{"title":"Role of Nanomaterials in Pharmaceutical Preparation: A Review","authors":"Sahu Mahendra Kumar, Tiwari Sandip Prasad","doi":"10.17352/2455-3492.000063","DOIUrl":"https://doi.org/10.17352/2455-3492.000063","url":null,"abstract":"Aim & objective: This study aims to explore the multifaceted applications of nanomaterials and assess their potential advantages and disadvantages. Understanding the different physicochemical properties of nanomaterials & excipients. Method: This study reviews current literature and research findings to compile a comprehensive overview of nanomaterials. Key aspects covered include synthesis methods, characterization techniques, and notable applications in different industries. The review also discusses the advantages and disadvantages associated with nanomaterials, highlighting their potential benefits and challenges. Advantages & disadvantages: Nanomaterials offer numerous advantages such as enhanced mechanical, electrical, and optical properties, which make them suitable for developing advanced technologies. However, challenges include concerns over their potential environmental and health impacts, as well as the scalability of production processes from laboratory to industrial scales. Additionally, the high cost of synthesis and regulatory uncertainties pose hurdles to widespread adoption. Conclusion: In conclusion, nanomaterials present a paradigm shift in materials science and engineering with vast potential to address pressing global challenges. Their unique properties enable innovative solutions across various sectors, promising significant advancements in healthcare, electronics, energy, and environmental sustainability. However, realizing these benefits requires continued research to mitigate risks and optimize their applications. Establishing robust regulatory frameworks and fostering interdisciplinary collaborations are essential to harnessing the full potential of nanomaterials while ensuring their safe and sustainable integration into society.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":" 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141826568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mehraliyeva Sevil, Musayeva Sevinj, Sakar Betul Ceviz, Orhan Zeyneb
{"title":"Morphological Analysis of Nanocapsules Processed based on Deer Antler Extract","authors":"Mehraliyeva Sevil, Musayeva Sevinj, Sakar Betul Ceviz, Orhan Zeyneb","doi":"10.17352/2455-3492.000062","DOIUrl":"https://doi.org/10.17352/2455-3492.000062","url":null,"abstract":"The research work is devoted to the acquisition of nanocapsules, which are one of the drug delivery systems, and their morphological analysis. In modern times, the development of new drug delivery systems from natural raw materials in the treatment and prevention of diseases of various origins is considered a priority issue of pharmacy. From this point of view, the preparation and analysis of nanocapsules based on the extract from the studied deer antlers is of great importance. As a result of the morphological analysis of nanocapsules prepared from deer antlers grown in the climatic conditions of Azerbaijan, carrageenan-coated nanocapsules have sizes 118.3-243.6 nm in SEM, 10-248 nm in TEM, and tragacanth-coated nanocapsules have sizes 33.15-224.1 nm in SEM, TEM was determined to be 15-254 nm. During numerous studies, it was determined that nanocapsules prepared with tracagant proved to be more intense and more stable. Researches were carried out in the pharmaceutical technology laboratory of Azerbaijan Medical University and AHTARC (DAYTAM) of Atatürk University of the Republic of Turkey. As a result of the conducted research, it was clear that the use of nanocapsules developed by an effective technological method from deer antlers, which has sufficient raw material reserves in Azerbaijan, is considered appropriate for future treatment of diseases in oncology, infertility, osteoarthritis, cardiovascular, and nervous system.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":"142 15","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141656161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modification of the Structure and Mechanical Properties of Cu-30%Zn alloy with Cerium and Silicon","authors":"KO Iyebeye, C. Nwambu, EE Nnuka","doi":"10.17352/2455-3492.000061","DOIUrl":"https://doi.org/10.17352/2455-3492.000061","url":null,"abstract":"This study investigates how the introduction of cerium and silicon influences the structure and mechanical characteristics of Cu-30%Zn alloy. The examined properties included tensile strength, hardness, and impact resistance. The tensile strength of the developed alloys was determined using an automated JPL tensile strength tester (Model: 130812) with a capacity of 100 kilonewtons, following the ASTM D638 standard. The impact strength was assessed by the ASTM D256 standard using a pendulum impact testing machine (Model: U1820). Additionally, hardness testing was conducted using a Brinell tester. The Brinell hardness test was performed with a portable dynamic hardness tester (Model: DHT-6) by the British Standard (BS EN ISO 6505-1:2014). Specimens were prepared by incorporating cerium and silicon into the Cu-30%Zn alloy at concentrations of 0.1wt%, 0.3wt%, 0.5wt%, 1.0wt%, 3.0wt% 5.0wt% ranging from 0.1% to 5.0%, with increments of 0.2% for micro addition and 2.0% for macro addition. Microstructural analysis was performed using an L2003A reflected light metallurgical microscope. Scanning Electron Microscopy (SEM) and energy-dispersive X-ray spectroscopy (EDX) were also utilized to characterize the cast specimens. The findings revealed a proportional increase in tensile strength, impact strength, and hardness strength with the rise in dopant concentrations up to 3.0wt% for cerium and silicon. Also, the analysis uncovered the presence of. primary α-phase, β-phase (intermetallic phases), and fine stable phase. These phase modifications contributed to the enhancement of mechanical properties. Cu-30wt%Zn enriched with 3.0% cerium and silicon demonstrated heightened tensile strength, impact strength, and hardness, making it a recommended choice for engineering applications.