Eurasian Journal of Pulmonology最新文献

{"title":"A novel approach to pulmonary fibrosis: Stem cell therapy","authors":"Muhammad Ikrama","doi":"10.14744/ejp.2023.6007","DOIUrl":"https://doi.org/10.14744/ejp.2023.6007","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"140 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135711383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"IL-6 level but not MBL level is associated with disease severity in hospitalized patients with COVID-19","authors":"Y. Söyler","doi":"10.14744/ejp.2023.1203","DOIUrl":"https://doi.org/10.14744/ejp.2023.1203","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67326118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between thyroid transcription factor-1 positivity and epidermal growth factor receptor mutation in lung adenocarcinoma and its prognostic significance","authors":"Nuran Katgı","doi":"10.14744/ejp.2022.1204","DOIUrl":"https://doi.org/10.14744/ejp.2022.1204","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors affecting the optimal CPAP pressure level and a new prediction formula in patients with obstructive sleep apnea syndrome","authors":"Hakan Koca","doi":"10.14744/ejp.2022.6010","DOIUrl":"https://doi.org/10.14744/ejp.2022.6010","url":null,"abstract":": BACKGROUND AND AIM: Continuous positive airway pressure (CPAP) treatment is routinely recommended for patients with Obstructive Sleep Apnea Syndrome (OSAS). This study aims to investigate the factors that affect the optimal CPAP pressure level in subjects with OSAS. METHODS: The records of 100 subjects with OSAS who underwent successful manual titration for CPAP treatment were reviewed retrospectively. In addition to frequently researched variables such as age, Body Mass Index (BMI), Apnea-Hypopnea Index (AHI), and minimum oxygen saturation (SpO 2 ) level, the effects of variables such as comorbidities, Rapid Eye Movement (REM) and/or position dependence, and type of abnormal respiratory events on optimal CPAP pressure level were analyzed. The descriptive values of the obtained data were calculated as mean±SD and median [Interquartile Range (IQR)]. The statistical significance level was set at p<0.05. RESULTS: The mean age of the subjects was 49.17±10.4, and 81 of them were men. There was a positive relationship between optimal pressure and BMI, AHI, REM AHI, Non-Rapid Eye Movement Apnea-Hypopnea Index (NREM AHI), Supine AHI, and Non-supine AHI (p=0.001). A negative relationship was found between optimal pressure and minimum SpO₂ (p=0.001). Optimal pressure was higher in OSAS subjects without REM and position dependence than in those with position and REM dependence (p=0.001). Optimal pressure was significantly lower in subjects who used nasal masks than in those who used an oro-nasal mask (p=0.001). As a result, an optimal pressure prediction (Ppred) formula was developed: Ppred=9.366+0.117 BMI+0.043 AHI–0.062 Min SpO₂. While the mean optimal pressure (Popt) obtained by manual titration was 9.5±2.45 cmH₂O, the mean pressure obtained by the new formula (Ppred) was 10.3±1.89 cmH₂O (r=0.64, p<0.001). CONCLUSIONS: In summary, the present study extensively examined the factors that affect optimal CPAP pressure, and a new prediction formula was developed. Also; “Can CPAP pressure prediction formulas be used in a pandemic?” the question has also been discussed.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135710733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of insomnia in healthcare personnel after COVID-19 vaccination","authors":"İlker Yılmam","doi":"10.14744/ejp.2022.1205","DOIUrl":"https://doi.org/10.14744/ejp.2022.1205","url":null,"abstract":": BACKGROUND AND AIM: Sleep disturbances are common during Coronavirus Disease 2019 (COVID-19) infection. “Coronasomnia” is a concept used to identify sleep disturbances observed during the pandemic. Although coronasomnia has been described during and after coro-navirus infection, no data on sleep disturbances seen after vaccinations have been found. The aim of this study was to detect the prevalence of sleep disturbances observed after COVID-19 vaccinations (specifically CoronaVac). METHODS: In April 2021, healthcare personnel who had received the CoronaVac vaccine were administered questionnaires to investigate potential adverse effects of the vaccine and any sleep disturbances. RESULTS: The study included 787 individuals, of whom 506 (64.3%) were women. The mean age was 35±9.6 (19–65) years. 303 (38.5%) healthcare workers reported adverse effects after vaccination. The most common adverse effects were exhaustion, muscle pain, and headache. At least one sleep disturbance (difficulty falling asleep, frequent awakening, difficulty maintaining sleep, excessive daytime sleepiness, and need to use sleeping pills) that did not exist before vaccination but occurred afterwards was found in 86 (10.9%) participants. Women had higher insomnia scores than men (p=0.02). An important result of the study is that the insomnia scores of healthcare workers who had COVID-19 are statistically higher than those who did not (p=0.02). CONCLUSIONS: Adequate sleep is important for both protection from infection and the immune response against infection. Although coronasomnia developing after the COVID-19 variant that was identified at the beginning of the pandemic is well-defined, we believe that effects such as sleep disorders that may develop after vaccination should be monitored in the long term and in a large population.