Journal of Zabol Medical School最新文献

Molecular Identification of the Gag and Tax Gene of Bovine Leukemia Virus (BLV) in Women with Breast Cancer 乳腺癌妇女体内牛白血病病毒 (BLV) Gag 和 Tax 基因的分子鉴定

Journal of Zabol Medical School Pub Date : 2024-05-21 DOI: 10.18502/jzms.v6i4.15485

Hassan Vahidi Emami, A. G. Langeroudi, Seyed Masoud Hosseini, H. Najafi, Z. Kafi, Soroush Sarmadi

{"title":"Molecular Identification of the Gag and Tax Gene of Bovine Leukemia Virus (BLV) in Women with Breast Cancer","authors":"Hassan Vahidi Emami, A. G. Langeroudi, Seyed Masoud Hosseini, H. Najafi, Z. Kafi, Soroush Sarmadi","doi":"10.18502/jzms.v6i4.15485","DOIUrl":"https://doi.org/10.18502/jzms.v6i4.15485","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Background: Breast cancer is one of the most common cancers in the world particularly among Iranian women. Although the mortality rate decreased in developed countries, there were increased changes in breast cancer incidences. The study aimed at evaluating the correlation between BLV infection and breast cancer in Iran. \u0000 \u0000 \u0000 \u0000 \u0000Methods: In the cross-sectional study, a total of 85 breast cancer tissue samples and adjacent tumor samples (normal tissue) were collected during the year 2022 from women referred to general hospitals in Qom Province, Iran. The nested PCR technique was performed to determine the presence of tax and gag genes of BLV in the collected samples. To confirm the presence of the tax gene of BLV, PCR products of some BLV-positive samples were subjected to direct sequencing. \u0000 \u0000 \u0000 \u0000 \u0000Results: Based on nested PCR technique, tax and gag genes of BLV were detected in 12.9% (11.85) and 3.4% (3.85) of breast cancer tissue samples, respectively. Also, the tax gene was present in 4.7% of the control samples, but the presence of the gag gene was not observed. Most malignant samples of BLV were III grade. The constructed phylogenetic trees for the tax gene of BLV showed most BLV isolates had similar sequences to Iranian isolates. \u0000 \u0000 \u0000 \u0000 \u0000Conclusion: The results of the study by using nested PCR technique, demonstrate a possible relationship between human breast cancer and bovine leukemia virus infection in women of Iran. BLV is one of the main risk factors for breast cancer. \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000 \u0000","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"125 26","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elderly Satisfaction and Related Factors from the Physical Structure of Kashan Hospitals 从卡尚医院的物质结构看老年人的满意度及相关因素

Journal of Zabol Medical School Pub Date : 2024-05-21 DOI: 10.18502/jzms.v6i4.15494

F. Izadi-Avanji, Azam Fotovati, Mohsen Taghaddosi, Amene Taghdisi

{"title":"Elderly Satisfaction and Related Factors from the Physical Structure of Kashan Hospitals","authors":"F. Izadi-Avanji, Azam Fotovati, Mohsen Taghaddosi, Amene Taghdisi","doi":"10.18502/jzms.v6i4.15494","DOIUrl":"https://doi.org/10.18502/jzms.v6i4.15494","url":null,"abstract":"Background: Satisfaction of hospitalized elderly can indicate the success of health system in providing health care. The study aimed to determine the hospitalized elderly's satisfaction and related factors with the physical structure of hospitals affiliated to Kashan University of Medical Sciences, 2022. \u0000Methods: This cross-sectional study was conducted on 650 elderly admitted to hospitals in Kashan from 2022 to 2023. Sampling was the Convenience method. The developed researchers' valid and reliable questionnaires were used to collect data. Data were analyzed with Pearson's correlation coefficient, independent t-test, one-way analysis of variance (ANOVA), and linear regression tests in SPSS version 16. \u0000Results: The mean age of the elderly was 71.7 ± 6.2 years. The mean score of elderly satisfaction was 24.6 ± 3.8 points on a scale of 0 to 45. The increasing age of the elderly had a statistically significant with the elderly satisfaction with the structure of hospitals (r = -0.12, P = 0.003). Multiple regression showed that the hospital specialization (P > 0.001) or being general (P > 0.001), marital status (P = 0.001), having movement problems (P = 0.001), education level (P > 0.001) and type of insurance (P = 0.005) as predictor variables explains 36% of the variance of elderly people's satisfaction with the physical structure of hospitals. \u0000Conclusion: The inappropriateness of the physical structure of hospitals causes dissatisfaction among the older adults. Hospital specialization, literacy level, marital status, movement problems, and insurance support are related to the hospitalized elderly’s satisfaction. It is necessary reforms the structure of hospitals to increase the satisfaction of older adults and prevent possible risks.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"33 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141117094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of the Frequency of Lung cancer in Kurdistan Province During 2005-2016 2005-2016 年间库尔德斯坦省肺癌发病率的变化情况

