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COVID-19 vaccines in elderly subjects: Considerations on efficacy and safety 老年受试者COVID-19疫苗的有效性和安全性考虑
Archives of Clinical Gastroenterology Pub Date : 2021-04-22 DOI: 10.17352/2455-2283.000093
M. Bongiovanni
{"title":"COVID-19 vaccines in elderly subjects: Considerations on efficacy and safety","authors":"M. Bongiovanni","doi":"10.17352/2455-2283.000093","DOIUrl":"https://doi.org/10.17352/2455-2283.000093","url":null,"abstract":"The coronavirus disease-2019 (COVID-19) is primarily a disease of the respiratory system and is manifested by an infectious pneumonia, with fever, cough and breathlessness as the most common presenting symptoms.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123256304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Non-Alcoholic Fatty Liver Disease (NAFLD) in overweight and obese children and adolescents 超重和肥胖儿童和青少年的非酒精性脂肪性肝病(NAFLD
Archives of Clinical Gastroenterology Pub Date : 2020-12-23 DOI: 10.17352/2455-2283.000086
Schiel Ralf, Heinrichs Mario, Stein Gunter, Bambauer Rolf, Steveling Antje
{"title":"Non-Alcoholic Fatty Liver Disease (NAFLD) in overweight and obese children and adolescents","authors":"Schiel Ralf, Heinrichs Mario, Stein Gunter, Bambauer Rolf, Steveling Antje","doi":"10.17352/2455-2283.000086","DOIUrl":"https://doi.org/10.17352/2455-2283.000086","url":null,"abstract":"Over the last decades overweight, obesity and non-alcoholic fatty liver disease (NAFLD) in childhood and adolescence increased. NAFLD is strongly associated with insulin resistance, hypertension, dyslipidemia and other pro-atherogenic conditions.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126834998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Characterization of patients diagnosed with drug-induced liver injury 诊断为药物性肝损伤患者的特征分析
Archives of Clinical Gastroenterology Pub Date : 2020-09-28 DOI: 10.22541/au.160133597.78015154
I. Ashkenazi, Y. Lurie, A. Kenig, S. Zevin, I. Gafanovich, E. Resnick, S. Shteingart, Tali Bdolach-Abram, D. Katz
{"title":"Characterization of patients diagnosed with drug-induced liver injury","authors":"I. Ashkenazi, Y. Lurie, A. Kenig, S. Zevin, I. Gafanovich, E. Resnick, S. Shteingart, Tali Bdolach-Abram, D. Katz","doi":"10.22541/au.160133597.78015154","DOIUrl":"https://doi.org/10.22541/au.160133597.78015154","url":null,"abstract":"The coronavirus disease-2019 (COVID-19) is primarily a disease of the respiratory system and is manifested by an infectious pneumonia, with fever, cough and breathlessness as the most common presenting symptoms.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"93 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126083408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Carcinoma cuniculatum of the esophagus-diagnostic and treatment dilemma 食管癌的诊断与治疗困境
Archives of Clinical Gastroenterology Pub Date : 2020-08-13 DOI: 10.17352/2455-2283.000080
Matheus P. Falasa, Alexander Ayzengart, M. Walters, Xiuli Liu, O. Oduntan
{"title":"Carcinoma cuniculatum of the esophagus-diagnostic and treatment dilemma","authors":"Matheus P. Falasa, Alexander Ayzengart, M. Walters, Xiuli Liu, O. Oduntan","doi":"10.17352/2455-2283.000080","DOIUrl":"https://doi.org/10.17352/2455-2283.000080","url":null,"abstract":"Carcinoma cuniculatum is a rare variant of well-differentiated squamous cell carcinoma of the esophagus, with fewer than twenty cases reported in the literature [1]. Diagnosis is often delayed due to failure of endoscopic biopsies to yield a definitive tissue diagnosis. We present the case of a patient with carcinoma cuniculatum of the esophagus who was misdiagnosed as achalasia, and consequently did not undergo surgical resection of the malignancy for nine months.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"112 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132693095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Rapunzel Syndrome 长发公主综合征1例
Archives of Clinical Gastroenterology Pub Date : 2020-07-27 DOI: 10.17352/2455-2283.000079
Krisztina Csuzi, Orsolya Boda, R. Neumann, G. Tóth
