Ewha Medical Journal最新文献

Psoas-lumbar vertebral index and short-term pain relief after pulsed radiofrequency treatment of the dorsal root ganglion in postherpetic neuralgia in Korea: a retrospective pilot study. 韩国背根神经节脉冲射频治疗带状疱疹后神经痛后腰腰椎指数和短期疼痛缓解：一项回顾性试点研究。

IF 0.9

Ewha Medical Journal Pub Date : 2026-10-20 DOI: 10.12771/emj.2026.01536

Seung Hee Yoo, Eunbi Cho, Won-Joong Kim

{"title":"Psoas-lumbar vertebral index and short-term pain relief after pulsed radiofrequency treatment of the dorsal root ganglion in postherpetic neuralgia in Korea: a retrospective pilot study.","authors":"Seung Hee Yoo, Eunbi Cho, Won-Joong Kim","doi":"10.12771/emj.2026.01536","DOIUrl":"https://doi.org/10.12771/emj.2026.01536","url":null,"abstract":"Purpose: The psoas-lumbar vertebral index (PLVI), a marker of central sarcopenia measured using computed tomography (CT) or magnetic resonance imaging (MRI), has been linked to the development of postherpetic neuralgia (PHN). Whether PLVI predicts short-term pain relief after pulsed radiofrequency (pRF) treatment of the dorsal root ganglion (DRG) in established PHN remains unknown. This pilot study examined the association between PLVI and the reduction in numeric rating scale (NRS) pain scores 1 month after pRF.Methods: Patients with PHN who underwent DRG pRF and had CT or MRI scans available for PLVI measurement were retrospectively reviewed. Correlations of the NRS reduction rate with PLVI and other variables were assessed, with 95% confidence intervals (CIs). Patients were divided into low- and high-PLVI groups using sex-specific medians and compared; multivariable regression was adjusted for sex. A supplementary responder analysis used thresholds of ≥30% and ≥50% reduction.Results: In 19 patients, NRS scores decreased from 4.8±1.7 to 3.2±1.7, with a reduction rate of 29.3%±34.0%. PLVI was not significantly correlated with the reduction rate (r=-0.17; 95% CI, -0.58 to 0.31; P=0.49); neither the reduction rate (P=0.71) nor responder rates differed between the low- and high-PLVI groups. Male sex was associated with a smaller reduction (adjusted B=-47.2 percentage points; 95% CI, -90.9 to -3.5; P=0.036), although the unadjusted group comparison was not significant (Welch P=0.051) and 15 variables were tested without correction for multiple comparisons.Conclusion: This pilot cohort showed no detectable association between PLVI and short-term pain relief after pRF; its small size precludes establishing the absence of an association. The exploratory sex difference warrants investigation in larger prospective studies with comprehensive sarcopenia assessment.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Global, regional, and national burden of motor neuron diseases, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021. 运动神经元疾病的全球、区域和国家负担，1990-2021:2021年全球疾病负担研究的系统分析

IF 0.9

Ewha Medical Journal Pub Date : 2026-10-20 DOI: 10.12771/emj.2026.01480

Jung-Hyun Park, Dong Keon Yon, Min-Seo Kim, Yoonkyung Chang, Somin Park, Jae Il Shin, Tae-Jin Song

{"title":"Global, regional, and national burden of motor neuron diseases, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.","authors":"Jung-Hyun Park, Dong Keon Yon, Min-Seo Kim, Yoonkyung Chang, Somin Park, Jae Il Shin, Tae-Jin Song","doi":"10.12771/emj.2026.01480","DOIUrl":"https://doi.org/10.12771/emj.2026.01480","url":null,"abstract":"Purpose: Healthcare planning and resource allocation require accurate estimates of the burden of motor neuron diseases (MNDs). This study evaluated the global impact of MNDs from 1990 to 2021 as part of the Global Burden of Disease (GBD) Study 2021.Methods: GBD 2021 data were used to assess the global burden of MNDs from 1990 to 2021 in terms of prevalence, incidence, disability-adjusted life years (DALYs), and deaths. The relationship between MND burden and the Socio-demographic Index (SDI) was also examined.Results: Globally, MNDs accounted for 272,732 prevalent cases (95% uncertainty interval [UI], 236,195-313,676), 64,178 incident cases (95% UI, 58,506-70,270), 1,040,566 DALYs (95% UI, 963,064-1,123,956), and 39,082 deaths (95% UI, 35,757-42,433) in 2021. The corresponding age-standardized rates per 100,000 people were 3.31 (95% UI, 2.86-3.80) for prevalence, 0.46 (95% UI, 0.42-0.49) for mortality, and 12.17 (95% UI, 11.24-13.15) for DALYs. From 1990 to 2021, the numbers of prevalent and incident cases increased, but their age-standardized rates decreased by 1.36% and 4.69%, respectively. By contrast, the age-standardized mortality rate increased by 19.84%. MND burden was generally higher in regions with a high SDI, although rates in high-income Asia Pacific were relatively low compared with those in regions with similar SDI values.Conclusion: From 1990 to 2021, the absolute burden of MNDs increased, age-standardized prevalence and incidence rates declined slightly, and mortality-related burden increased. These trends underscore the need for evidence-based national and global healthcare planning. Geographic variation in MND burden may reflect regional differences in the roles of sociodemographic and genetic factors.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The burden of neck pain across US states, 1990-2021: a systematic analysis of Global Burden of Disease Study 2021 data. 1990-2021年美国各州颈部疼痛负担：对2021年全球疾病负担研究数据的系统分析