Journal of Zabol Medical School Pub Date : 2024-05-21 DOI: 10.18502/jzms.v6i4.15498

Sabbah Hasani, Ebrahim Ghaderi, Rezvan Parkalian, Bizhan Nouri, M. Parvareh, Pezhman Sharifi

{"title":"Incidence of the Frequency of Lung cancer in Kurdistan Province During 2005-2016","authors":"Sabbah Hasani, Ebrahim Ghaderi, Rezvan Parkalian, Bizhan Nouri, M. Parvareh, Pezhman Sharifi","doi":"10.18502/jzms.v6i4.15498","DOIUrl":"https://doi.org/10.18502/jzms.v6i4.15498","url":null,"abstract":"Background: Cancer is one of the principal causes of death in most countries of the world. Lung cancer is the deadliest and most expensive cancer in the world. In this study, the incidence of lung cancer in Kurdistan province was investigated for the first time in a specific period. \u0000Methods: In this cross-sectional study, 815 cases of lung cancer were investigated in Kurdistan province between 2005 and 2016. Reported cases of lung cancer were extracted at the Cancer Registry Center by gender, age, and morphology. Considering the population of 2005 as the standard population, the expected incidence rate was calculated, and the standardized incidence rate was estimated directly. \u0000Results: The results showed that the highest incidence of lung cancer was observed in 2016 and 2014 with 153 and 136 cases, respectively, and the lowest in 2009 and 2005, with 11 and 18 cases, respectively. The frequency of cases was observed in the age groups of 75-79 years in 2012 with 23 cases (22.77%) and in the age group of 70-74 years with 28 cases (18.30%) in 2016. The highest crude incidence was observed in 1394 with 12.47 and the lowest in 2013 with 1.10. \u0000Conclusion: According to the results of the present study, the incidence of lung cancer was higher in men than women and the incidence of the disease was higher in older ages. Analytical studies are necessary to find the causes of the disease and solve the problems related to this disease.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"122 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epidemiological Study of the Causes of Alcohol Drinks in Cases of Alcohol Poisoning among Patients who Referred to Amir Al-Momenin Hospital in Zabol in 2016-2019 2016-2019 年扎布尔市阿米尔-穆明宁医院转诊的酒精中毒病例中饮酒原因的流行病学研究

Journal of Zabol Medical School Pub Date : 2024-05-21 DOI: 10.18502/jzms.v6i4.15496

