Journal of Marine Medical Society最新文献

{"title":"A Successfully Managed Case of Progressive Respiratory Failure Due to Ruptured Pulmonary Hydatid Cyst","authors":"V. Shrinath, Srishti Tripati, Kislay Kishore, Rahul Tyagi, I. M. Pandey","doi":"10.4103/jmms.jmms_97_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_97_23","url":null,"abstract":"","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"20 1","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139257281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Millets as Nature’s Nutraceuticals: Time to Restitute with Attentiveness","authors":"Sumeet Singh, Anuj Singhal, Supreet Kaur Kalra, A. Yadav, Anupam Kumar","doi":"10.4103/jmms.jmms_100_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_100_23","url":null,"abstract":"","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"16 5","pages":""},"PeriodicalIF":0.3,"publicationDate":"2023-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139257622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"T-regulatory Cells in Acute Leukemia and their Relation with Induction Outcome","authors":"Arunima Gupta, Venkatesan Somasundaram, Preeti Tripathi, Janmeet Kular, Kanwal Jeet Singh, Jasvinder Kaur Bhatia","doi":"10.4103/jmms.jmms_41_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_41_23","url":null,"abstract":"Abstract Background: The leukemic microenvironment has become an area of interest for researchers in recent times. Nonmalignant T and B lymphocytes form a significant part of leukemic microenvironment and are postulated to have an effect on its progression and behavior. These lymphocytes are constantly interacting with blasts and are actively involved in innate and acquired immune responses against these blasts. We decided to look at the role of T-regulatory lymphocytes in tumor surveillance and treatment outcome. Aim and Objectives: The aims and objectives of the study are to evaluate the role of T-regulatory lymphocytes in acute leukemia cases and its correlation with treatment outcome. Materials and Methods: We evaluated consecutive 55 acute leukemia cases to investigate the prognostic effect of T-regulatory cells (T-regs) in acute leukemia. The study period was between January 2021 and December 2021. All patients whose complete records were available till the completion of induction were included in the study. The immunophenotype used to characterize and evaluate T-regs was CD4 + CD25 + T lymphocytes. For comparison, a total of 10 healthy controls were included in the study. Clinicohematological parameters including fever, lymphadenopathy, hepatosplenomegaly, extramedullary involvement, day 1 total leukocyte count, and blast percentage in peripheral blood and bone marrow were studied and documented to establish any possible correlation with T-regs percentage and treatment outcome. The treatment outcome evaluated in the study was complete remission postfirst induction. Results: As compared to those of healthy participants, the frequencies of CD4 + CD25 + T-regs in the peripheral blood of acute leukemia patients were significantly increased (1.5% [range: 0.50%–4.3%] vs. 0.58% [range: 0.40%–1.05%], P = 0.0001). Furthermore, the frequencies of CD4 + CD25 + T-regs in the peripheral blood of acute leukemia patients who did not achieve remission were significantly increased as compared to those who achieved remission (2.9% [range: 0.20%–4.3%] vs. 1.3% [range: 0.30%–2.9%], P = 0.002). No significant correlation was noted in the T-reg cells and parameters such as fever, lymphadenopathy, hepatosplenomegaly, extramedullary involvement, day 1 total leukocyte count, and blast percentage. Conclusion: This study suggests the possibility of using T-regs percentages as a prognostic indicator of acute leukemia and possible role of anti-T-regulatory immunomodulators in improving the outcome of disease.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":" 13","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135190960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changing Trends in the Clinical Suspicion of Scrub Typhus in Acute Febrile Illness Patients","authors":"Rajat Shukla, Ajay Kumar, Col Amit Katya, K. K. Kompella, Somali Pattanayak, Anand Menon, M. Sasikanth","doi":"10.4103/jmms.jmms_10_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_10_23","url":null,"abstract":"Abstract Introduction: Scrub typhus is an important and widespread cause of acute febrile illness (AFI), which can be diagnosed easily by serological assay. Methods: All cases of AFI were sent for Scrub Typhus serology by rapid Enzyme Linked Immuno-Sorbent Assay (ELISA) method. Anyone found positive was admitted for further evaluation. Results: In this series 80 % had liver abnormality, 80 % had ARDS, 40 % had renal failure, 40 % had eschar and 80 % of them had MODS. Only 20 % had clinical features of encephalitis with MRI brain haemorrhagic transformation of infarct. All patients responded well to treatment with Doxycycline with hospitalization of around 7-10 days. Conclusion: This case series highlights the importance of keeping a high index of clinical suspicion to exclude scrub typhus in all AFI patients.