QUADERNI URBINATI DI CULTURA CLASSICA最新文献

Catching the collapse of time : reading Ornytus in Statius' Thebaid 12 through Malone in Samuel Beckett's The Unnamable 捕捉时间的崩塌:读斯塔提乌斯《底比斯》中的奥尼图斯，读塞缪尔·贝克特《无名》中的马龙

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2019-01-01 DOI: 10.19272/201906402008

Tim Noens

引用次数: 0

[Plut.] Mus. 15, 1136b-c : un nuovo frammento di Melanippide? [Plut。15 1136b-c:一种新的黑色素碎片?

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2017-01-01 DOI: 10.19272/201706403002

M. Ercoles

引用次数: 1

Observations d'Hipparque d’Hipparque评论

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2017-01-01 DOI: 10.19272/201706401011

H. Perdicoyianni-Paléologou

引用次数: 0

Non elaboratum ad pedem (Hor. Ep. 14, 6-12) : le sorti alterne del metro anacreonteo a Roma 《非精加工》（Hor.Ep.14，6-12）：罗马anacreontean计量器的另一种命运

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2017-01-01 DOI: 10.19272/201706403007

Lorenzo Bucceroni

引用次数: 0

La Nekyia omerica nella traduzione di Cesare Pavese 凯撒·帕维斯翻译中的Nekyia omerica

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2017-01-01 DOI: 10.19272/201706401015

L. Vitacolonna

引用次数: 0

Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts. 巨细胞病毒感染的早期阶段会抑制人成纤维细胞中宿主 microRNA 的表达调控。

IF 4.3 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2016-12-16 DOI: 10.1080/15384101.2016.1241928

Anton A Buzdin, Alina V Artcibasova, Natalya F Fedorova, Maria V Suntsova, Andrew V Garazha, Maxim I Sorokin, Daria Allina, Mikhail Shalatonin, Nikolay M Borisov, Alex A Zhavoronkov, Igor Kovalchuk, Olga Kovalchuk, Alla A Kushch

{"title":"Early stage of cytomegalovirus infection suppresses host microRNA expression regulation in human fibroblasts.","authors":"Anton A Buzdin, Alina V Artcibasova, Natalya F Fedorova, Maria V Suntsova, Andrew V Garazha, Maxim I Sorokin, Daria Allina, Mikhail Shalatonin, Nikolay M Borisov, Alex A Zhavoronkov, Igor Kovalchuk, Olga Kovalchuk, Alla A Kushch","doi":"10.1080/15384101.2016.1241928","DOIUrl":"10.1080/15384101.2016.1241928","url":null,"abstract":"Responses to human cytomegalovirus (HCMV) infection are largely individual and cell type specific. We investigated molecular profiles in 2 primary cell cultures of human fibroblasts, which are highly or marginally sensitive to HCMV infection, respectively. We screened expression of genes and microRNAs (miRs) at the early (3 hours) stage of infection. To assess molecular pathway activation profiles, we applied bioinformatic algorithms OncoFinder and MiRImpact. In both cell types, pathway regulation properties at mRNA and miR levels were markedly different. Surprisingly, in the infected highly sensitive cells, we observed a \"freeze\" of miR expression profiles compared to uninfected controls. Our results evidence that in the sensitive cells, HCMV blocks intracellular regulation of microRNA expression already at the earliest stage of infection. These data suggest somewhat new functions for HCMV products and demonstrate dependence of miR expression arrest on the host-encoded factors.","PeriodicalId":42434,"journal":{"name":"QUADERNI URBINATI DI CULTURA CLASSICA","volume":"53 1","pages":"3378-3389"},"PeriodicalIF":4.3,"publicationDate":"2016-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90274447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Physiological Characterization of Connexin41.8 and Connexin39.4, Which Are Involved in the Striped Pattern Formation of Zebrafish. 参与斑马鱼条纹图案形成的Connexin41.8和Connexin39.4的生理学特征。

3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2016-01-15 Epub Date: 2015-11-23 DOI: 10.1074/jbc.M115.673129

Masakatsu Watanabe, Risa Sawada, Toshihiro Aramaki, I Martha Skerrett, Shigeru Kondo

{"title":"The Physiological Characterization of Connexin41.8 and Connexin39.4, Which Are Involved in the Striped Pattern Formation of Zebrafish.","authors":"Masakatsu Watanabe, Risa Sawada, Toshihiro Aramaki, I Martha Skerrett, Shigeru Kondo","doi":"10.1074/jbc.M115.673129","DOIUrl":"10.1074/jbc.M115.673129","url":null,"abstract":"The zebrafish has a striped skin pattern on its body, and Connexin41.8 (Cx41.8) and Cx39.4 are involved in striped pattern formation. Mutations in these connexins change the striped pattern to a spot or labyrinth pattern. In this study, we characterized Cx41.8 and Cx39.4 after expression in Xenopus oocytes. In addition, we analyzed Cx41.8 mutants Cx41.8I203F and Cx41.8M7, which caused spot or labyrinth skin patterns, respectively, in transgenic zebrafish. In the electrophysiological analysis, the gap junctions formed by Cx41.8 and Cx39.4 showed distinct sensitivity to transjunctional voltage. Analysis of non-junctional (hemichannel) currents revealed a large voltage-dependent current in Cx39.4-expressing oocytes that was absent in cells expressing Cx41.8. Junctional currents induced by both Cx41.8 and Cx39.4 were reduced by co-expression of Cx41.8I203F and abolished by co-expression of Cx41.8M7. In the transgenic experiment, Cx41.8I203F partially rescued the Cx41.8 null mutant phenotype, whereas Cx41.8M7 failed to rescue the null mutant, and it elicited a more severe phenotype than the Cx41.8 null mutant, as evidenced by a smaller spot pattern. Our results provide evidence that gap junctions formed by Cx41.8 play an important role in stripe/spot patterning and suggest that mutations in Cx41.8 can effect patterning by way of reduced function (I203F) and dominant negative effects (M7). Our results suggest that functional differences in Cx41.8 and Cx39.4 relate to spot or labyrinth mutant phenotypes and also provide evidence that these two connexins interact in vivo and in vitro. ","PeriodicalId":42434,"journal":{"name":"QUADERNI URBINATI DI CULTURA CLASSICA","volume":"24 1","pages":"1053-63"},"PeriodicalIF":0.0,"publicationDate":"2016-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4714190/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90250460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"历史学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Greek Hepatoscopy and its Criteria 希腊肝镜检查及其标准

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2016-01-01 DOI: 10.1400/241598

T. Vítek

引用次数: 0

L’accoglienza nel mondo antico 欢迎来到古代世界

IF 0.1 3区历史学

QUADERNI URBINATI DI CULTURA CLASSICA Pub Date : 2016-01-01 DOI: 10.19272/201606403007

Manieri Alessandra

引用次数: 0

Meleagro e la viola bianca della poesia (AP 4, 1, 55 S. = HE 3980 S.) 梅莱格罗与诗歌的白紫色（AP 4，1.55 S.=HE 3980 S.）