Revista de Osteoporosis y Metabolismo Mineral最新文献

{"title":"Asociación de parámetros bioquímicos del metabolismo óseo con progresión y/o desarrollo de nuevas calcificaciones aórticas","authors":"C. G. Alonso, M. R. García, N. A. Llano, C. G. Gil-Albert, C. Antequera, S. F. Villabrille, J. R. Carrio, AA Díaz Sottolano, J. F. Martín, J. C. Andía, M. N. Díaz","doi":"10.4321/S1889-836X2021000100003","DOIUrl":"https://doi.org/10.4321/S1889-836X2021000100003","url":null,"abstract":"Correspondencia: Manuel Naves Díaz (mnaves.huca@gmail.com) Gómez Alonso C1, Rodríguez García M2, Avello Llano N3, García Gil-Albert C3, Palomo Antequera C4, Fernández Villabrille S1, Rodríguez Carrio J5, Díaz Sottolano AA6, Fernández Martín JL1, Cannata Andía JB1, Naves Díaz M1 1 Unidad de Gestión Clínica de Metabolismo Óseo. Hospital Universitario Central de Asturias. Universidad de Oviedo. Instituto de Investigación Sanitaria del Principado de Asturias (ISPA). Red de Investigación Renal del Instituto de Salud Carlos III (REDinREN del ISCIII). Oviedo (España) 2 Area Gestión Clínica de Nefrología. Hospital Universitario Central de Asturias. Universidad de Oviedo, ISPA. REDinREN del ISCIII. Oviedo (España) 3 Laboratorio de Medicina. Hospital Universitario Central de Asturias. Oviedo (España) 4 Unidad de Gestión Clínica de Medicina Interna. Hospital Universitario Central de Asturias. Universidad de Oviedo, ISPA. Oviedo (España) 5 Investigación Básica y Traslacional en Enfermedades inflamatorias Crónicas. Universidad de Oviedo, ISPA. Oviedo (España) 6 Hospital de Cabueñes, ISPA. Gijón (España)","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":"13 1","pages":"10-16"},"PeriodicalIF":0.6,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48151273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perfil asistencial del paciente con osteoporosis tributario de visita de telemedicina en la era post-COVID-19","authors":"J. M. Cancio, A. Capdevila-Reniu, T. Casanova, L. Cuadra, A. Ivanov, A. Llopis, J. M. Santiago, E. Sopeña","doi":"10.4321/S1889-836X2021000100008","DOIUrl":"https://doi.org/10.4321/S1889-836X2021000100008","url":null,"abstract":"Objetive: Define the profile of the candidate and non-candidate osteoporosis patient for assistance in osteoporosis teleconsultation, in the post-COVID-19 era. Proposal of a management protocol for outpatient follow-up. Methods: We have carried out a bibliographic review through a systematic search in the Pubmed.gov databases of the available evidence of articles in English and Spanish with an inclusion date until October 2020, following the recommendations of the GRADE system (Grading of Recommendations, Assessment, Development and Evaluation). Database is aimed at locating and accessing relevant information for this review in an updated way. Results: The profile of the patient candidate for teleconsultation would be of those who present a history of osteoporosis, previously diagnosed, with treatment and requiring follow-up. COVID-19 has occurred in a context in which the main causes of mortality are chronic diseases and the need to protect against transmission. Conclusions: We propose a consensus for managing this patient, with differentiated sections for the different stages of the telematic care process. This will help in clinical decision-making and also in the process of follow-up and therapeutic adherence and, therefore, in optimal use of healthcare resources.","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":"13 1","pages":"41-46"},"PeriodicalIF":0.6,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44683314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fisiopatología de la osteoporosis en las enfermedades articulares inflamatorias crónicas","authors":"S. Castañeda, M. Garcés-Puentes, M. B. Pineda","doi":"10.4321/s1889-836x2021000100006","DOIUrl":"https://doi.org/10.4321/s1889-836x2021000100006","url":null,"abstract":"Correspondencia: Santos Castañeda (scastas@gmail.com) Castañeda S1,2, Garcés-Puentes MV3, Bernad Pineda M4 1 Servicio de Reumatología. Hospital Universitario de La Princesa. Instituto de Investigación Sanitaria Princesa (IIS-Princesa). Madrid (España) 2 Cátedra UAM-Roche EPID*-Futuro (*Enfermedades Pulmonares Intersticiales Difusas). Universidad Autónoma de Madrid (UAM). Madrid (España) 3 Servicios Integrales de Gestión Médica (SIGEMED). Madrid (España) 4 Servicio de Reumatología. Hospital Universitario La Paz. Instituto de Investigación del Hospital Universitario La Paz (IdiPAZ). Madrid (España)","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48723782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implicación de la Cx43 y el cilio primario en la actividad de los osteocitos","authors":"Trabajo Fin de Grado, S. Jiménez, Arancha R. Gortazar, Elena Carrió González, J. de, Y. D. Biosistemas, Grado DE Biotecnología","doi":"10.4321/S1889-836X2020000400005","DOIUrl":"https://doi.org/10.4321/S1889-836X2020000400005","url":null,"abstract":"The bone tissue has the ability to adapt to the stimuli of the environment by altering its morphology and metabolism. The development and maintenance of this tissue are dynamic processes, regulated by the different bone cells communicated with each other through Gap Junctions (GJs). Connexin 43 (Cx43), which is the most abundant protein in GJs, has key roles in the signal transduction of bone tissue and in the response to hormonal and mechanical stimuli. Other mechanosensing elements in the osteocytes are: the primary cilium, mainly formed of microtubules and developed when the cells are in the G0 phase of the cell cycle; and the integrins, a family of glycoproteins forming heterodimers composed of two subunits (the alpha and beta chain) and located in the cell membrane. The involvement of Cx43, the primary cilium and integrins in the mouse osteocyte cell line MLO-Y4 control and deficient in Cx43 will be studied in this project. The response of this cell line to hormonal stimuli (ligand of the parathyroid hormone receptor type 1, the protein related to parathyroid hormone, PTHrP) and mechanical stimuli (by fluid flow of culture medium) will also be analyzed. In addition, the possible functional interaction between these three mechanical elements will be studied. For protein expression analyses of IFT88 (homolog of the intraflagelar transport protein 88), Cx43, P-ERK (Kinases regulated by extracellular signal phosphorylated) and P-GSK3 (Glycogen synthase kinase 3 beta phosphorylated), Western blotting was performed. The expression of the integrins was determined by PCR (Polymerase Chain Reaction) and, to characterize the possible colocalization between the primary cilium and Cx43 an immunofluorescence was performed. The results obtained show that Cx43 and the primary cilium do not collocate, and that the presence of Cx43 is not necessary for ciliogenesis. On the other hand, it was determined that fluid flow and PTHrP increase the phosphorylation of ERK and GSK3. Therefore, these stimuli regulate cell survival pathways in osteocytes. Finally, it was observed that integrin α2 increased its expression in control cells (Cx43 +/+). However, integrins α6, β1 and β3 increased in Cx43 deficient cells (Cx43 -/-), suggesting an interaction between these two protein families.","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44566667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación de la densidad mineral ósea y de los parámetros de 3D-Shaper en la hipofosfatasia congénita del adulto","authors":"C. Tornero, M. Coronado, L. Humbert, Victoria Navarro-Compán, S. Carazo, C. L. Hernández, A. Balsa, P. A. Acín","doi":"10.4321/s1889-836x2020000400004","DOIUrl":"https://doi.org/10.4321/s1889-836x2020000400004","url":null,"abstract":"Correspondencia: Carolina Tornero Marín (carolina.tornero@salud.madrid.org) Tornero C1, Coronado M2, Humbert L3, Navarro-Compán V1, García Carazo S1, Lancha Hernández C2, Balsa A1, Aguado Acín P1 1 Departamento de Reumatología. Hospital La Paz. Instituto de Investigación Sanitaria del Hospital Universitario La Paz (IdiPAZ). Madrid (España) 2 Departamento de Medicina Nuclear. Hospital La Paz. Madrid (España) 3 Galgo Medical. Barcelona (España)","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46665909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¿Las mediciones de masa ósea en fémures son simétricas?","authors":"L. D. R. Barquero","doi":"10.4321/s1889-836x2020000400001","DOIUrl":"https://doi.org/10.4321/s1889-836x2020000400001","url":null,"abstract":"","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43722422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conexina 43 y senescencia celular: nuevas estrategias terapéuticas