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A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE最新文献

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Unique Transcriptomic and Metabolic Characteristics of Pulmonary Monocytes and Macrophages in an Inflammatory Rat Model of Pulmonary Arterial Hypertension with Bmpr2Mutations bmpr2突变肺动脉高压炎症大鼠模型中肺单核细胞和巨噬细胞独特的转录组学和代谢特征
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180
L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls
{"title":"Unique Transcriptomic and Metabolic Characteristics of Pulmonary Monocytes and Macrophages in an Inflammatory Rat Model of Pulmonary Arterial Hypertension with Bmpr2Mutations","authors":"L. Zhao, C. Cunningham, D. Kim, R. Vihn, E. Schneider, T.-H. Wu, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1180","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115023691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reciprocal Bi-Directional Cross-Talk Between GATA6 and YAP Regulates Vascular Smooth Muscle Cell Hyper-Proliferation in PAH GATA6与YAP双向互扰调控PAH血管平滑肌细胞超增殖
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192
T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova
{"title":"Reciprocal Bi-Directional Cross-Talk Between GATA6 and YAP Regulates Vascular Smooth Muscle Cell Hyper-Proliferation in PAH","authors":"T. Kudryashova, A. Ichihara, T. Toyama, Y. Shen, D. Goncharov, T. Avolio, R. Lafyatis, M. Trojanowska, E. Goncharova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1192","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130491549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Sex Hormones on the Severity of Experimental Pulmonary Hypertension in a Natural Killer Cell-Deficient IL-15 Knockout Rat Model 性激素对自然杀伤细胞缺陷IL-15敲除大鼠实验性肺动脉高压严重程度的影响
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177
L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston
{"title":"Effect of Sex Hormones on the Severity of Experimental Pulmonary Hypertension in a Natural Killer Cell-Deficient IL-15 Knockout Rat Model","authors":"L. Hilton, M. Ratsep, K. Laverty, M. Mitchell, S. Renaud, M. Soares, M. Ormiston","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1177","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122344916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elucidating the Role of Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in Pulmonary Hypertension 髓样细胞1 (TREM-1)触发受体在肺动脉高压中的作用
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176
V. Lin, D.D. Xing, Y. Wu, S. Hardy, P.R. Cochran, E. Helton, S. Pamboukian, J. Joly, J. Tallaj, G. A. Payne, J. Barnes, J. M. Wells
{"title":"Elucidating the Role of Triggering Receptor Expressed on Myeloid Cells-1 (TREM-1) in Pulmonary Hypertension","authors":"V. Lin, D.D. Xing, Y. Wu, S. Hardy, P.R. Cochran, E. Helton, S. Pamboukian, J. Joly, J. Tallaj, G. A. Payne, J. Barnes, J. M. Wells","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1176","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"2015 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129111330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single-Cell RNA-seq Reveals Transcriptionally Convergent Pulmonary Endothelial Cells in an Inflammatory Model of Pulmonary Arterial Hypertension with BMPR2 Dysfunction 单细胞RNA-seq揭示肺动脉高压伴BMPR2功能障碍炎症模型中转录趋同的肺内皮细胞
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178
D. Kim, L. Zhao, T. Wu, R. Vihn, E. Schneider, C. Cunningham, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls
{"title":"Single-Cell RNA-seq Reveals Transcriptionally Convergent Pulmonary Endothelial Cells in an Inflammatory Model of Pulmonary Arterial Hypertension with BMPR2 Dysfunction","authors":"D. Kim, L. Zhao, T. Wu, R. Vihn, E. Schneider, C. Cunningham, A. McQuiston, P. Kao, X. Jiang, A. Tian, M. Nicolls","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1178","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121419908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SIRT7- and JNK-Mediated Akt Supports Glycolysis-Driven Lipogenesis and Proliferation of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension SIRT7-和jnk介导的Akt支持糖酵解驱动的脂肪生成和肺动脉高压人血管平滑肌细胞的增殖
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175
L. Jiang, D. Goncharov, Y. Shen, D. Lin, B. Chang, A. Pena, E. Goncharova, T. Kudryashova
{"title":"SIRT7- and JNK-Mediated Akt Supports Glycolysis-Driven Lipogenesis and Proliferation of Human Pulmonary Arterial Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension","authors":"L. Jiang, D. Goncharov, Y. Shen, D. Lin, B. Chang, A. Pena, E. Goncharova, T. Kudryashova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1175","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129376621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ATAC Seq Reveals That Genes Involved in the Persistently Activated Phenotype of PH Fibroblasts Exhibit Open Enhancers and Promoters That Are Enriched in Binding Sites for Several Transcription Factors ATAC序列揭示了参与PH成纤维细胞持续激活表型的基因表现出开放的增强子和启动子，这些增强子和启动子富集于几种转录因子的结合位点
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179
C. Hu, A. Laux, H. Zhang, K. Stenmark
{"title":"ATAC Seq Reveals That Genes Involved in the Persistently Activated Phenotype of PH Fibroblasts Exhibit Open Enhancers and Promoters That Are Enriched in Binding Sites for Several Transcription Factors","authors":"C. Hu, A. Laux, H. Zhang, K. Stenmark","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1179","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133007689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mitochondrial Dysfunction as a Primary Cause of Impaired Angiogenesis in Pulmonary Arterial Hypertension 线粒体功能障碍是肺动脉高压患者血管生成受损的主要原因
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183
M. Niihori, J. James, N. McCalin, R.C. Philip, R. Rafikov, O. Rafikova
{"title":"Mitochondrial Dysfunction as a Primary Cause of Impaired Angiogenesis in Pulmonary Arterial Hypertension","authors":"M. Niihori, J. James, N. McCalin, R.C. Philip, R. Rafikov, O. Rafikova","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1183","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125558454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lipid Metabolomics Analysis of Pulmonary Veno-Occlusive Disease 肺静脉闭塞性疾病的脂质代谢组学分析
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1189
P. Yuan
{"title":"Lipid Metabolomics Analysis of Pulmonary Veno-Occlusive Disease","authors":"P. Yuan","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1189","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1189","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"213 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132429894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Estrogen Stimulates Angiogenesis and Regulates Metabolism in the Right Ventricle and on Cultured Cardiac Microvascular Endothelial Cells 雌激素在右心室和培养的心脏微血管内皮细胞上刺激血管生成和调节代谢
A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE Pub Date : 2022-05-01 DOI: 10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1186
S. Bousseau, B. Yakubov, E. Sims, M. Repass, A. Frump, T. Lahm
{"title":"Estrogen Stimulates Angiogenesis and Regulates Metabolism in the Right Ventricle and on Cultured Cardiac Microvascular Endothelial Cells","authors":"S. Bousseau, B. Yakubov, E. Sims, M. Repass, A. Frump, T. Lahm","doi":"10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1186","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a1186","url":null,"abstract":"","PeriodicalId":415780,"journal":{"name":"A27. SOMA: SEX, METABOLISM, INFLAMMATION, AND IMMUNITY IN PULMONARY VASCULAR DISEASE","volume":"171 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115670990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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