Mathews Journal of Immunology & Allergy最新文献

{"title":"Aftershock of a Vaccination Gap: The Measles Epidemics in Tirana, 2018","authors":"D. Ulqinaku, Gentian Vyshka","doi":"10.30654/mjia.10013","DOIUrl":"https://doi.org/10.30654/mjia.10013","url":null,"abstract":"Tirana, capital of Albania, has seen an acute increase in the measles cases during 2018, with a total figure surpassing 1000 of patients. The outbreak happened while the country was only witnessing very few and isolated cases for several years, as to have officially declared the disease as eradicated. Several reasons might have led to the outbreak of this epidemic, with a clear vaccination gap in the years 1997-1998. Authors discuss this undervaccination as well as other factors detectable in this group of patients, such as a peak in the first-year age infants and the prevalent distribution in the suburban area of the city, actually inhabited from a large number of internally migrated people. (JMIR Preprints 28/05/2021:30779) DOI: https://doi.org/10.2196/preprints.30779 Preprint Settings 1) Would you like to publish your submitted manuscript as preprint? Please make my preprint PDF available to anyone at any time (recommended). Please make my preprint PDF available only to logged-in users; I understand that my title and abstract will remain visible to all users. Only make the preprint title and abstract visible. No, I do not wish to publish my submitted manuscript as a preprint. 2) If accepted for publication in a JMIR journal, would you like the PDF to be visible to the public? Yes, please make my accepted manuscript PDF available to anyone at any time (Recommended). Yes, but please make my accepted manuscript PDF available only to logged-in users; I understand that the title and abstract will remain visible to all users (see Important note, above). I also understand that if I later pay to participate in <a href=\"https://jmir.zendesk.com/hc/en-us/articles/360008899632-What-is-the-PubMed-Now-ahead-of-print-option-when-I-pay-the-APF-\" target=\"_blank\">JMIR’s PubMed Now! service</a> service, my accepted manuscript PDF will automatically be made openly available. Yes, but only make the title and abstract visible (see Important note, above). I understand that if I later pay to participate in <a href=\"https://jmir.zendesk.com/hc/en-us/articles/360008899632-What-is-the-PubMed-Now-ahead-of-print-option-when-I-pay-the-APF-\" target=\"_blank\">JMIR’s PubMed Now! service</a> service, my accepted manuscript PDF will automatically be made openly available. https://preprints.jmir.org/preprint/30779 [unpublished, non-peer-reviewed preprint] JMIR Preprints Ulqinaku et al","PeriodicalId":413658,"journal":{"name":"Mathews Journal of Immunology & Allergy","volume":"103 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124582436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Literature Review of the Published Human Clinical Trials: On COVID-19 Vaccines","authors":"Sarah El-Nakeep","doi":"10.30654/mjia.10011","DOIUrl":"https://doi.org/10.30654/mjia.10011","url":null,"abstract":"Emergency situations as COVID-19 pandemic require emergency authorizations; these are intended to shorten the time for each of the phases of the clinical trials or as termed by Pfizer ‘Project Lightspeed’ [1]. The aim is to have an effective vaccine that could offer protection to the population and end the pandemic in the most urgent and efficient way possible, as time elapsed equals the loss of more lives.","PeriodicalId":413658,"journal":{"name":"Mathews Journal of Immunology & Allergy","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121031671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Opinion About the Importance of MBL in HIV/HHV-8 Coinfection","authors":"V. M. Morais, Maria Rosacirc, ngela Cunha Duarte Coelho","doi":"10.30654/mjia.10009","DOIUrl":"https://doi.org/10.30654/mjia.10009","url":null,"abstract":"Most of the primary infections caused by HHV-8 are asymptomatic, with viral syndrome characterized by fever, fatigue, lymphadenopathy, diarrhea, and skin rash [8]. However, after the emergence of HIV/AIDS there was a higher incidence of diseases associated with HHV-8 infection, in which the main manifestations are from the excess of cytokines, such as Castleman’s multicenter disease, and the formation of tumors, as primary effusion lymphoma and Kaposi’s sarcoma (KS) [9,10]. HHV-8 is associated with all forms of Kaposi’s sarcoma (KS), the classic, endemic, iatrogenic, and epidemic or HIV/AIDS-associated form [6,11,12], being the necessary etiological agent, but insufficient for the development of clinical manifestations [4,5,10].","PeriodicalId":413658,"journal":{"name":"Mathews Journal of Immunology & Allergy","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132776761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acquired C1-Esterase Inhibitor Deficiency Associated with Burkitt Lymphoma","authors":"J. Prichard, Delilah D Coconubo, M. Gero, B. Noorbehesht, Michelle B Azimov","doi":"10.30654/mjia.10008","DOIUrl":"https://doi.org/10.30654/mjia.10008","url":null,"abstract":"C1-esterase inhibitor deficiency results in recurrent episodes of angioedema. Acquired deficiency has been associated with B-cell lymphoproliferative disorders, rheumatologic diseases or, in a small proportion of patients, the cause remains unknown. Of the malignancies associated with acquired C1-esterase deficiency, indolent lymphomas and plasma cell disorders are the most common. Aggressive lymphomas are rarely reported in such cases. We report the association of Burkitt lymphoma, a highly aggressive B-cell malignancy, which evolved seven months after the initial symptoms of acquired angioedema in a fifty-five year old man. Following treatment of the lymphoma, episodes of angioedema ceased. An association of acquired angioedema with Burkitt lymphoma has not previously been reported.","PeriodicalId":413658,"journal":{"name":"Mathews Journal of Immunology & Allergy","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124540969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reticular Dysgenesis: Fiction or Reality in Morocco","authors":"S. Tshimanga, A. Fouad, K. Fakiri, N. Rada, G. Draiss, B. Edmou, M. Bouskraoui","doi":"10.30654/mjia.10012","DOIUrl":"https://doi.org/10.30654/mjia.10012","url":null,"abstract":"Severe combined immune deficits (SCID) are a group of rare yet the severest forms of primitive immune deficits. Reticular dysgenesis (RD) is a rare form of SCID characterized by lack of circulating T lymphocytes, severe congenital neutropenia, and sensorineural deafness. Mutations of the gene coding for adenylate kinase2 (AK2) have been identified as the molecular basis, and treatment consists in bone marrow transplantation. In this article, we report a case of reticular dysgenesis, a very rare condition in Morocco, and a review of the literature.","PeriodicalId":413658,"journal":{"name":"Mathews Journal of Immunology & Allergy","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127448751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}