Astim Allerji Immunoloji最新文献_第2页

Diagnostic Management of Chronic Granulomatous Disease 慢性肉芽肿性疾病的诊断处理

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Astim Allerji Immunoloji Pub Date : 2023-04-07 DOI: 10.21911/aai.237

M. Y. Koker

引用次数: 0

The Frequency and Severity of COVID-19 in Patients Receiving Biological Agents and Risk Factors: Experience of an Allergy Clinic 新冠肺炎在接受生物制剂和危险因素治疗的患者中的频率和严重程度：过敏诊所的经验

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Astim Allerji Immunoloji Pub Date : 2023-04-07 DOI: 10.21911/aai.141

Sadan Soyyigit, Ş. Beyaz, Zeynep Celebi Sozener

{"title":"The Frequency and Severity of COVID-19 in Patients Receiving Biological Agents and Risk Factors: Experience of an Allergy Clinic","authors":"Sadan Soyyigit, Ş. Beyaz, Zeynep Celebi Sozener","doi":"10.21911/aai.141","DOIUrl":"https://doi.org/10.21911/aai.141","url":null,"abstract":"Objective: The effect of biological agents used in severe allergic diseases on the risk of coronavirus disease 2019 (COVID-19) and the course of the disease still remains unclear. The aim of the study was to evaluate retrospectively the frequency and severity of COVID-19 to determine risk factors and to present real-life data in patients using biological agents.Materials and Methods: Patients who have used omalizumab or mepolizumab for at least six months were questioned retrospectively in terms of a history of COVID-19. Patients with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) polymerase chain reaction (PCR) or serological IgG positivity, symptoms, lung involvement, the need for supplemental oxygen, hospital and intensive care admission, and mortality were queried. Results: Of the 71 patients (omalizumab/mepolizumab: 51/20) included in the study, the average age was 37.2 +/- 12.9, and the female/ male ratio was 46/25. Of the 11 patients (omalizumab/mepolizumab: 6/5) with SARS-CoV-2 positivity, two were hospitalized for pneumonia and needed oxygen. However, intensive care was not required and they survived. There was no significant difference between mepolizumab users who had COVID-19 and those who did not in terms of baseline and post-treatment 6th-month eosinophil values (p= 0.7, p= 0.59, respectively). It was established that eosinopenia developing after treatment did not increase the risk of COVID-19 in patients using mepolizumab [RR (95% Cl) 0.99 (0.97-1.02), p=0.88].Conclusion: According to our single center data, we found the risk of severe COVID-19 in patients using biological agents to be quite low. Especially, eosinopenia that developed after mepolizumab treatment did not constitute a risk factor for the severity of COVID-19.","PeriodicalId":42004,"journal":{"name":"Astim Allerji Immunoloji","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48153001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Clinical and Laboratory Features of Patients with Ataxia-Telangiectasia 共济失调毛细血管扩张症患者的临床和实验室特征评价

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Astim Allerji Immunoloji Pub Date : 2023-04-07 DOI: 10.21911/aai.006

M. Kiliç, Omer Gunbey, E. Taşkin, Bunyamin Dag, Elif Kucuk, Fatma Gunbey, Aşkın Şen

引用次数: 0

In-Vitro Evaluation of Immunomodulation Effects of Mesenchymal Stem Cell-Derived Exosomes in Refractory Chronic Spontaneous Urticaria 间充质干细胞来源的外泌体对难治性慢性自发性荨麻疹免疫调节作用的体外评价

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Astim Allerji Immunoloji Pub Date : 2023-04-07 DOI: 10.21911/aai.120

Alper Tunga Ozdemir, C. Kırmaz, Rabia Bilge OZGUL OZDEMIR, M. Oztatlici, Pinar KILICARSLAN SONMEZ, M. Tuğlu

引用次数: 0

Safety Profiles of Biological Therapies Used in Asthma Treatment 用于哮喘治疗的生物疗法的安全性概况

