Vestnik SurGU. Meditsina最新文献

ATOPIC DERMATITIS. FEATURES OF PATHOGENESIS, CLINICAL IMAGE AND DIAGNOSIS 特应性皮炎。发病机制、临床表现及诊断特点

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-8-13

А. С. Березина, Ю. В. Карачева, Ю. Ю. Винник, С. С. Тактаракова

引用次数: 0

RISK FACTORS OF DRUG LOAD INCREASE FOR PEDIATRIC PATIENTS WITH BRONCHIAL ASTHMA (TEN-YEAR PROSPECTIVE MONITORING RESULTS) 小儿支气管哮喘患者药物负荷增加的危险因素分析(10年前瞻性监测结果)

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-45-51

А. В. Камаев, Ю. Л. Мизерницкий, О. В. Трусова, Наталия Леонидовна Шапорова

{"title":"RISK FACTORS OF DRUG LOAD INCREASE FOR PEDIATRIC PATIENTS WITH BRONCHIAL ASTHMA (TEN-YEAR PROSPECTIVE MONITORING RESULTS)","authors":"А. В. Камаев, Ю. Л. Мизерницкий, О. В. Трусова, Наталия Леонидовна Шапорова","doi":"10.35266/2304-9448-2023-2-45-51","DOIUrl":"https://doi.org/10.35266/2304-9448-2023-2-45-51","url":null,"abstract":"The study aims to determine the anamnestic, functional, and laboratory factors affecting the load of basic drug therapy in children with bronchial asthma during a ten-year regular dynamic monitoring of their height, body weight, spirometry data, the nature of the ongoing treatment of asthma, and the drug doses. An open, prospective monitoring trial included 131 patients, each of whom attended a hospital at least 20 times every 6 months. The data obtained was not used to correct the therapy method and regular medical check-up. By the end of the tenth year, 98 patients had demonstrated the following results: 57.1 % of children maintained a stable load of basic therapy, while the load of drug therapy was increased in 24.5 % of patients, and decreased in 18.4 % of them. The likelihood of a drug load reduction was statistically significantly reduced in patients with a body mass index greater than 90 weight percentile for 18 months or longer in comparison with patients who had never been overweight. Patients with the obstructive disorders detected with spirometry during two or more consecutive visits had a statistically significantly higher risk of drug therapy overload or a lower likelihood of its reduction in comparison with those without any external respiration malfunctions. The allergen-specific therapy made it possible to significantly lower the risk of drug overload and increase the possibility of its reduction. The allergen-specific immunotherapy, body weight management, and absence of obstructive disorders in spirometry all contribute to reducing the drug therapy load while maintaining a controlled course of the disease.","PeriodicalId":413800,"journal":{"name":"Vestnik SurGU. Meditsina","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115368391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GENETIC MARKERS OF PSYCHOLOGICAL WELL-BEING OF ARCTIC ZONE MILITARY PERSONNEL 北极地区军事人员心理健康的遗传标记

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-68-78

А. В. Лемещенко, О. И. Гурина, В. В. Деменева, Н. А. Довгая

{"title":"GENETIC MARKERS OF PSYCHOLOGICAL WELL-BEING OF ARCTIC ZONE MILITARY PERSONNEL","authors":"А. В. Лемещенко, О. И. Гурина, В. В. Деменева, Н. А. Довгая","doi":"10.35266/2304-9448-2023-2-68-78","DOIUrl":"https://doi.org/10.35266/2304-9448-2023-2-68-78","url":null,"abstract":"The study aims to determine features of the emotional state, to assess the severity of depression and anxiety symptoms in military personnel who undergo military service under extreme climate conditions, to detect the association between gene polymorphisms, and to identify their most favorable combination. The L. A. Kurgansky and T. A. Nemchin method was used to assess the stress level; the hospital anxiety and depression scale was used to assess the level of anxiety and depression; the level of personality neuroticism was assessed with the express diagnosis scale developed by the staff at the V. M. Bekhterev State Medical Research Center of Psychiatry and Neurology. Real-time genotyping of servicemen’s genome DNA samples was carried out on a DTprime amplifier. One-way analysis of variance assessed the significance of differences in mean values of qualitative indicators with a normal distribution between three independent groups. The Kraskel-Wallis test assessed variables, whose distribution differed from normal. The assessment of independent factors affecting dependent binary groups was conducted with logistic regression. With more than two groups, assessment was conducted with polynomial logistic regression. The results are demonstrated as a relation of chances with a 95 % confidence interval. Poisson regression was used for discrete variables, with results demonstrated as a related risk with a 95 % confidence interval. The method of psychological and psychiatric screening allowed determining the prevalence of an average level of emotional well-being of military personnel who undergo military service in Arctic zone, as well as their genotypes suitable for such service: genotype T/T of the ACTN3 gene (rs1815739), genotype C/C of the HIF1A gene (rs11549465), genotype T/T of the LIPC gene (rs1532085), and genotype G/G of the BDNF gene (rs6265).","PeriodicalId":413800,"journal":{"name":"Vestnik SurGU. Meditsina","volume":"143 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114139387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RISK FACTORS FOR AND FEATURES OF MULTIPLE AND SINGLETON PREGNANCY COURSE AND OUTCOMES IN PATIENTS WITH EARLY PREECLAMPSIA 早期子痫前期患者多胎和单胎妊娠过程和结局的危险因素和特点

