Minerva Pneumologica最新文献_第3页

Asthma, asthma-COPD overlap syndrome, and chronic obstructive pulmonary disease in Turkey 土耳其的哮喘、哮喘-慢性阻塞性肺病重叠综合征和慢性阻塞性肺病

IF 2.5

Minerva Pneumologica Pub Date : 2018-10-01 DOI: 10.23736/S0026-4954.18.01821-7

D. Zorlu, A. Dirican, H. Bayiz, T. Uzar, Nazlı Topbaşı, S. Ozkaya

引用次数: 2

Respiratory management and non-invasive ventilation in patients with amyotrophic lateral sclerosis 肌萎缩侧索硬化症患者的呼吸管理和无创通气

IF 2.5

Minerva Pneumologica Pub Date : 2018-10-01 DOI: 10.23736/S0026-4954.18.01820-5

T. Bregant, L. Leonardis

引用次数: 0

An unusual early onset post-intubation tracheal stenosis 插管后不寻常的早发性气管狭窄

IF 2.5

Minerva Pneumologica Pub Date : 2018-10-01 DOI: 10.23736/S0026-4954.18.01825-4

S. Scarlata, Chiara Rivera, M. Carassiti, F. Agrò, V. Denaro, R. Incalzi

引用次数: 0

Role of diabetes in community acquired pneumonia 糖尿病在社区获得性肺炎中的作用

IF 2.5

Minerva Pneumologica Pub Date : 2018-10-01 DOI: 10.23736/S0026-4954.18.01826-6

F. Gavelli, F. Patrucco

引用次数: 2

Helicobacter pylori and respiratory diseases: update for pneumologist 幽门螺杆菌和呼吸系统疾病:为肺病学家更新

IF 2.5

Minerva Pneumologica Pub Date : 2018-10-01 DOI: 10.23736/S0026-4954.18.01824-2

F. Patrucco, L. Venezia, F. Gavelli, P. Solidoro

引用次数: 12

Inhalation toxicity with N, N′-dimethyl-4,4′-bipyridinium dichloride and changes in spirometry indices N, N ' -二甲基-4,4 ' -二氯化联吡啶的吸入毒性及肺量测定指标的变化

IF 2.5

Minerva Pneumologica Pub Date : 2018-10-01 DOI: 10.23736/S0026-4954.18.01822-9

Arman Shahriary, Mahsa Soleymani, A. Roumi, H. Dana, F. Jamshidi

引用次数: 0

Sleep and circadian dysfunction in neurodegenerative disorders: insights from a mouse model of Huntington's disease. 神经退行性疾病中的睡眠和昼夜节律障碍:来自亨廷顿氏病小鼠模型的见解。

IF 2.5

Minerva Pneumologica Pub Date : 2012-09-01

Dika Kuljis, Analyne M Schroeder, Takashi Kudo, Dawn H Loh, David L Willison, Christopher S Colwell

{"title":"Sleep and circadian dysfunction in neurodegenerative disorders: insights from a mouse model of Huntington's disease.","authors":"Dika Kuljis, Analyne M Schroeder, Takashi Kudo, Dawn H Loh, David L Willison, Christopher S Colwell","doi":"","DOIUrl":"","url":null,"abstract":"Sleep disorders are common in patients with neurogenerative diseases and manifest early in the disease process. Among a number of possible mechanisms underlying the sleep disturbances, there is evidence that dysfunction in the circadian system is a contributing factor. Focusing on a mouse model of Huntington's disease has enabled us to determine that at the onset of symptoms, spontaneous electrical activity of neurons within the central clock is disrupted even though the molecular clockwork is still functional. These findings suggest that the fundamental deficit contributing to disordered sleep is reduced SCN output. The mechanism underlying this deficit is not yet known, but mitochondrial dysfunction and oxidative stress are likely involved. Disruption of circadian output from the SCN would be expected to have wide ranging impact on the body including SCN regulated brain regions and the heart. In fact, there is a great deal of overlap in the non-motor symptoms experienced by HD patients and the consequences of circadian disruption. This raises the possibility that the disordered sleep and circadian function experienced by HD patients may be an integral part of the disease. Furthermore, we speculate that circadian dysfunction may accelerate the pathology underlying HD. If these hypotheses are correct, we should focus on treating circadian misalignment and sleep disruptions early in disease progression.","PeriodicalId":41715,"journal":{"name":"Minerva Pneumologica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2012-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655901/pdf/nihms-464229.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"31534182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sleep and Epilepsy: Strange Bedfellows No More. 睡眠和癫痫:不再是奇怪的同床异梦。