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":" 72","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135191782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the COVID-19 Lockdown on Medical Education: A Cross-sectional Study","authors":"T. S. Santosh, Priyadarshee Patra, Priyank Singh Mehta","doi":"10.4103/jmms.jmms_39_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_39_23","url":null,"abstract":"Abstract Introduction: The Corona virus disease (COVID-19) pandemic had a drastic effect on medical education. It led to the closure of teaching establishments, hostels, and medical institutions, as well as displacement from both clinical rotations and their medical school campuses. Medical curriculum was restructured and for some time education was purely virtual. This study aimed to find out the perceived impact of the COVID 19 lockdown on medical education for final year undergraduate medical students. Methods: This cross sectional study was carried out at a government medical college in Mumbai. It included 142 undergraduate medical students studying in the final year of MBBS. The data were collected with the help of an online questionnaire on Google Forms. The questionnaire had an inbuilt consent form that was not mandatory for the students. The questionnaire would terminate if the respondent did not agree to give consent. Results: Our results showed that 36.6% felt that the medical curriculum was to be revised to include more virtual classes, whereas 93.6% said that they were concerned about the loss of clinical and practical experience due to lockdown. About 90% were concerned about how examinations would be affected. 29.6% also wished that they would have rather chosen an alternate professional course or stream due to their perceived stressful lives. Discussion: This present study highlighted the increased academic concerns among final year medical students during the COVID 19 pandemic. Medical schools globally should recognize the need and put systems in place to promote the well being of the future workforce with a pandemic preparedness plan.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":" 6","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135191920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects on Pulmonary Functions in Patients Undergoing Hyperbaric Oxygen Therapy: A Prospective Observational Study","authors":"Rahul Tyagi, C. S. Mohanty, G. S. Chowdhary, Rajeev Deo, H. B. S. Chaudhry, Durgesh Kumar Chaudhary","doi":"10.4103/jmms.jmms_46_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_46_23","url":null,"abstract":"Abstract Introduction: Hyperbaric Oxygen Therapy (HBOT) consists of administering oxygen at pressures higher than atmospheric pressure. Though HBOT remains one of the safest therapies used today, it is not completely devoid of side effects. Pulmonary oxygen toxicity can result as a result of continuous exposure of elevated levels of oxygen for increased duration and at increased pressures. The main pathological manifestations occur as acute exudative phase followed by subacute proliferative phase. Effects of HBOT on pulmonary functions has not been studied in detail. This study was conducted to ascertain the effects of HBOT on pulmonary functions and determine if these changes are reversible in nature. Material and Method: A prospective observational study was conducted at a tertiary care hospital over a period of 02 years. A total of 72 patients who were undergoing HBOT for any indication normal chest radiograph and normal spirometry/DLCO were included in the study. Spirometry and DLCO was done initially at the time of inclusion and repeated after half of the total planned HBOT sessions and finally at the end of all sessions of HBOT. Spirometry and DLCO was also repeated 6 months post completion of HBOT. The HBOT protocol consisted of breathing 100% oxygen at 2.4 atmospheric absolute (ATA) for 90 minutes which was referred as one session. Total sessions varied from 20-30 based on indication and response of their primary disease to HBO. Results: The mean age score in study population was 47.12 ± 12.88. Among the study population, 12(24%) participants were male and 38(76%) participants were female. The mean BMI was 24.49 ± 5.45. The mean DLCO was 6.67 ± 1.45 ml/min/mm Hg pre intervention, it was 6.38 ± 1.43 ml/min/mm Hg at mid cycle and 6.21 ± 1.41 ml/min/mm Hg post intervention and at 6 months follow up it was 6.43 ± 1.46 ml/min/mm Hg. The difference in the DLCO at mid cycle, post intervention and 