Turkish Journal of Endocrinology and Metabolism最新文献_第4页

Metabolic Age: A New Predictor for Metabolic Syndrome 代谢年龄:代谢综合征的新预测因子

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-79234

R. Mehrdad, Hamidreza Pouragha, Mohadeseh Vesal, G. Pouryaghoub, M. Naderzadeh, Z. Alemohammad

引用次数: 0

Serum Irisin Levels in Cigarette Smokers 吸烟者血清中鸢尾素水平

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-79650

B. Kırel, I. Alatas

{"title":"Serum Irisin Levels in Cigarette Smokers","authors":"B. Kırel, I. Alatas","doi":"10.25179/TJEM.2020-79650","DOIUrl":"https://doi.org/10.25179/TJEM.2020-79650","url":null,"abstract":"Objective: Irisin, a newly discovered myokine, increases thermogenesis and energy consumption, especially after exercise. It has also been reported to stimulate the transformation of white fat cells into brown fat cells. Thus, it causes weight loss and increases the sensitivity to insulin. Nicotine affects the energy metabolism of the body through several mechanisms. Cigarette smokers are widely known to show decreased weight gain and increased weight loss. Since irisin and smoking/nicotine have similar effects on energy metabolism, this study proposed to determine the serum irisin levels in smokers. Material and Methods: Thirty-one healthy smokers aged 17-24 years and 31 agematched healthy non-smokers were included in this study. Serum irisin levels were determined using ELISA. Results: The smokers had been smoking for an average of 31±19 (2-84) months and smoked an average of 13.7±0.4 (5-25) cigarettes daily. The smokers had higher height and body weight and levels of serum creatinine and triglyceride and lower levels of HDL-C than non-smokers (p<0.05). Serum irisin levels and body mass index were not different between the two groups (p>0.05). The serum irisin level was correlated only with serum creatinine level in the entire group (r=-0.26, p<0.05). The serum irisin levels were not correlated with the duration and amount of cigarette smoking, as well as levels of serum glucose, insulin, total cholesterol, triglyceride, LDL-C, HDL-C, alanine aminotransferase, free T4, and TSH in the entire group (p>0.05). Conclusion: Serum irisin level in cigarette smokers is not different to that of non-smokers. It is not related to the duration and amount of cigarette smoking. Further prospective dose and time-controlled studies are needed to investigate whether similar effects of smoking/nicotine exposure on energy metabolism are related to irisin metabolism.","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"21 1","pages":"95-101"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84673229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SRY-Positive 46-XX Testicular Disorder of Sex Development as a Rare Cause of Male Hypergonadotropic Hypogonadism: A Case Report sry阳性46-XX睾丸发育障碍是男性促性腺功能亢进症的罕见病因:1例报告

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-73399

M. Can, M. Kocabaş, İ. Çordan, H. C. Burgucu, M. Karakose, M. Kulaksızoğlu, F. Karakurt

{"title":"SRY-Positive 46-XX Testicular Disorder of Sex Development as a Rare Cause of Male Hypergonadotropic Hypogonadism: A Case Report","authors":"M. Can, M. Kocabaş, İ. Çordan, H. C. Burgucu, M. Karakose, M. Kulaksızoğlu, F. Karakurt","doi":"10.25179/TJEM.2020-73399","DOIUrl":"https://doi.org/10.25179/TJEM.2020-73399","url":null,"abstract":"Introduction Disorders of sex development (DSD) are defined as situations where chromosome structure, gonads, or anatomical structure are incompatible with each other. One of these groups of disease, 46XX testicular DSD, was first reported in 1964 (1). The prevalence of 46XX testicular DSD is estimated to be 1 in 20,000 male births (2). Although pubic hair development and penis length post-puberty are normal, these patients have infertility associated with azoospermia (3). 46XX testicular DSD is diagnosed by evaluating clinical, endocrinological, and cytogenetic test results. The most important treatment method, testosterone replacement therapy, is necessary to improve sexual characteristics and sexual desire. In this report, we aimed to document a case of 46XX testicular DSD, who presented with complaints of small testes. 46XX testicular disorder of sex development (DSD) is a rare condition characterized by sexual differentiation disorder with testicular insufficiency. Normal sex development often complicates the diagnosis of this ailment in adults. Patients are usually diagnosed incidentally during infertility research. In this article, we aimed to highlight the hormonal, molecular, and cytogenetic results of an adult male patient diagnosed with 46XX testicular DSD suffering from hypergonadotropic hypogonadism.","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"8 1","pages":"123-128"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79638448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Does Blood Glucose Regulation in Adults with Type 2 Diabetes Affect Exocrine Pancreatic Functions? 成人2型糖尿病患者血糖调节是否影响胰腺外分泌功能?

