Hypertension Research in Pregnancy最新文献_第5页

Pregnant women with previous bariatric surgery are at high risk of preeclampsia: A multicenter case series and narrative literature review 既往做过减肥手术的孕妇患先兆子痫的风险高:一项多中心病例系列和叙述性文献综述

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-014

M. Morikawa, Mana Obata-Yasuoka, T. Miyake, M. Kasai, Yuzo Uchida, Hiromi Hamada, T. Kimura, H. Watari

{"title":"Pregnant women with previous bariatric surgery are at high risk of preeclampsia: A multicenter case series and narrative literature review","authors":"M. Morikawa, Mana Obata-Yasuoka, T. Miyake, M. Kasai, Yuzo Uchida, Hiromi Hamada, T. Kimura, H. Watari","doi":"10.14390/jsshp.hrp2021-014","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2021-014","url":null,"abstract":"Aim: This study aimed to clarify outcomes of pregnancies in women with previous bariatric surgery (BS). Methods: A national questionnaire was conducted targeting all 408 perinatal institutions in Japan. Reponses were obtained from 229 institutions, of which four reported a total of five singleton pregnancies and subsequent deliveries in women with previous BS in 2018. Outcomes of these women (BS group) were investigated. Case presentations: One woman (20.0%) delivered without preeclampsia prior to undergoing BS. Among the five women, median maternal age was 36 years, and median interval between previous BS and conception was 28 months. Mean maternal body mass index decreased by 10.5 between BS and conception and increased by 4.57 between conception and delivery. Three women (60.0%) developed preeclampsia (hypertension and proteinuria), two women had chronic hypertension at conception that developed into superimposed preeclampsia, and one woman had new-onset preeclampsia. Three women (60.0%) had type 2 diabetes mellitus (including overt diabetes in pregnancy), and none had new-onset gestational diabetes mellitus. One woman had a preterm delivery at 32 gestational weeks via cesarean section due to abruptio placentae caused by preeclampsia. All five women gave birth to live appropriate-for-gestational age infants with no abnormalities. Conclusion: The incidence of preeclampsia is high among pregnant women with previous BS who have diabetes mellitus at conception.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66621444","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Super-obese pregnancy - understanding the difference from a normal pregnancy and using early multidisciplinary intervention can lead to good outcomes: a case report 超级肥胖妊娠——了解与正常妊娠的区别，并采用早期多学科干预可以带来良好的结果:一份病例报告

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-002

T. Arai, S. Tanabe, I. Honda, A. Kohyama

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Influence of platelet counts on postpartum hemorrhage in elective cesarean section for Japanese twins 血小板计数对日本双胎择期剖宫产术后出血的影响

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-005

Yoshie Shibata, Miwa Miyazaki, Z. Hayashi, Shunji Suzuki

引用次数: 1

Diagnosis and management of fetal growth restriction and uteroplacental dysfunction in hypertensive disorders of pregnancy in Japan: a nationwide survey by the Japan Society for the Study of Hypertension in Pregnancy (JSSHP) 日本妊娠期高血压疾病中胎儿生长受限和子宫胎盘功能障碍的诊断和处理:日本妊娠期高血压研究协会(JSSHP)的一项全国性调查

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-010

K. Mimura, K. Takagi, Hirotada Suzuki, T. Iriyama, H. Seki

引用次数: 0

High serum concentrations of lipopolysaccharide binding protein in pregnancies with pre-eclampsia 妊娠子痫前期血清脂多糖结合蛋白的高浓度

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2021-01-01 DOI: 10.14390/jsshp.hrp2021-013

Y. Sakabe, H. Nishizawa, Asuka Kato, Hikari Yoshizawa, Yoshiteru Noda, Akiko Ohwaki, T. Sekiya, Takuma Fujii, H. Kurahashi

{"title":"High serum concentrations of lipopolysaccharide binding protein in pregnancies with pre-eclampsia","authors":"Y. Sakabe, H. Nishizawa, Asuka Kato, Hikari Yoshizawa, Yoshiteru Noda, Akiko Ohwaki, T. Sekiya, Takuma Fujii, H. Kurahashi","doi":"10.14390/jsshp.hrp2021-013","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2021-013","url":null,"abstract":"Aim: Pre-eclampsia is considered a multi-factorial disease, in which both fetal and maternal factors are involved in its onset. In this study, we aimed to test the longstanding hypothesis that the immune response to bacterial endotoxin could explain the etiology of pre-eclampsia. Methods: Serum lipopolysaccharide binding protein (LBP) concentrations and the vaginal microbiome were compared between subjects with pre-eclampsia and those with normotensive pregnancies. Results: Serum LBP concentrations were higher in subjects with pre-eclampsia compared to those with normotensive pregnancies. LBP concentrations were poorly correlated with disease onset, blood pressure, birthweight, and placental weight. Moreover, there was no evidence of bacterial species specific to pre-eclampsia based on a comparative analysis of the vaginal microbiome of subjects with pre-eclampsia and those with normotensive pregnancies. Conclusion: Serum LBP concentrations were significantly higher in subjects with pre-eclampsia compared to those with normotensive pregnancies. The clinical significance of high serum LBP concentrations in pre-eclampsia requires further investigation.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":"1 1","pages":""},"PeriodicalIF":0.2,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"66621891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Journal Awards for the Year 2019 2019年度期刊奖

