Senior Care Pharmacist最新文献_第2页

Dietary Supplement Safety in Older Adults: A Review of Published Case Reports. 老年人膳食补充剂的安全性：对已发表病例报告的回顾。

Senior Care Pharmacist Pub Date : 2025-01-01 DOI: 10.4140/TCP.n.2025.32

Alex Shahverdian, Mahtab Jafari

{"title":"Dietary Supplement Safety in Older Adults: A Review of Published Case Reports.","authors":"Alex Shahverdian, Mahtab Jafari","doi":"10.4140/TCP.n.2025.32","DOIUrl":"10.4140/TCP.n.2025.32","url":null,"abstract":"Objective: This review summarizes recent case reports where the consumption of dietary supplements by older adults may have caused an adverse event. Data Sources: In December 2023, PubMed was surveyed for case reports published from 2000 onwards, using two medical subject heading (MeSH) terms, \"aged\" and \"dietary supplements,\" where the latter was combined with the MeSH subheadings \"adverse effects,\" \"poisoning,\" or \"toxicity.\" Major clinical trials for dietary supplements were identified at <ext-link ext-link-type=\"uri\" xlink:href=\"https://ClinicalTrials.gov\">ClinicalTrials.gov</ext-link>, an online database of clinical research studies, or in PubMed, and screened for information on adverse effects. Data Synthesis: The described search strategy yielded 820 publications, including 122 case reports, which were then manually screened for relevant and informative case reports involving dietary supplements and people 65 years of age or older. Consequently, 41 publications were selected describing 46 individual case reports. Etiologies of adverse events included interactions of dietary supplements with prescribed medication, ingestion of higher-than-intended or instructed supplement doses, intake of the same supplement from multiple sources, and supplement contamination. Prominent adverse events encompassed hypercalcemia (vitamin D), thyroid test interference (vitamin B7), neuropathy (vitamin B6), oxalate nephropathy (vitamin C), and interactions with warfarin therapy (vitamins E and K, and omega-3 fatty acids). Conclusion: Health care practitioners are advised to consider dietary supplements as contributors to adverse clinical symptom presentations, while patients are encouraged to provide current records of their prescribed medications and dietary supplements to their health care providers. This is particularly important for older adults where both medication intake and supplement consumption are high.","PeriodicalId":41635,"journal":{"name":"Senior Care Pharmacist","volume":"40 1","pages":"32-49"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endings and Beginnings. 结局和开始。

Senior Care Pharmacist Pub Date : 2025-01-01 DOI: 10.4140/TCP.n.2025.1

Chris Alderman

引用次数: 0

Robert J. Miller Research & Education Poster Abstracts: Presented at the ASCP Annual Meeting & Exhibition Gaylord Rockies Resort & Convention Center, Aurora, Colorado November 7-10, 2024. Robert J. Miller研究与教育海报摘要：于2024年11月7日至10日在美国科罗拉多州奥罗拉盖洛德落基山脉度假和会议中心举行的ASCP年会和展览上发表。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.462

引用次数: 0

Ethics and the Development of Professional Identity. 伦理与职业认同的发展。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.438

Jenny Inker

引用次数: 0

Examining the Decline: The Legislative Struggles of the 118th Congress. 审视衰落：第118届国会的立法斗争。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.458

Leigh Davitian

引用次数: 0

Health Care Ethics, 4Ms, and Remembering What Really Matters. 卫生保健伦理，4Ms，记住什么才是真正重要的。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.436

Chris Alderman

引用次数: 0

Examining the impact of Anticholinergic Burden on Hospitalized Older People Receiving Concomitant Cholinesterase inhibitors. 检查抗胆碱能负担对住院老年人同时使用胆碱酯酶抑制剂的影响。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.449

Jiajie Guan, John Noviasky, Jonathan H Watanabe

{"title":"Examining the impact of Anticholinergic Burden on Hospitalized Older People Receiving Concomitant Cholinesterase inhibitors.","authors":"Jiajie Guan, John Noviasky, Jonathan H Watanabe","doi":"10.4140/TCP.n.2024.449","DOIUrl":"10.4140/TCP.n.2024.449","url":null,"abstract":"Background: Cholinesterase (ChE) inhibitors enhance central cholinergic function and are considered as standard treatments to ameliorate symptoms relating to Alzheimer's disease. Though anticholinergic medications directly antagonize the effects of ChE inhibitors, they are commonly prescribed among hospitalized adults. Objective: To determine the impact of high anticholinergic burden (ACB) on length of stay (LOS) and 30-day readmission rates among hospitalized patients receiving concomitant ChE inhibitors. Methods: This was a retrospective cohort study conducted at a tertiary care academic medical center involving hospitalized patients on medical floors who received any Food and Drug Administration-approved ChE inhibitors during their hospital stay from October 1, 2022, to September 30, 2023. The primary outcome of the study was to compare hospital LOS among patients with high (ACB ≥ 3) versus low (ACB < 3) ACB. The secondary outcome was to assess the impact of ACB burden on 30-day readmission rates. Results: Among hospitalized adults, patients with high ACB exposure had a significantly longer hospital LOS (median: 5.50 vs 4.25 days; P < 0.001) than patients with low ACB exposure, after adjusting for covariates. Analysis of secondary outcome revealed that though the high ACB group had a higher 30-day readmission rate compared with the lower ACB group (6.8% vs. 2.2%), the difference was not statistically significant (OR = 3.46, 95% CI 0.85-14.08; P = 0.083). Conclusion: A high ACB exposure among older individuals taking concurrent ChE inhibitors is associated with a longer hospital stay.","PeriodicalId":41635,"journal":{"name":"Senior Care Pharmacist","volume":"39 12","pages":"449-457"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142773302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ethical Geriatric Pharmacy: Combating Ageism and Enhancing Patient Care. 伦理老年药学：打击老年歧视和加强病人护理。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.441

Madeline M Yuzwa

引用次数: 0

Leading Pharmacists Who Experience Patient Loss. 经历病人流失的主要药剂师。

Senior Care Pharmacist Pub Date : 2024-12-01 DOI: 10.4140/TCP.n.2024.445

Marlene Nguyen, Donna M Breese, Kristin Kellett

引用次数: 0

Notes on the Consultant Pharmacist Practice Model: At Home and Abroad. 关于顾问药剂师实践模式的说明：国内外。

Senior Care Pharmacist Pub Date : 2024-11-01 DOI: 10.4140/TCP.n.2024.398

Chad Worz

引用次数: 0