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-79839

S. Fidan, S. Kisioglu, C. K. Buruk, E. Ates, A. Coşar, H. O. Ersoz, O. Özgür

引用次数: 0

Investigation of Survivin Promoter-31 G/C Polymorphism and Survivin Levels in Acromegaly 肢端肥大症患者Survivin启动子- 31g /C多态性及Survivin水平的研究

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-77471

M. Ilhan, S. Turan, S. Turgut, Gurbet Korkmaz, N. Ozkan, Özcan İlhan Karamayaylim, E. Tasan

引用次数: 0

Evaluation of Oxidative Stress with a New Method in Differentiated Thyroid Cancer Patients on Thyrotrophin Suppression Treatment 新方法评价分化型甲状腺癌患者在促甲状腺激素抑制治疗中的氧化应激

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-78978

Abbas Ali Tam, D. Ozdemir, N. Bestepe, A. Alkan, Sevgul Fakı, O. Erel, R. Ersoy, B. Çakır

引用次数: 0

Subacute Thyroiditis Secondary to SARS-COV-2 Infection; Case Studies From Turkey SARS-COV-2继发性亚急性甲状腺炎的研究土耳其案例研究

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/tjem.2020-80585

Emine Kartal Baykan, A. Çarlıoğlu

{"title":"Subacute Thyroiditis Secondary to SARS-COV-2 Infection; Case Studies From Turkey","authors":"Emine Kartal Baykan, A. Çarlıoğlu","doi":"10.25179/tjem.2020-80585","DOIUrl":"https://doi.org/10.25179/tjem.2020-80585","url":null,"abstract":"Coronavirus disease-2019 (COVID-19) has infected more than 100 million people globally, with the pandemic still showing a quick increase in number. We reported five new cases in Turkey, where subacute thyroiditis was developed after the COVID-19 infection. Our study included three females and two male patients aged between 27 and 51 with a mean age of 39. Out of the five, four patients had a mild COVID-19 infection, and one patient had mild COVID-19 pneumonia. After 18-25 days of the disappearance of COVID-19 symptoms, subacute thyroiditis was developed in patients. Laboratory tests such as thyroid hormones and, especially, free thyroxin showed high levels while the thyroid-stimulating hormone was found to be low. The thyroid-stimulating hormone receptor antibody, anti-thyroid peroxidase, and anti-thyroglobulin antibodies were negative in all patients while the inflammatory markers were high. Thyroid ultrasound showed diffuse hypoechoic areas and diffused enlargement. There was no iodine uptake observed in the thyroid scintigraphy. The patients were diagnosed with subacute thyroiditis and prescribed oral prednisolone therapy. After a few days of starting the treatment, symptoms disappeared in all patients, and after four weeks of the onset of subacute thyroiditis symptoms, inflammatory markers turned to normal range in all patients. Therefore, physicians should consider subacute thyroiditis in the differential diagnosis of thyroid dysfunction during and after COVID-19 infection.","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"06 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72893272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Patients with Ectopic Posterior Pituitary: Report of 6 Patients 垂体后叶异位6例报告

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-78916

Hatice Özişik, B. Yurekli, Ö. Kitiş, M. Erdogan, F. Saygili

引用次数: 0

Evaluation of Influenza, Pneumococcus, Zoster, Measles, Diphtheria, and Pertussis Vaccination Rates in Patients with Type 1 and Type 2 Diabetes Mellitus; a Single-Center Experience From Turkey 1型和2型糖尿病患者流感、肺炎球菌、带状疱疹、麻疹、白喉和百日咳疫苗接种率的评价来自土耳其的单中心体验