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2020-11-30 DOI: 10.14390/jsshp.8.31

引用次数: 0

Intrauterine gauze or balloon tamponade for the management of postpartum hemorrhage due to uterine atony during maternal transportation 宫内纱布或球囊填塞治疗产妇运输过程中子宫张力紧张引起的产后出血

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2020-11-30 DOI: 10.14390/jsshp.hrp2020-003

Toru Kobayashi, Toshitaka Tanaka, M. Kawata, K. Oguma, Saki Ito, N. Matsuzawa, Y. Murase, Shotaro Yata, Satomi Tanaka, H. Kaneda

{"title":"Intrauterine gauze or balloon tamponade for the management of postpartum hemorrhage due to uterine atony during maternal transportation","authors":"Toru Kobayashi, Toshitaka Tanaka, M. Kawata, K. Oguma, Saki Ito, N. Matsuzawa, Y. Murase, Shotaro Yata, Satomi Tanaka, H. Kaneda","doi":"10.14390/jsshp.hrp2020-003","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2020-003","url":null,"abstract":"Aim: This study aimed to evaluate the effectiveness of intrauterine gauze or balloon tamponade for the management of postpartum hemorrhage due to uterine atony during maternal transportation from private clinics to higher-level facilities. Methods: A total of 1,428 patients were transported to the Department of Obstetrics, Juntendo University Shizuoka Hospital, between January 2008 and December 2019. Among these, 42 patients had postpartum hemorrhage due to uterine atony. Of the 42 patients, 29 (69.0%) were treated with intrauterine gauze or balloon tamponade before transportation (tamponade group); no intrauterine packing was performed in the remaining 13 (31.0%) (non-tamponade group). The primary outcome was the rate of critical obstetrical hemorrhage at hospital arrival. Secondary outcomes were blood loss before and after transportation, hemoglobin, platelets, fibrinogen, amount of blood transfusion, and rate of transfusion. Results: The rate of critical obstetrical hemorrhage was significantly lower in the tamponade group (34.5% (10/29)) compared to the non-tamponade group (76.9% (10/13)). Moreover, total blood loss during transportation and after hospital arrival was significantly lower in the tamponade group (487 ± 331 g) compared to the non-tamponade group (1,199 ± 1,012 g).","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44017501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Committee for Academic Affairs JSSHP Research Award 2020 Clinical Research and Basic Research 学术委员会JSSHP研究奖2020年临床研究和基础研究

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2020-11-30 DOI: 10.14390/jsshp.8.33

引用次数: 0

Pathophysiological roles of ADMA-mediated endothelial injury in hypertensive disorders of pregnancy ADMA介导的内皮损伤在妊娠期高血压疾病中的病理生理作用

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2020-11-30 DOI: 10.14390/jsshp.hrp2019-013

Takashi Kobayashi, S. Ueda, M. Takagi, M. Kihara, Yusuke Suzuki

{"title":"Pathophysiological roles of ADMA-mediated endothelial injury in hypertensive disorders of pregnancy","authors":"Takashi Kobayashi, S. Ueda, M. Takagi, M. Kihara, Yusuke Suzuki","doi":"10.14390/jsshp.hrp2019-013","DOIUrl":"https://doi.org/10.14390/jsshp.hrp2019-013","url":null,"abstract":"Hypertensive disorders of pregnancy (HDP) represent a major cause of maternal and neonatal morbidity and mortality. Studies conducted over the last decade have improved our understanding of the potential mechanisms underlying HDP pathogenesis. The first step in HDP is reduced uteroplacental perfusion as a result of abnormal extravillous trophoblast invasion of spiral arterioles. Subsequent placental ischemia leads to maternal vascular endothelial dysfunction that may be caused by an imbalance between pro- and anti-angiogenic factors, enhanced formation of vasocontractile factors such as endothelin and thromboxane, increased vascular sensitivity to angiotensin II, and/or decreased formation of vasodilators such as nitric oxide (NO) and prostaglandin I2. NO is one of the major mediators from the endothelium, and its production is modified by endogenous NO synthase inhibitors such as asymmetric dimethylarginine (ADMA). ADMA levels are generally higher in patients with cardiovascular and metabolic diseases and widely recognized as a prognostic marker for major cardiovascular events and mortality. Recent studies have found ADMA levels to be higher in patients with preeclampsia. In addition, multiple studies indicate that elevated ADMA in early stages of pregnancy might predict the development of preeclampsia. Finally, ADMA has been found to be associated with uterine artery flow disturbance. Collectively, these findings strongly suggest that elevated ADMA-mediated endothelial dysfunction could be a causative factor for HDP. In this review, we discuss the biology of ADMA, with a particular focus on its potential role in HDP.","PeriodicalId":42505,"journal":{"name":"Hypertension Research in Pregnancy","volume":" ","pages":""},"PeriodicalIF":0.2,"publicationDate":"2020-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48695518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Best Reviewer Awards 最佳评论家奖

IF 0.2

Hypertension Research in Pregnancy Pub Date : 2020-11-30 DOI: 10.14390/jsshp.8.32

引用次数: 0