Suez Canal University Medical Journal最新文献_第2页

Obesity among Rheumatoid Arthritis Patients and its Relation to Disease Activity: Cross-sectional Study among the Egyptian Population 类风湿关节炎患者的肥胖症及其与疾病活动的关系：埃及人口的横断面研究

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.342143

Elham A. Abdellatif, A. Omar, Afaf Z. Ahmed, Mai A. Abdellatif

{"title":"Obesity among Rheumatoid Arthritis Patients and its Relation to Disease Activity: Cross-sectional Study among the Egyptian Population","authors":"Elham A. Abdellatif, A. Omar, Afaf Z. Ahmed, Mai A. Abdellatif","doi":"10.21608/scumj.2024.342143","DOIUrl":"https://doi.org/10.21608/scumj.2024.342143","url":null,"abstract":"Background: The \"100 Million Health\" survey performed in 2019 in Egypt, which examined 49.7 million adult individuals aged 18 years and above, revealed that 39.8 percent have obesity, with female predominance. Further research into the effect of obesity in RA is necessary due to the established link between obesity and inflammation as well as changes in the body composition of RA patients. Objectives: To determine obesity prevalence in RA cases and its effect on the functional outcome as well as the disease activity score (DAS). Patients and Methods: The current cross-sectional study included 104 RA cases who met the 2010 ACR/EULAR classification criteria. Subjects underwent laboratory investigations, clinical examinations, and anthropometric measures (Body mass index BMI and waist circumference/hip circumference WC/HC ratio). Patient functional status was assessed utilizing the health assessment questionnaire disability index (HAQ-DI). Results: It was found that 23.1% of RA patients cases have average weight, while 27.9% were overweight and 49% were obese, with significant female predominance. There was a significant increase in the scores of HAQ-DI and DAS-28 in overweight as well as obese subjects than those with normal BMI. Conclusion: Obesity is prevalent in RA cases, and it substantially affects DAS-28 score and functional status.","PeriodicalId":407231,"journal":{"name":"Suez Canal University Medical Journal","volume":"74 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140520237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Immunohistochemical Expression of SOX2 and its Prognostic Significance in Prostatic Adenocarcinoma 评估前列腺腺癌中 SOX2 的免疫组化表达及其预后意义

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.343084

Dalia I. Mohamed, Amr A.M. Kamel, Mohamed K. E. Kherbetawy

{"title":"Assessment of Immunohistochemical Expression of SOX2 and its Prognostic Significance in Prostatic Adenocarcinoma","authors":"Dalia I. Mohamed, Amr A.M. Kamel, Mohamed K. E. Kherbetawy","doi":"10.21608/scumj.2024.343084","DOIUrl":"https://doi.org/10.21608/scumj.2024.343084","url":null,"abstract":"Background: SOX2 is a transcription factor involved in the self-renewal and pluripotency of embryonic stem cells (ESCs). It is involved in various cancer types and affects cancer cell physiology via involvement in complicated cell signaling and protein-protein interactions. im : Our work aimed to assess the expression patterns of SOX2 in prostatic adenocarcinoma in correlation with the histopathological findings to evaluate its role as a prognostic marker or possible therapeutic target. Materials and Methods: forty-eight specimens of prostatic adenocarcinoma were stained first H&E then immunohistochemically for SOX2 and scored by two histo-pathologists. Results: thirty-eight specimens showed positive nuclear expression of SOX2; with variable degrees. SOX2 expression showed a statistically significant association with different grade groups; with p-value = 0.025. There was no statistically significant association between its expression and the patient’s demographic data. Conclusion: Overexpression of SOX2 in Prostatic Adenocarcinoma could be an indicator of higher tumor grade and poor prognosis. It could be used as a prognostic biomarker for tumor aggressiveness.","PeriodicalId":407231,"journal":{"name":"Suez Canal University Medical Journal","volume":"15 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140519907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utility of Magnetic Resonance Spectroscopy and Diffusion Tensor Imaging of the Brain in Patients with Hashimoto’s Thyroiditis with Normal Appearing Conventional Brain MRI 磁共振波谱成像和脑弥散张量成像在常规脑磁共振成像显示正常的桥本氏甲状腺炎患者中的实用性