IF 0.9

Ewha Medical Journal Pub Date : 2026-10-02 DOI: 10.12771/emj.2026.01270

Somin Park, Dong Woo Shin, Jung-Hyun Park, Yoonkyung Chang, Moo-Seok Park, Hyun Kyung Kim, Tae-Jin Song

{"title":"The burden of neck pain across US states, 1990-2021: a systematic analysis of Global Burden of Disease Study 2021 data.","authors":"Somin Park, Dong Woo Shin, Jung-Hyun Park, Yoonkyung Chang, Moo-Seok Park, Hyun Kyung Kim, Tae-Jin Song","doi":"10.12771/emj.2026.01270","DOIUrl":"https://doi.org/10.12771/emj.2026.01270","url":null,"abstract":"Purpose: Neck pain is a leading musculoskeletal cause of disability in the United States. This study aimed to assess temporal, geographic, and demographic disparities in its burden across US states from 1990 to 2021.Methods: Global Burden of Disease 2021 data for all 50 US states and the District of Columbia were analyzed for 1990-2021. Counts and age-standardized rates per 100,000 population for prevalence, incidence, and years lived with disability (YLD) were compared by region, state, sex, age group, and sociodemographic index (SDI) level.Results: In 2021, neck pain accounted for 9,430,000 (95% uncertainty interval [UI], 7,400,000-11,590,000) prevalent cases, 1,900,000 (95% UI, 1,490,000-2,320,000) incident cases, and 920,000 (95% UI, 620,000-1,300,000) YLD, increases of 41.17%, 37.44%, and 38.72%, respectively, from 1990. Although age-standardized incidence increased globally by 1.18% (0.07%-2.39%) over 1990-2021, the United States had small declines in age-standardized incidence (-0.11%; 95% UI, -0.18% to -0.06%), prevalence (-0.20%; 95% UI, -0.32% to -0.10%), and YLD (-1.12%; 95% UI, -2.02% to -0.22%). Neck pain rates were highest in the District of Columbia, Georgia, and Delaware and lowest in North Carolina, Alaska, and Wyoming. The burden peaked at ages 40-49 years and was higher in females. Age-standardized YLD rates for neck pain were significantly positively correlated with the SDI (Spearman's ρ=0.601, P<0.001).Conclusion: The geographic and demographic disparities in neck pain burden across US states indicate a need for targeted interventions.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Irritant contact dermatitis: beyond a diagnosis of exclusion. 刺激性接触性皮炎：超出排除性诊断。

