Journal of Fetal Medicine最新文献

Monochorionic Twin Pregnancy Complicated by Arrhythmia in One Twin: Longitudinal Hemodynamic Effects of Flecainide Cardioversion Assessed by Fetal Venous Doppler 单绒毛膜双胎妊娠合并一胎心律失常:胎儿静脉多普勒评价氟屈奈复律对纵向血流动力学的影响

Journal of Fetal Medicine Pub Date : 2023-11-06 DOI: 10.1055/s-0043-1774753

Anders Einum, Philip von Brandis, Elisabeth Leirgul, Cathrine Ebbing

引用次数: 0

Klippel–Trenaunay–Weber Syndrome—Case Report: Diagnostic Role of Fetal Autopsy and Histopathology klippel - trenauny - weber综合征病例报告:胎儿尸检和组织病理学的诊断作用

Journal of Fetal Medicine Pub Date : 2023-10-13 DOI: 10.1055/s-0043-1774756

Poornima Sharma, Shreya Singh Kushwaha, Suchandana Dasgupta, Sumitra Bachani

{"title":"Klippel–Trenaunay–Weber Syndrome—Case Report: Diagnostic Role of Fetal Autopsy and Histopathology","authors":"Poornima Sharma, Shreya Singh Kushwaha, Suchandana Dasgupta, Sumitra Bachani","doi":"10.1055/s-0043-1774756","DOIUrl":"https://doi.org/10.1055/s-0043-1774756","url":null,"abstract":"Abstract Objectives The aim of this study was to evaluate a case of Klippel–Trenaunay–Weber Syndrome (KTWS) diagnosed at 15 weeks of gestation. Materials and Methods A 30-year-old G4P1L1A2 at 15 weeks gestation was detected with abnormal fetal right lower limb thickness and hypervascularity in both thighs. Multiseptated hypoechoic areas were detected involving skin and subcutaneous tissue of the left shoulder region, axilla, chest wall, and lower back region posteriorly extending into both lower limbs associated with cortical thickening of long bones of the lower limb. Significant subcutaneous thickening was present in the right foot along with a slow flow vascular malformation. The couple did not opt for any prenatal testing and continued the pregnancy. Results The patient received routine antenatal care and at 27 weeks of gestation there was polyhydramnios with fetal demise. She delivered a macerated stillborn baby girl weighing 2.5 kg (>99th centile). Consent was obtained for external autopsy, fetal photographs, and tissue biopsy. The fetus was grossly macerated. The skin was hypertrophied and subcutaneous tissue along with bluish discoloration was present over the affected areas. Histopathology of fetal thigh tissue was suggestive of arteriovenous malformation compatible with a diagnosis of KTWS. Conclusions KTWS has unique sonographic features. Confirmation can be done by clinical exome sequencing of amniotic fluid or fetal tissue.","PeriodicalId":42412,"journal":{"name":"Journal of Fetal Medicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135853881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Demonstration of Double Aortic Arch in a 21 Weeks Primigravida by Color Spatiotemporal Image Correlation Rendering Technique 用彩色时空图像相关渲染技术显示21周初诊双主动脉弓

Journal of Fetal Medicine Pub Date : 2023-10-13 DOI: 10.1055/s-0043-1774755

Shankar Dey

引用次数: 0

A Rare Case of Fetal Hydrocolpos Secondary to Low Vaginal Atresia 继发于阴道低位闭锁的胎儿阴积水1例

Journal of Fetal Medicine Pub Date : 2023-10-13 DOI: 10.1055/s-0043-1774754

Athira Rajamma, Megha Venkataraman

引用次数: 0

Congenital Intracranial Teratoma: Management Challenges! 先天性颅内畸胎瘤:管理挑战!

Journal of Fetal Medicine Pub Date : 2023-10-10 DOI: 10.1055/s-0043-1771523

Saiseema V. Sarva, Megha Venkataraman

{"title":"Congenital Intracranial Teratoma: Management Challenges!","authors":"Saiseema V. Sarva, Megha Venkataraman","doi":"10.1055/s-0043-1771523","DOIUrl":"https://doi.org/10.1055/s-0043-1771523","url":null,"abstract":"Abstract Congenital brain tumors are extremely rare. Among them teratomas are the most common. They make up one-third of all congenital brain tumors. Late diagnosis, poor prognosis, and majority being delivered by cesarean section (subjecting the mother to increased morbidity) add to the complexities and challenges of the case. We report a rare case of a massive congenital brain tumor diagnosed prenatally on ultrasound. Because of the poor prognosis and associated craniomegaly, pregnancy termination was contemplated at 28 weeks aiming at vaginal delivery, despite a high probability of an eventual cesarean delivery due to the associated macrocrania. Intrapartum second stage of labor was protracted due to nondescent of the large head; however, providentially there was timely skull rupture of the fetus facilitating a vaginal delivery. The cerebral tumor was confirmed at autopsy to be an immature teratoma. There were no other associated malformations. Ultrasound has emerged as major modality in prenatal diagnosis aiding the antenatal preparation of the prospective parents and the multidisciplinary team for the poor outcome. The knowledge gained and anticipated prognosis help immensely in planning the management, thereby avoiding subjecting the woman to cesarean section and its morbidity.","PeriodicalId":42412,"journal":{"name":"Journal of Fetal Medicine","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136293620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemolytic Disease of the Fetus and Newborn: Understanding the Testing Needed to Confirm the Identity of the Causative Antibody 胎儿和新生儿溶血性疾病:了解确认致病抗体身份所需的检测