6 months follow up period with baseline value were statistically significant (P value <0.05). The mean FVC was 2.59 ± 0.59 L pre intervention, 2.41 ± 0.6 L at mid cycle, 2.22 ± 0.53 L immediately post intervention and 2.44 ± 0.59 L at 6 months follow up. The difference in the FVC score at mid cycle, post intervention and 6 months follow up with baseline value were statistically significant (P value <0.001). The mean FEV1 was 2.15 ± 0.52L pre- intervention, 2.14 ± 1.97L at mid cycle, 2.03 ± 0.53 L post intervention and 2.52 ± 2.02 L at 6 months follow up. The difference in the FEV1 score at post intervention with baseline value (pre-intervention) was statistically significant (P value <0.001). However, the difference in the FEV1 score at 6 months follow up period with baseline value (pre-intervention) was not statistically significant (P value >0.005). Conclusion: HBOT although a safe intervention, it is not totally devoid of complications. Although our study did reveal statistically significant changes in pulmonary function in most of the instances, it ","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":" 10","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135191917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of endoscopic septoplasty outcomes using nasal obstruction symptom evaluation scale","authors":"Tgs Basappa Varun, A. Dutta, Rahul Naga, D. Gupta, S. Mathews","doi":"10.4103/jmms.jmms_1_23","DOIUrl":"https://doi.org/10.4103/jmms.jmms_1_23","url":null,"abstract":"Inroduction: Nasal obstruction is the most common complaint in an average ENT practice, and a deviated nasal septum is the most common cause of nasal obstruction. The deformities of the septum are usually congenital, developmental, traumatic, or iatrogenic in nature with traumatic and iatrogenic being the most common. The aim of the study was to evaluate patient-based outcomes on subjective-based opinion in patients undergoing endoscopic septoplasty. Methods: This study was conducted in a tertiary care hospital setting in western Maharashtra. This was a prospective observational study.The present study was conducted on 50 patients who presented with signs and symptoms attributed to septal deviation who underwent endoscopic septoplasty and followed up in the department of otorhinolaryngology, head and neck surgery, tertiary care hospital, Mumbai, Maharashtra.The results of our study were analyzed on SPSS Software using “Paired t-test”. Results: On the statistical analysis of the Nasal Obstruction Symptom Evaluation score of patients (n = 50) at baseline and at postoperative 3- and 6-month follow-up, mean + standard deviation was 61.2 ± 11.18, 9.1 ± 5.32, and 8.1 ± 4.51, respectively, with P < 0.0001 preoperative and 3-month postoperative follow-up which is highly significant and P > 0.05 for 3- and 6-month follow-up and hence insignificant. Conclusion: Endoscopic septoplasty results in significant improvement in disease-specific quality of life with high patient satisfaction.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"1 1","pages":"129 - 132"},"PeriodicalIF":0.3,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70803844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Projecting prescribing issues and patient patterns on the way to therapeutic appropriateness at the community level through elderly hypertensives","authors":"Adwait Sodani, Tomalwar Murari, V. Sashindran, A. Menon","doi":"10.4103/jmms.jmms_50_22","DOIUrl":"https://doi.org/10.4103/jmms.jmms_50_22","url":null,"abstract":"Introduction: Despite treatment, up to 50% of older hypertensives have poorly controlled blood pressure in the community. Possibly, the management advice does not reach the intended. Who stands responsible; the prescriber, the system (social dynamics) or the patients themselves? The study aims to showcase various prescribing practices and patient behaviours that influence therapeutic delivery and thus patient care. Appropriate redressals to such practices and behaviours as and when required during health planning/practice could result in the percolation of the best possible care unto all socioeconomic strata within a community. Materials and Methods: Older patients on antihypertensives (n = 143) were interviewed by visits to various urban slums of a district in Western Maharashtra, India, between December 2018 and October 2020 for this cross-sectional, descriptive study. Demographic and clinical data were recorded on a predesigned pro forma with reasons for the patient's behavior concerning disease/treatment. Finally, available prescriptions and the latest blood/urine evaluations were recorded. Prescribing practices were recorded with available tools and data was analysed. Results: The mean age of the study population was 68 ± 7.39 years. Optimal control of the blood pressure was not achieved in 72.03% of