapies administered to rats with experimentally induced ARDS, as well as the efficacy of these therapies. METHODS: Thirty-two male Wistar Albino rats were used in the study. The rats were divided into four groups. All groups were administered antibiotherapy for 5 days after administering live Escherichia coli. Group 1 (control group) rats received intraperitoneal saline. Group 2 rats were treated with HBO. Group 3 rats received an oxygen + ozone mixture. Group 4 rats received dexpanthenol. After 5 days, anesthesia was administered to all rats, blood gases were collected from the abdominal aorta, and then the rats were sacrificed. Some of the collected blood was used for cytokine assays. The right lung tissues were used for histopathological examination. The left lung tissues were used to measure enzyme levels. RESULTS: Histopathologically, there were intra-alveolar hemorrhage, edema, intensive inflammatory cell infiltration, fibrosis, collapse, type 2 alveolar cells, and macrophage accumulation in all groups. In terms of fibrosis/alveolar septal thickening, the dexpanthenol group had a significantly lower mean score than the control and HBO groups. In terms of alveolar collapse, the dexpanthenol group had a significantly lower mean score than all other groups. In terms of increased macrophage and type II alveolar cell counts, the ozone group had a significantly lower mean score than all other groups. There was no significant difference in immunohistochemical staining between the groups. In terms of superoxide dismutase levels, the dexpanthenol group had a significantly lower score than the control group. Regarding IL-10 levels, the ozone group had a significantly higher score than the control and HBO groups. The dexpanthenol group had a ORCID: Merve Yılmaz: 0000-0002-5291-0351 Pınar Mutlu: 0000-0002-7496-0026 Nihal Arzu Mirici: 0000-0002-7189-9258 Hasan Oğuz Kapıcıbaşı: 0000-0001-7275-1039 Aysel Güven Bağla: 0000-0002-1501-9324 Meltem İçkin Gülen: 0000-0002-6364-8344 Şefika Körpınar: 0000-0002-8155-3867 Havva Yasemin Çinpolat: 0000-0002-7161-2907 Department of Chest Diseases, Çanakkale Onsekiz Mart University Faculty of Medicine, Çanakkale, Turkey, 1Department of Chest Surgery, Çanakkale Onsekiz Mart University Faculty of Medicine, Çanakkale, Turkey, 2Department of Histology and Embryology, Çanakkale Onsekiz Mart University Faculty of Medicine, Çanakkale, Turkey, 3Department of Underwater a","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67323976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}