Khadijeh Saravani, Leili Rezaie Kahkhaie, Morteza Shahroudi

{"title":"Epidemiological Study of the Causes of Alcohol Drinks in Cases of Alcohol Poisoning among Patients who Referred to Amir Al-Momenin Hospital in Zabol in 2016-2019","authors":"Khadijeh Saravani, Leili Rezaie Kahkhaie, Morteza Shahroudi","doi":"10.18502/jzms.v6i4.15496","DOIUrl":"https://doi.org/10.18502/jzms.v6i4.15496","url":null,"abstract":"Background: Abuse of substances such as alcohol as a social issue affects the health of human life. In this study, we decided to address the prevalence of alcohol poisoning and its effective factors among patients referred to Amir Al-Momenin Hospital in Zabol. \u0000Methods: In this cross-sectional study, 110 patients with alcohol poisoning who had referred to Amir Al-Momenin Hospital in Zabol in 2016-2019 participated. Necessary information was collected through a questionnaire. Finally, the obtained data were statistically analyzed by T-test, Chi-square and Fisher's exact tests. \u0000Results: In the present study, 110 patients with alcohol poisoning were included in the study, of which 91 (82.72%) had ethanol poisoning and 19 (17.27%) had methanol poisoning. The mean age of patients was 27.08 ± 3.2 years and 95.45% of them were male. Unemployment and lack of entertainment, mental disorders, alcoholic friends, psychological dependence were the most common causes of alcohol consumption in patients. In this study, decreased level of consciousness (57.27%) and gastrointestinal complications (43.63%) were the most common symptoms of alcohol poisoning in the studied patients. \u0000Conclusion: In the present study, male gender was significantly associated with alcohol poisoning (P). While the variables of age, sex and marital status were not significantly associated with the type of ethanol or methanol poisoning. The results of the study showed that male gender, social status and low education of parents, psychological problems and alcohol friends were risk factors and influential factors in alcohol poisoning.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"83 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141116498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Antimicrobial and Antifungal Effects of Ag and Mg Dual-Doped Zinc Oxide Nanoparticles against Staphylococcus Epidermidis, Pseudomonas Aeruginosa, and Candida Albicans 评估银镁双掺氧化锌纳米粒子对表皮葡萄球菌、绿脓杆菌和白色念珠菌的抗菌和抗真菌作用

Journal of Zabol Medical School Pub Date : 2024-05-21 DOI: 10.18502/jzms.v6i4.15495

K. Hamidian, Mostafa Azizi

{"title":"Evaluation of Antimicrobial and Antifungal Effects of Ag and Mg Dual-Doped Zinc Oxide Nanoparticles against Staphylococcus Epidermidis, Pseudomonas Aeruginosa, and Candida Albicans","authors":"K. Hamidian, Mostafa Azizi","doi":"10.18502/jzms.v6i4.15495","DOIUrl":"https://doi.org/10.18502/jzms.v6i4.15495","url":null,"abstract":"Background: Microbial infectious diseases are one of the serious health problems that have attracted the attention of the public as a threat to human health all over the world. Zinc oxide nanoparticles due to their various properties such as antibacterial, antifungal, and anticancer are of great interest. \u0000Methods: The antimicrobial activity of synthesized un-doped and silver and magnesium-doped zinc oxide nanoparticles with Salvadora persica extract against different strains of Staphylococcus epidermidis, Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans was investigated through two methods of broth diffusion and the minimum microbial inhibitory concentration (MIC). \u0000Results: According to results, MIC of un-doped and silver and magnesium-doped zinc oxide nanoparticles showed 160, 80, 40, and 40 µg/mL on Staphylococcus epidermidis, and 80, 40, 40, and 40 µg/mL on Staphylococcus aureus. These values on Pseudomonas aeruginosa were obtained ˃5120, 640, 320, and 320 µg/mL. \u0000Conclusion: The results of the broth dilution method on Staphylococcus epidermidis and Staphylococcus aureus showed the presence of silver has a very good inhibition effect on these bacteria. In Pseudomonas aeruginosa and Candida albicans fungus, it has been observed that by increasing the amount of silver and magnesium doping, the inhibitory rate of nanoparticles on Gram-negative bacteria and fungi has increased.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"140 19","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141114673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Mediating Role of Health-Promoting Lifestyle in the Relationship between Physical Activity Level and Anxiety in Adults of Sistan and Baluchistan Province 促进健康的生活方式在锡斯坦和俾路支斯坦省成年人体育活动水平与焦虑之间关系中的中介作用

