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World Journal of Medical Oncology最新文献

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Low expression of TRIM74 predicted poor prognosis and promoted the proliferation and migration of liver cancer cells TRIM74的低表达预示着肝癌的不良预后，并促进肝癌细胞的增殖和迁移
World Journal of Medical Oncology Pub Date : 2024-01-10 DOI: 10.52338/wjoncgy.2023.1018
Xie Tan
{"title":"Low expression of TRIM74 predicted poor prognosis and promoted the proliferation and migration of liver cancer cells","authors":"Xie Tan","doi":"10.52338/wjoncgy.2023.1018","DOIUrl":"https://doi.org/10.52338/wjoncgy.2023.1018","url":null,"abstract":"The aim of this study was to investigate the expression and clinical significance of the Tripartite motif-containing 74 gene in liver cancer.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endometrial Serous Adenocarcinoma and Perineal Leiomyosarcoma: A rare case report of Synchronous Primaries 子宫内膜浆液性腺癌和会阴部线粒体肉瘤：同步原发的罕见病例报告
World Journal of Medical Oncology Pub Date : 2024-01-10 DOI: 10.52338/wjoncgy.2023.1016
Ebinesh A
{"title":"Endometrial Serous Adenocarcinoma and Perineal Leiomyosarcoma: A rare case report of Synchronous Primaries","authors":"Ebinesh A","doi":"10.52338/wjoncgy.2023.1016","DOIUrl":"https://doi.org/10.52338/wjoncgy.2023.1016","url":null,"abstract":"The simultaneous presentation of endometrial carcinoma and perineal leiomyosarcoma in a patient as a synchronous tumor is very rare.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"41 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Effect of Eupalinolide B on Amyotrophic Lateral Sclerosis : A Case Report 幼帕内酯 B 对肌萎缩性脊髓侧索硬化症的影响：病例报告
World Journal of Medical Oncology Pub Date : 2024-01-10 DOI: 10.52338/wjoncgy.2023.1019
Huaixiu Wang
{"title":"The Effect of Eupalinolide B on Amyotrophic Lateral Sclerosis : A Case Report","authors":"Huaixiu Wang","doi":"10.52338/wjoncgy.2023.1019","DOIUrl":"https://doi.org/10.52338/wjoncgy.2023.1019","url":null,"abstract":": To investigate the effect of Eupalinolide B (EB) on amyotrophic lateral sclerosis (ALS). Method: EB was administered 20 mg/d orally","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update on Current and Future Developments in Radiation Protection of Patients. 患者辐射防护当前和未来发展的最新情况。
World Journal of Medical Oncology Pub Date : 2024-01-10 DOI: 10.52338/wjoncgy.2023.1017
Som Biswas
{"title":"Update on Current and Future Developments in Radiation Protection of Patients.","authors":"Som Biswas","doi":"10.52338/wjoncgy.2023.1017","DOIUrl":"https://doi.org/10.52338/wjoncgy.2023.1017","url":null,"abstract":"In this review, we look upon the current literature on the advances in radiation production and prospective future developments.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140510715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Angiogenic switch is a potential step in the pathogenesis of COVID-Mouth via an interaction with ACE2/Furin receptors: Review Article 血管生成开关是通过与ACE2/Furin受体相互作用而导致COVID-Mouth发病的潜在步骤
World Journal of Medical Oncology Pub Date : 2022-08-25 DOI: 10.52338/wjoncgy.2022.1010
Hala H Hazzaa, Gasser M Elewa, N. M. Elwakeel, Mai S. Attia
{"title":"Angiogenic switch is a potential step in the pathogenesis of COVID-Mouth via an interaction with ACE2/Furin receptors: Review Article","authors":"Hala H Hazzaa, Gasser M Elewa, N. M. Elwakeel, Mai S. Attia","doi":"10.52338/wjoncgy.2022.1010","DOIUrl":"https://doi.org/10.52338/wjoncgy.2022.1010","url":null,"abstract":"The current threats of coronavirus mainly cause respiratory infections in addition to their multi-system exposure potential including severe and distressing oral problems. In view of the rising documented oral lesions of COVID-19, this article aims to assess the underlying etiology of oral complications. An extensive literature search was conducted in PubMed","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127146516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Metastasis of Esophago-Gastric Cancers: Case series with review of literature 罕见的食管胃癌转移:病例系列并文献复习