{"title":"A Case of Rapunzel Syndrome","authors":"Krisztina Csuzi, Orsolya Boda, R. Neumann, G. Tóth","doi":"10.17352/2455-2283.000079","DOIUrl":"https://doi.org/10.17352/2455-2283.000079","url":null,"abstract":"Trichobezoar is a concretion of chewing and swallowing hair or any other indigestible materials that accumulate in the gastrointestinal tract. Rapunzel syndrome refers to a rare condition when a gastric trichobezoar extends into the small bowel. We describe the case of a 16-year-old female who presented with chronic abdominal pain, loss of appetite and weight loss. Based on her past medical history, trichophagia has already been revealed at preschool age. Imaging tests indicated a large filling of the stomach. Upper gastrointestinal endoscopy showed a large trichobezoar in the stomach with prolonga on through the pylorus. The patient underwent exploratory laparotomy and the trichobezoar was removed. Upper gastrointestinal endoscopy is the preferred modality for diagnosis and in most cases the treatment is surgical.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122740957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Irritable bowel syndrome and small intestinal bacterial overgrowth: Assessment with breath test 肠易激综合征和小肠细菌过度生长:呼吸试验评估
Archives of Clinical Gastroenterology Pub Date : 2020-05-30 DOI: 10.17352/2455-2283.000077
Costa La, Gomes Tnf, Braga Cu, L. Lenz, Miszputen Sj, O. Ambrogini
{"title":"Irritable bowel syndrome and small intestinal bacterial overgrowth: Assessment with breath test","authors":"Costa La, Gomes Tnf, Braga Cu, L. Lenz, Miszputen Sj, O. Ambrogini","doi":"10.17352/2455-2283.000077","DOIUrl":"https://doi.org/10.17352/2455-2283.000077","url":null,"abstract":"Background: Irritable bowel syndrome (IBS) has been considered a functional disease, however evidences suggest organic abnormalities as disbiosis. The aim of this study was to evaluate bacterial overgrowth syndrome in IBS patients. Methods: Patients with IBS were submited to the expired H2 and CH4 breath test, with analyzes of exhaled air in fasting (zero minutes) and after the administration of 10g of lactulose, at times: 15, 30, 60, 90, 120, 150 and 180 minutes. The test was considered positive when the values of H2 or CH4 at 90 minutes were 20 ppm above baseline values. Results: Fourth-six patients were included, 23 (50%) had diarrheal subtype, 12 (26.1%) had constipated subtype and 11 (23.9%) had mixed subtype. All patients were submitted to lactulose breath test (LBT), with evaluation of expired H2 and CH4. The H2 test positivity was 15.2% and the CH4 test was 10.9%. In the diarrheal subgroup, the positivity of the H2 test was 13%, and at the CH4 test was 8.7%. Among the constipated patients, 16.7% were positive for H2 test, and none was positive for CH4 test. At the mixed subtype, the H2 test was positive for 18.2% and CH4 test for 27.3%. There was no significant correlation between the positivity of expired H2 test with the diarrheal subtype, and neither the expired CH4 test with the constipated subtype. Conclusion: LBT has not altered in patients with three forms of IBS. The optimization of diagnostic methods is necessary for a more accurate diagnosis.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"25 4","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120901464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chilean experience using “Theranostics” for treating metastatic neuroendocrine tumors with [177Lu]Lu DOTA-TATE 智利“Theranostics”治疗转移性神经内分泌肿瘤的经验[177Lu]Lu DOTA-TATE
Archives of Clinical Gastroenterology Pub Date : 2020-05-27 DOI: 10.17352/2455-2283.000076
H. Amaral, R. Pruzzo, R. Fernández, V. Kramer, Cristian Soza-Ried, I. Coudeu
{"title":"Chilean experience using “Theranostics” for treating metastatic neuroendocrine tumors with [177Lu]Lu DOTA-TATE","authors":"H. Amaral, R. Pruzzo, R. Fernández, V. Kramer, Cristian Soza-Ried, I. Coudeu","doi":"10.17352/2455-2283.000076","DOIUrl":"https://doi.org/10.17352/2455-2283.000076","url":null,"abstract":"Introduction: Well-differentiated, Neuroendocrine Tumors (NET) are highly heterogenic and slow-growing pathologies, characterized by unspecific symptomatology and elevated expression of somatostatin receptors (SSTR). Despite the high incidence of NETs, several patients are diagnosed in advance stages of the disease when surgery is insufficient to treat the pathology. Peptide receptor radionuclide therapy (PRRT) has emerged as a new state-of-the-art treatment for NET-patients in advanced stages. Results: In this retrospective study, between 2004 and 2018 a total of 66 patients with advanced-stage-NETs, refractory to