Journal of Zabol Medical School Pub Date : 2024-05-21 DOI: 10.18502/jzms.v6i4.15497

Abdulaziz Rezazai, S. Mirkazemi, Mohammad Hossein Salari Far

{"title":"The Mediating Role of Health-Promoting Lifestyle in the Relationship between Physical Activity Level and Anxiety in Adults of Sistan and Baluchistan Province","authors":"Abdulaziz Rezazai, S. Mirkazemi, Mohammad Hossein Salari Far","doi":"10.18502/jzms.v6i4.15497","DOIUrl":"https://doi.org/10.18502/jzms.v6i4.15497","url":null,"abstract":"Background: The purpose of the study was to investigate the mediating role of health-promoting lifestyle in the relationship between physical activity level and anxiety in adults of Sistan and Baluchistan. \u0000Methods: The method of research was descriptive and its design was of the correlation, which was carried out by the field. The statistical population included adults (15 years old and above) among them 360 people in the cities of Saravan, Chabahar, Zahedan, and Soran by Cluster sampling were selected. To collect the data, the standard health-promoting lifestyle questionnaires of Walker et al. (1997), Spielberger's anxiety (1970), and IPAQ Physical activity were used. Data analysis was done using descriptive statistics and structural equation modeling with AMOS. \u0000Results: The results showed that physical activity has a direct and significant effect on the health-promoting lifestyle, the effect of physical activity on anxiety was negative and significant, effect of health-promoting style on anxiety was observed to be negative and significant. The results showed an indirect and significant effect of physical activity on anxiety through a health-promoting lifestyle. \u0000Conclusion: Findings show the importance of a health-promoting lifestyle as a mediator in reducing anxiety; therefore, improving lifestyle will facilitate the effect of physical activity on reducing anxiety.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"105 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141115959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigating the Effect of Lippia Citriodora Leaf Hydro-Ethanolic Extract on Two Prostate Cancer Cell Lines PC-3 and LNCaP Alone and in Combination with Docetaxel 研究柠条叶水乙醇提取物单独或与多西他赛联合使用对两种前列腺癌细胞系 PC-3 和 LNCaP 的影响

Journal of Zabol Medical School Pub Date : 2024-01-28 DOI: 10.18502/jzms.v6i3.14794

Mehdi Fazeli

{"title":"Investigating the Effect of Lippia Citriodora Leaf Hydro-Ethanolic Extract on Two Prostate Cancer Cell Lines PC-3 and LNCaP Alone and in Combination with Docetaxel","authors":"Mehdi Fazeli","doi":"10.18502/jzms.v6i3.14794","DOIUrl":"https://doi.org/10.18502/jzms.v6i3.14794","url":null,"abstract":"Background: Prostate cancer is the most common cancer in men. Docetaxel is the most important drug for prostate cancer, but drug resistance reduces its effectiveness. One of the important strategies to increase the drug efficacy is the use of combination therapy. This study investigated toxic effect of Lippia citriodora leaf extract on two prostate cancer cell lines and its effect on docetaxel cytotoxicity. \u0000Methods: Cytotoxicity of Lippia citriodora leaf extract was evaluated individually or in combination with docetaxel. Cells were cultured in 96-well plates. After treating cells with different concentrations of extracts and drugs, their survival was measured by MTT assay. \u0000Results: Lippia citriodora leaf extract showed a highly toxic effect on prostate cancer cells. The extract at the highest concentration, decreased the percentage of viable cells to 18.01 ± 1.37 in PC-3 cells and to 20.80 ± 1.06 in LNCaP cells. The IC50 value of the extract was 78.14 mg/ml for PC-3 cells and 88.76 mg/ml for LNCaP cells. In addition, the extract increased the cytotoxicity of docetaxel. In the maximum increasing effect, the percentage of survival in PC-3 and LNCaP cells decreased from 50.87 ± 2.46 to 26.48 ± 1.12 and from 54.13 ± 1.83 to 28.84 ± 1.69, respectively. \u0000Conclusion: Lippia citriodora leaf extract had a remarkable toxic effect on prostate cancer cells in vitro and increased docetaxel cytotoxicity. The antitumor effects of the extract can be further evaluated in vivo and clinical trials.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"346 10-11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140490862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the Effect of Two Drug Combinations: Ketamine-Midazolam -Sufentanil with Etomidate-Sufentanil on Changes in Heart Rate and Blood Pressure After Laryngoscopy and Endotracheal Intubation 两种药物组合对喉镜检查和气管插管后心率和血压变化的影响比较：氯胺酮-咪达唑仑-舒芬太尼与依托咪酯-舒芬太尼对喉镜检查和气管插管后心率和血压变化的影响比较

