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ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology最新文献

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Curcumin ameliorates experimental colitis by suppressing PERK-UPR-signaling pathway 姜黄素通过抑制perk - upr信号通路改善实验性结肠炎
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.163100
Islam I. Khan, Zahraa Baydoun, M. Rao
{"title":"Curcumin ameliorates experimental colitis by suppressing PERK-UPR-signaling pathway","authors":"Islam I. Khan, Zahraa Baydoun, M. Rao","doi":"10.1124/jpet.122.163100","DOIUrl":"https://doi.org/10.1124/jpet.122.163100","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122365837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A positive allosteric modulator of M1 Acetylcholine receptors improves cognitive deficits in male and female APPswe/PSEN1ΔE9 mice via divergent mechanisms M1乙酰胆碱受体的阳性变构调节剂通过不同的机制改善雄性和雌性APPswe/PSEN1ΔE9小鼠的认知缺陷
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.138300
Khaled S. Abd-Elrahman, Tash-Lynn L. Colson, Stephen S. G. Ferguson
{"title":"A positive allosteric modulator of M1 Acetylcholine receptors improves cognitive deficits in male and female APPswe/PSEN1ΔE9 mice via divergent mechanisms","authors":"Khaled S. Abd-Elrahman, Tash-Lynn L. Colson, Stephen S. G. Ferguson","doi":"10.1124/jpet.122.138300","DOIUrl":"https://doi.org/10.1124/jpet.122.138300","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"16 9","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131879643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying Acid Adaptivity of Normal and Cancer Cells Using a Next Generation Genetically Encoded pH Biosensor 利用新一代基因编码pH生物传感器定量测定正常细胞和癌细胞的酸适应性
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.283790
D. Isom, Sam Taylor, K. Lee, J. Rowe
{"title":"Quantifying Acid Adaptivity of Normal and Cancer Cells Using a Next Generation Genetically Encoded pH Biosensor","authors":"D. Isom, Sam Taylor, K. Lee, J. Rowe","doi":"10.1124/jpet.122.283790","DOIUrl":"https://doi.org/10.1124/jpet.122.283790","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"119 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131999243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heat shock protein 90 inhibition in the spinal cord upregulates Src kinase in microglia to enhance opioid antinociception in acute pain 脊髓热休克蛋白90抑制上调小胶质细胞Src激酶，增强急性疼痛中的阿片抗痛觉作用
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.137220
J. Bowden, J. Streicher
{"title":"Heat shock protein 90 inhibition in the spinal cord upregulates Src kinase in microglia to enhance opioid antinociception in acute pain","authors":"J. Bowden, J. Streicher","doi":"10.1124/jpet.122.137220","DOIUrl":"https://doi.org/10.1124/jpet.122.137220","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134349440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structural Basis of Arrestin and Membrane Interaction 阻滞蛋白与膜相互作用的结构基础
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.568360
Kyle W. Miller, Qiuyan Chen, Shuaitongze Zhao
{"title":"Structural Basis of Arrestin and Membrane Interaction","authors":"Kyle W. Miller, Qiuyan Chen, Shuaitongze Zhao","doi":"10.1124/jpet.122.568360","DOIUrl":"https://doi.org/10.1124/jpet.122.568360","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115107876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Ecdysterone on Dry Eye Syndrome In Vitro and In Vivo 蜕皮酮对干眼综合征的体内外作用
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.534360
B. Park
{"title":"Effect of Ecdysterone on Dry Eye Syndrome In Vitro and In Vivo","authors":"B. Park","doi":"10.1124/jpet.122.534360","DOIUrl":"https://doi.org/10.1124/jpet.122.534360","url":null,"abstract":"Abstract","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"138 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123666327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Protective Effects of Ozanimod in Cisplatin-induced Neuropathic Pain in Mice: Insights from Single-cell Transcriptomic Profiling in Spinal Cord Tissues Ozanimod对小鼠顺铂诱导的神经性疼痛的保护作用:来自脊髓组织单细胞转录组学分析的见解
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.563370
Y. Li, S. Squillace, L. Giancotti, TerranceM . Egan, Stella G Hoft, R. DiPaolo, D. Salvemini
{"title":"Protective Effects of Ozanimod in Cisplatin-induced Neuropathic Pain in Mice: Insights from Single-cell Transcriptomic Profiling in Spinal Cord Tissues","authors":"Y. Li, S. Squillace, L. Giancotti, TerranceM . Egan, Stella G Hoft, R. DiPaolo, D. Salvemini","doi":"10.1124/jpet.122.563370","DOIUrl":"https://doi.org/10.1124/jpet.122.563370","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"58 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120957129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative phosphoproteomic analysis defines distinct cAMP signaling networks emanating from AC2 and AC6 in human airway smooth muscle cells 定量磷蛋白组学分析确定了人类气道平滑肌细胞中由AC2和AC6发出的不同cAMP信号网络
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.147910
I. Cattani-Cavalieri, Yue Li, Jordyn Margolis, Amy S. Bogard, Moom R. Roosan, R. Ostrom
{"title":"Quantitative phosphoproteomic analysis defines distinct cAMP signaling networks emanating from AC2 and AC6 in human airway smooth muscle cells","authors":"I. Cattani-Cavalieri, Yue Li, Jordyn Margolis, Amy S. Bogard, Moom R. Roosan, R. Ostrom","doi":"10.1124/jpet.122.147910","DOIUrl":"https://doi.org/10.1124/jpet.122.147910","url":null,"abstract":"ID 14791","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127219651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pharmacological Modulation of Hsp70 to Selectively Remove Misfolded Neuronal Nitric Oxide Synthase Hsp70选择性去除错误折叠神经元一氧化氮合酶的药理调节
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.235890
Anthony Garcia, E. Xu, Miranda Lau, A. Alt, Andrew Lieberman, Yoichi Osawa
{"title":"Pharmacological Modulation of Hsp70 to Selectively Remove Misfolded Neuronal Nitric Oxide Synthase","authors":"Anthony Garcia, E. Xu, Miranda Lau, A. Alt, Andrew Lieberman, Yoichi Osawa","doi":"10.1124/jpet.122.235890","DOIUrl":"https://doi.org/10.1124/jpet.122.235890","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130758615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delineation of the G Protein-Coupled Receptor Kinase Phosphorylation Sites Within the D1 Dopamine Receptor and Their Role in Regulating Receptor Function D1多巴胺受体内G蛋白偶联受体激酶磷酸化位点的描述及其在调节受体功能中的作用
ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology Pub Date : 2023-05-18 DOI: 10.1124/jpet.122.154110
Nora S. Madaras, M. Rankin, R. Free, R. Haider, J. Drube, Arun K. Ghosh, John J. G. Tesmer, Carsten Hoffmann, David R. Sibley, Amy E. Moritz
{"title":"Delineation of the G Protein-Coupled Receptor Kinase Phosphorylation Sites Within the D1 Dopamine Receptor and Their Role in Regulating Receptor Function","authors":"Nora S. Madaras, M. Rankin, R. Free, R. Haider, J. Drube, Arun K. Ghosh, John J. G. Tesmer, Carsten Hoffmann, David R. Sibley, Amy E. Moritz","doi":"10.1124/jpet.122.154110","DOIUrl":"https://doi.org/10.1124/jpet.122.154110","url":null,"abstract":"","PeriodicalId":406842,"journal":{"name":"ASPET 2023 Annual Meeting Abstract - Cellular and Molecular Pharmacology","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117205140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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