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":"29 21","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141660416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Scaffold-based microsphere in drug delivery system","authors":"Sharma Girja, Sharma Pk, Alam Md Aftab","doi":"10.17352/2455-3492.000058","DOIUrl":"https://doi.org/10.17352/2455-3492.000058","url":null,"abstract":"Microspheres are free-flowing powders having a synthetic and natural polymer. A targeted drug delivery system can overcome some of the problems of conventional therapy and enhance the therapeutic efficacy of the drug. This is a biodegradable and non-biodegradable efficacy of a given drug. There are various approaches to delivering a therapeutic substance to the target site in a sustained controlled release fashion. One approach is a scaffold-based microsphere for drug delivery, where the target site is very specific if modified, and the proper concentration is maintained at the site of interest without causing toxic effects. Microspheres received much attention not only for control release but also in drug targeting for example in anticancer therapy. Moreover, the joining of medications (i.e., incendiary inhibitors and additionally anti-microbial) into platforms might be utilized to forestall contamination after medical procedures and other infections for the longer term. The framework additionally can be utilized to give sufficient signs to the cells, to initiate and keep them in their coveted separation organization, and to keep up their survival and development. The present survey gives an itemized record of the requirement for the advancement of frameworks alongside the materials utilized and systems embraced to fabricate platforms for tissue designing and delay. The present review gives a detailed account of the need for the development of scaffolds along with the materials used and techniques adopted to manufacture scaffolds for tissue engineering and microspheres for drug delivery systems.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141128790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hydrogen production from sodium borohydride using Co nanoparticles","authors":"Öztekin Rukiye, Sponza Delia Teresa","doi":"10.17352/2455-3492.000055","DOIUrl":"https://doi.org/10.17352/2455-3492.000055","url":null,"abstract":"In this study, hydrogen [H2(g)] production from sodium borohydride (NaBH4) using cobalt (Co) nanoparticles (NPs) was investigated with a hydrolysis process. Optimum experimental conditions were examined at different hydrolysis times (5, 10, 20, 30, 40, 50, 60, 70, 80, and 90 min), at different hydrolysis temperatures (25, 35, 45, and 65oC), and at increasing Co NPs nanocatalyst concentrations (5, 15 and 30 mg/l) at pH = 13.0, respectively. X-ray diffraction (XRD), Field Emission Scanning Electron Microscopy (FESEM) and Transmission Electron Microscopy (TEM) analyses were performed for characterization studies. H2(g) measurements were made in gaschromatography–mass spectrometry (GC-MS). The maximum 81% H2(g) yield was observed before the hydrolysis process after 90 min, at pH = 13.0, at 25 oC. The maximum H2(g) yields were recorded as 98% after 45 min hydrolysis times at 45 oC, at a pH of 13.0. 99% H2(g) yields were found after 14 min hydrolysis times, at pH a pH of 13.0 at 65 oC. The maximum NaBH4 concentration and using Co NPs concentrations were kept constant at 300 mg/l and 1.5 mg/l, respectively.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":" 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140392046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Okeke Ifeanacho U, Nnakwo Kingsley C, Nnuka Eugene E
{"title":"Insight into the microstructure and mechanical properties of Cu-20wt%Zn-xSn ternary alloy","authors":"Okeke Ifeanacho U, Nnakwo Kingsley C, Nnuka Eugene E","doi":"10.17352/2455-3492.000056","DOIUrl":"https://doi.org/10.17352/2455-3492.000056","url":null,"abstract":"The main objective of this research is to study the grain refinement and improved trend in mechanical properties of brass (Cu-20wt%Zn) doped with tin. Tin was added in concentrations of (x: 0.1, 0.3, 0.5, 0.8, and 1wt%). The alloy samples were produced by permanent die casting and machined to the required dimensions for the structural analysis and mechanical tests. Mechanical properties studied were percentage elongation, ultimate tensile strength, and Brinell hardness using a 100KN JPL tensile strength tester (Model: 130812) and portable dynamic hardness testing machine (Model: DHT-6) respectively. The structural analysis was conducted using an optical metallurgical microscope (Model: L2003A) and scanning electron microscopy (SEM) equipped with EDS. The results of the structural analysis showed that the control specimen consisted predominantly of coarse α-phase of zinc in copper (Cu3Zn). The samples doped with tin consisted of refined α-grains with patches of the second phase (Cu8Sn5). Mechanical test results indicated that the addition of tin to alpha brass improved the ultimate tensile strength and hardness with a slight decline in percentage elongation. The values recorded for ultimate tensile strength and Brinell hardness were 322MPa and 176HB respectively.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":" 29","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140391544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Long Nguyen Viet, Nhat Hang Nguyen Thi, Cuu Ho Van