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-34-44

И. А. Кудринских, Л. Д. Белоцерковцева, И. И. Мордовина

引用次数: 0

ISSUES OF SELECTING A PHYSICAL THERAPY TECHNOLOGY IN ACUTE CEREBRAL CIRCULATION DISORDER IN PATIENTS WITH COMORBIDITIES AT THE FIRST REHABILITATION STAGE 急性脑循环障碍伴合并症患者第一康复期物理治疗技术选择问题

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-19-25

Е. А. Скробова, О. Л. Арямкина

引用次数: 0

INFLUENCE OF ANESTHESIA TYPE ON THE BLOOD CIRCULATION IN RATS 麻醉方式对大鼠血液循环的影响

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-79-86

А. Ю. Дубенский, И. А. Рыжков, К. Н. Лапин, З. И. Цоколаева, С. Н. Калабушев, Л. А. Варнакова, В. Т. Долгих, А. В. Гречко

{"title":"INFLUENCE OF ANESTHESIA TYPE ON THE BLOOD CIRCULATION IN RATS","authors":"А. Ю. Дубенский, И. А. Рыжков, К. Н. Лапин, З. И. Цоколаева, С. Н. Калабушев, Л. А. Варнакова, В. Т. Долгих, А. В. Гречко","doi":"10.35266/2304-9448-2023-2-79-86","DOIUrl":"https://doi.org/10.35266/2304-9448-2023-2-79-86","url":null,"abstract":"The study aims to detect the effects of non-inhaled anesthetics of two different types on the parameters of the central hemodynamics and microcirculation in an occlusive reactive hyperemia test in two groups of male Wistar rats weighting 400–500 g. The “ChH” group received 6 % chloral hydrate solution at a dose of 300 mg/kg intraperitoneally, while the “zol + xyl” group received 20 mg/kg of tiletamine/zolazepam (Zoletil 100, France) mixed with 5 mg/kg of xylazine (Xylanit, Russia) intraperitoneally. The following parameters were measured: blood pressure, average heart rate, duration of PQ, QRS, and QTc intervals according to the electrocardiography, cutaneous blood flow with laser Doppler flowmetry, arterial blood gas composition and acid-base state. The mean value of perfusion was recorded simultaneously with electrocardiography and blood pressure. The parameters of a post-occlusive reactive hyperemia were analyzed to conduct an occlusive reactive hyperemia test. Blood pressure was statistically significantly lower in “ChH” group than in “zol + xyl” group when analyzing the central hemodynamics parameters. The “ChH” group demonstrated higher maximum asodilation in reactive hyperemia (CVCmax) and time of its achievement (Tmax). Both types of anesthesia demonstrated compensated and subcompensated mixed acidosis and moderate arterial hypoxemia when comparing parameters of arterial blood gas composition and acid-base state in rats.","PeriodicalId":413800,"journal":{"name":"Vestnik SurGU. Meditsina","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133989455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MODERN RADIODIAGNOSIS METHODS OF INTRAARTICULAR FRACTURES 关节内骨折的现代放射诊断方法

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-14-18

Н. В. Емельянова, Р. В. Чумаков, М. А. Гладышев

引用次数: 0

EFFECTS OF TRANSCRANIAL ELECTRICAL THERAPY ON SYSTEMIC INFLAMMATION IN A HIGH-FAT FRUCTOSE DIET 经颅电疗对高脂肪果糖饮食中全身性炎症的影响

