V. M. Morais, Maria Rosacirc, ngela Cunha Duarte Coelho
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引用次数: 0
Abstract
Most of the primary infections caused by HHV-8 are asymptomatic, with viral syndrome characterized by fever, fatigue, lymphadenopathy, diarrhea, and skin rash [8]. However, after the emergence of HIV/AIDS there was a higher incidence of diseases associated with HHV-8 infection, in which the main manifestations are from the excess of cytokines, such as Castleman’s multicenter disease, and the formation of tumors, as primary effusion lymphoma and Kaposi’s sarcoma (KS) [9,10]. HHV-8 is associated with all forms of Kaposi’s sarcoma (KS), the classic, endemic, iatrogenic, and epidemic or HIV/AIDS-associated form [6,11,12], being the necessary etiological agent, but insufficient for the development of clinical manifestations [4,5,10].
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