{"title":"Micro/nanosized ferrite and hexaferrite structures: The polyol processes for synthesis","authors":"Long Nguyen Viet, Nhat Hang Nguyen Thi, Cuu Ho Van","doi":"10.17352/2455-3492.000054","DOIUrl":"https://doi.org/10.17352/2455-3492.000054","url":null,"abstract":"In this research, controlled synthesis and properties of micro/nano-sized magnetic oxide powders via a polyol process are discussed. They are the original magnetic oxides that have been studied by many scholars because of their many applications. The most special forms are the diversity of FeO and Fe2O3, and the diversity of the Fe3O4 matrix which are the most important original structures with formulas to be FeO.Fe2O3 (Fe3O4) and Fe2O3 can be oxide systems of FexOy that are very common and different. On the basis of the original structures, we can synthesize the most special forms of ferrite and hexaferrite related to the four original structures, which are AB2O4-spinel-type SrFe2O4 and BaFe2O4 ferrites (M: metal elements, Sr, Ba; B: Fe), PbFe11AlO19-type MX12O19 (M: metal elements, Sr, Ba; X: Fe) SrFe12O19 and BaFe12O19 by polyol processes and technologies. We understand that elements that form original structures are incorporated into Fe3O4 to form ferrite and hexaferrite structures, typically such as SrFe12O19 by liquid-, solid- and gas-based phase chemical reactions via the polyol processes and heat treatment processes. In the future, we suggest that the original oxide structure and formula of natural minerals can be used as the new magnetic structures and compounds.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":"71 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139285022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Marine fouling: Factors affecting biofouling and future perspectives","authors":"Vourna Polyxeni, Xafakis Sotirios, Stefanakis Nikos, Vourna Paraskevi, Papadopoulos Nikolaos D","doi":"10.17352/2455-3492.000052","DOIUrl":"https://doi.org/10.17352/2455-3492.000052","url":null,"abstract":"Biofouling of the hulls of ships and vessels, caused by the colonization of animals and plants, is an ongoing problem for the shipping industry. Biofouling evokes surface roughness, which results in higher fuel consumption, emissions, and operating costs. Mitigation of biofouling is a complex problem and the effectiveness of any given approach depends on many factors. Compared to complex anti-fouling technologies, the use of anti-fouling coatings presents the most viable solution, both in terms of cost and efficiency. Nevertheless, due to the modest performance of most modern antifouling hull coatings, frequent maintenance, and dry-docking intervals are still required. In addition, application costs are often not negligible. New antifouling technologies, such as low-drag antifouling paints with broad spectrum activity are urgently required in order to promote smoothness of the surface as well as provide adequate protection against biofilm formation. The development of innovative nanocomposite coating structures which combine low-drag film surfaces with antimicrobial components within water-soluble matrices may be a drastic solution to the above problem. Moreover, applying such structures directly on the hulls of ships and marine vessels without the use of primers is a long-awaited possibility, which could have a tremendous impact on reducing application costs.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127046388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tandem architectures for artificial thylakoid membranes","authors":"Redel Engelbert","doi":"10.17352/2455-3492.000051","DOIUrl":"https://doi.org/10.17352/2455-3492.000051","url":null,"abstract":"In this concept paper, new layered materials, such as multilayer hybrid systems, are described. These materials can be implemented into novel biomimetic devices, which can act as artificial photosystems or as “artificial thylakoid membranes” e.g. for the splitting of water. The architecture can be based on active nanoparticles or small catalytic clusters which can be synthesized from robust, inexpensive, and abundant material precursors. These multi-layered architectures can act as “artificial thylakoid membranes”, which can mimic the photosynthetic apparatus on the nanoscale. The development of “artificial thylakoid membranes” and tandem devices promises a strong impact and benefits for the field of artificial photosynthesis and the development of artificial leaves.","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134102480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fullerene and nanotube models in Bolyai - Lobachevsky hyperbolic geometry H3 on the 200th anniversary of its discovery","authors":"Molnár Emil, Szirmai Jenő","doi":"10.17352/2455-3492.000050","DOIUrl":"https://doi.org/10.17352/2455-3492.000050","url":null,"abstract":"The Archimedean solid (5, 6, 6), where regular pentagon, hexagon and hexagon surround each vertex, so altogether 60 vertices (with carbon atoms for C60 fullerene). 12 pentagons and 20 hexagons bound this football polyhedron,","PeriodicalId":428573,"journal":{"name":"International Journal of Nanomaterials, Nanotechnology and Nanomedicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122695593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}