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-79458

A. Yeşilova, M. Bilge, N. Özsoy, M. Adaş

{"title":"Evaluation of Influenza, Pneumococcus, Zoster, Measles, Diphtheria, and Pertussis Vaccination Rates in Patients with Type 1 and Type 2 Diabetes Mellitus; a Single-Center Experience From Turkey","authors":"A. Yeşilova, M. Bilge, N. Özsoy, M. Adaş","doi":"10.25179/TJEM.2020-79458","DOIUrl":"https://doi.org/10.25179/TJEM.2020-79458","url":null,"abstract":"Objective: Several vaccines have been recommended for adults with diabetes. This study aimed to determine the rates of uptake of recommended vaccines in diabetic adults and estimate their association with sociodemographic and clinical factors. Material and Methods: This was a cross-sectional study conducted on patients with either type 1 or type 2 diabetes, who had attended the outpatient clinics of internal medicine and endocrinology. The patients were inquired about their immunization status against influenza, pneumococcus, zoster, measles, pertussis, and diphtheria. Results: Among the 350 diabetic patients, 38 (10.8%) had received a vaccine against pneumococcus, 90 (26%) against seasonal influenza, and only one patient had been administered the zoster vaccine. None of the patients had been vaccinated against measles, diphtheria, and pertussis. The rate of pneumococcal vaccination (PV) increased with age (65.5±9.7 vs. 57±9.1 [OR 2.9 (95% CI=14.32.67], p=0.005), although there was no such association between influenza vaccination (IV) and age (p=0.456). The rate of PV increased with the number of routine follow-up visits per year (10/38 vs. 28/38 [OR 4 (95% CI=0.994-16.096], (p=0.039). The rates of PV and IV were significantly higher in diabetic patients with chronic pulmonary disease (21/38 vs. 14/312 [OR 52.80 (95% CI 8.4333.1], p=0.005 and 31/90 vs. 4/260 [OR 29.15 (95% CI 3.37252.28], p=0.001) respectively. The rates of IV in diabetic patients with chronic renal failure were also significantly different from those without (27/90 vs. 8/260, [OR 14.28 95% CI 1.51-133.74], p=0.013). Conclusion: We observed low rates of vaccination against influenza, pneumococcus, and zoster in patients with diabetes, which were below the targets recommended by the World Health Organization.","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"61 1","pages":"68-77"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88667391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Publication Outcomes for Oral Presentations at Congresses of Endocrinology and Metabolic Diseases of Turkey: Analysis of Twenty Years 土耳其内分泌学和代谢疾病大会口头报告的发表结果:二十年分析

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Turkish Journal of Endocrinology and Metabolism Pub Date : 2021-01-01 DOI: 10.25179/TJEM.2020-78932

Türkiye Endokrinoloji, Hastalıkları Kongresi, Sözlü Sunumlarının, Yayına Dönüşüm, Oranları Yirmi, Yılın Analizi, Emre S. Saygılı, E. Karakiliç, S. Sendur

{"title":"Publication Outcomes for Oral Presentations at Congresses of Endocrinology and Metabolic Diseases of Turkey: Analysis of Twenty Years","authors":"Türkiye Endokrinoloji, Hastalıkları Kongresi, Sözlü Sunumlarının, Yayına Dönüşüm, Oranları Yirmi, Yılın Analizi, Emre S. Saygılı, E. Karakiliç, S. Sendur","doi":"10.25179/TJEM.2020-78932","DOIUrl":"https://doi.org/10.25179/TJEM.2020-78932","url":null,"abstract":"Objective: This study aimed to analyze the publication rate for oral presentations at Congresses of Endocrinology and Metabolic Diseases of Turkey (CEMDT), their contribution to the literature, and variations over twenty years. Material and Methods: Presentations from 1997–2017 were accessed through congress booklets. PubMed and Google Scholar were used for the relevant literature search. Results: A total of 456 oral presentations were identified as having a publication conversion rate of 45.4% (207). These manuscripts were published in journals with a median impact factor (IF) of 2.79 (interquartile range (IQR): 1.77-3.58) and were found to receive a median of 9 (IQR: 3-21) citations. The publication rate in SCI/SCI-E indexed journals was 80.2% (166). The publication duration was a median of 20.6 months (IQR: 6-41 months). The multinational abstract rate was 6.8% (31), whereas 19.3% (88) of the abstracts comprised of retrospective data. The most frequent variation during the conversion to articles was a change in the order of the authors, which was observed in 65.71% (136) of cases. When the two ten-year periods from 1997-2006 and 2007-2017 are compared, the publication rate increased from 37.1% to 54.3% (p<0.01). Conclusion: This is the first study to evaluate the publication rate of the CEMDT presentations. The conversion rate for oral presentations to publication is high compared to studies from other branches of medical science in Turkey. However, it remains lower than the international congresses. There is a promising enhancement in the last ten years.","PeriodicalId":42868,"journal":{"name":"Turkish Journal of Endocrinology and Metabolism","volume":"13 1","pages":"11-20"},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90551564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0