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.342710

Heba R. Ibrahim

引用次数: 0

Prevalence and Associated Factors of Erectile Dysfunction among Diabetic Patients Attending Primary Health Care Settings in Ismailia Governorate 伊斯梅利亚省初级保健机构就诊的糖尿病患者中勃起功能障碍的患病率和相关因素

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.199737.1420

Ehaab Abd allah

引用次数: 0

Efficacy and Safety of Dexmedetomidine Combined with Bupivacaine in Infants’ Surgeries: A Randomized Controlled Trial 右美托咪定联合布比卡因在婴儿手术中的有效性和安全性：随机对照试验

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.342791

Ahmed N. Negm

{"title":"Efficacy and Safety of Dexmedetomidine Combined with Bupivacaine in Infants’ Surgeries: A Randomized Controlled Trial","authors":"Ahmed N. Negm","doi":"10.21608/scumj.2024.342791","DOIUrl":"https://doi.org/10.21608/scumj.2024.342791","url":null,"abstract":"Background: Dexmedetomidine has been identified as a good sedative agent in adult patients. It is usually added to local anesthetic in spinal anesthesia (SA). However, its use as an adjuvant in infant surgeries has not been well studied due to the scarcity of data. Aim: In this study, we aim to investigate the efficacy and safety of dexmedetomidine combined with bupivacaine in SA. Materials and Methods: in this randomized clinical trial, we included 46 infants who underwent infra-umbilical surgeries. We allocated patients into two groups: group 1 received bupivacaine only, and group 2 received 0.3μg/kg dexmedetomidine in addition to bupivacaine 0.5%. We assessed efficacy through evaluation of the onset and duration of sensory and motor block and time to discharge from the post-anesthesia care unit (PACU), while safety was assessed through monitoring of hemodynamics and rate of complications. Results: we found that using 0 .3μg/kg dexmedetomidine in addition to bupivacaine 0.5% (group 2) was associated with a significantly prolonged duration of sensory and motor block compared to group 1. Time to discharge from PACU was earlier with group 2, but not significantly different from group 1. Although Group 1 did not witness any complications; group 2 had limited side effects that were managed appropriately. Conclusions: the combination of 0 .3μg/kg dexmedetomidine with bupivacaine is safe and efficient in the anesthesia of infants undergoing minor surgeries.","PeriodicalId":407231,"journal":{"name":"Suez Canal University Medical Journal","volume":"3 5-6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.342793

Mohamed S. Omar, Osama Elbassiouny, Hussein S. EL-Nahass, Tarak M. Radwan, Mervet E. Elgharib

引用次数: 0

Prevalence and Severity of Premenstrual Syndrome and Premenstrual Dysphoric Disorder among Physicians in Port Said City 赛义德港市医生中经前综合征和经前多愁善感症的患病率和严重程度

Suez Canal University Medical Journal Pub Date : 2024-01-01 DOI: 10.21608/scumj.2024.339596

Samy A. Abdelazim, Aliaa AM. Ibrahim, N. Eldahshan

引用次数: 0

Maternal Serum Vitamin D Level in Preeclampsia Versus Normotensive Pregnant Females: A Comparative Study 子痫前期与血压正常孕妇的母体血清维生素 D 水平：比较研究

Suez Canal University Medical Journal Pub Date : 2023-10-01 DOI: 10.21608/scumj.2023.329175

Nashwa Y. Hassan, Mohamed A. El-Bahey, Abeer B. Ahmed, Ahmed A. Abo Alroos

引用次数: 0

Evaluation of Non-Operative Management of Pediatric Acute Non-Complicated Appendicitis 小儿急性非并发症阑尾炎非手术治疗的评价

Suez Canal University Medical Journal Pub Date : 2023-07-01 DOI: 10.21608/scumj.2023.309502

Mohamed M Elzoghby, Mohammed Salah Ibrahim, A. Mobarak, T. Gobran, Karam Ahmed

引用次数: 0

Comparing the Therapeutic Efficacy of Intradermal Injection of Platelet-Rich Plasma and Topical Application of Hydroquinone 2% in Melasma Treatment 富血小板血浆皮内注射与2%对苯二酚外用治疗黄褐斑的疗效比较

Suez Canal University Medical Journal Pub Date : 2023-07-01 DOI: 10.21608/scumj.2023.309138

Hesham A. Nada, N. Ismail, Shaymaa A. Abd El Hady, A. F. Mohamed

引用次数: 0