IF 2.5

Minerva Pneumologica Pub Date : 2011-09-01

Erik K St Louis

{"title":"Sleep and Epilepsy: Strange Bedfellows No More.","authors":"Erik K St Louis","doi":"","DOIUrl":"","url":null,"abstract":"Ancient philosophers and theologians believed that altered consciousness freed the mind to prophesy the future, equating sleep with seizures. Only recently has the bidirectional influences of epilepsy and sleep upon one another received more substantive analysis. This article reviews the complex and increasingly recognized interrelationships between sleep and epilepsy. NREM sleep differentially activates interictal epileptiform discharges during slow wave (N3) sleep, while ictal seizure events occur more frequently during light NREM stages N1 and N2. The most commonly encountered types of sleep-related epilepsies (those with preferential occurrence during sleep or following arousal) include frontal and temporal lobe partial epilepsies in adults, and benign epilepsy of childhood with centrotemporal spikes (benign rolandic epilepsy) and juvenile myoclonic epilepsy in children and adolescents. Comorbid sleep disorders are frequent in patients with epilepsy, particularly obstructive sleep apnea in refractory epilepsy patients which may aggravate seizure burden, while treatment with nasal continuous positive airway pressure often improves seizure frequency. Distinguishing nocturnal events such as NREM parasomnias (confusional arousals, sleep walking, and night terrors), REM parasomnias including REM sleep behavior disorder, and nocturnal seizures if frequently difficult and benefits from careful history taking and video-EEG-polysomnography in selected cases. Differentiating nocturnal seizures from primary sleep disorders is essential for determining appropriate therapy, and recognizing co-existent sleep disorders in patients with epilepsy may improve their seizure burden and quality of life.","PeriodicalId":41715,"journal":{"name":"Minerva Pneumologica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2011-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3608109/pdf/nihms351494.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40234603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obstructive sleep apnea and cardiovascular disease: evidence and underlying mechanisms. 阻塞性睡眠呼吸暂停与心血管疾病：证据与内在机制。

IF 2.5

Minerva Pneumologica Pub Date : 2009-12-01

G Jean-Louis, F Zizi, Db Brown, G Ogedegbe, Js Borer, Si McFarlane

{"title":"Obstructive sleep apnea and cardiovascular disease: evidence and underlying mechanisms.","authors":"G Jean-Louis, F Zizi, Db Brown, G Ogedegbe, Js Borer, Si McFarlane","doi":"","DOIUrl":"","url":null,"abstract":"A body of epidemiologic and clinical evidence dating back to the early 1960s establishes the relationships between sleep apnea and cardiovascular disease (CVD). Individuals with obstructive sleep apnea, the most common type of sleep-disordered breathing, are at increased risk for coronary artery disease, congestive heart failure, and stroke. Evidence that treatment of sleep apnea with continuous positive airway pressure reduces blood pressure, improves left ventricular systolic function, and diminishes platelet activation further supports linkage between obstructive sleep apnea and CVD. Notwithstanding, complex associations between these two conditions remain largely unexplained due to dearth of systematic experimental studies. Arguably, several intermediary mechanisms including sustained sympathetic activation, intrathoracic pressure changes, and oxidative stress might be involved. Other abnormalities such as dysfunctions in coagulation factors, endothelial damage, platelet activation, and increased systemic inflammation might also play a fundamental role. This review examines evidence for the associations between obstructive sleep apnea and CVD and suggested underlying anatomical and physiological mechanisms. Specific issues pertaining to definition, prevalence, diagnosis, and treatment of sleep apnea are also discussed. Consistent with rising interest in the potential role of the metabolic syndrome, this review explores the hypothesized mediating effects of each of the components of the metabolic syndrome.","PeriodicalId":41715,"journal":{"name":"Minerva Pneumologica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2009-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106988/pdf/nihms248040.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30217250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility of individualized aerobic threshold-based exercise on ventilatory efficiency in sedentary adult asthma patients 个体化有氧阈值运动对久坐成人哮喘患者通气效率的可行性

IF 2.5

Minerva Pneumologica Pub Date : 1900-01-01 DOI: 10.23736/S0026-4954.18.01829-1

Ratko Peric, F. Drobnic, J. Baker

引用次数: 2