IF 0.9

Ewha Medical Journal Pub Date : 2026-10-02 DOI: 10.12771/emj.2026.01522

Da Yeon Kim, Jin Ju Lee, Hae Young Choi

{"title":"Irritant contact dermatitis: beyond a diagnosis of exclusion.","authors":"Da Yeon Kim, Jin Ju Lee, Hae Young Choi","doi":"10.12771/emj.2026.01522","DOIUrl":"https://doi.org/10.12771/emj.2026.01522","url":null,"abstract":"Irritant contact dermatitis (ICD) is the most common form of contact dermatitis and a leading cause of occupational skin disease, but remains underrecognized relative to allergic contact dermatitis (ACD). Direct chemical or physical injury to the epidermal barrier causes ICD, which can develop in anyone when exposure intensity or duration exceeds the skin's repair capacity. ICD is increasingly understood to involve more than barrier disruption: it is an innate immune-mediated inflammatory disorder involving keratinocyte-derived cytokines, neutrophil recruitment, C-C motif chemokine ligand 2-C-C motif chemokine receptor 2-interleukin-1β signaling, Toll-like receptor 3, and inflammasome activation. Host factors, particularly atopic dermatitis and filaggrin loss-of-function variants, further influence susceptibility. Clinical phenotypes range from acute irritant reactions to chronic cumulative dermatitis, and occupational wet work is a major preventable exposure. Distinguishing ICD from ACD is difficult because their clinical and histopathological features overlap, they may coexist, and ICD-related barrier damage may facilitate subsequent allergic sensitization. Diagnosis therefore requires assessment of exposure history, lesion distribution, symptom quality, and temporal course, with patch testing when ACD is suspected. Molecular biomarker panels and noninvasive imaging or barrier-assessment techniques may improve diagnostic precision, but remain investigational. Management should prioritize identifying and removing irritants, reducing exposure, implementing appropriate protective measures, and restoring the epidermal barrier. Recognizing ICD as a distinct clinical entity, rather than simply a diagnosis of exclusion, is essential for accurate diagnosis and effective management of contact dermatitis in clinical practice.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Language editing in the artificial intelligence era: achieving epistemic integrity: an expanded Korean translation. 人工智能时代的语言编辑：实现认知完整性：一个扩展的韩语翻译。

IF 0.9

Ewha Medical Journal Pub Date : 2026-09-21 DOI: 10.12771/emj.2026.01529

Yunhee Whang, Andrew Dombrowski

引用次数: 0

Role-play in graduate genetic counseling education: a practicum experience in South Korea. 研究生遗传咨询教育中的角色扮演：韩国的实习经验。

IF 0.9

Ewha Medical Journal Pub Date : 2026-09-21 DOI: 10.12771/emj.2026.01452

Su-A Lee, Min Seon Park, Arang Kim, Jungwon Huh

{"title":"Role-play in graduate genetic counseling education: a practicum experience in South Korea.","authors":"Su-A Lee, Min Seon Park, Arang Kim, Jungwon Huh","doi":"10.12771/emj.2026.01452","DOIUrl":"https://doi.org/10.12771/emj.2026.01452","url":null,"abstract":"Purpose: Clinical fieldwork in genetic counseling education is constrained by limited training sites, shortages of clinical supervisors, and administrative burdens. Simulation-based learning, including role-play, has therefore been used to support development of counseling competencies. This study described the development, implementation, operational structure, and feasibility of a role-play-based practicum in a graduate genetic counseling program.Methods: This retrospective descriptive report was based on Genetic Counseling Practicum, a spring 2024 course for 11 third-semester students in a graduate genetic counseling program in South Korea. Twenty-two role-play scenarios were developed, including 11 hereditary cancer cases and 11 pediatric or adult genetic disorder cases. The scenarios simulated pretest and posttest encounters during a 6-week, 2-block practicum. Students alternated between counselor and counselee roles, recorded sessions outside class time, and received domain-guided peer and faculty feedback.Results: The scenarios covered patient ages from infancy to late adulthood and included somatic and germline pathogenic variants, a negative multigene panel result, and chromosomal or epigenetic abnormalities. All 22 planned sessions were completed and recorded as scheduled, and all 11 students completed their assigned sessions. The planned assignment, recording, review, and feedback procedures were completed without documented omissions. Approximately 11 scheduled class hours were devoted to feedback, and no external clinical sites or supervisors were required.Conclusion: This study presents an operationally feasible model for a role-play-based practicum with diverse scenarios in a graduate genetic counseling curriculum. It may serve as a practical reference for programs considering similar simulation-based training.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous retrobulbar hematoma on serial computed tomography and magnetic resonance imaging: a case report. 自发性球后血肿的连续计算机断层扫描和磁共振成像：1例报告。

IF 0.9

Ewha Medical Journal Pub Date : 2026-09-21 DOI: 10.12771/emj.2026.01501

Ra Gyoung Yoon, Bo Eun Lee

引用次数: 0

Korean Standard Series allergens and emerging sources: a narrative review. 韩国标准系列过敏原和新出现的来源：叙述回顾。