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Astim Allerji Immunoloji Pub Date : 2022-12-07 DOI: 10.21911/aai.091

G. PAÇACI ÇETİN, B. Arslan, I. Yilmaz

引用次数: 0

The Effect of Internet Addiction on Asthma Control and Medication Adherence 网络成瘾对哮喘控制和药物依从性的影响

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Astim Allerji Immunoloji Pub Date : 2022-12-07 DOI: 10.21911/aai.685

A. F. Kalpaklioglu, A. Baccioglu, B. Dumanoğlu, M. Poyraz, Sümeyra ALAN YALIM, Gulistan Alpagat

引用次数: 0

The Distribution of Sensitization to Common Inhalant Allergens in Adult Allergic Rhinitis Patients with or without Asthma in Batman 成人变应性鼻炎伴或不伴哮喘患者对常见吸入性变应原的致敏性分布

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Astim Allerji Immunoloji Pub Date : 2022-12-07 DOI: 10.21911/aai.076

C. Tuzer

引用次数: 0

Pneumococcal Vaccination is a Challenge of Pediatric Allergists 肺炎球菌疫苗接种是儿科变态反应学家面临的挑战

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Astim Allerji Immunoloji Pub Date : 2022-12-07 DOI: 10.21911/aai.011

Sinem Polat Terece, H. I. Ertoy Karagol, A. Bakirtas

{"title":"Pneumococcal Vaccination is a Challenge of Pediatric Allergists","authors":"Sinem Polat Terece, H. I. Ertoy Karagol, A. Bakirtas","doi":"10.21911/aai.011","DOIUrl":"https://doi.org/10.21911/aai.011","url":null,"abstract":"Objective: An increased risk of invasive pneumococcal disease (IPD) has been reported in children with asthma before the introduction of pneumococcal vaccines (PVs). However, the evidence is limited after PV entered the routine immunization schedule. We aimed to investigate whether pediatric allergists recommend additional PV (aPV) to asthmatic children and if so whether there are any asthma-specific risk factors they consider. We also wanted to determine any changes in their recommendations during the COVID-19 pandemic. Materials and Methods: A questionnaire was e-mailed to all members of the Academy of Pediatric Allergy and Asthma in Turkey. The questionnaire was filled online and consisted of 14 questions. Results: The questionnaire was e-mailed to 220 members. The response rate was 56.3% and 60.5% of PA recommended aPV. The most frequent asthma specific factors for aPV were severe asthma (70.2%), long term oral corticosteroid use (65.3%) and frequent exacerbations / hospitalizations (62.9%). COVID-19 pandemic increased the rate of questions asked to PA about aPV for asthmatic children compared to previous periods (75.8 vs 33.9%) (p<0.001) and %27 of PA changed their recommendations in favor of aPV during pandemic.Conclusion: Asthmatic children is not infrequent. Severe asthma and related factors seem to be the leading reasons to recommend aPV for asthmatic children. The aPV recommendation by PA is increased during COVID-19 pandemic.","PeriodicalId":42004,"journal":{"name":"Astim Allerji Immunoloji","volume":null,"pages":null},"PeriodicalIF":0.2,"publicationDate":"2022-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41430175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship of Fatty Acid Binding Protein 4 with Asthma and Severity of Asthma 脂肪酸结合蛋白4与哮喘及哮喘严重程度的关系

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Astim Allerji Immunoloji Pub Date : 2022-12-07 DOI: 10.21911/aai.021

S. Demir, Derya Unal, D. Sonmez, O. Ozdemir, B. Berçik İnal

引用次数: 0

A Patient Presenting with Chronic Mucocutaneous Candidiasis: A Novel IL12RB1 Mutation 一例慢性粘膜皮肤念珠菌感染患者：一个新的IL12RB1突变

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Astim Allerji Immunoloji Pub Date : 2022-12-07 DOI: 10.21911/aai.014

S. Esenboğa, Hacer Neslihan Bildik, M. Ocak, D. Çağdaş, I. Tezcan

引用次数: 0