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-87-94

Е. А. Чабанец, А. Х. Каде, О. В. Цымбалов, А. И. Трофименко, Г. Г. Ким

{"title":"EFFECTS OF TRANSCRANIAL ELECTRICAL THERAPY ON SYSTEMIC INFLAMMATION IN A HIGH-FAT FRUCTOSE DIET","authors":"Е. А. Чабанец, А. Х. Каде, О. В. Цымбалов, А. И. Трофименко, Г. Г. Ким","doi":"10.35266/2304-9448-2023-2-87-94","DOIUrl":"https://doi.org/10.35266/2304-9448-2023-2-87-94","url":null,"abstract":"The study aims to conduct a transcranial electrical stimulation therapy trial in rats influencing the indicators of systemic inflammation dynamics and the percentage content of visceral adipose tissue in a highfat fructose diet. The study included 180 male outbred rats, which were randomly distributed into three groups: the first group had a standard diet; the second group received the high-fat fructose diet; and the third group received both transcranial electrical stimulation therapy and the high-fat fructose diet. Tumor necrosis factor-α, interleukin-15, and interleukin-19 concentrations were measured in blood serum. The percentage of visceral adipose tissue in relation to body weight was calculated. The percentage content of visceral adipose tissue and serum concentration of tumor necrosis factor-α were lower, and interleukin-19 was higher in rats that received transcranial electrical stimulation with a high-fat fructose diet in comparison to the second group, which did not undergo the stimulation. Interleukin-19 level in the blood serum of rats in the second group grew as the trial progressed, whereas the opposite occurred in the third group. There was an inverse relation between the predictive variables of transcranial electrical stimulation, interleukin-19, and the variable of tumor necrosis factor-α. The data obtained in the experiment may also indicate that interleukin-15 cannot be unequivocally considered as a key factor associated with a decrease in visceral adipose tissue content when introducing a high fructose and animal-based saturated fat diet to rats.","PeriodicalId":413800,"journal":{"name":"Vestnik SurGU. Meditsina","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133338931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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FEATURES OF DEVELOPING A BIOBANK’S DATABASE OF BIOLOGICAL SAMPLES 开发生物样本数据库的特点

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-63-67

М. Ю. Донников, А. В. Морозкина, Л. В. Коваленко, Ф.Ф. Иванов, И. М. Филиппов, А. А. Уколов

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SARS-COV-2 IS A NEW RISK FACTOR FOR PREECLAMPSIA Sars-cov-2是子痫前期的新危险因素

Vestnik SurGU. Meditsina Pub Date : 1900-01-01 DOI: 10.35266/2304-9448-2023-2-26-33

Л. Д. Белоцерковцева, Л. В. Коваленко, Василий Васильевич Панкратов, С. Е. Иванников, И. И. Мордовина, О. В. Козловская, А. М. Шумков, Д. М. Гаджиева

{"title":"SARS-COV-2 IS A NEW RISK FACTOR FOR PREECLAMPSIA","authors":"Л. Д. Белоцерковцева, Л. В. Коваленко, Василий Васильевич Панкратов, С. Е. Иванников, И. И. Мордовина, О. В. Козловская, А. М. Шумков, Д. М. Гаджиева","doi":"10.35266/2304-9448-2023-2-26-33","DOIUrl":"https://doi.org/10.35266/2304-9448-2023-2-26-33","url":null,"abstract":"The study aims to assess the risks for preeclampsia progression in pregnant women with SARS-CoV-2 based on the study obtained in 2021, which included the pregnancy course and outcome of 1 122 women divided into three groups. The groups were as following: 52 pregnant women with positive SARS-CoV-2 and preeclampsia, 302 women with negative SARS-CoV-2 and preeclampsia, and 768 pregnant women with positive SARS-CoV-2 and without preeclampsia. Chronic arterial hypertension prevailed in women with positive SARS-CoV-2 and preeclampsia by 2.5 times in comparison with those with negative SARS-CoV-2 and preeclampsia, and by 10.4 times in comparison with those with positive SARS-CoV-2 and without preeclampsia. Assisted reproductive technologies were used for pregnant women with positive SARS-CoV-2 and preeclampsia 7.9 and 11.8 times more frequently than for other groups of women. Women with preeclampsia suffered from premature birth, premature detachment of the placenta, cesarean delivery, and asphyxia of newborns at a higher rate.","PeriodicalId":413800,"journal":{"name":"Vestnik SurGU. Meditsina","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122211234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0