World Journal of Medical Oncology Pub Date : 2022-07-19 DOI: 10.52338/wjoncgy.2022.1009
M. Khalaf, M. El-Matbouly, A. Suliman, A. Al-Bahrani
{"title":"Rare Metastasis of Esophago-Gastric Cancers: Case series with review of literature","authors":"M. Khalaf, M. El-Matbouly, A. Suliman, A. Al-Bahrani","doi":"10.52338/wjoncgy.2022.1009","DOIUrl":"https://doi.org/10.52338/wjoncgy.2022.1009","url":null,"abstract":"Purpose: in this case series we aim to highlight rare metastasis of gastric and esophageal cancers metastasizing to unusual locations causing a diagnostic challenge on presentation. We also review pertinent literature of rare locations of metastasis of gastro-esophageal cancer (GEC). Materials and methods: this is a retrospective analysis of four patients managed at our institution with one year follow up between 2020-2021. We include baseline patient characteristics, presenting symptoms, diagnostic work up and management of each individual case. Results: Out of the 4 cases with GEC; two had gastric adenocarcinoma, one esophageal adenocarcinoma and one gastroesophageal junction adenocarcinoma which metastasized to various locations throughout the body. Among the rarest locations of metastasis of gastric cancer is skeletal muscles. The locations of metastases were: ovaries and peritoneum from gastric adenocarcinoma, brain and liver from gastric adenocarcinoma, skeletal muscles from esophageal adenocarcinoma, and skeletal muscles and breast from GEC adenocarcinoma. The main diagnostic tool to identify these rare sites metastasis was Positron emission tomography scan (PET/CT). Conclusion: Studies have shown that not all gastroesophageal malignancies present with these alarm symptoms and up to 40% of patient can present without alarming symptoms. In our study; we shed the light on the possible rare metastatic sites that could have been missed with the regular presentation. Some of the rarest location of metastasis is to the skeletal muscles, which was present in two of our patients with an origin of gastric and esophageal cancer, which was identified with PET/CT. This study clarifies the importance of including whole body PET/CT scan in the staging process for patients with esophageal and gastric cancers to identify such rare sites metastasis that will alter the stage and clinical management of GEC patients.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131239634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
SYNCHRONOUS AND METACHRONOUS TUMORS OF THE BILIARY TREE. 胆道的同步和异时性肿瘤。
World Journal of Medical Oncology Pub Date : 2022-07-08 DOI: 10.52338/wjoncgy.2022.1008
H. Rajekar
{"title":"SYNCHRONOUS AND METACHRONOUS TUMORS OF THE BILIARY TREE.","authors":"H. Rajekar","doi":"10.52338/wjoncgy.2022.1008","DOIUrl":"https://doi.org/10.52338/wjoncgy.2022.1008","url":null,"abstract":"Biliary tract cancers arise in the biliary tract epithelium and include intrahepatic cholangiocarcinoma, perihilar cholangiocarcinoma, distal extrahepatic cholangiocarcinoma, and gallbladder cancer. These sites are anatomically contiguous and may appear related, but they are heterogeneous with distinct genetic and molecular signatures. Cholangiocarcinoma is the malignant tumor arising from the epithelium of the biliary tract, first histologically described by Durand-Fardel in 1840. Classification as originating from the intra- and extrahepatic biliary epithelium1 is a common way of classifying these tumors as prognosis and behavior are different in both types. Extrahepatic cholangiocarcinomas are further separated like the Bismuth classification; into upper-third or perihilar (including the confluence of the right and left biliary ducts) tumors; middle-third tumors; and distal bile duct tumors. Performance of a marginnegative resection with regional lymphadenectomy remains the cornerstone of successful treatment of cholangipcarcinoma.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124639895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the synergic effect of Avastin and VEGF siRNA on inhibition of the cell proliferation, invasion and angiogenic factor expression of human breast cancer cells 阿瓦斯汀与VEGF siRNA协同抑制人乳腺癌细胞增殖、侵袭及血管生成因子表达的作用