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135710742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SARS-CoV-2 infection among healthcare workers in Türkiye: A systematic review and meta-analysis","authors":"Ayşe Önal Aral","doi":"10.14744/ejp.2023.1001","DOIUrl":"https://doi.org/10.14744/ejp.2023.1001","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67326356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the novel type coronavirus on the mental health of patients","authors":"E. Sayın Gülensoy","doi":"10.14744/ejp.2022.2001","DOIUrl":"https://doi.org/10.14744/ejp.2022.2001","url":null,"abstract":"BACKGROUND AND AIM: The novel Coronavirus disease (COVID-19) emerged in China in 2019 and significantly affected the entire world. The pandemic and the restrictions led to an increase in the frequency of mental health disorders (i.e., depression and anxiety) and insomnia. The aim of the study was to evaluate mental health disorders in patients who were hospitalized because of COVID-19. The patients were evaluated 6 months after hospital discharge. METHODS: A total of 114 patients who were hospitalized at Ufuk University Hospital with the diagnosis of COVID-19 were consented to participate in the posttreatment questionnaire about demographics and a Depression, Anxiety, and Stress Scale-21. The Pittsburgh Sleep Quality Index was also given to the patients to answer. RESULTS: In our study, anxiety symptoms were detected in 34 (29.8%) individuals, stress symptoms in 9 (7.9%) individuals, and depressive symptoms in 17 (14.9%). When gender, education level, age, and marital status were evaluated, there was no significant relationship observed between depression, anxiety and stress, and sleep disorders. Only those with a history of psychiatric illness had significantly higher levels of anxiety, stress, and depression (p=0.040, p=0.047, and p=0.009, respectively). Sleep quality was poor in 88 (77.2%) patients and good (normal) in 26 (22.8%) patients. CONCLUSIONS: The results show that the sleep quality of the patients deteriorated and the symptoms of stress and anxiety increased during the COVID-19 pandemic period. Patients with a previous history of psychiatric illness were more affected.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Using Clinical Parameters to Determine the Optimal Dose of Thrombolytic Treatment in Acute Pulmonary Thromboembolism","authors":"E. Yılmazel Uçar","doi":"10.14744/ejp.2022.2007","DOIUrl":"https://doi.org/10.14744/ejp.2022.2007","url":null,"abstract":": BACKGROUND AND AIM: The objective of this study was to check if clinical parameters could help us determine the optimal dose of thrombolytic therapy for patients with acute pulmonary thromboembolism (PTE). METHODS: This was a retrospective cohort study. The data were obtained through an examination of medical records and the use of an existing clinical database. A total of 367 individuals admitted to a tertiary care hospital between 2016 and 2019 and diagnosed with PTE were evaluated. The study includes people who had massive or submassive thromboembolism that required thrombolytic therapy. There were two rt-PA dosage groups (100 mg rt-PA and 50 mg rt-PA). RESULTS: A total of 81 patients, 43 females and 38 males, were evaluated. Thirty-one of the patients were administered 100 mg rt-PA and 50 were administered 50 mg rt-PA. The mean age of patients in the 100 mg rt-PA group was 57±18 years, while it was 72±11 years in the 50 mg rt-PA group, with a statistically significant difference of p<0.001. In the malignancy 50 mg rt-PA group, the most frequent risk factors were deep vein thrombosis history 100 mg rt-PA (p=0.54 and p=0.04, respectively). Clinical findings at the time of application were similar in both groups except for systolic blood pressure. Systolic blood pressure was lower in the 50 mg rt-PA group (p=0.03). Especially the change of pulse up to the 60th minute was statistically significant in both 100 mg rt-PA and 50 mg rt-PA groups (p=0.01 and p=0.002, respectively). The change of saturation up to the 60th minute was statistically significant in the 50 mg rt-PA group (p=0.003). CONCLUSIONS: While both 100 mg and 50 mg rt-PA are applied, meaningful activity on clinical parameters is in the first 60 min. In particular, the change in pulse and saturation may be more guiding in the follow-up of treatment effectiveness. The significant improvement of clinical parameters, especially pulse and saturation, in the first hour may suggest that lower dosage rt-PA and lower administration duration may be effective in acute PTE.","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thirdhand smoke: How aware are patients?","authors":"M. O. Akbay","doi":"10.14744/ejp.2022.9002","DOIUrl":"https://doi.org/10.14744/ejp.2022.9002","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67325246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of pulmonary intensive care unit readmissions with “Stability and Workload Index For Transfer Score”","authors":"Özlem Ertan","doi":"10.14744/ejp.2022.4001","DOIUrl":"https://doi.org/10.14744/ejp.2022.4001","url":null,"abstract":"","PeriodicalId":42933,"journal":{"name":"Eurasian Journal of Pulmonology","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67324356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}