para el tratamiento de la artrosis","authors":"P. Carpintero-Fernández, A Sánchez Temparno, A. V. Eírin, A. García-Yuste, J. Cabañas, A. Díez-Ulloa, Caeiro, Mayan","doi":"10.4321/s1889-836x2020000400008","DOIUrl":"https://doi.org/10.4321/s1889-836x2020000400008","url":null,"abstract":"Correspondencia: María D. Mayán (MA.Dolores.Mayan.Santos@sergas.es) José Ramón Caeiro (Jose.Ramon.Caeiro.Rey@sergas.es) Carpintero-Fernández P1, Sánchez Temparno A1, Varela Eírin M1,2, García-Yuste A1, Yáñez Cabanas J3, Díez-Ulloa A3, Caeiro JR3, Mayan MD1 1 Grupo de Investigación CellCOM. Instituto de Investigación Biomédica de A Coruña. A Coruña (España) 2 Instituto Europeo de Investigación para la Biología del Envejecimiento (ERIBA). Centro Médico Universitario de Groningen (UMCG). Universidad de Groningen (RUG). Groningen (Holanda) 3 Departamento de Cirugía Ortopédica y Traumatología. Complejo Hospitalario Universitario de Santiago de Compostela. Universidad de Santiago de Compostela (USC). Santiago de Compostela (España)","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47768574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparación de los valores densitométricos de la extremidad proximal del fémur en sujetos jóvenes sanos: zurdos vs. diestros","authors":"S. Naranjo-Kalinowska, P. Santana, F De la Rosa-Fernández, N. Suárez-Ramírez, M. J. G. Romero, M. Henríquez","doi":"10.4321/s1889-836x2020000400002","DOIUrl":"https://doi.org/10.4321/s1889-836x2020000400002","url":null,"abstract":"Correspondencia: Manuel Sosa Henríquez (manuel.sosa@ulpgc.es) Naranjo-Kalinowska S1, Saavedra Santana P2, De la Rosa-Fernández F1, Suárez-Ramírez N1, Gómez de Tejada Romero MJ1,3, Sosa Henríquez M1,4 1 Grupo de Investigación en Osteoporosis y Metabolismo Mineral. Instituto Universitario de Investigaciones Biomédicas y Sanitarias. Universidad de Las Palmas de Gran Canaria. Las Palmas de Gran Canaria (España) 2 Departamento de Matemáticas. Universidad de Las Palmas de Gran Canaria. Las Palmas de Gran Canaria (España) 3 Departamento de Medicina. Universidad de Sevilla. Sevilla (España) 4 Unidad Metabólica Ósea. Hospital Universitario Insular. Las Palmas de Gran Canaria (España)","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42860944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictores del riesgo de fractura en una población de mujeres postmenopáusicas mediante el procedimiento estadístico binario CART","authors":"F. Campillo-Sánchez, R. Usategui-Martín, J. Gil, Á Ruiz de Temiño, Y. González-Silva, Marta Ruiz-Mambrilla, A. Dueñas-Laita, J. L. Pérez-Castrillón","doi":"10.4321/s1889-836x2020000400003","DOIUrl":"https://doi.org/10.4321/s1889-836x2020000400003","url":null,"abstract":"Correspondencia: José Luis Pérez‐Castrillón (uvacastrv@gmail.com) Campillo-Sánchez F1, Usategui-Martin R2, Gil J3, Ruiz de Temiño A4, González-Silva Y5, Ruiz-Mambrilla M6, Dueñas-Laita A7, Pérez-Castrillón JL8 1 Servicio de Ginecología. Hospital Universitario de Guadalajara. Guadalajara (España) 2 Instituto Universitario de Oftalmobiología Aplicada (IOBA). Universidad de Valladolid. Valladolid (España) 3 Servicio de Medicina Interna. Hospital Nuestra Señora de Sonsoles. Ávila (España) 4 Servicio de Medicina Interna. Hospital Universitario Río Hortega. Valladolid (España) 5 Gerencia de Atención Primaria. Salamanca (España) 6 Departamento de Cirugía, Oftalmología, Otorrinolaringología y Fisioterapia. Facultad de Medicina. Universidad de Valladolid. Valladolid (España) 7 Departamento de Medicina. Unidad de Toxicología Clínica. Universidad de Valladolid. Valladolid (España) 8 Servicio de Medicina Interna. Hospital Universitario Río Hortega. Universidad de Valladolid. Valladolid (España)","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45940639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¿Se puede diagnosticar una enfermedad genética en base a caracteres fenotípicos? A propósito de un caso de pseudohipoparatiroidismo en Ecuador","authors":"A. Mestanza, R. Germán, E. L. Gavilanez","doi":"10.4321/s1889-836x2020000400006","DOIUrl":"https://doi.org/10.4321/s1889-836x2020000400006","url":null,"abstract":"","PeriodicalId":42821,"journal":{"name":"Revista de Osteoporosis y Metabolismo Mineral","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49439823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}