World Journal of Medical Oncology Pub Date : 2022-06-14 DOI: 10.52338/wjoncgy.2022.1011
A. Deezagi
{"title":"Assessment of the synergic effect of Avastin and VEGF siRNA on inhibition of the cell proliferation, invasion and angiogenic factor expression of human breast cancer cells","authors":"A. Deezagi","doi":"10.52338/wjoncgy.2022.1011","DOIUrl":"https://doi.org/10.52338/wjoncgy.2022.1011","url":null,"abstract":"Vascular endothelial growth factor (VEGF) is a key factor in angiogenesis, tumor growth and metastasis. Various small molecules and several humanized monoclonal antibodies against VEGF have been developed for inhibition of angiogenesis in different cancers. The aim of this work was to investigate the effect of combination of VEGF siRNA and Avastin on breast cancer MCF-7 cell line behavior.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132185100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual case of cutaneous desmoplastic melanoma 罕见的皮肤促结缔组织增生黑色素瘤病例
World Journal of Medical Oncology Pub Date : 2020-05-20 DOI: 10.52338/wjoncgy.2021.1006
S. D, Kantardjiev V, Broshtilova V
{"title":"An unusual case of cutaneous desmoplastic melanoma","authors":"S. D, Kantardjiev V, Broshtilova V","doi":"10.52338/wjoncgy.2021.1006","DOIUrl":"https://doi.org/10.52338/wjoncgy.2021.1006","url":null,"abstract":"Desmoplastic malignant melanoma (DMM) is an extremely rare subtype, encompassing up to 1% of all melanoma cases, worldwide. DMM features a prolonged clinical course and a variable clinical picture, which usually delays the exact diagnosis. The main differentiation from common malignant melanoma includes local recurrence rate, lymph node and distant organs involvement. DMM is further histologically divided into two subtypes – pure DMM and mixed / partial/ combined DMM. The division is important part of the diagnostic verification since these variants demonstrate different biological behavior and prognosis. Herein, a clinical case of a clinically atypical, pure desmoplastic malignant melanoma, occurring in a relatively young patient, is presented. A comprehensive overview highlights the most important DMM epidemiological, clinical and histological characteristics.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130260237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complicated Adult Midgut Malrotation: A Challenge to Diagnose and Treat 复杂成人中肠旋转不良:诊断和治疗的挑战
World Journal of Medical Oncology Pub Date : 2020-05-20 DOI: 10.52338/wjoncgy.2021.1005
C. Avgoustou, C. Avgoustou
{"title":"Complicated Adult Midgut Malrotation: A Challenge to Diagnose and Treat","authors":"C. Avgoustou, C. Avgoustou","doi":"10.52338/wjoncgy.2021.1005","DOIUrl":"https://doi.org/10.52338/wjoncgy.2021.1005","url":null,"abstract":"Midgut malrotation (MGM) refers to a broad spectrum of rotation and fixation anomalies of the gut during fetal development, which are clinically evident mostly early in life as newborn emergencies and rarely later as milder forms in adults. Most commonly, adult patients are asymptomatic throughout life or they are insidiously presenting unspecific symptoms for a significant period of time before the diagnosis is made. Less commonly, adult MGM cases are acutely complicated with challenging and life-threatening conditions, such as the obstructive midgut or right colon volvulus and the ileocolonic intussusception, which require prompt diagnosis, intensive resuscitation and emergent surgical intervention. Intentionally, high index of suspicion and awareness are essential, if bowel infarction is to be prevented and high morbidity and mortality reduced.","PeriodicalId":413116,"journal":{"name":"World Journal of Medical Oncology","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2020-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122784503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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