Journal of Fetal Medicine Pub Date : 2023-10-10 DOI: 10.1055/s-0043-1771524

Jeremy Jacobs, Elizabeth Abels

{"title":"Hemolytic Disease of the Fetus and Newborn: Understanding the Testing Needed to Confirm the Identity of the Causative Antibody","authors":"Jeremy Jacobs, Elizabeth Abels","doi":"10.1055/s-0043-1771524","DOIUrl":"https://doi.org/10.1055/s-0043-1771524","url":null,"abstract":"A recent article by Beck et al[1] contributes to our understanding of hemolytic disease of the fetus and newborn (HDFN) mediated by antibodies against non-Rhesus blood group antigen systems. However, there are critical methodological and reporting errors that preclude the ability to draw the conclusions asserted by the authors. First, the authors provide no compelling evidence that the antibody causing the fetal anemia is due to anti-M other than a positive indirect antiglobulin test (IAT) for anti-M in maternal plasma and a coincidentally positive direct antiglobulin test (DAT) on neonatal cells. The authors provide no information regarding plasma studies in the newborn, elution studies, low-incidence antibody testing, or newborn M antigen typing. A positive newborn DAT is nondiagnostic and requires further evaluation, as even a negative maternal IAT does not preclude the possibility of HDFN to a low-incidence maternal alloantibody.[2] Further, contemporary and historical literature of larger case series found that in HDFN caused by anti-M the neonatal DAT is more frequently negative than positive.[2] [3] [4] Therefore, the positive DAT cited by Beck et al could theoretically lower one's suspicion for the cause of HDFN being solely due to anti-M. In addition, when discussing any case of HDFN, but especially with anti-M where the antibody's isotype and reacting temperature can be in question, the testing methods including platform technology, temperature, and enhancement media are vital to the discussion.[5] Beck et al provide no information regarding the antibody identification or titer techniques used in the maternal or neonatal testing nor do the authors provide methodological description of the maternal breast milk testing. Though this case could be an important addition to the growing body of evidence supporting anti-M as a cause of HDFN, further investigation and reporting are required to definitively establish the conclusions proclaimed by the authors.","PeriodicalId":42412,"journal":{"name":"Journal of Fetal Medicine","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136293768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetal Autopsy—A Game Changer! 胎儿尸检--游戏规则的改变者！

IF 0.2

Journal of Fetal Medicine Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1776056

R. Elayedatt, V. Krishnan, Vidya Chandraprabha

引用次数: 0

Final Commentary on Anti-M Alloimmunization Following Term Stillbirth: A Case Report and Review of the Literature 关于足月死胎后抗 M 免疫的最终评论：病例报告与文献综述

IF 0.2

Journal of Fetal Medicine Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1777800

Ashok Khurana, Mohd Faisal Khan

引用次数: 0

Aberrant Right Subclavian Artery—To Test or Not to Test, That Is the Question 右锁骨下动脉异常--检测还是不检测，这是一个问题

IF 0.2

Journal of Fetal Medicine Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1776057

Gurnihal Chawla, B. Balakrishnan, Meenu Batra, Afshana Sidhik, Aditi Laad, S. N. Patil, Lipi Madhusoodhanan, K. K. Gopinathan

{"title":"Aberrant Right Subclavian Artery—To Test or Not to Test, That Is the Question","authors":"Gurnihal Chawla, B. Balakrishnan, Meenu Batra, Afshana Sidhik, Aditi Laad, S. N. Patil, Lipi Madhusoodhanan, K. K. Gopinathan","doi":"10.1055/s-0043-1776057","DOIUrl":"https://doi.org/10.1055/s-0043-1776057","url":null,"abstract":"Abstract Objectives This study aimed to determine if isolated fetal aberrant right subclavian artery (ARSA) is associated with an increased risk of chromosomal abnormalities and to see whether or not invasive testing should be considered. Methods We conducted a retrospective study from January 2017 to December 2021. All prenatally diagnosed cases of ARSA were reviewed and their clinical data were collected. Amniocentesis was advised after genetic counseling in every case of ARSA. Results One hundred and thirteen patients of ARSA were diagnosed at 21.2 ± 2.4 weeks of gestational age. Eighty-eight fetuses had isolated ARSA. Eighty-three patients underwent amniocentesis. Of those, six had Down syndrome and one had Turner syndrome. Four fetuses with genetic abnormalities had no other ultrasound findings; however, the association of isolated ARSA with chromosomal abnormalities was not statistically significant ( p -value = 0.998). Ten patients underwent termination of pregnancy including seven with chromosomal abnormalities and three fetuses with other structural anomalies. The mean age of postnatal follow-up was 2.2 years. Mild respiratory distress was seen in one fetus. No neonatal intensive care unit admissions were present. Conclusion Isolated ARSA by itself does not significantly increase the risk of associated chromosomal abnormalities. The detection of fetal ARSA, however, mandates a detailed fetal ultrasound. Invasive testing can be deferred in cases of isolated ARSA. Larger prospective studies are required to see the role of cell-free DNA as an optimal alternative option.","PeriodicalId":42412,"journal":{"name":"Journal of Fetal Medicine","volume":"86 1","pages":"107 - 111"},"PeriodicalIF":0.2,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139344313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fetal Abdominal Cyst as a Stage of Meconium Peritonitis after Fetoscopic Laser Photocoagulation 胎儿腹腔镜激光光凝术后胎儿腹腔囊肿是蜕膜性腹膜炎的一个阶段

IF 0.2

Journal of Fetal Medicine Pub Date : 2023-09-01 DOI: 10.1055/s-0043-1776322

Iryna Tsikhanenka, Maxim Beluga, Venera Semenchuk, Ivan Kurlovich, Ella Marahovskaya

引用次数: 0