patients (P < 0.0001%; 95% confidence interval [CI]: 32.94–53.54%), whereas adverse drug reactions (ADRs) occurred in 35.66% of patients. Physician's prescription was available in 101 patients for prescription quality assessment; however, 12 patients had never been prescribed and 30 lost their prescriptions. Even patients under regular follow-up with a physician failed to achieve the blood pressure targets or prevent an ADR. Finally, the patients' behavior was studied, wherein 41.22% became lost to follow-up and 64.13% of patients had old prescriptions. Forty-two patients could explain such behaviors. Conclusions: Both physicians and patients were responsible for poor blood pressure control. The means of assisting a physician on physician-patient communication would reduce physician workload (thus increasing efficiency) and reduce confusion/misconception (about drug/disease etc) that patient upholds (thus addressing counterproductive patient behaviours).","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"25 1","pages":"18 - 25"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43197945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated maxillary sinus plasmacytoma: A rare entity","authors":"T. Madan, Rahul Naga, M. Akhtar, A. Dutta","doi":"10.4103/jmms.jmms_47_22","DOIUrl":"https://doi.org/10.4103/jmms.jmms_47_22","url":null,"abstract":"Plasmacytoma is a monoclonal plasma B cell malignancy originating in either bone named as solitary plasmacytoma of the bone or in soft tissue labeled as extramedullary plasmacytoma (EMP). Solitary EMP is rare accounting for <1% of all head-and-neck malignancies, occurring primarily in the upper aerodigestive tract and nasal cavity, with nasal septum being the most common site. It accounts for 4% of all nonepithelial sinonasal tumors. EMPs are four times more common in men and affect geriatric age group routinely in the 6th–8th decade of life. It is pertinent to exclude systemic involvement by utilizing a systematic and well-coordinated approach of clinical, laboratory, and radiologic investigations. EMP of the nasal cavity is rare, but it should be considered in the differential diagnosis of nasal cavity masses in all age groups, especially elderly. The present case report describes a patient affected by EMP, in which tumor arose from left maxillary sinus. The patient was managed with endoscopic resection of the mass followed by external beam radiotherapy. The patient was followed up for 2 years with routine endoscopies and 18 fluorodeoxyglucose positron emission tomography with complete resolution of the lesion.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"25 1","pages":"107 - 110"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44940992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dyadic congruence, dyadic coping, and psychopathology: Implications in dyads for patients with acute coronary syndrome","authors":"Romita Mitra, S. Pujam, A. Jayachandra, Prafull Sharma","doi":"10.4103/jmms.jmms_124_22","DOIUrl":"https://doi.org/10.4103/jmms.jmms_124_22","url":null,"abstract":"Introduction: Along with a worldwide growth of individuals diagnosed with coronary heart disease (CHD), the number of adults affected with acute coronary syndrome (ACS) has substantially increased over a period of time. Such negative effects are not only limited to the patient but also extend to the caregiver. With this growing importance of caregiving among dyads, there comes a commensurate need to carefully exploring the impact of the relationship on the mental and possible overall health of both. The aim of this study is to examine the impact of dyadic coping as a mediator in the relationship between dyadic congruence and psychopathology of patient-caregiver dyads with acute coronary syndrome. Materials and Method: The present study was of a cross-sectional design. A total of 216 dyads (108 patients and 108 caregivers) were selected for this study. All the participants were chosen from Base Hospital and SGT Hospital, India. Data was collected through survey which included measures to test dyadic congruence, dyadic coping, depression, anxiety and somatic symptoms. Results: Correlation and mediation analysis was carried out for statistical analysis. Dyadic coping significantly mediated the relationship between dyadic congruence and psychopathology among patients with acute coronary syndrome and their caregivers. Conclusion: The findings of the present study throw a light on the impact of dyadic congruence and dyadic coping on the mental health of both patients with acute coronary syndrome and their caregivers.","PeriodicalId":41773,"journal":{"name":"Journal of Marine Medical Society","volume":"25 1","pages":"47 - 54"},"PeriodicalIF":0.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48085416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}