Journal of Zabol Medical School Pub Date : 2024-01-28 DOI: 10.18502/jzms.v6i3.14795

A. Honarmand, Kimia Karimian, M. Safavi, H. Shetabi, Alireza Yazdani

{"title":"Comparison of the Effect of Two Drug Combinations: Ketamine-Midazolam -Sufentanil with Etomidate-Sufentanil on Changes in Heart Rate and Blood Pressure After Laryngoscopy and Endotracheal Intubation","authors":"A. Honarmand, Kimia Karimian, M. Safavi, H. Shetabi, Alireza Yazdani","doi":"10.18502/jzms.v6i3.14795","DOIUrl":"https://doi.org/10.18502/jzms.v6i3.14795","url":null,"abstract":"Background: Due to the high prevalence of complications during and after laryngoscopy, especially hemodynamic disturbances, and the absence of a suitable solution for preventing these complications, this study was conducted to compare the effect of “Ketamine-Midazolam-Sufentanil” with “Etomidate-Sufentanil” combinations on changes in heart rate and blood pressure after laryngoscopy and endotracheal intubation. \u0000Methods: In this controlled, triple-blind randomized clinical trial, 96 laryngoscopy candidate patients were divided into three groups of 32 members and were given “Ketamine-Midazolam-Sufentanil” (KMS), “Etomidate-Sufentanil” (ES) and” Etomidate- Normal Saline” (NS) respectively before laryngoscopy. Hemodynamic parameter changes at baseline and 1,3,5 and 10 minutes after laryngoscopy, were measured and compared between the 3 groups. \u0000Results: During the study, the 3 groups KMS, ES, and NS had 0%, 15.6% and, 3.1% bradycardia respectively (p value = 0.024). Changes in systolic blood pressure were significantly different in the 3 groups (p value = 0.043). However, the incidence of tachycardia, hypertension, and hypotension were not significantly different among the 3 groups. \u0000Conclusion: Results of this study showed that using the “Ketamine-Midazolam-Sufentanil” combination before laryngoscopy can reduce hemodynamic disturbances during and after laryngoscopy. Patients who receive this drug combination seem to have more desirable hemodynamic stability during and after laryngoscopy.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"11 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139592076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of 5-Year Survival Rate of Patients with Multiple Myeloma Undergoing Bone Marrow Transplantation: A Descriptive Study 评估接受骨髓移植的多发性骨髓瘤患者的 5 年生存率：描述性研究

Journal of Zabol Medical School Pub Date : 2024-01-28 DOI: 10.18502/jzms.v6i3.14796

