Gazi Medical Journal最新文献_第9页

Inadequate Amyloid Clearance in Alzheimer's Disease: The Possible Role of TTR Transporter Protein and LRP-1 Receptor 阿尔茨海默病中淀粉样蛋白清除不足:TTR转运蛋白和LRP-1受体的可能作用

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.23

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Depression at Health Schools 健康学校的抑郁症

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.7

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A Detailed Topographic Neurovascular Anatomy for Vestibular Neurosurgery 前庭神经外科的详细神经血管解剖

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.10

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“Universal Tumor” for a Reason, Uncommon Lipoma over Thumb 拇指上罕见脂肪瘤是“万能瘤”的原因

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.19

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Endoplasmic Reticulum Stress Response in Non-Alcholic Fatty Liver Disease: Sophisticated Pathways 非酒精性脂肪肝的内质网应激反应：复杂的途径

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.20

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Karaciger Fibrozisinde Sinyal Yolaklari Sinyal Yolaklari纤维

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.24

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Association between Postoperative Neutrophil/Lymphocyte Ratio, Neutrophil/Platelet Ratio with Mortality after Off-Pump Cardiac Surgery in Premature Newborns 早产儿无泵心脏手术后中性粒细胞/淋巴细胞比率、中性粒细胞/血小板比率与死亡率的关系

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.9

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Plasma Ghrelin Levels to Predict Severity of Pulmonary Arterial Hypertension Ghrelin in Relation to Pulmonary Hypertension 血浆Ghrelin水平预测肺动脉高压的严重程度

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.13

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Thyroid Dysfunction in Exacerbation of Chronic Obstructive Pulmonary Disease 慢性阻塞性肺疾病加重期甲状腺功能障碍

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.4

Kronik Obstrüktif Akciğer Hastalığı Alevlenmesinde Tiroid Disfonksiyonu, S. Bahçeci̇oğlu, E. Koç, T. Akkale, M. Yalçın, N. Köktürk

{"title":"Thyroid Dysfunction in Exacerbation of Chronic Obstructive Pulmonary Disease","authors":"Kronik Obstrüktif Akciğer Hastalığı Alevlenmesinde Tiroid Disfonksiyonu, S. Bahçeci̇oğlu, E. Koç, T. Akkale, M. Yalçın, N. Köktürk","doi":"10.12996/gmj.2023.4","DOIUrl":"https://doi.org/10.12996/gmj.2023.4","url":null,"abstract":"Introduction: Chronic obstructive pulmonary disease (copd) is a devastating lung disease which could be related with systemic consequences. Chronic comorbidities either develop independently or in association with systemic manifestation could lead increase morbidity or mortality in copd. thyroid gland dysfunctions are also a comorbidity that can accompany copd patients. This study was undertaken to study to show the distribution of thyroid hormone dysfunction in the setting of exacerbation in patients with Copd. Methods: A group of 105 hospitalized copd patients were included to this cross-sectional study to evaluate the thyroid hormone dysfunction in the setting of exacerbation in patients with Copd. Results: We Included 105 patients to the study,but 26 individuals were excluded due to the effect of steroid use on thyroid functions and one for sick euthyroid syndrome with low t4 serum levels.the patients were stratified into 2 subsets according to tsh concentrations:sick euthyroid syndrome and normal euthyroid function.32% of patients had normal euthyroid function,68% of them were sick euthyroid syndrome.We observed significant decrease of both po 2 and pco 2 in sick euthyroid syndrome patients(po 2 : 53.35mmhg±10.55 vs. and 61.24mmhg±12.36 patients with normal thyroid function;p=0,022; pco 2 : 39.35mmhg±8.08 vs. and 47,88mmhg±13.96 patients with normal thyroid function; P=0,017). Conclusion: We found low pO 2 and pCO 2 in patients with NTIS compared to patients with normal thyroid function.This results are some similarities with the arterial blood gas values of patients with hypothyroidism.pO 2 was low in both hypothyroidism and NTIS .But we found lower pCO 2 which was different from hypothyroid COPD patients.Lowering pCO 2 can be the compansation of the body from hypoxic conditions.","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46346625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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The Value of POSSUM & P-POSSUM as Surgical Audit Tool Predicting Morbidity and Mortality in Emergency Laparotomy POSSUM和P-POSSUM作为预测急诊剖腹手术发病率和死亡率的手术审计工具的价值

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Gazi Medical Journal Pub Date : 2023-01-01 DOI: 10.12996/gmj.2023.3

Abdul Hadi Anuar, Mohd Nizam Md Hashim, Z. Zakaria, Wan Zainira Wan Zain, S. Aziz, Siti Rahmah, H. Merican, Rosnelifaizur Ramely, Wan Mokhzani Wan Mokhter, I. S. Mohamad, F. Hayati, Nik Amin, Sahid Nik Lah, A. Zakaria

{"title":"The Value of POSSUM & P-POSSUM as Surgical Audit Tool Predicting Morbidity and Mortality in Emergency Laparotomy","authors":"Abdul Hadi Anuar, Mohd Nizam Md Hashim, Z. Zakaria, Wan Zainira Wan Zain, S. Aziz, Siti Rahmah, H. Merican, Rosnelifaizur Ramely, Wan Mokhzani Wan Mokhter, I. S. Mohamad, F. Hayati, Nik Amin, Sahid Nik Lah, A. Zakaria","doi":"10.12996/gmj.2023.3","DOIUrl":"https://doi.org/10.12996/gmj.2023.3","url":null,"abstract":"Introduction: Improvement of surgical outcomes in emergency laparotomy surgery remained dubious. Physiology and Operative Severity Score for the enumeration of Mortality (POSSUM) and Portsmouth-POSSUM (P-POSSUM) have been validated in multiple studies. The objective of this study is to determine the value of both as surgical audit tool predicting the morbidity and mortality of emergency laparotomy in a single tertiary centre in Malaysia. Methods: A retrospective review was performed in Hospital Universiti Sains Malaysia after obtaining ethical approval. All adult subjects that underwent emergency abdominal surgery from 2012 until 2015 were reviewed. Data collected were subjects' demography, clinical-pathological profiles and clinical pathway characteristics. Expected morbidity and mortality were calculated using POSSUMs risk prediction model and subsequently compared against the observed outcome. The risk prediction model was analyzed using Hosmer and Lemeshow Goodness of Fit statistical test. Results: Eighty-three (83) subjects were analyzed in this study. The proportion of 30-day in-hospital morbidity was 44 (53.0%) subjects and in-hospital mortality was 12 (14.5%) subjects. Eighteen subjects that developed in-hospital morbidity had suffered a respiratory complication. The observed-to-expected ratio of POSSUM predicting morbidity was 0.9 and P-POSSUM predicting morbidity was 0.8. However, using Hosmer and Lemershow Goodness of Fit statistical analysis, the p-value of less than 0.05 showed both POSSUM and P-POSSUM predicted poor morbidity and mortality across all risk stratifications in this population. Conclusions: POSSUM and P-POSSUM are not suitable for surgical audit tool in this centre because both produce a poor prediction of in-hospital morbidity and mortality in emergency laparotomy.","PeriodicalId":42791,"journal":{"name":"Gazi Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49276330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0