other therapies, were treated with [177Lu]Lu DOTA TATE. At the end of the study, 56.1% of the patients were alive and the median overall survival for all patients in the study was 86.3 months. Patients that received doses ≥ 22.2 GBq showed increased overall survival (OS) in comparison with patients that received doses < 22.2 GBq (HR, 0.168; 95%CI 0.12- 0.99; p<0.001), adjusted by gender. Likewise, patients that received doses ≥29.6 GBq had an increased OS (HR, 0.42; 95%CI 0.19-0.94, p<0.05). Conclusion: Although several studies have shown that PRRT is an effective alternative for advanced NET, patients in South America have no regular access to PRRT. Our study proves that [177Lu]Lu-DOTA-TATE effectively increases the survival of patients with metastatic NET and provides an excellent alternative in terms of cost-efficiency for South American countries.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128062001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Isolated splenic metastasis: An unusual presentation of colonic adenocarcinoma 孤立性脾转移:结肠腺癌的一种不寻常的表现
Archives of Clinical Gastroenterology Pub Date : 2019-08-24 DOI: 10.17352/2455-2283.000064
M. Aijaz, Mahboob Hasan, F. Alam
{"title":"Isolated splenic metastasis: An unusual presentation of colonic adenocarcinoma","authors":"M. Aijaz, Mahboob Hasan, F. Alam","doi":"10.17352/2455-2283.000064","DOIUrl":"https://doi.org/10.17352/2455-2283.000064","url":null,"abstract":"It is very uncommon situation in which primary colonic carcinoma is asymptomatic and presents as isolated splenic metastasis. Involvement of spleen by secondary tumors is usually seen in disseminated spread of tumor. However, isolated splenic involvement by tumor metastasis is an infrequent event, except in cases of lymphoid origin malignancy where spleen is commonly involved. We hereby report a case of 50 years old man who presented with gradually increasing pain abdomen for 3 months. USG report showed splenomegaly indicating either splenic abscess or hemangioma.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"121 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114570702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long non-coding RNA HOXA11-AS facilitates cell migration and invasion by regulating microRNA-148a/WNT1 axis in gastric cancer 长链非编码RNA HOXA11-AS通过调控microRNA-148a/WNT1轴在胃癌中促进细胞迁移和侵袭
Archives of Clinical Gastroenterology Pub Date : 2019-07-23 DOI: 10.17352/2455-2283.000063
Tao Guo, Xiao Yuan, Defeng Liu, S. Peng, A. Xu
{"title":"Long non-coding RNA HOXA11-AS facilitates cell migration and invasion by regulating microRNA-148a/WNT1 axis in gastric cancer","authors":"Tao Guo, Xiao Yuan, Defeng Liu, S. Peng, A. Xu","doi":"10.17352/2455-2283.000063","DOIUrl":"https://doi.org/10.17352/2455-2283.000063","url":null,"abstract":"Recently, long non-coding RNAs (lncRNAs) have emerged as crucial players in the initiation and \u0000progression of multiple cancers including gastric cancer (GC). LncRNA HOXA11 antisense RNA (HOXA11- \u0000AS) has been found to be an oncogenic factor in GC. However, the molecular mechanisms responsible for \u0000these oncogenic properties have not been thoroughly elucidated.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129911903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A study of post-operative complications of all emergency laparotomy in a tertiary care hospital within 90 days 某三级医院急诊剖腹手术90天内并发症分析
Archives of Clinical Gastroenterology Pub Date : 2019-07-10 DOI: 10.17352/2455-2283.000062
A. Bansal, Manaswini Mallick, S. Jena
{"title":"A study of post-operative complications of all emergency laparotomy in a tertiary care hospital within 90 days","authors":"A. Bansal, Manaswini Mallick, S. Jena","doi":"10.17352/2455-2283.000062","DOIUrl":"https://doi.org/10.17352/2455-2283.000062","url":null,"abstract":"Introduction: An emergency laparotomy is a life saving procedure undertaken mostly in acute \u0000cases without much preparation of the patient. Despite being one of the most common urgent surgical \u0000procedures, it still proves to be a challenge for the surgeons of the world.","PeriodicalId":422260,"journal":{"name":"Archives of Clinical Gastroenterology","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128072254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
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