Ali Nemati, Elahenaz Parsi Mood, Shirin Raghi, Vahid Moazed

{"title":"Evaluation of 5-Year Survival Rate of Patients with Multiple Myeloma Undergoing Bone Marrow Transplantation: A Descriptive Study","authors":"Ali Nemati, Elahenaz Parsi Mood, Shirin Raghi, Vahid Moazed","doi":"10.18502/jzms.v6i3.14796","DOIUrl":"https://doi.org/10.18502/jzms.v6i3.14796","url":null,"abstract":"Background: Multiple myeloma is a progressive and high mortality neoplasm, and the prevalence increases with aging. The main treatment for new cases aged less than 65 years is high-dose chemotherapy with autologous bone marrow transplantation. This study aims to determine the five-year survival rate of patients with multiple myeloma. \u0000Methods: In this descriptive-analytical study, 97 patients with multiple myeloma who underwent bone marrow transplantation between 2011 and 2016 were investigated. Then, information related to gender, age at the time of transplantation, the time interval between diagnosis and transplantation, cases of death and, date of death of the studied patients were collected, and the survival of the patients from the date of diagnosis to the end of the study period (five years) was calculated. Data were analyzed using Cox proportional and chi-square tests. \u0000Results: Five-year survival of patients was 59.8%. The median overall survival of patients was 54.22 months, which shows that age (p value = 0.003), gender (p value = 0.591), and the time delay between diagnosis and bone marrow transplantation (p value = 0.005) all affect patient survival. There was a significant relationship between the patient's age and the time interval between diagnosis and transplantation with the five-year survival of the patients. \u0000Conclusion: As a result, bone marrow transplantation provides a higher survival rate. Also, the effect of the patient‘s age and time interval between diagnosis and transplantation, early diagnosis of the disease and, earlier bone marrow transplantation can bring longer survival for patients.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"5 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139592274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological and Psychological Investigation of Sexual Desire Disorder in Infertile Men Referred to Avicenna Infertility Treatment Center 转诊至阿维森纳不孕不育治疗中心的不育男性性欲障碍的生物学和心理学调查

Journal of Zabol Medical School Pub Date : 2024-01-28 DOI: 10.18502/jzms.v6i3.14799

Nasser Amirjanti, Behzad Ghorbani, Zahra Sehat, Saeed Razi

{"title":"Biological and Psychological Investigation of Sexual Desire Disorder in Infertile Men Referred to Avicenna Infertility Treatment Center","authors":"Nasser Amirjanti, Behzad Ghorbani, Zahra Sehat, Saeed Razi","doi":"10.18502/jzms.v6i3.14799","DOIUrl":"https://doi.org/10.18502/jzms.v6i3.14799","url":null,"abstract":"Background: Decreased sexual desire in infertile men, which sometimes leads to infertility, can open the way to choose between drug or psychotherapy treatments for these patients, compared to psychological causes. Therefore, the present study was conducted to compare biological and psychological evaluation in men with and without sexual desire disorder in infertile patients referred to Avicenna Infertility Treatment Center. \u0000Methods: A descriptive-analytical study was conducted on infertile men. The studied sample was estimated to be 128 people using G-power software, taking into account the first type error of 0.05, statistical power of 0.8, and effect size of 0.5, from the eligible infertile men by random sampling were chosen. Halbert's Sexual Desire Questionnaire (HISD) was used to measure sexual desire, and Zanke's standard questionnaire was used to measure anxiety. \u0000Results: In this study, 128 men were examined. Among these people, 39.8% had the cause of male infertility and 11.7% had the cause of female infertility. 3.1% of the people had cryptorchidism, 32% had a history of varicocele, and 7% mentioned infection. Zonk score classification in the participants in the study: 73.33 ± 21.62, normal anxiety, 60.28 ± 13.62, mild anxiety, 50.50 ± 22.63, severe anxiety, and 44.50 ± 16.54, very severe anxiety they had. Among the investigated variables, the level of anxiety and depression is more related to smoking, Cryptorchidism, no history of varicocele, or history of infection. \u0000Conclusion: Infertile men, in addition to reducing their cognitive well-being, suffer a heavy psychological burden that can cause dysfunction and a decrease in sexual desire.","PeriodicalId":410018,"journal":{"name":"Journal of Zabol Medical School","volume":"368 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140490914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0