IF 0.9

Ewha Medical Journal Pub Date : 2026-09-21 DOI: 10.12771/emj.2026.01515

Jeewoo Choi, Hae Young Choi

{"title":"Korean Standard Series allergens and emerging sources: a narrative review.","authors":"Jeewoo Choi, Hae Young Choi","doi":"10.12771/emj.2026.01515","DOIUrl":"https://doi.org/10.12771/emj.2026.01515","url":null,"abstract":"Purpose: This study aimed to address gaps in Korean Standard Series (KSS) information, highlight allergens with increasing patch test positivity, describe potential sources encountered in daily life, and provide guidance on selecting allergen-free alternatives.Methods: Relevant information was identified from KSS patient instruction sheets (Chemotechnique, Sweden), T.R.U.E. TEST patient instruction sheets (SmartPractice, United States), the Contact Dermatitis Institute allergen database, the American Contact Dermatitis Society allergen information sheets, and searches of the PubMed database. English-language review articles, case series, and case reports identified using keywords related to the 25 KSS allergens were selected.Results: Information was updated for the following allergens: nickel, cobalt, potassium dichromate, balsam of Peru, paraben mix, N-isopropyl-N'-phenyl-p-phenylenediamine, formaldehyde, p-tert-butylphenol formaldehyde resin, methylchloroisothiazolinone/methylisothiazolinone, colophonium, imidazolidinyl urea, and 2-mercaptobenzothiazole. Emerging sources included electronic devices, personal protective equipment, including masks whose use increased during the COVID-19 (coronavirus disease 2019) pandemic, nail products, and children's toy slime. In addition, occupational allergen information sheets were developed for hairdressers, healthcare workers, dentists, dental hygienists, and cooks. The Korean-language allergen sheets are provided in the Supplementary Materials.Conclusion: Because the KSS has not been revised for more than 2 decades, emerging allergen sources may be inadequately represented in the existing patient information. Accordingly, updated patient instruction sheets were developed to improve patient understanding and facilitate the practical application of patch test results.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149018084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In this issue: July 2026. 本期：2026年7月。

IF 0.9

Ewha Medical Journal Pub Date : 2026-07-22 DOI: 10.12771/emj.2026.01508

Ji Yeon Byun

引用次数: 0

Metastatic appendiceal mucinous adenocarcinoma presenting as bilateral ovarian masses mimicking advanced ovarian cancer: a case report. 转移性阑尾黏液腺癌表现为双侧卵巢肿块，类似晚期卵巢癌：1例报告。

IF 0.9

Ewha Medical Journal Pub Date : 2026-07-01 Epub Date: 2026-06-22 DOI: 10.12771/emj.2026.01347

Naina Kumar, Gunvanti Rathod, Annapurna Srirambhatla, Mishu Mangla, Nireesha Bukke, Pooja Tejappa Rathod

{"title":"Metastatic appendiceal mucinous adenocarcinoma presenting as bilateral ovarian masses mimicking advanced ovarian cancer: a case report.","authors":"Naina Kumar, Gunvanti Rathod, Annapurna Srirambhatla, Mishu Mangla, Nireesha Bukke, Pooja Tejappa Rathod","doi":"10.12771/emj.2026.01347","DOIUrl":"10.12771/emj.2026.01347","url":null,"abstract":"Appendiceal mucinous adenocarcinoma is a rare gastrointestinal malignancy that may metastasize to the ovaries and closely mimic advanced primary ovarian cancer, creating diagnostic and therapeutic challenges. A 61-year-old postmenopausal woman presented with postmenopausal bleeding, abdominal distension, abdominal pain, and weight loss. Imaging demonstrated bilateral adnexal masses with omental caking and ascites, suggestive of advanced ovarian malignancy. Cancer antigen 125 was elevated, and carcinoembryonic antigen (CEA) levels were markedly increased. She had a history of acute appendicitis 1 year earlier. Biopsy revealed mucinous adenocarcinoma with signet-ring cells. Endoscopic evaluation was unremarkable. Despite neoadjuvant chemotherapy for presumed ovarian cancer, the disease progressed, necessitating cytoreductive surgery. Histopathological examination demonstrated bilateral mucinous adenocarcinoma with peritoneal spread. Immunohistochemistry showed positivity for cytokeratin 20, caudal-type homeobox 2, and special AT-rich sequence-binding protein 2 and negativity for cytokeratin 7 and paired-box gene 8, supporting an appendiceal origin. She was started on fluorouracil, leucovorin, and oxaliplatin chemotherapy. Metastatic appendiceal carcinoma can closely resemble primary ovarian malignancy. Bilateral mucinous ovarian tumors with elevated CEA levels and poor chemotherapy response should prompt evaluation for a gastrointestinal primary tumor.","PeriodicalId":41392,"journal":{"name":"Ewha Medical Journal","volume":" ","pages":"e22"},"PeriodicalIF":0.9,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13473976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148309733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0